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  1. Article ; Online: Neuroanatomical characterization of the G protein-coupled receptor activity evoked by galanin-related ligands.

    Barreda-Gómez, G / Manuel, I / Rodríguez-Puertas, R

    Journal of chemical neuroanatomy

    2022  Volume 128, Page(s) 102226

    Abstract: Galanin neuropeptide is distributed throughout the mammalian nervous system modulating a plethora of diverse physiological functions, including nociception, cognition and neuroendocrine regulation. The regulation of the galaninergic system is an ... ...

    Abstract Galanin neuropeptide is distributed throughout the mammalian nervous system modulating a plethora of diverse physiological functions, including nociception, cognition and neuroendocrine regulation. The regulation of the galaninergic system is an interesting approach for the treatment of different diseases associated to those systems. Nevertheless, the pharmacological selectivity and activities of some galanin receptor (GalR) ligands are still in discussion and seem to depend on the dose, the receptor subtype and the second messengers to which they are coupled at different brain areas. The activity of different GalR ligands on G
    MeSH term(s) Rats ; Animals ; Galanin/metabolism ; Receptors, Galanin/metabolism ; Ligands ; Guanosine 5'-O-(3-Thiotriphosphate)/metabolism ; Guanosine 5'-O-(3-Thiotriphosphate)/pharmacology ; Brain/metabolism ; Peptide Hormones/metabolism ; Mammals
    Chemical Substances Galanin (88813-36-9) ; Receptors, Galanin ; Ligands ; Guanosine 5'-O-(3-Thiotriphosphate) (37589-80-3) ; Peptide Hormones
    Language English
    Publishing date 2022-12-23
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639443-7
    ISSN 1873-6300 ; 0891-0618
    ISSN (online) 1873-6300
    ISSN 0891-0618
    DOI 10.1016/j.jchemneu.2022.102226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Current Strategies to Inhibit High Affinity FcεRI-Mediated Signaling for the Treatment of Allergic Disease.

    Gomez, Gregorio

    Frontiers in immunology

    2019  Volume 10, Page(s) 175

    Abstract: Allergies and asthma are a major cause of chronic disease whose prevalence has been on the rise. Allergic disease including seasonal rhinitis, atopic dermatitis, urticaria, anaphylaxis, and asthma, are associated with activation of tissue-resident mast ... ...

    Abstract Allergies and asthma are a major cause of chronic disease whose prevalence has been on the rise. Allergic disease including seasonal rhinitis, atopic dermatitis, urticaria, anaphylaxis, and asthma, are associated with activation of tissue-resident mast cells and circulating basophils. Although these cells can be activated in different ways, allergic reactions are normally associated with the crosslinking of the high affinity Fc receptor for Immunoglobulin E, FcεRI, with multivalent antigen. Inflammatory mediators released from cytoplasmic granules, or biosynthesized
    MeSH term(s) Animals ; Anti-Allergic Agents/pharmacology ; Anti-Allergic Agents/therapeutic use ; Basophils/drug effects ; Basophils/immunology ; Basophils/metabolism ; Humans ; Hypersensitivity/drug therapy ; Hypersensitivity/immunology ; Hypersensitivity/metabolism ; Immunoglobulin E/immunology ; Mast Cells/drug effects ; Mast Cells/immunology ; Mast Cells/metabolism ; Muscle Proteins/chemistry ; Muscle Proteins/metabolism ; Nuclear Proteins/chemistry ; Nuclear Proteins/metabolism ; Omalizumab/pharmacology ; Omalizumab/therapeutic use ; Protein Binding ; Protein Interaction Domains and Motifs ; Receptors, IgE/metabolism ; Signal Transduction
    Chemical Substances ANKRD23 protein, human ; Anti-Allergic Agents ; Muscle Proteins ; Nuclear Proteins ; Receptors, IgE ; Omalizumab (2P471X1Z11) ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2019-02-07
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2019.00175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Spatial variation in the intensity of interactions via heterospecific pollen transfer may contribute to local and global patterns of plant diversity.

    Arceo-Gómez, Gerardo

    Annals of botany

    2021  Volume 128, Issue 4, Page(s) 383–394

    Abstract: Background: Studies that aim to understand the processes that generate and organize plant diversity in nature have a long history in ecology. Among these, the study of plant-plant interactions that take place indirectly via pollinator choice and floral ... ...

    Abstract Background: Studies that aim to understand the processes that generate and organize plant diversity in nature have a long history in ecology. Among these, the study of plant-plant interactions that take place indirectly via pollinator choice and floral visitation has been paramount. Current evidence, however, indicates that plants can interact more directly via heterospecific pollen (HP) transfer and that these interactions are ubiquitous and can have strong fitness effects. The intensity of HP interactions can also vary spatially, with important implications for floral evolution and community assembly.
    Scope: Interest in understanding the role of heterospecific pollen transfer in the diversification and organization of plant communities is rapidly rising. The existence of spatial variation in the intensity of species interactions and their role in shaping patterns of diversity is also well recognized. However, after 40 years of research, the importance of spatial variation in HP transfer intensity and effects remains poorly known, and thus we have ignored its potential in shaping patterns of diversity at local and global scales. Here, I develop a conceptual framework and summarize existing evidence for the ecological and evolutionary consequences of spatial variation in HP transfer interactions and outline future directions in this field.
    Conclusions: The drivers of variation in HP transfer discussed here illustrate the high potential for geographic variation in HP intensity and its effects, as well as in the evolutionary responses to HP receipt. So far, the study of pollinator-mediated plant-plant interactions has been almost entirely dominated by studies of pre-pollination interactions even though their outcomes can be influenced by plant-plant interactions that take place on the stigma. It is hence critical that we fully evaluate the consequences and context-dependency of HP transfer interactions in order to gain a more complete understanding of the role that plant-pollinator interactions play in generating and organizing plant biodiversity.
    MeSH term(s) Biodiversity ; Flowers ; Plants ; Pollen ; Pollination
    Language English
    Publishing date 2021-05-06
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1461328-1
    ISSN 1095-8290 ; 0305-7364
    ISSN (online) 1095-8290
    ISSN 0305-7364
    DOI 10.1093/aob/mcab082
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  4. Article ; Online: Primary Cultures of Olfactory Neurons from the Avian Olfactory Epithelium.

    Gomez, George

    Methods in molecular biology (Clifton, N.J.)

    2018  Volume 1817, Page(s) 197–207

    Abstract: The culture of the olfactory epithelium has been a useful model for the study of neurogenesis since olfactory neurons regenerate continuously throughout the adult lifespan. Structurally and functionally mature olfactory neurons are generated in vitro ... ...

    Abstract The culture of the olfactory epithelium has been a useful model for the study of neurogenesis since olfactory neurons regenerate continuously throughout the adult lifespan. Structurally and functionally mature olfactory neurons are generated in vitro from non-neuronal precursors in a process that resembles the in vivo counterparts. This chapter describes a technique for culture of olfactory neurons from the avian olfactory epithelium of embryonic chickens; this enables the controlled laboratory study of a critical sensory system that is unstudied in this major vertebrate class. The techniques described here are broadly applicable to other endothermic vertebrate species.
    MeSH term(s) Animals ; Cell Differentiation ; Cells, Cultured ; Chickens ; Neurogenesis ; Neurons/cytology ; Olfactory Mucosa/cytology ; Olfactory Mucosa/embryology ; Primary Cell Culture/methods
    Language English
    Publishing date 2018-07-19
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-4939-8600-2_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Neonatal listeriosis: a rare but not-to-be forgotten infection.

    Gomez, Gretell / Islam, Shamim

    BMJ case reports

    2022  Volume 15, Issue 5

    Abstract: ... Listeria ... ...

    Abstract Listeria monocytogenes
    MeSH term(s) Cheese ; Disease Outbreaks ; Female ; Fetal Diseases ; Food Microbiology ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases ; Listeria monocytogenes ; Listeriosis/diagnosis ; Listeriosis/drug therapy ; Pregnancy
    Language English
    Publishing date 2022-05-06
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-243033
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  6. Article ; Online: Responses of intraspecific metabolic scaling to temperature and activity differ between water- and air-breathing ectothermic vertebrates.

    García-Gómez, Guillermo / Hirst, Andrew G / Spencer, Matthew / Atkinson, David

    Ecology letters

    2024  Volume 27, Issue 2, Page(s) e14389

    Abstract: Metabolism underpins all life-sustaining processes and varies profoundly with body size, temperature and locomotor activity. A current theory explains some of the size-dependence of metabolic rate (its mass exponent, b) through changes in metabolic level ...

    Abstract Metabolism underpins all life-sustaining processes and varies profoundly with body size, temperature and locomotor activity. A current theory explains some of the size-dependence of metabolic rate (its mass exponent, b) through changes in metabolic level (L). We propose two predictive advances that: (a) combine the above theory with the evolved avoidance of oxygen limitation in water-breathers experiencing warming, and (b) quantify the overall magnitude of combined temperatures and degrees of locomotion on metabolic scaling across air- and water-breathers. We use intraspecific metabolic scaling responses to temperature (523 regressions) and activity (281 regressions) in diverse ectothermic vertebrates (fish, reptiles and amphibians) to show that b decreases with temperature-increased L in water-breathers, supporting surface area-related avoidance of oxygen limitation, whereas b increases with activity-increased L in air-breathers, following volume-related influences. This new theoretical integration quantitatively incorporates different influences (warming, locomotion) and respiration modes (aquatic, terrestrial) on animal energetics.
    MeSH term(s) Animals ; Temperature ; Vertebrates ; Body Size ; Fishes ; Oxygen/physiology
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1441608-6
    ISSN 1461-0248 ; 1461-023X
    ISSN (online) 1461-0248
    ISSN 1461-023X
    DOI 10.1111/ele.14389
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  7. Article ; Online: The Tropical Gothic and Beyond

    Felipe Gómez G.

    eTropic: electronic journal of studies in the tropics, Vol 18, Iss

    El Grupo de Cali’s Legacies for Contemporary Latin American Literature, Cinema, and Culture

    2019  Volume 1

    Abstract: The creation and development of a tropical gothic is arguably the most important legacy of El Grupo de Cali, an interdisciplinary collective led by writer and film critic Andrés Caicedo Estela, and filmmakers Carlos Mayolo and Luis Ospina, during the ... ...

    Abstract The creation and development of a tropical gothic is arguably the most important legacy of El Grupo de Cali, an interdisciplinary collective led by writer and film critic Andrés Caicedo Estela, and filmmakers Carlos Mayolo and Luis Ospina, during the 1970s in Colombia. In El Grupo’s tropical gothic, the conventions of the literary and cinematic gothic undergo a process of transculturation and tropicalization. With this transformation, Caicedo, Mayolo and Ospina postulate a dark reality that is urban and violent, and in which youth have protagonist roles both as agents and victims of violence. The revival of the monster within this tropical gothic reveals itself as intrinsically linked not only to the influence of cinematic tropes such as Hollywood B-series vampire films, but also to the connections between local myths and legends and forms of structural violence rooted in socioeconomic, political, racial and sexual oppression. Beyond the development of a tropical gothic aesthetic, the innovations of Caicedo’s literary writing include the insistence in locating youthful characters in urban, countercultural scenarios defined by elements of popular culture such as film, popular music, or drugs. These characteristics effectively locate his writings on the flip side of magical realism and act as complements to the Grupo’s tropical gothic in their efforts to narrate the experience of the modern tropical Latin American city.
    Keywords tropical gothic ; grupo de cali ; colombia ; literary ; cinema ; urban ; violent ; Social Sciences ; H
    Subject code 820
    Language English
    Publishing date 2019-05-01T00:00:00Z
    Publisher James Cook University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The Tropical Gothic and Beyond

    Felipe Gómez G.

    eTropic: electronic journal of studies in the tropics, Vol 18, Iss

    El Grupo de Cali’s Legacies for Contemporary Latin American Literature, Cinema, and Culture

    2019  Volume 1

    Abstract: The creation and development of a tropical gothic is arguably the most important legacy of El Grupo de Cali, an interdisciplinary collective led by writer and film critic Andrés Caicedo Estela, and filmmakers Carlos Mayolo and Luis Ospina, during the ... ...

    Abstract The creation and development of a tropical gothic is arguably the most important legacy of El Grupo de Cali, an interdisciplinary collective led by writer and film critic Andrés Caicedo Estela, and filmmakers Carlos Mayolo and Luis Ospina, during the 1970s in Colombia. In El Grupo’s tropical gothic, the conventions of the literary and cinematic gothic undergo a process of transculturation and tropicalization. With this transformation, Caicedo, Mayolo and Ospina postulate a dark reality that is urban and violent, and in which youth have protagonist roles both as agents and victims of violence. The revival of the monster within this tropical gothic reveals itself as intrinsically linked not only to the influence of cinematic tropes such as Hollywood B-series vampire films, but also to the connections between local myths and legends and forms of structural violence rooted in socioeconomic, political, racial and sexual oppression. Beyond the development of a tropical gothic aesthetic, the innovations of Caicedo’s literary writing include the insistence in locating youthful characters in urban, countercultural scenarios defined by elements of popular culture such as film, popular music, or drugs. These characteristics effectively locate his writings on the flip side of magical realism and act as complements to the Grupo’s tropical gothic in their efforts to narrate the experience of the modern tropical Latin American city.
    Keywords tropical gothic ; Grupo de Cali ; Caicedo Estela ; Andrés ; Mayolo ; Carlos; Ospina ; Social Sciences ; H
    Subject code 820
    Language English
    Publishing date 2019-05-01T00:00:00Z
    Publisher James Cook University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Exploring self-regulation theory as a mechanism of the effects of psychological contract fulfillment: The role of emotional intelligence.

    Laulié, Lyonel / Briceño-Jiménez, Gabriel / Henríquez-Gómez, Gisselle

    Frontiers in psychology

    2023  Volume 14, Page(s) 1090094

    Abstract: As self-regulation theory has increasingly been used as a theoretical lens to explain the effects of psychological contract evaluations and employee outcomes, we test whether emotional intelligence (an ability for self-regulation) is a potential ... ...

    Abstract As self-regulation theory has increasingly been used as a theoretical lens to explain the effects of psychological contract evaluations and employee outcomes, we test whether emotional intelligence (an ability for self-regulation) is a potential moderator of these relationships. More concretely, using a multiple times survey design in an education-based organization with 247 participants, we examined whether emotional intelligence moderates the mediation effect of emotional exhaustion on the relationship between psychological contract fulfillment and turnover intentions. Using a structural equations model (SEM) framework, our results support our hypotheses that individuals with low emotional intelligence do not experience the benefits of having fulfilled psychological contracts. Psychological contract fulfillment significantly reduces the likelihood of emotional exhaustion but only for individuals with high emotional intelligence. Consequently, turnover intentions are lower for emotionally intelligent individuals who experience the fulfillment of psychological contracts. Theoretical and practical implications are discussed. We conclude our study by suggesting that emotional intelligence should be considered as a relevant individual difference in future psychological contract research.
    Language English
    Publishing date 2023-03-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1090094
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  10. Article: Combined Phacoemulsification and STREAMLINE Surgical System Canal of Schlemm Transluminal Dilation in Eyes of Hispanic Patients with Mild to Moderate Glaucoma.

    Lazcano-Gomez, Gabriel / Antzoulatos, George Luis / Kahook, Malik Y

    Clinical ophthalmology (Auckland, N.Z.)

    2023  Volume 17, Page(s) 1911–1918

    Abstract: Purpose: To characterize clinical outcomes of transluminal dilation of the canal of Schlemm using the STREAMLINE Surgical System combined with phacoemulsification in eyes of Hispanic patients diagnosed with mild to moderate primary open-angle glaucoma.!# ...

    Abstract Purpose: To characterize clinical outcomes of transluminal dilation of the canal of Schlemm using the STREAMLINE Surgical System combined with phacoemulsification in eyes of Hispanic patients diagnosed with mild to moderate primary open-angle glaucoma.
    Methods: This was a prospective analysis of all cases performed and followed up to 12 months. All eyes underwent medication washout preoperatively. Reduction in intraocular pressure (IOP) from unmedicated baseline, as well as medications from pre-washout baseline, were analyzed at postoperative Day 1, Week 1, and Months 1, 3, 6, 9, and 12.
    Results: All 37 patients were Hispanic, 83.8% were female, and mean (standard deviation) age was 66.0 (10.5) years. Mean medicated preoperative IOP was 16.9 (3.2) mmHg using a mean of 2.1 (0.9) medications, unmedicated baseline IOP (after washout) was 23.2 (2.3) mmHg, and mean IOP at every postoperative study visit was significantly lower (p<0.0002). Mean IOP from month 1 through the first postoperative year ranged from 14.7-16.2 mmHg, representing a reduction of 7.0-8.5 mmHg (30.7-36.5%). At month 12, 80% of all eyes (28/35) and 77.8% of medication-free eyes (14/18) had IOP reduction ≥20% from unmedicated baseline, and 51.4% of eyes (18/35) were medication-free. Mean medication use was significantly reduced (by 59.9-74.6%, p<0.0001) at every postoperative study visit. The only adverse event occurring in >1 eye was high IOP (n=4) which was responsive to topical medical therapy; no adverse events were attributed to the transluminal dilation procedure.
    Conclusion: Transluminal dilation of the canal of Schlemm using the STREAMLINE Surgical System combined with phacoemulsification safely and effectively reduced both IOP and dependence on IOP-lowering medications in a Hispanic population diagnosed with POAG and should be considered at the time of phacoemulsification in Hispanic patients who have a need for IOP reduction, medication reduction, or both.
    Language English
    Publishing date 2023-07-04
    Publishing country New Zealand
    Document type Case Reports ; Clinical Trial
    ISSN 1177-5467
    ISSN 1177-5467
    DOI 10.2147/OPTH.S409164
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