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Book ; Online: Separation, Extraction and Purification of Natural Products from Plants

Gong, Xingchu

2023

Keywords	Research & information: general ; Chemistry ; Analytical chemistry ; azide ; cilostazol ; COVID-19 ; genotoxic impurity ; validation ; LLE ; ethanol precipitation ; loss of active ingredients ; mixing condition indicator ; micromesh mixer ; Caulis sinomenii ; microfiltration ; ultrafiltration ; sinomenine hydrochloride ; separation and purification ; Phyllanthus urinaria L. ; ellagic acid ; mechanochemical-assisted extraction ; macroporous adsorption resin ; compositional monosaccharides ; HPLC-ELSD/PDA combined with HPSEC-MALLS-RID ; molecular weight ; quality markers (Q-marker) ; red ginseng polysaccharides ; Xiaochaihu (XCH) formula ; preparations ; quality control ; standard ; 4-aryl-3,4-dihydropyrimidin-2(1H)-ones ; teicoplanin aglycone ; chiral HPLC ; enantioselectivity ; molecular docking ; molecular dynamics ; Radix Angelicae sinensis ; volatile oil ; Box-Behnken design ; steam distillation ; extraction kinetics ; design space ; dill ; Anethum graveolens L. ; essential oil ; Neofusicoccum parvum ; antifungal mechanism ; near-infrared spectroscopy ; Astragali radix ; alcohol precipitation ; accuracy profile ; Vis-NIR spectroscopy ; Ginkgo biloba L. leaves ; in-line analysis ; column chromatographic elution ; consistency evaluation ; multivariate statistical process control (MSPC) ; quality by design ; Xiaochaihu capsule ; quantitative chromatographic fingerprint ; definitive screening design ; Plackett-Burman ; Forsythia suspensa ; Lonicera japonica
Language	English
Size	1 electronic resource (198 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030649860
ISBN	9783036590158 ; 3036590153
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Thesis: Water and nitrogen co-limitation of plant primary production in a semiarid grassland of Inner Mongolia

Gong, Xiaoying

(Schriftenreihe des Instituts für Pflanzenbau und Pflanzenzüchtung, Christian-Albrechts-Universität zu Kiel ; 68)

2010

Author's details	Xiaoying Gong
Series title	Schriftenreihe des Instituts für Pflanzenbau und Pflanzenzüchtung, Christian-Albrechts-Universität zu Kiel ; 68
Collection
Language	English
Size	IV, 127 S. : graph. Darst., Kt.
Publisher	Inst. für Pflanzenbau und Pflanzenzüchtung, Grünland und Futterbau/Ökologischer Landbau
Publishing place	Kiel
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Kiel, Univ., Diss., 2010
Note	Enth. Zeitschriftenaufsätze ; Zsfassung in dt. Sprache
HBZ-ID	HT016444875
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

In stock of ZB MED Bonn / Germany

Shelf mark	Loan status	Location
108/874	available for loan (reading room)	Freihandmagazin (U1)

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Article ; Online: Digital transformation and innovation output of manufacturing companies-An analysis of the mediating role of internal and external transaction costs.

Meng, Xiangpeng / Gong, Xinshu

PloS one

2024 Volume 19, Issue 1, Page(s) e0296876

Abstract: Digital transformation, based on digital technologies, has triggered economic growth in many industries and brought about production and service transformation in the manufacturing sector. As an important source of innovation output and a driving force ... ...

Abstract	Digital transformation, based on digital technologies, has triggered economic growth in many industries and brought about production and service transformation in the manufacturing sector. As an important source of innovation output and a driving force for national economic development, it is of great significance to study the impact of digital transformation on innovation output in manufacturing companies. This study analyzes the effects of digital transformation on the quality, quantity, and overall innovation output of manufacturing companies from both the macro provincial-level digital transformation and micro enterprise-level digital transformation perspectives. Additionally, using data from manufacturing companies listed on the Shanghai and Shenzhen stock exchanges from 2012 to 2022, this study empirically tests the mechanism through which digital transformation affects innovation output from the perspectives of internal transaction costs and external transaction costs. The results show that digital transformation promotes overall improvement in innovation output of manufacturing companies and leads to improvements in both the quality and quantity of innovation output. Furthermore, the study finds that the effect of digital transformation on innovation output has a nonlinear characteristic under different levels of market competitiveness and market freedom. The mediation analysis reveals that the influence of digital transformation on innovation output can be attributed to the reduction of internal transaction costs and the enhancement of external transaction efficiency. In terms of digital policy formulation, it is necessary to coordinate the development of diverse and innovative digital infrastructure at the macro level with the micro-level ecosystems of enterprises, in order to reduce transaction costs within and outside innovative entities. Ultimately, it is essential for the government to foster a conducive free market environment that enhances transaction efficiency and timely regulates the excessive competition resulting from oligopolistic monopolies, thus maximizing the potential of digital transformation in promoting innovation output.
MeSH term(s)	Ecosystem ; China ; Commerce ; Industry ; Digital Technology
Language	English
Publishing date	2024-01-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0296876
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Childhood Maltreatment and Non-Suicidal Self-Injury in Adolescents: Testing a Moderated Mediating Model.

Gong, Xue / Zhang, Lulu

Journal of interpersonal violence

2024 Volume 39, Issue 5-6, Page(s) 925–948

Abstract: There is a wealth of evidence to suggest that childhood maltreatment is a major risk factor contributing to non-suicidal self-injury (NSSI) among adolescents. However, how and under what conditions childhood maltreatment is related to NSSI remains ... ...

Abstract	There is a wealth of evidence to suggest that childhood maltreatment is a major risk factor contributing to non-suicidal self-injury (NSSI) among adolescents. However, how and under what conditions childhood maltreatment is related to NSSI remains largely unclear. This study examined the indirect effect of depressive symptoms in the relation between childhood maltreatment and non-suicidal self-injury, as well as the moderating role of cognitive reappraisal and emotion reactivity in those associations. A sample of 1,984 Chinese adolescents (M
MeSH term(s)	Female ; Humans ; Adolescent ; Child ; Male ; Emotions ; Self-Injurious Behavior/psychology ; Surveys and Questionnaires ; Self Report ; Child Abuse/psychology
Language	English
Publishing date	2024-01-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	2028900-5
ISSN	1552-6518 ; 0886-2605
ISSN (online)	1552-6518
ISSN	0886-2605
DOI	10.1177/08862605231197747
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Malignant hyperthermia when dantrolene is not readily available.

Gong, Xiaodan

BMC anesthesiology

2021 Volume 21, Issue 1, Page(s) 119

Abstract: Background: Malignant hyperthermia is a rare but life-threatening pharmacogenetic muscle disorder characterized by abnormal hypermetabolic reactions and commonly triggered in susceptible individuals by volatile anesthetics or succinylcholine, or both. ... ...

Abstract	Background: Malignant hyperthermia is a rare but life-threatening pharmacogenetic muscle disorder characterized by abnormal hypermetabolic reactions and commonly triggered in susceptible individuals by volatile anesthetics or succinylcholine, or both. Unfortunately, the specific medicine dantrolene is not readily available in many countries including China. The aim of this study was to find the characteristics of malignant hyperthermia under the situation that dantrolene is not readily available. Methods: The cases of malignant hyperthermia reported on the most commonly used databases in China from 1985 to 2020 were analyzed. The inclusion criteria were the MH episodes only related to anesthesia. The exclusion criteria were dubious MH episodes only caused by Ketamine administration or MH episodes irrelevant to anesthesia. Independent samples t-test and Pearson's chi-squared test were applied to assess the difference between the survived and death cases. Results: Ninety-two cases of malignant hyperthermia reported on the most commonly used databases in China from 1985 to 2020 were analyzed. Median (IQR [range]) age was 18.5 (11.8-37.0 [0-70.0]) years. Compared with the survived cases, the death cases had higher maximum end-tidal partial pressure of CO Conclusions: In countries that dantrolene is not readily available, early warning, diagnosis, and prompt effective therapies are crucial for MH patients to survive.
MeSH term(s)	Adolescent ; Adult ; Aged ; Arterial Pressure ; Blood Coagulation Disorders/epidemiology ; Carbon Dioxide/metabolism ; Child ; Child, Preschool ; China/epidemiology ; Creatine Kinase/blood ; Creatine Kinase, MB Form/blood ; Dantrolene/supply & distribution ; Databases, Factual ; Female ; Humans ; Hydrogen-Ion Concentration ; Infant ; Infant, Newborn ; Male ; Malignant Hyperthermia/epidemiology ; Middle Aged ; Muscle Relaxants, Central/supply & distribution ; Myoglobin/blood ; Potassium/blood ; Tidal Volume ; Young Adult
Chemical Substances	Muscle Relaxants, Central ; Myoglobin ; Carbon Dioxide (142M471B3J) ; Creatine Kinase (EC 2.7.3.2) ; Creatine Kinase, MB Form (EC 2.7.3.2) ; Dantrolene (F64QU97QCR) ; Potassium (RWP5GA015D)
Language	English
Publishing date	2021-04-16
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2091252-3
ISSN	1471-2253 ; 1471-2253
ISSN (online)	1471-2253
ISSN	1471-2253
DOI	10.1186/s12871-021-01328-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Pressure and temperature dependent

Gong, Xuejun / Dal Corso, Andrea

Journal of physics. Condensed matter : an Institute of Physics journal

2024 Volume 36, Issue 28

Abstract: We present ... ...

Abstract	We present the
Language	English
Publishing date	2024-04-15
Publishing country	England
Document type	Journal Article
ZDB-ID	1472968-4
ISSN	1361-648X ; 0953-8984
ISSN (online)	1361-648X
ISSN	0953-8984
DOI	10.1088/1361-648X/ad3ac3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Fat mass and obesity associated protein inhibits neuronal ferroptosis via the FYN/Drp1 axis and alleviate cerebral ischemia/reperfusion injury.

Zhang, Yi / Gong, Xin

CNS neuroscience & therapeutics

2024 Volume 30, Issue 3, Page(s) e14636

Abstract: Objectives: FTO is known to be involved in cerebral ischemia/reperfusion (I/R) injury. However, its related specific mechanisms during this condition warrant further investigations. This study aimed at exploring the impacts of FTO and the FYN/DRP1 axis ... ...

Abstract	Objectives: FTO is known to be involved in cerebral ischemia/reperfusion (I/R) injury. However, its related specific mechanisms during this condition warrant further investigations. This study aimed at exploring the impacts of FTO and the FYN/DRP1 axis on mitochondrial fission, oxidative stress (OS), and ferroptosis in cerebral I/R injury and the underlying mechanisms. Methods: The cerebral I/R models were established in mice via the temporary middle cerebral artery occlusion/reperfusion (tMCAO/R) and hypoxia/reoxygenation models were induced in mouse hippocampal neurons via oxygen-glucose deprivation/reoxygenation (OGD/R). After the gain- and loss-of-function assays, related gene expression was detected, along with the examination of mitochondrial fission, OS- and ferroptosis-related marker levels, neuronal degeneration and cerebral infarction, and cell viability and apoptosis. The binding of FTO to FYN, m6A modification levels of FYN, and the interaction between FYN and Drp1 were evaluated. Results: FTO was downregulated and FYN was upregulated in tMCAO/R mouse models and OGD/R cell models. FTO overexpression inhibited mitochondrial fission, OS, and ferroptosis to suppress cerebral I/R injury in mice, which was reversed by further overexpressing FYN. FTO overexpression also suppressed mitochondrial fission and ferroptosis to increase cell survival and inhibit cell apoptosis in OGD/R cell models, which was aggravated by additionally inhibiting DRP1. FTO overexpression inhibited FYN expression via the m6A modification to inactive Drp1 signaling, thus reducing mitochondrial fission and ferroptosis and enhancing cell viability in cells. Conclusions: FTO overexpression suppressed FYN expression through m6A modification, thereby subduing Drp1 activity and relieving cerebral I/R injury.
MeSH term(s)	Animals ; Mice ; Alpha-Ketoglutarate-Dependent Dioxygenase FTO/metabolism ; Brain Ischemia/genetics ; Brain Ischemia/metabolism ; Ferroptosis ; Neurons/metabolism ; Reperfusion Injury/genetics ; Reperfusion Injury/metabolism
Chemical Substances	Alpha-Ketoglutarate-Dependent Dioxygenase FTO (EC 1.14.11.33) ; Fyn protein, mouse (EC 2.7.10.2) ; FTO protein, mouse (EC 1.14.11.-) ; Crmp1 protein, mouse
Language	English
Publishing date	2024-03-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2423461-8
ISSN	1755-5949 ; 1755-5930
ISSN (online)	1755-5949
ISSN	1755-5930
DOI	10.1111/cns.14636
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: [A convenient and time-saving method for primary culture of mature white adipocytes from mice].

Shentu, Z / Gong, X / Yang, H

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

2023 Volume 43, Issue 2, Page(s) 213–218

Abstract: Objective: To establish a simple, low-cost and time-saving method for primary culture of mature white adipocytes from mice.: Methods: Mature white adipocytes were isolated from the epididymis and perirenal area of mice for primary culture using a ... ...

Abstract	Objective: To establish a simple, low-cost and time-saving method for primary culture of mature white adipocytes from mice. Methods: Mature white adipocytes were isolated from the epididymis and perirenal area of mice for primary culture using a modified mature adipocyte culture method or the ceiling culture method. The morphology of the cultured mature adipocytes was observed using Oil Red O staining, and the cell viability was assessed with CCK8 method. The expression of PPARγ protein in the cells was detected with Western blotting, and the mRNA expressions of CD36, FAS, CPT1A and FABP4 were detected using RT-qPCR. Results: Oil Red O staining showed a good and uniform morphology of the adipocytes in primary culture using the modified culture method, while the cells cultured using the ceiling culture method exhibited obvious morphological changes. CCK8 assay showed no significant difference in cell viability between freshly isolated mature white adipocytes and the cells obtained with the modified culture method. Western blotting showed that the freshly isolated adipocytes and the cells cultured for 72 h did not differ significantly in the expression levels of PPARγ protein ( Conclusion: We established a convenient and time-saving method for primary culture mature white adipocytes from mice to facilitate further functional studies of mature adipocytes.
MeSH term(s)	Male ; Mice ; Animals ; Adipocytes, White/metabolism ; PPAR gamma/metabolism ; RNA, Messenger ; Cell Differentiation ; 3T3-L1 Cells
Chemical Substances	2-chloro-5-nitrobenzanilide ; PPAR gamma ; oil red O (G7S71FND9B) ; RNA, Messenger
Language	Chinese
Publishing date	2023-03-22
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	2250951-3
ISSN	1673-4254
ISSN	1673-4254
DOI	10.12122/j.issn.1673-4254.2023.02.08
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Information-based matching explains the diversity of cooperation among different populations

Gong, Xiaoming

2022

Abstract: This paper introduces a bilateral matching mechanism to explain why different populations have different levels of cooperation. The traditional game theory assumes that individuals can acquire their neighbor's information without cost after generating ... ...

Abstract	This paper introduces a bilateral matching mechanism to explain why different populations have different levels of cooperation. The traditional game theory assumes that individuals can acquire their neighbor's information without cost after generating information. In fact, the environment and cognition of populations often limit the magnitude of information received by individuals. Our model divides information dynamics into two processes: generation and dissemination. After generating, information starts to disseminate in the population. Individuals match and interact with each other based on the information received and then confirm partnerships, which differs from traditional research's unilateral partner selection process. Specifically, we find a function to simulate two constraints of information acquisition in different populations: information dissemination cost and cognition competence. These two kinds of constraints affect the choice of partnership and then the evolution of cooperation. The game evolved under the condition of information constraints. Through large-scale Monte Carlo simulations, we find that information dissemination and cognition underlie the evolution of cooperation. The lower cost of information dissemination and the more valid cognition of information, the higher level of cooperation. Moreover, deviations in cognition among individuals more sensitively determine the equilibrium cooperation density. As the deviations increase, cooperation density decreases significantly. This paper provides a new explanation for the diversity of cooperation among populations with different information dissemination costs and cognition competence. Comment: There are some code errors in the simulation part, resulting in the wrong experimental results. I need to rewrite the manuscript, so I am requesting withdrawal
Keywords	Computer Science - Computer Science and Game Theory
Subject code	303
Publishing date	2022-06-01
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: [Species and population density of malaria vector

Gong, X / Wu, X / Huo, F / Yu, T / Ge, L / Liu, Y / Li, L

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control

2024 Volume 35, Issue 6, Page(s) 565–572

Abstract: Objective: To investigate the distribution of malaria vector : Methods: The density and species of : Results: A total of 152 243 : Conclusions: Malaria vectors were still widespread in Sichuan Province from 2011 to 2021, ... ...

Abstract	Objective: To investigate the distribution of malaria vector Methods: The density and species of Results: A total of 152 243 Conclusions: Malaria vectors were still widespread in Sichuan Province from 2011 to 2021, and
MeSH term(s)	Animals ; Humans ; Malaria/epidemiology ; Malaria/prevention & control ; Anopheles ; Mosquito Vectors ; Population Density ; China/epidemiology
Language	Chinese
Publishing date	2024-02-27
Publishing country	China
Document type	English Abstract ; Journal Article
ISSN	1005-6661
ISSN	1005-6661
DOI	10.16250/j.32.1374.2023139
Database	MEDical Literature Analysis and Retrieval System OnLINE

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