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  1. Article: Post-COVID-19 Cognitive Decline and Apoe Polymorphism: Towards a Possible Link?

    Tavares-Júnior, José Wagner Leonel / Oliveira, Danilo Nunes / da Silva, Jean Breno Silveira / Queiroz Feitosa, Werbety Lucas / Sousa, Artur Victor Menezes / Marinho, Samuel Cavalcante / Cunha, Letícia Chaves Vieira / Gaspar, Safira de Brito / Gomes, Carmem Meyve Pereira / de Oliveira, Laís Lacerda Brasil / Moreira-Nunes, Caroline Aquino / Sobreira, Emmanuelle Silva Tavares / Moraes, Maria Elisabete Amaral de / Sobreira-Neto, Manoel Alves / Montenegro, Raquel Carvalho / Braga-Neto, Pedro

    Brain sciences

    2023  Volume 13, Issue 12

    Abstract: ... ...

    Abstract APOE
    Language English
    Publishing date 2023-11-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13121611
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Long-covid cognitive impairment: Cognitive assessment and apolipoprotein E (APOE) genotyping correlation in a Brazilian cohort.

    Tavares-Júnior, José Wagner Leonel / Oliveira, Danilo Nunes / da Silva, Jean Breno Silveira / Feitosa, Werbety Lucas Queiroz / Sousa, Artur Victor Menezes / Cunha, Letícia Chaves Vieira / Gaspar, Safira de Brito / Gomes, Carmem Meyve Pereira / de Oliveira, Laís Lacerda Brasil / Moreira-Nunes, Caroline Aquino / Montenegro, Raquel Carvalho / Sobreira-Neto, Manoel Alves / Braga-Neto, Pedro

    Frontiers in psychiatry

    2022  Volume 13, Page(s) 947583

    Abstract: Introduction: Few studies have objectively evaluated cognitive deficits after the acute phase of COVID-19 disease. Moreover, the role of apolipoprotein E (APOE) genotypes in cognitive decline in patients with COVID-19 has not been evaluated yet.: ... ...

    Abstract Introduction: Few studies have objectively evaluated cognitive deficits after the acute phase of COVID-19 disease. Moreover, the role of apolipoprotein E (APOE) genotypes in cognitive decline in patients with COVID-19 has not been evaluated yet.
    Methods: This cross-sectional study was conducted in confirmed cases of COVID-19 patients with neurological symptoms that persisted for more than 3 months from the onset. We determined APOE genotypes.
    Results: The final sample consisted of 141 patients. The most frequent APOE genotype was E3/E3 (
    Discussion: Hospitalized patients had more severe infection with a greater possibility of systemic complications, greater inflammatory response, and prolonged hospitalization, which could impact cognitive performance. Cognitive impairment in patients with COVID-19 does not necessarily involve specific APOE polymorphisms. However, psychiatric disorders may also be responsible for cognitive complaints. Cognitive complaints are frequent in patients with COVID-19, even after the acute phase of the disease and in mild cases. Hospitalized participants and depressed patients may have a higher risk of cognitive impairment. APOE genotypes or haplotypes may not significantly play a role in COVID-19 cognitive impairment.
    Language English
    Publishing date 2022-08-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2022.947583
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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