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  1. AU="Gonschorek, Andreas"
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  1. Book ; Thesis: Die Beeinflussung der kardiorespiratorischen Kopplung durch auditive Stimulation

    Gonschorek, Andreas S.

    eine Methode zur Charakterisierung neurovegetativer Zustände am Menschen

    1996  

    Author's details vorgelegt von: Andreas S. Gonschorek
    Language German
    Size 73 Bl. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Magdeburg, Univ., Diss., 1996
    HBZ-ID HT007344470
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: The effect of repeated concussions on clinical and neurocognitive symptom severity in different contact sports.

    Glaser, Jennifer / Jaeckle, Sarah / Beblo, Thomas / Mueller, Gerhard / Eidenmueller, Andreas M / Schulz, Philipp / Schmehl, Ingo / Rogge, Witold / Hollander, Karsten / Toepper, Max / Gonschorek, Andreas S

    Scandinavian journal of medicine & science in sports

    2024  Volume 34, Issue 4, Page(s) e14626

    Abstract: Introduction: The potential consequences of repeated concussions in sport are well documented. However, it remains unclear whether the cumulative impact of sports-related concussions differs between different contact sports. Therefore, the aim of the ... ...

    Abstract Introduction: The potential consequences of repeated concussions in sport are well documented. However, it remains unclear whether the cumulative impact of sports-related concussions differs between different contact sports. Therefore, the aim of the current study was to investigate the cumulative effects of sports-related concussions on clinical and neurocognitive health in different contact sports.
    Materials and methods: In a prospective multicenter study, we examined 507 (74 females) active professional athletes between 18 and 40 years of age from five different contact sports (soccer, handball, American football, basketball, and ice hockey). Data collection involved concussion history, clinical symptom evaluation, neurocognitive assessment, and the collection of other sports-related information. Composite scores were built for clinical symptoms (such as neck pain and balance disturbances) and for neurocognitive symptoms (such as memory and attention impairments).
    Results: Athletes having suffered 3+ concussions in the past showed disproportionally higher clinical symptom severity than athletes with less than three concussions across all sports. The level of clinical symptom burden in athletes with 3+ concussions indicated mild impairment. The number of past concussions did not affect neurocognitive performance.
    Discussion: Repeated sports-related concussions appear to have a cumulative impact on clinical-but not cognitive-symptom severity. Although clinical symptom burden in athletes with 3+ concussions in the past was not alarmingly high yet in our sample, increased caution should be advised at this point. Despite few exceptions, results are similar for different contact sports, suggesting a similar multidisciplinary concussion management across all types of sport.
    MeSH term(s) Female ; Humans ; Prospective Studies ; Athletes ; Basketball ; Soccer ; Brain Concussion/complications
    Language English
    Publishing date 2024-03-22
    Publishing country Denmark
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1077418-x
    ISSN 1600-0838 ; 0905-7188
    ISSN (online) 1600-0838
    ISSN 0905-7188
    DOI 10.1111/sms.14626
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Non-invasive brain microcurrent stimulation therapy of long-COVID-19 reduces vascular dysregulation and improves visual and cognitive impairment.

    Sabel, Bernhard A / Zhou, Wanshu / Huber, Frank / Schmidt, Florentina / Sabel, Kornelia / Gonschorek, Andreas / Bilc, Mirela

    Restorative neurology and neuroscience

    2021  Volume 39, Issue 6, Page(s) 393–408

    Abstract: Background: An effective treatment is needed for long-COVID patients which suffer from symptoms of vision and/or cognition impairment such as impaired attention, memory, language comprehension, or fatigue.: Objective: Because COVID-19infection causes ...

    Abstract Background: An effective treatment is needed for long-COVID patients which suffer from symptoms of vision and/or cognition impairment such as impaired attention, memory, language comprehension, or fatigue.
    Objective: Because COVID-19infection causes reduced blood flow which may cause neuronal inactivation, we explored if neuromodulation with non-invasive brain stimulation using microcurrent (NIBS), known to enhance blood flow and neuronal synchronization, can reduce these symptoms.
    Methods: Two female long-COVID patients were treated for 10-13 days with alternating current stimulation of the eyes and brain. While one patient (age 40) was infected with the SARS CoV-2 virus, the other (age 72) developed symptoms following AstraZeneca vaccination. Before and after therapy, cognition was assessed subjectively by interview and visual fields quantified using perimetry. One patient was also tested with a cognitive test battery and with a retinal dynamic vascular analyser (DVA), a surrogate marker of vascular dysregulation in the brain.
    Results: In both patients NIBS markedly improved cognition and partially reversed visual field loss within 3-4 days. Cognitive tests in one patient confirmed recovery of up to 40-60% in cognitive subfunctions with perimetry results showing stable and visual field recovery even during follow-up. DVA showed that NIBS reduced vascular dysregulation by normalizing vessel dynamics (dilation/constriction), with particularly noticeable changes in the peripheral veins and arteries.
    Conclusions: NIBS was effective in improving visual and cognitive deficits in two confirmed SARS-COV-2 patients. Because recovery of function was associated with restoration of vascular autoregulation, we propose that (i) hypometabolic, "silent" neurons are the likely biological cause of long-COVID associated visual and cognitive deficits, and (ii) reoxygenation of these "silent" neurons provides the basis for neural reactivation and neurological recovery. Controlled trials are now needed to confirm these observations.
    MeSH term(s) Adult ; Aged ; Brain ; COVID-19/complications ; Cognitive Dysfunction/therapy ; Cognitive Dysfunction/virology ; Electric Stimulation Therapy ; Female ; Humans ; Vision Disorders/therapy ; Vision Disorders/virology
    Language English
    Publishing date 2021-11-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1017098-4
    ISSN 1878-3627 ; 0922-6028
    ISSN (online) 1878-3627
    ISSN 0922-6028
    DOI 10.3233/RNN-211249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Non-invasive brain microcurrent stimulation therapy of long-COVID-19 reduces vascular dysregulation and improves visual and cognitive impairment

    Sabel, Bernhard A. / Zhou, Wanshu / Huber, Frank / Schmidt, Florentina / Sabel, Kornelia / Gonschorek, Andreas / Bilc, Mirela

    Restorative Neurology and Neuroscience

    2021  Volume 39, Page(s) 393–408

    Abstract: Background: An effective treatment is needed for long-COVID patients which suffer from symptoms of vision and/or cognition impairment such as impaired attention, memory, language comprehension, or fatigue. Objective: Because COVID-infection causes ... ...

    Title translation Die nicht-invasive Mikrostromstimulationstherapie des Gehirns mit Long-COVID-19 reduziert die vaskuläre Dysregulation und verbessert die visuelle und kognitive Beeinträchtigung
    Abstract Background: An effective treatment is needed for long-COVID patients which suffer from symptoms of vision and/or cognition impairment such as impaired attention, memory, language comprehension, or fatigue. Objective: Because COVID-infection causes reduced blood flow which may cause neuronal inactivation, we explored if neuromodulation with non-invasive brain stimulation using microcurrent (NIBS), known to enhance blood flow and neuronal synchronization, can reduce these symptoms. Methods: Two female long-COVID patients were treated for 10-13 days with alternating current stimulation of the eyes and brain. While one patient (age 40) was infected with the SARS CoV-2 virus, the other (age 72) developed symptoms following AstraZeneca vaccination. Before and after therapy, cognition was assessed subjectively by interview and visual fields quantified using perimetry. One patient was also tested with a cognitive test battery and with a retinal dynamic vascular analyser (DVA), a surrogate marker of vascular dysregulation in the brain. Results: In both patients NIBS markedly improved cognition and partially reversed visual field loss within 3-4 days. Cognitive tests in one patient confirmed recovery of up to 40-60% in cognitive subfunctions with perimetry results showing stable and visual field recovery even during follow-up. DVA showed that NIBS reduced vascular dysregulation by normalizing vessel dynamics (dilation/constriction), with particularly noticeable changes in the peripheral veins and arteries. Conclusions: NIBS was effective in improving visual and cognitive deficits in two confirmed SARS-COV-2 patients. Because recovery of function was associated with restoration of vascular autoregulation, we propose that (i) hypometabolic, "silent" neurons are the likely biological cause of long-COVID associated visual and cognitive deficits, and (ii) reoxygenation of these "silent" neurons provides the basis for neural reactivation and neurological recovery. Controlled trials are now needed to confirm these observations.
    Keywords Brain Stimulation ; COVID-19 ; Cognition ; Cognitive Impairment ; Genesung ; Hirnstimulation ; Kognition (Erkenntnisprozess) ; Kognitive Beeinträchtigung ; Neuromodulation ; Recovery (Disorders) ; Sehen ; Sehstörungen ; Vision ; Vision Disorders
    Language English
    Document type Article
    ZDB-ID 1017098-4
    ISSN 1878-3627 ; 0922-6028
    ISSN (online) 1878-3627
    ISSN 0922-6028
    DOI 10.3233/RNN-211249
    Database PSYNDEX

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  5. Article: CME: Management des Schädel-Hirn-Traumas. Im Zweifel immer eine Klinikeinweisung veranlassen

    Bohn, Boy / Gonschorek, Andreas S. / Kammler, Gertrud / Jürgens, Christian

    Pädiatrie

    2016  Volume 28, Issue 4, Page(s) 36

    Language German
    Document type Article
    ZDB-ID 2440229-1
    ISSN 1867-2132 ; 1437-1782
    Database Current Contents Medicine

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  6. Article ; Online: Prospective observational cohort study on epidemiology, treatment and outcome of patients with traumatic brain injury (TBI) in German BG hospitals.

    Schwenkreis, Peter / Gonschorek, Andreas / Berg, Florian / Meier, Ullrich / Rogge, Witold / Schmehl, Ingo / Kern, Bodo Christian / Meisel, Hans-Jörg / Wohlfarth, Kai / Gross, Stefan / Sczesny-Kaiser, Matthias / Tegenthoff, Martin / Boschert, Jürgen / Bruckmoser, Ralf / Fürst, Andrea / Schaan, Marc / Strowitzki, Martin / Pingel, Andreas / Jägers, Lisa Linnea /
    Rudolf, Henrik / Trampisch, Hans-Joachim / Lemcke, Johannes

    BMJ open

    2021  Volume 11, Issue 6, Page(s) e045771

    Abstract: Objectives: Since 2000/2001, no large-scale prospective studies addressing traumatic brain injury (TBI) epidemiology in Germany have been published. Our aim was to look for a possible shift in TBI epidemiology described in other European countries, to ... ...

    Abstract Objectives: Since 2000/2001, no large-scale prospective studies addressing traumatic brain injury (TBI) epidemiology in Germany have been published. Our aim was to look for a possible shift in TBI epidemiology described in other European countries, to look for possible changes in TBI management and to identify predictors of 1-year outcome especially in patients with mild TBI.
    Design: Observational cohort study.
    Setting: All patients suffering from a TBI of any degree between 1 October 2014 and 30 September 2015, and who arrived in one of the seven participating BG hospitals within 24 hours after trauma, were included.
    Participants: In total, 3514 patients were included.
    Outcome measures: Initial care, acute hospital care and rehabilitation were documented using standardised documentation forms. A standardised telephone interview was conducted 3 and 12 months after TBI in order to obtain information on outcome.
    Results: Peaks were identified in males in the early 20s and mid-50s, and in both sexes in the late 70s, with 25% of all patients aged 75 or older. A fall was the most frequent cause of TBI, followed by traffic accidents (especially bicyclists). The number of head CT scans increased, and the number of conventional X-rays of the skull decreased compared with 2000/2001. Besides, more patients were offered rehabilitation than before. Though most TBI were classified as mild, one-third of the patients participating in the telephone interview after 12 months still reported troubles attributed to TBI. Negative predictors in mild TBI were female gender, intracranial bleeding and Glasgow Coma Scale (GCS) 13/14.
    Conclusion: The observed epidemiologic shift in TBI (ie, elderly patients, more falls, more bicyclists) calls for targeted preventive measures. The heterogeneity behind the diagnosis 'mild TBI' emphasises the need for defining subgroups not only based on GCS.
    MeSH term(s) Aged ; Brain Injuries, Traumatic/epidemiology ; Brain Injuries, Traumatic/therapy ; Cohort Studies ; Europe ; Female ; Germany/epidemiology ; Glasgow Coma Scale ; Hospitals ; Humans ; Male ; Prospective Studies ; Treatment Outcome
    Language English
    Publishing date 2021-06-04
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2020-045771
    Database MEDical Literature Analysis and Retrieval System OnLINE

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