LIVIVO - Search results -

Search results

Result 1 - 10 of total 21

Search options

Article: Epidemiology and Risk Factors of Mycotic Aneurysm in Patients With Infective Endocarditis and the Impact of its Rupture in Outcomes. Analysis of a National Prospective Cohort.

Calderón-Parra, Jorge / Domínguez, Fernando / González-Rico, Claudia / Arnaiz de Las Revillas, Francisco / Goenaga, Miguel Ángel / Alvarez, I / Muñoz, Patricia / Alonso, David / Rodríguez-García, Raquel / Miró, José María / De Alarcón, Arístides / Antorrena, Isabel / Goikoetxea-Agirre, Josune / Moral-Escudero, Encarnación / Ojeda-Burgos, Guillermo / Ramos-Martínez, Antonio

Open forum infectious diseases

2024 Volume 11, Issue 3, Page(s) ofae121

Abstract: Background: Several aspects of the occurrence and management of mycotic aneurysm (MA) in patients with infective endocarditis (IE) have not been studied.: Objectives: To determine the incidence and factors associated with MA presence and rupture and ... ...

Abstract	Background: Several aspects of the occurrence and management of mycotic aneurysm (MA) in patients with infective endocarditis (IE) have not been studied. Objectives: To determine the incidence and factors associated with MA presence and rupture and to assess the evolution of those initially unruptured MA. Methods: Prospective multicenter cohort including all patients with definite IE between January 2008 and December 2020. Results: Of 4548 IE cases, 85 (1.9%) developed MA. Forty-six (54.1%) had intracranial MA and 39 (45.9%) extracranial MA. Rupture of MA occurred in 39 patients (45.9%). Patients with ruptured MA had higher 1-year mortality (hazard ratio, 2.33; 95% confidence interval, 1.49-3.67). Of the 55 patients with initially unruptured MA, 9 (16.4%) presented rupture after a median of 3 days (interquartile range, 1-7) after diagnosis, being more frequent in intracranial MA (32% vs 3.3%, Conclusions: MA occurred in 2% of the patients with IE. Half of the Mas occurred in an intracranial location. Their rupture is frequent and associated with poor prognosis. A significant proportion of initially unruptured aneurysms result from rupture during the first several days, being more common in intracranial aneurysms. Early specific treatment could potentially lead to better outcomes.
Language	English
Publishing date	2024-03-13
Publishing country	United States
Document type	Clinical Trial
ZDB-ID	2757767-3
ISSN	2328-8957
ISSN	2328-8957
DOI	10.1093/ofid/ofae121
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Non-nosocomial Healthcare-Associated Infective Endocarditis: A Distinct Entity? Data From the GAMES Series (2008-2021).

Alonso-Menchén, David / Bouza, Emilio / Valerio, Maricela / de Alarcón, Arístides / Gutiérrez-Carretero, Encarnación / Miró, José M / Goenaga-Sánchez, Miguel Ángel / Plata-Ciézar, Antonio / González-Rico, Claudia / López-Cortés, Luis Eduardo / Rodríguez Esteban, María Ángeles / Martínez-Marcos, Francisco Javier / Muñoz, Patricia

Open forum infectious diseases

2023 Volume 10, Issue 8, Page(s) ofad393

Abstract: Background: Patients who acquire infective endocarditis (IE) following contact with the healthcare system, but outside the hospital, are classified as having non-nosocomial healthcare-associated IE (HCIE). Our aim was to characterize HCIE and establish ... ...

Abstract	Background: Patients who acquire infective endocarditis (IE) following contact with the healthcare system, but outside the hospital, are classified as having non-nosocomial healthcare-associated IE (HCIE). Our aim was to characterize HCIE and establish whether its etiology, diagnosis, and therapeutic approach suggest it should be considered a distinct entity. Methods: This study retrospectively analyzes data from a nationwide, multicenter, prospective cohort including consecutive cases of IE at 45 hospitals across Spain from 2008 to 2021. HCIE was defined as IE detected in patients in close contact with the healthcare system (eg, patients receiving intravenous treatment, hemodialysis, or institutionalized). The prevalence and main characteristics of HCIE were examined and compared with those of community-acquired IE (CIE) and nosocomial IE (NIE) and with literature data. Results: IE was diagnosed in 4520 cases, of which 2854 (63%) were classified as CIE, 1209 (27%) as NIE, and 457 (10%) as HCIE. Patients with HCIE showed a high burden of comorbidities, a high presence of intravascular catheters, and a predominant staphylococcal etiology, Conclusions: Our data do not support considering HCIE as a distinct entity. HCIE affects a substantial number of patients, is associated with a high mortality, and shares many characteristics with NIE.
Language	English
Publishing date	2023-08-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2757767-3
ISSN	2328-8957
ISSN	2328-8957
DOI	10.1093/ofid/ofad393
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Innate and Adaptive Immune Assessment at Admission to Predict Clinical Outcome in COVID-19 Patients.

San Segundo, David / Arnáiz de Las Revillas, Francisco / Lamadrid-Perojo, Patricia / Comins-Boo, Alejandra / González-Rico, Claudia / Alonso-Peña, Marta / Irure-Ventura, Juan / Olmos, José Manuel / Fariñas, María Carmen / López-Hoyos, Marcos

Biomedicines

2021 Volume 9, Issue 8

Abstract: During the COVID-19 pandemic, many studies have been carried out to evaluate different immune system components to search for prognostic biomarkers of the disease. A broad multiparametric antibody panel of cellular and humoral components of the innate ... ...

Abstract	During the COVID-19 pandemic, many studies have been carried out to evaluate different immune system components to search for prognostic biomarkers of the disease. A broad multiparametric antibody panel of cellular and humoral components of the innate and the adaptative immune response in patients with active SARS-CoV-2 infection has been evaluated in this study. A total of 155 patients were studied at admission into our center and were categorized according to the requirement of oxygen therapy as mild or severe (the latter being those with the requirement). The patients with severe disease were older and had high ferritin, D-dimer, C-reactive protein, troponin, interleukin-6 (IL-6) levels, and neutrophilia with lymphopenia at admission. Moreover, the patients with mild symptoms had significantly increased circulating non-classical monocytes, innate lymphoid cells, and regulatory NK cells. In contrast, severe patients had a low frequency of Th1 and regulatory T cells with increased activated and exhausted CD8 phenotype (CD8
Language	English
Publishing date	2021-07-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720867-9
ISSN	2227-9059
ISSN	2227-9059
DOI	10.3390/biomedicines9080917
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Molecular characterization of multidrug resistant Enterobacterales strains isolated from liver and kidney transplant recipients in Spain.

Fernández-Martínez, Marta / González-Rico, Claudia / Gozalo-Margüello, Mónica / Marco, Francesc / Gracia-Ahufinger, Irene / Aranzamendi, Maitane / Sánchez-Díaz, Ana M / Vicente-Rangel, Teresa / Chaves, Fernando / Calvo Montes, Jorge / Martínez-Martínez, Luis / Fariñas, Maria Carmen

Scientific reports

2021 Volume 11, Issue 1, Page(s) 11875

Abstract: The objective of this study was to analyse the mechanisms of resistance to carbapenems and other extended-spectrum-β-lactams and to determine the genetic relatedness of multidrug-resistant Enterobacterales (MDR-E) causing colonization or infection in ... ...

Abstract	The objective of this study was to analyse the mechanisms of resistance to carbapenems and other extended-spectrum-β-lactams and to determine the genetic relatedness of multidrug-resistant Enterobacterales (MDR-E) causing colonization or infection in solid-organ transplantation (SOT) recipients. Prospective cohort study in kidney (n = 142), liver (n = 98) or kidney/pancreas (n = 7) transplant recipients between 2014 and 2018 in seven Spanish hospitals. We included 531 MDR-E isolates from rectal swabs obtained before transplantation and weekly for 4-6 weeks after the procedure and 10 MDR-E from clinical samples related to an infection. Overall, 46.2% Escherichia coli, 35.3% Klebsiella pneumoniae, 6.5% Enterobacter cloacae, 6.3% Citrobacter freundii and 5.7% other species were isolated. The number of patients with MDR-E colonization post-transplantation (176; 71.3%) was 2.5-fold the number of patients colonized pre-transplantation (71; 28.7%). Extended-spectrum β-lactamases (ESBLs) and carbapenemases were detected in 78.0% and 21.1% of MDR-E isolates respectively. In nine of the 247 (3.6%) transplant patients, the microorganism causing an infection was the same strain previously cultured from surveillance rectal swabs. In our study we have observed a low rate of MDR-E infection in colonized patients 4-6 weeks post-transplantation. E. coli producing bla
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Bacterial Infections/complications ; Bacterial Infections/drug therapy ; Carbapenems/pharmacology ; Citrobacter freundii/drug effects ; Citrobacter freundii/genetics ; Drug Resistance, Multiple, Bacterial/drug effects ; Enterobacter cloacae/drug effects ; Enterobacter cloacae/genetics ; Enterobacteriaceae/drug effects ; Enterobacteriaceae/isolation & purification ; Escherichia coli/drug effects ; Escherichia coli/genetics ; Humans ; Kidney Transplantation/adverse effects ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/isolation & purification ; Liver Transplantation/adverse effects ; Microbial Sensitivity Tests ; Pancreas Transplantation/adverse effects ; Prevalence ; Prospective Studies ; Spain/epidemiology ; Transplant Recipients
Chemical Substances	Anti-Bacterial Agents ; Carbapenems
Language	English
Publishing date	2021-06-04
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-90382-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Usefulness of the COVID-GRAM and CURB-65 scores for predicting severity in patients with COVID-19.

Armiñanzas, Carlos / Arnaiz de Las Revillas, Francisco / Gutiérrez Cuadra, Manuel / Arnaiz, Ana / Fernández Sampedro, Marta / González-Rico, Claudia / Ferrer, Diego / Mora, Víctor / Suberviola, Borja / Latorre, Maite / Calvo, Jorge / Olmos, José Manuel / Cifrián, José Manuel / Fariñas, María Carmen

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2021 Volume 108, Page(s) 282–288

Abstract: Aim: The aim of this study was to determine the usefulness of COVID-GRAM and CURB-65 scores as predictors of the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Caucasian patients.: Methods: This was a ... ...

Abstract	Aim: The aim of this study was to determine the usefulness of COVID-GRAM and CURB-65 scores as predictors of the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Caucasian patients. Methods: This was a retrospective observational study including all adults with SARS-CoV-2 infection admitted to Hospital Universitario Marqués de Valdecilla from February to May 2020. Patients were stratified according to COVID-GRAM and CURB-65 scores as being at low-medium or high risk of critical illness. Univariate analysis, multivariate logistic regression models, receiver operating characteristic curve, and area under the curve (AUC) were calculated. Results: A total of 523 patients were included (51.8% male, 48.2% female; mean age 65.63 years (standard deviation 17.89 years)), of whom 110 (21%) presented a critical illness (intensive care unit admission 10.3%, 30-day mortality 13.8%). According to the COVID-GRAM score, 122 (23.33%) patients were classified as high risk; 197 (37.7%) presented a CURB-65 score ≥2. A significantly greater proportion of patients with critical illness had a high COVID-GRAM score (64.5% vs 30.5%; P < 0.001). The COVID-GRAM score emerged as an independent predictor of critical illness (odds ratio 9.40, 95% confidence interval 5.51-16.04; P < 0.001), with an AUC of 0.779. A high COVID-GRAM score showed an AUC of 0.88 for the prediction of 30-day mortality, while a CURB-65 ≥2 showed an AUC of 0.83. Conclusions: The COVID-GRAM score may be a useful tool for evaluating the risk of critical illness in Caucasian patients with SARS-CoV-2 infection. The CURB-65 score could be considered as an alternative.
MeSH term(s)	Adult ; Aged ; COVID-19 ; Female ; Humans ; Male ; Prognosis ; Retrospective Studies ; SARS-CoV-2 ; Severity of Illness Index
Language	English
Publishing date	2021-05-24
Publishing country	Canada
Document type	Journal Article ; Observational Study
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2021.05.048
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4516: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Humoral/Cellular Immune Discordance in Stem Cell Donors: Impact on Cytomegalovirus-Specific Immune Reconstitution after Related Hematopoietic Transplantation.

Valle-Arroyo, Jorge / Páez-Vega, Aurora / Fernández-Moreno, Raquel / López-Jiménez, Javier / Luna, Alejandro / Duarte, Rafael / Serrano-Martínez, Francisco / Villar, Sara / Fernández-Alonso, Mirian / Reina, Gabriel / González-Rico, Claudia / Fariñas, María C / Rojas, Rafael / Herrera, Concha / Martín, Carmen / García-Torres, Estefanía / Torre-Cisneros, Julián / Cantisán, Sara

Transplantation and cellular therapy

2022 Volume 28, Issue 10, Page(s) 703.e1–703.e8

Abstract: Cytomegalovirus (CMV) reactivation is an important cause of complications after hematopoietic stem cell transplantation (HSCT). Discrepancies between serologic and cellular CMV-specific immune response have been reported. This study evaluated the impact ... ...

Abstract	Cytomegalovirus (CMV) reactivation is an important cause of complications after hematopoietic stem cell transplantation (HSCT). Discrepancies between serologic and cellular CMV-specific immune response have been reported. This study evaluated the impact of lack of CMV-specific CD8
MeSH term(s)	Cytomegalovirus ; Cytomegalovirus Infections/epidemiology ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Immune Reconstitution
Language	English
Publishing date	2022-07-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3062231-1
ISSN	2666-6367
ISSN (online)	2666-6367
DOI	10.1016/j.jtct.2022.07.005
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5082: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Oral decontamination with colistin plus neomycin in solid organ transplant recipients colonized by multidrug-resistant Enterobacterales: a multicentre, randomized, controlled, open-label, parallel-group clinical trial.

Fariñas, Maria Carmen / González-Rico, Claudia / Fernández-Martínez, Marta / Fortún, Jesús / Escudero-Sanchez, Rosa / Moreno, Asunción / Bodro, Marta / Muñoz, Patricia / Valerio, Maricela / Montejo, Miguel / Nieto, Javier / Ruiz-San Millan, Juan Carlos / Casafont-Morencos, Fernando / Martinez-Martínez, Luis / Fariñas-Álvarez, Concepción

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

2020 Volume 27, Issue 6, Page(s) 856–863

Abstract: Objectives: To evaluate the efficacy of oral colistin-neomycin in preventing multidrug-resistant Enterobacterales (MDR-E) infections in solid organ transplant (SOT) recipients.: Methods: Multicentre, open-label, parallel-group, controlled trial with ... ...

Abstract	Objectives: To evaluate the efficacy of oral colistin-neomycin in preventing multidrug-resistant Enterobacterales (MDR-E) infections in solid organ transplant (SOT) recipients. Methods: Multicentre, open-label, parallel-group, controlled trial with balanced (1:1) randomization in five transplant units. SOT recipients were screened for MDR-E intestinal colonization (extended-spectrum β-lactamase or carbapenemase producing) before transplantation and +7 and + 14 days after transplantation and assigned 1:1 to receive treatment with colistin sulfate plus neomycin sulfate for 14 days (decolonization treatment (DT) group) or no treatment (no decolonization treatment (NDT) group). The primary outcome was diagnosis of an MDR-E infection. Safety outcomes were appearance of adverse effects, mainly diarrhoea, rash, nausea and vomiting. Patients were monitored weekly until 30 days after treatment. Intention-to-treat analysis was performed. Results: MDR-E rectal colonization was assessed in 768 SOT recipients; 105 colonized patients were included in the clinical trial, 53 receiving DT and 52 NDT. No significant decrease in the risk of infection by MDR-E was observed in the DT group (9.4%, 5/53) compared to the NDT group (13.5%, 7/52) (relative risk 0.70; 95% confidence interval 0.24-2.08; p 0.517). Four patients (5.6%), three (5.6%) in the DT group and one (1.9%) in the NDT group, developed colistin resistance. Twelve patients (22.7%) in the DT group had diarrhoea, eight related to treatment (15.0%); one patient (1.8%) developed skin rash and another (1.8%) nausea and vomiting. Two patients (3.8%) in the NDT group developed diarrhoea. Conclusions: DT does not reduce MDR-E infections in SOT. Colistin resistance and adverse effects such as diarrhoea are a potential issue that must be taken seriously.
MeSH term(s)	Administration, Oral ; Aged ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/therapeutic use ; Carrier State ; Colistin/administration & dosage ; Colistin/therapeutic use ; Drug Resistance, Multiple, Bacterial ; Drug Therapy, Combination ; Enterobacteriaceae/drug effects ; Enterobacteriaceae Infections/microbiology ; Enterobacteriaceae Infections/prevention & control ; Female ; Humans ; Male ; Middle Aged ; Neomycin/administration & dosage ; Neomycin/therapeutic use ; Organ Transplantation ; Rectum/microbiology ; Transplant Recipients
Chemical Substances	Anti-Bacterial Agents ; Neomycin (I16QD7X297) ; Colistin (Z67X93HJG1)
Language	English
Publishing date	2020-12-24
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Randomized Controlled Trial
ZDB-ID	1328418-6
ISSN	1469-0691 ; 1470-9465 ; 1198-743X
ISSN (online)	1469-0691
ISSN	1470-9465 ; 1198-743X
DOI	10.1016/j.cmi.2020.12.016
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4541: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 284: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Author Correction: Biofilm formation by multidrug resistant Enterobacteriaceae strains isolated from solid organ transplant recipients.

Ramos-Vivas, José / Chapartegui-González, Itziar / Fernández-Martínez, Marta / González-Rico, Claudia / Fortún, Jesús / Escudero, Rosa / Marco, Francesc / Linares, Laura / Montejo, Miguel / Aranzamendi, Maitane / Muñoz, Patricia / Valerio, Maricela / Aguado, Jose María / Resino, Elena / Ahufinger, Irene Gracia / Vega, Aurora Paz / Martínez-Martínez, Luis / Fariñas, María Carmen

Scientific reports

2020 Volume 10, Issue 1, Page(s) 7452

Abstract: An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

Abstract	An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Language	English
Publishing date	2020-04-29
Publishing country	England
Document type	Published Erratum
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-020-60496-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Adherence to Human Colon Cells by Multidrug Resistant

Ramos-Vivas, José / Chapartegui-González, Itziar / Fernández-Martínez, Marta / González-Rico, Claudia / Barrett, John / Fortún, Jesús / Escudero, Rosa / Marco, Francesc / Linares, Laura / Nieto, Javier / Aranzamendi, Maitane / Muñoz, Patricia / Valerio, Maricela / Aguado, Jose María / Chaves, Fernando / Gracia-Ahufinger, Irene / Paez-Vega, Aurora / Martínez-Martínez, Luis / Fariñas, María Carmen

Frontiers in cellular and infection microbiology

2020 Volume 10, Page(s) 447

Abstract: Enterobacteria species are common causes of hospital-acquired infections, which are associated with high morbidity and mortality rates. Immunocompromised patients such as solid organ transplant (SOT) recipients are especially at risk because they are ... ...

Abstract	Enterobacteria species are common causes of hospital-acquired infections, which are associated with high morbidity and mortality rates. Immunocompromised patients such as solid organ transplant (SOT) recipients are especially at risk because they are frequently exposed to antibiotics in the course of their treatments. In this work, we used a collection of 106
MeSH term(s)	Biofilms ; Citrobacter freundii ; Colon ; Escherichia coli ; Humans ; Organ Transplantation
Language	English
Publishing date	2020-09-16
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2619676-1
ISSN	2235-2988 ; 2235-2988
ISSN (online)	2235-2988
ISSN	2235-2988
DOI	10.3389/fcimb.2020.00447
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Infective Endocarditis in Patients With Bicuspid Aortic Valve or Mitral Valve Prolapse.

Zegri-Reiriz, Isabel / de Alarcón, Arístides / Muñoz, Patricia / Martínez Sellés, Manuel / González-Ramallo, Victor / Miro, Jose M / Falces, Carles / Gonzalez Rico, Claudia / Kortajarena Urkola, Xabier / Lepe, José Antonio / Rodriguez Alvarez, Regino / Reguera Iglesias, Jose Maria / Navas, Enrique / Dominguez, Fernando / Garcia-Pavia, Pablo

Journal of the American College of Cardiology

2018 Volume 71, Issue 24, Page(s) 2731–2740

Abstract: Background: There is little information concerning infective endocarditis (IE) in patients with bicuspid aortic valve (BAV) or mitral valve prolapse (MVP). Currently, IE antibiotic prophylaxis (IEAP) is not recommended for these conditions.: ... ...

Abstract	Background: There is little information concerning infective endocarditis (IE) in patients with bicuspid aortic valve (BAV) or mitral valve prolapse (MVP). Currently, IE antibiotic prophylaxis (IEAP) is not recommended for these conditions. Objectives: This study sought to describe the clinical and microbiological features of IE in patients with BAV and MVP and compare them with those of IE patients with and without IEAP indication, to determine the potential benefit of IEAP in these conditions. Methods: This analysis involved 3,208 consecutive IE patients prospectively included in the GAMES (Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España) registry at 31 Spanish hospitals. Patients were classified as high-risk IE with IEAP indication (high-risk group; n = 1,226), low- and moderate-risk IE without IEAP indication (low/moderate-risk group; n = 1,839), and IE with BAV (n = 54) or MVP (n = 89). Results: BAV and MVP patients had a higher incidence of viridans group streptococci IE than did high-risk group and low/moderate-risk group patients (35.2% and 39.3% vs. 12.1% and 15.0%, respectively; all p < 0.01). A similar pattern was seen for IE from suspected odontologic origin (14.8% and 18.0% vs. 5.8% and 6.0%; all p < 0.01). BAV and MVP patients had more intracardiac complications than did low/moderate-risk group (50% and 47.2% vs. 30.6%, both p < 0.01) patients and were similar to high-risk group patients. Conclusions: IE in patients with BAV and MVP have higher rates of viridans group streptococci IE and IE from suspected odontologic origin than in other IE patients, with a clinical profile similar to that of high-risk IE patients. Our findings suggest that BAV and MVP should be classified as high-risk IE conditions and the case for IEAP should be reconsidered.
MeSH term(s)	Adult ; Aged ; Antibiotic Prophylaxis ; Aortic Valve/abnormalities ; Bicuspid Aortic Valve Disease ; Endocarditis/microbiology ; Endocarditis/prevention & control ; Female ; Heart Valve Diseases/complications ; Humans ; Male ; Middle Aged ; Mitral Valve Prolapse/complications ; Registries
Language	English
Publishing date	2018-06-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2018.03.534
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1846: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 196: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito