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  1. Article ; Online: Tumor Size Is Not Everything: Advancing Radiomics as a Precision Medicine Biomarker in Oncology Drug Development and Clinical Care. A Report of a Multidisciplinary Workshop Coordinated by the RECIST Working Group.

    Nakajima, Erica C / Simpson, Amber / Bogaerts, Jan / de Vries, Elisabeth G E / Do, Richard / Garalda, Elena / Goldmacher, Greg / Kinahan, Paul E / Lambin, Philippe / LeStage, Barbara / Li, Qin / Lin, Frank / Litière, Saskia / Perez-Lopez, Raquel / Petrick, Nicholas / Schwartz, Lawrence / Seymour, Lesley / Shankar, Lalitha / Laurie, Scott A

    JCO precision oncology

    2024  Volume 8, Page(s) e2300687

    Abstract: Radiomics, the science of extracting quantifiable data from routine medical images, is a powerful tool that has many potential applications in oncology. The Response Evaluation Criteria in Solid Tumors Working Group (RWG) held a workshop in May 2022, ... ...

    Abstract Radiomics, the science of extracting quantifiable data from routine medical images, is a powerful tool that has many potential applications in oncology. The Response Evaluation Criteria in Solid Tumors Working Group (RWG) held a workshop in May 2022, which brought together various stakeholders to discuss the potential role of radiomics in oncology drug development and clinical trials, particularly with respect to response assessment. This article summarizes the results of that workshop, reviewing radiomics for the practicing oncologist and highlighting the work that needs to be done to move forward the incorporation of radiomics into clinical trials.
    MeSH term(s) Humans ; Precision Medicine/methods ; Response Evaluation Criteria in Solid Tumors ; Radiomics ; Medical Oncology ; Neoplasms/diagnostic imaging ; Neoplasms/drug therapy
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article
    ISSN 2473-4284
    ISSN (online) 2473-4284
    DOI 10.1200/PO.23.00687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Application of the Lugano Classification for Initial Evaluation, Staging, and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma: The PRoLoG Consensus Initiative (Part 1-Clinical).

    Ricard, Fabien / Cheson, Bruce / Barrington, Sally / Trotman, Judith / Schmid, Annette / Brueggenwerth, Guenther / Salles, Gilles / Schwartz, Larry / Goldmacher, Greg / Jarecha, Rudresh / Narang, Jayant / Broussais, Florence / Galette, Paul / Liu, Min / Bajpai, Surabhi / Perlman, Eric / Gillis, Julie / Smalberg, Ira / Terve, Pierre /
    Zahlmann, Gudrun / Korn, Ron

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    2022  Volume 64, Issue 1, Page(s) 102–108

    Abstract: Our objective was to provide consensus recommendations from a consortium of academic and industry experts in the field of lymphoma and imaging for consistent application of the Lugano classification. ...

    Abstract Our objective was to provide consensus recommendations from a consortium of academic and industry experts in the field of lymphoma and imaging for consistent application of the Lugano classification.
    MeSH term(s) Humans ; Positron Emission Tomography Computed Tomography ; Consensus ; Neoplasm Staging ; Lymphoma, Non-Hodgkin/diagnostic imaging ; Lymphoma, Non-Hodgkin/pathology ; Lymphoma/pathology ; Fluorodeoxyglucose F18
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2022-07-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80272-4
    ISSN 1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
    ISSN (online) 1535-5667
    ISSN 0097-9058 ; 0161-5505 ; 0022-3123
    DOI 10.2967/jnumed.122.264106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 114: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 328: Show issues

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  3. Article ; Online: Application of the Lugano Classification for Initial Evaluation, Staging, and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma: The PRoLoG Consensus Initiative (Part 2-Technical).

    Ricard, Fabien / Barrington, Sally / Korn, Ron / Brueggenwerth, Guenther / Trotman, Judith / Cheson, Bruce / Salles, Gilles / Schwartz, Larry / Goldmacher, Greg / Jarecha, Rudresh / Narang, Jayant / Broussais, Florence / Galette, Paul / Liu, Min / Bajpai, Surabhi / Perlman, Eric / Gillis, Julie / Smalberg, Ira / Terve, Pierre /
    Zahlmann, Gudrun / Schmid, Annette

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    2022  Volume 64, Issue 2, Page(s) 239–243

    Abstract: The aim of this initiative was to provide consensus recommendations from a consortium of academic and industry experts in the field of lymphoma and imaging for the consistent application of imaging assessment with the Lugano classification. ...

    Abstract The aim of this initiative was to provide consensus recommendations from a consortium of academic and industry experts in the field of lymphoma and imaging for the consistent application of imaging assessment with the Lugano classification.
    MeSH term(s) Humans ; Positron Emission Tomography Computed Tomography ; Consensus ; Neoplasm Staging ; Lymphoma, Non-Hodgkin/diagnostic imaging ; Lymphoma, Non-Hodgkin/pathology ; Lymphoma/pathology ; Fluorodeoxyglucose F18
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2022-07-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80272-4
    ISSN 1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
    ISSN (online) 1535-5667
    ISSN 0097-9058 ; 0161-5505 ; 0022-3123
    DOI 10.2967/jnumed.122.264124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 114: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 328: Show issues

    Order via subito

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  4. Article ; Online: CT cerebral blood flow maps optimally correlate with admission diffusion-weighted imaging in acute stroke but thresholds vary by postprocessing platform.

    Kamalian, Shahmir / Kamalian, Shervin / Maas, Matthew B / Goldmacher, Greg V / Payabvash, Seyedmehdi / Akbar, Adnan / Schaefer, Pamela W / Furie, Karen L / Gonzalez, R Gilberto / Lev, Michael H

    Stroke

    2011  Volume 42, Issue 7, Page(s) 1923–1928

    Abstract: Background and purpose: Admission infarct core lesion size is an important determinant of management and outcome in acute (<9 hours) stroke. Our purposes were to: (1) determine the optimal CT perfusion parameter to define infarct core using various ... ...

    Abstract Background and purpose: Admission infarct core lesion size is an important determinant of management and outcome in acute (<9 hours) stroke. Our purposes were to: (1) determine the optimal CT perfusion parameter to define infarct core using various postprocessing platforms; and (2) establish the degree of variability in threshold values between these different platforms.
    Methods: We evaluated 48 consecutive cases with vessel occlusion and admission CT perfusion and diffusion-weighted imaging within 3 hours of each other. CT perfusion was acquired with a "second-generation" 66-second biphasic cine protocol and postprocessed using "standard" (from 2 vendors, "A-std" and "B-std") and "delay-corrected" (from 1 vendor, "A-dc") commercial software. Receiver operating characteristic curve analysis was performed comparing each CT perfusion parameter-both absolute and normalized to the contralateral uninvolved hemisphere-between infarcted and noninfarcted regions as defined by coregistered diffusion-weighted imaging.
    Results: Cerebral blood flow had the highest accuracy (receiver operating characteristic area under the curve) for all 3 platforms (P<0.01). The maximal areas under the curve for each parameter were: absolute cerebral blood flow 0.88, cerebral blood volume 0.81, and mean transit time 0.82 and relative Cerebral blood flow 0.88, cerebral blood volume 0.83, and mean transit time 0.82. Optimal receiver operating characteristic operating point thresholds varied significantly between different platforms (Friedman test, P<0.01).
    Conclusions: Admission absolute and normalized "second-generation" cine acquired CT cerebral blood flow lesion volumes correlate more closely with diffusion-weighted imaging-defined infarct core than do those of CT cerebral blood volume or mean transit time. Although limited availability of diffusion-weighted imaging for some patients creates impetus to develop alternative methods of estimating core, the marked variability in quantification among different postprocessing software limits generalizability of parameter map thresholds between platforms.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Area Under Curve ; Brain Ischemia/pathology ; Cerebrovascular Circulation ; Diffusion ; Female ; Humans ; Image Processing, Computer-Assisted/methods ; Male ; Middle Aged ; Perfusion ; ROC Curve ; Reproducibility of Results ; Stroke/pathology ; Time Factors ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2011-05-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.110.610618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 448: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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