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  1. Book ; Online ; E-Book: Immortal

    Goldman, David

    our cells, DNA, and bodies

    2021  

    Author's details David Goldman
    Keywords DNA/Physiological transport ; Aging/Molecular aspects
    Subject code 572.86
    Language English
    Size 1 online resource :, illustrations (some color)
    Publisher Academic Press
    Publishing place London
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-323-85693-4 ; 0-323-85692-6 ; 978-0-323-85692-8 ; 978-0-323-85693-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Book: Our genes, our choices

    Goldman, David

    how genotype and gene interactions affect behavior

    2012  

    Author's details David Goldman
    Keywords Behavior genetics ; Neurogenetics ; Verhaltensgenetik
    Language English
    Size XVII, 254 S. : Ill., graph. Darst., 23 cm
    Edition 1. ed.
    Publisher Elsevier, Acad. Press
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT017225558
    ISBN 978-0-12-396952-1 ; 0-12-396952-2
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2012 A 2024 order for loan Magazin

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  3. Article ; Online: Predicting Suicide.

    Goldman, David

    The American journal of psychiatry

    2020  Volume 177, Issue 10, Page(s) 881–883

    MeSH term(s) Genome-Wide Association Study ; Humans ; Suicidal Ideation ; Suicide
    Language English
    Publishing date 2020-09-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.2020.20071138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Genetic Influences on Fetal Alcohol Spectrum Disorder.

    Sambo, Danielle / Goldman, David

    Genes

    2023  Volume 14, Issue 1

    Abstract: Fetal alcohol spectrum disorder (FASD) encompasses the range of deleterious outcomes of prenatal alcohol exposure (PAE) in the affected offspring, including developmental delay, intellectual disability, attention deficits, and conduct disorders. Several ... ...

    Abstract Fetal alcohol spectrum disorder (FASD) encompasses the range of deleterious outcomes of prenatal alcohol exposure (PAE) in the affected offspring, including developmental delay, intellectual disability, attention deficits, and conduct disorders. Several factors contribute to the risk for and severity of FASD, including the timing, dose, and duration of PAE and maternal factors such as age and nutrition. Although poorly understood, genetic factors also contribute to the expression of FASD, with studies in both humans and animal models revealing genetic influences on susceptibility. In this article, we review the literature related to the genetics of FASD in humans, including twin studies, candidate gene studies in different populations, and genetic testing identifying copy number variants. Overall, these studies suggest different genetic factors, both in the mother and in the offspring, influence the phenotypic outcomes of PAE. While further work is needed, understanding how genetic factors influence FASD will provide insight into the mechanisms contributing to alcohol teratogenicity and FASD risk and ultimately may lead to means for early detection and intervention.
    MeSH term(s) Animals ; Humans ; Female ; Pregnancy ; Fetal Alcohol Spectrum Disorders/genetics ; Fetal Alcohol Spectrum Disorders/diagnosis ; Fetal Alcohol Spectrum Disorders/metabolism ; Prenatal Exposure Delayed Effects/genetics ; Mothers ; Ethanol/toxicity ; Models, Animal
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Intramural
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes14010195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Aldehyde Dehydrogenase Deficiency as Cause of Facial Flushing Reaction to Alcohol in Japanese.

    Goldman, David

    Alcohol health and research world

    2019  Volume 19, Issue 1, Page(s) 48–49

    Language English
    Publishing date 2019-12-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 427760-0
    ISSN 0090-838X
    ISSN 0090-838X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  6. Article ; Online: Predicting Depression.

    Goldman, David

    The American journal of psychiatry

    2019  Volume 176, Issue 8, Page(s) 598–599

    MeSH term(s) Adolescent ; Depression ; Depressive Disorder ; Humans ; Multifactorial Inheritance
    Language English
    Publishing date 2019-07-31
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.2019.19060590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Ting-Kai Li, M.D.

    Goldman, David

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2019  Volume 44, Issue 6, Page(s) 1176

    Language English
    Publishing date 2019-03-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-019-0358-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2379: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Completely Plant-Based Diets That Meet Energy Requirements for Resistance Training Can Supply Enough Protein and Leucine to Maximize Hypertrophy and Strength in Male Bodybuilders: A Modeling Study.

    Goldman, David M / Warbeck, Cassandra B / Karlsen, Micaela C

    Nutrients

    2024  Volume 16, Issue 8

    Abstract: Despite increasing awareness of plant-based diets for health and athletic performance, athletes are cautioned that careful dietary monitoring is necessary. Whether commonly consumed plant-based diets are nutritionally adequate for maximal muscular ... ...

    Abstract Despite increasing awareness of plant-based diets for health and athletic performance, athletes are cautioned that careful dietary monitoring is necessary. Whether commonly consumed plant-based diets are nutritionally adequate for maximal muscular hypertrophy remains unknown. This modeling study assessed the nutrient composition of completely plant-based diets scaled to the caloric demands of maximal muscle mass and strength development in adult male bodybuilders. To model calorie requirements, anthropometric data from bodybuilders were input into the Tinsley resting metabolic rate prediction equation, and an appropriate physical activity factor and calorie surplus were applied. Dietary data from a large cohort following completely plant-based diets were then scaled to meet these needs. Modeled intakes for nutrients of interest were calculated as 1.8 g/kg/day of protein and 2.75 g/meal of leucine, which surpass mean requirements for maximal increases in muscle mass and strength and muscle protein synthesis, respectively. Daily levels for all micronutrients, except vitamin D, also exceeded requirements. Saturated fat levels were aligned with dietary guidelines, although sodium levels exceeded recommended limits. Consumption of larger portions of commonplace plant-based diets, scaled to meet the energy demands of maximal accrual of muscle mass and strength, satisfied protein and leucine requirements without the need for additional planning.
    MeSH term(s) Humans ; Male ; Dietary Proteins/administration & dosage ; Leucine/administration & dosage ; Muscle Strength/physiology ; Adult ; Energy Intake ; Resistance Training ; Muscle, Skeletal/metabolism ; Nutritional Requirements ; Diet, Vegetarian ; Young Adult ; Hypertrophy ; Weight Lifting/physiology ; Diet, Plant-Based
    Chemical Substances Dietary Proteins ; Leucine (GMW67QNF9C)
    Language English
    Publishing date 2024-04-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16081122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Genetic Influences on Fetal Alcohol Spectrum Disorder

    Sambo, Danielle / Goldman, David

    Genes (Basel). 2023 Jan. 12, v. 14, no. 1

    2023  

    Abstract: Fetal alcohol spectrum disorder (FASD) encompasses the range of deleterious outcomes of prenatal alcohol exposure (PAE) in the affected offspring, including developmental delay, intellectual disability, attention deficits, and conduct disorders. Several ... ...

    Abstract Fetal alcohol spectrum disorder (FASD) encompasses the range of deleterious outcomes of prenatal alcohol exposure (PAE) in the affected offspring, including developmental delay, intellectual disability, attention deficits, and conduct disorders. Several factors contribute to the risk for and severity of FASD, including the timing, dose, and duration of PAE and maternal factors such as age and nutrition. Although poorly understood, genetic factors also contribute to the expression of FASD, with studies in both humans and animal models revealing genetic influences on susceptibility. In this article, we review the literature related to the genetics of FASD in humans, including twin studies, candidate gene studies in different populations, and genetic testing identifying copy number variants. Overall, these studies suggest different genetic factors, both in the mother and in the offspring, influence the phenotypic outcomes of PAE. While further work is needed, understanding how genetic factors influence FASD will provide insight into the mechanisms contributing to alcohol teratogenicity and FASD risk and ultimately may lead to means for early detection and intervention.
    Keywords alcohols ; animals ; fetal alcohol syndrome ; genes ; nutrition ; phenotype ; progeny ; risk ; teratogenicity
    Language English
    Dates of publication 2023-0112
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2527218-4
    ISSN 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes14010195
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: The Other Side of the Coin: Anti-inflammatory Antibody Therapy for Infectious Diseases.

    Goldman, David L

    Infection and immunity

    2020  Volume 88, Issue 2

    Abstract: The inflammatory response to the ... ...

    Abstract The inflammatory response to the fungus
    MeSH term(s) Anti-Inflammatory Agents ; Humans ; Immunotherapy ; Pneumocystis ; Pneumonia, Pneumocystis ; Sulfasalazine
    Chemical Substances Anti-Inflammatory Agents ; Sulfasalazine (3XC8GUZ6CB)
    Language English
    Publishing date 2020-01-22
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/IAI.00844-19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 684: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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