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  1. Article ; Online: Correlación de fórmulas para gasto energético con calorimetría indirecta en pacientes críticos.

    López-Villegas, Angélica / Gómez-González, María Natalia / González-Carrillo, Pedro Luis

    Revista medica del Instituto Mexicano del Seguro Social

    2023  Volume 61, Issue Suppl 2, Page(s) S246–S253

    Abstract: Background: Nutrition in the Intensive Care Unit (ICU) is a cornerstone; however, energy requirements are a controversial issue that has not yet been resolved. Calorimetry is the gold standard for calculating energy expenditure, but it is expensive and ... ...

    Title translation Correlation of equations for energy expenditure with indirect calorimetry in critically ill patients.
    Abstract Background: Nutrition in the Intensive Care Unit (ICU) is a cornerstone; however, energy requirements are a controversial issue that has not yet been resolved. Calorimetry is the gold standard for calculating energy expenditure, but it is expensive and not available in all ICU areas. Formulas have been developed to calculate basal energy expenditure (BAE) and make the process easier.
    Objective: To validate the predictive formulas of BAE compared to that obtained with ventilatory indirect calorimetry (IC) within the nutritional assessment in ICU patients.
    Material and methods: Analytical cross-sectional retrolective study. We performed BAE measurement on patients in the ICU of a third level hospital with ventilatory indirect calorimetry and compared the results obtained with those of the Harris Benedict, Muffin-St. Jeor, Institute of Medicine, and Faisy equations.
    Results: A total of 49 patients were included; a moderate correlation with statistical significance was found between the BAE measurements obtained by indirect calorimetry, with those obtained by four predictive equations that were studied. The Faisy equation obtained the strongest correction with r = 0.461 (p = 0.001).
    Conclusion: The correlation between the BAE obtained by predictive equations and by IC goes from mild to moderate, due to the heterogeneity of critical patients and their changing nature throughout their disease.
    MeSH term(s) Humans ; Calorimetry, Indirect/methods ; Critical Illness ; Cross-Sectional Studies ; Energy Metabolism ; Nutritional Status
    Language Spanish
    Publishing date 2023-09-18
    Publishing country Mexico
    Document type English Abstract ; Journal Article ; Observational Study
    ZDB-ID 732133-8
    ISSN 2448-5667 ; 0443-5117 ; 0484-7849
    ISSN (online) 2448-5667
    ISSN 0443-5117 ; 0484-7849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Inserción con técnica ecoguiada y la proporción de trombosis asociada a catéter.

    Godínez-García, Francisco / López-Briones, José Sergio / Hernández-González, Martha Alicia / González-Carrillo, Pedro Luis

    Revista medica del Instituto Mexicano del Seguro Social

    2023  Volume 61, Issue Suppl 2, Page(s) S90–S95

    Abstract: Background: Central venous accesses are of great importance in daily medical practice. Insertion into the jugular vein is common due to its accessibility. Catheter-associated venous thrombosis is a relatively common medium-term complication. The use of ... ...

    Title translation Ultrasound-guided insertion and the proportion of catheter-associated thrombosis.
    Abstract Background: Central venous accesses are of great importance in daily medical practice. Insertion into the jugular vein is common due to its accessibility. Catheter-associated venous thrombosis is a relatively common medium-term complication. The use of ultrasound to guide catheterization offers multiple advantages and promises to make vascular access installation a safer technique.
    Objective: To compare the proportion of catheter-associated jugular thrombosis when an anatomical landmark technique is used with respect to the ultrasound-guided technique.
    Material and methods: An observational, cross-sectional, and analytical study that compares the frequency of thrombosis when the ultrasound-guided technique was used concerning anatomical reference technique in patients in an intensive care unit.
    Results: A total of 91 patients were studied: in 44 an ultrasound-guided technique was used, and in 47 anatomical references. A single case of mural thrombosis (2.7%) was observed in the ultrasound-guided insertion group vs. 11 cases (23.4%) in the other group, resulting in a significant association between the anatomical reference insertion technique and thrombosis. Chi squared (1, n = 91) = 8.86, p = 0.004.
    Conclusion: The proportion of catheter-associated jugular thrombosis is greater when an anatomical reference technique is used compared to the ultrasound-guided technique.
    MeSH term(s) Humans ; Catheterization, Central Venous/adverse effects ; Catheters ; Cross-Sectional Studies ; Thrombosis/diagnostic imaging ; Thrombosis/etiology ; Ultrasonography, Interventional/methods
    Language Spanish
    Publishing date 2023-09-18
    Publishing country Mexico
    Document type Comparative Study ; English Abstract ; Journal Article ; Observational Study
    ZDB-ID 732133-8
    ISSN 2448-5667 ; 0443-5117 ; 0484-7849
    ISSN (online) 2448-5667
    ISSN 0443-5117 ; 0484-7849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Delta del índice neutrófilo linfocito y mortalidad en infección COVID-19.

    Rosales-López, Sandra Luz / Fernández-Hernández, Juan Pablo / Hernández-González, Martha Alicia / Solorio-Meza, Sergio Eduardo / González-Carrillo, Pedro Luis / Guardado-Mendoza, Rodolfo

    Revista medica del Instituto Mexicano del Seguro Social

    2022  Volume 60, Issue 6, Page(s) 640–648

    Abstract: Background: Acute respiratory distress syndrome, due to SARS-CoV-2, is a worldwide health problem. The neutrophil-lymphocyte index allows risk stratification in patients with severe and poor prognostic data, since it reflects the inflammatory state.: ... ...

    Title translation Delta of neutrophil lymphocyte index and mortality in covid-19 disease.
    Abstract Background: Acute respiratory distress syndrome, due to SARS-CoV-2, is a worldwide health problem. The neutrophil-lymphocyte index allows risk stratification in patients with severe and poor prognostic data, since it reflects the inflammatory state.
    Objective: To determine whether the Neutrophil-Lymphocyte Index delta predicts mortality in patients with COVID-19.
    Material and methods: We conducted a longitudinal, comparative study in patients with COVID-19, older than 18 years, admitted to the ICU. We evaluated HAS, DM, obesity, COPD, asthma, PaO2/FiO2, tomographic severity. On admission and on days 3 and 7 we measured Neutrophil-Lymphocyte Index, SOFA and APACHE score. For statistical analysis, we performed ROC and Kaplan-Meyer curves.
    Results: We included 180 patients with COVID-19, 63 died (35%). Delta INL1(Day1-day3)>4.11 was associated with mortality (AUC:0.633); sensitivity 55.56% and specificity 77.78%, CI95 0.55-0.70, for delta INL2 (Day1-day7)>8.95 (AUC:0.623); sensitivity 44.44% and specificity 84.62%, CI95 0.54-0.69. Difference in survival was observed for Delta1. SOFA scale >6, was associated with more days of mechanical ventilation and lower PaO2/FiO2 (p<0.001).
    Conclusions: INL delta between the day of ICU admission and the 3rd day of evolution is a predictor of mortality in critically ill patients.
    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Neutrophils ; Respiratory Distress Syndrome ; Lymphocytes ; Intensive Care Units ; Retrospective Studies
    Language Spanish
    Publishing date 2022-10-25
    Publishing country Mexico
    Document type English Abstract ; Journal Article
    ZDB-ID 732133-8
    ISSN 2448-5667 ; 0443-5117 ; 0484-7849
    ISSN (online) 2448-5667
    ISSN 0443-5117 ; 0484-7849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Paraneoplastic opsoclonus-myoclonus syndrome secondary to melanoma metastasis form occult primary cancer.

    Mondragón, Jaime D / Jiménez-Zarazúa, Omar / Vélez-Ramírez, Lourdes N / Martínez-Rivera, María Andrea / Enríquez-Maciel, Samnir / González-Guzmán, Jesús / Alvarez-Delgado, Martha Mercedes / González-Carrillo, Pedro Luis

    Case reports in neurology

    2019  Volume 11, Issue 1, Page(s) 66–79

    Abstract: Introduction: Opsoclonus-myoclonus syndrome (OMS) is an inflammatory neurological disorder, often requiring a prompt medical evaluation. Among the diverse etiologies associated with OMS are autoimmune, infectious, paraneoplastic, and systemic diseases, ... ...

    Abstract Introduction: Opsoclonus-myoclonus syndrome (OMS) is an inflammatory neurological disorder, often requiring a prompt medical evaluation. Among the diverse etiologies associated with OMS are autoimmune, infectious, paraneoplastic, and systemic diseases, and drug intoxication.
    Clinical summary: The case of a 36-year-old female with a disabling holocranial headache, sudden loss of consciousness, aggressive behavior, vertigo, and a personal history of somatoform disorder and major depression is presented here. After hospital admission, the patient developed sudden stereotyped movements in all four extremities and oculogyric crises compatible with OMS. Cerebrospinal fluid analysis, viral and autoimmune assays, as well as blood, urine, and bronchial secretion cultures, drug metabolite urinalysis, and tumor markers were all negative. Furthermore, brain computed tomography (CT) and brain magnetic resonance imaging, along with thoraco-abdominopelvic CT and electroencephalography, were also all negative. The patient suffered type one respiratory insufficiency after 72 h of hospitalization, requiring an endotracheal tube. After 13 days the patient suffered cardiac arrest. Necropsy was performed reporting lymph nodes with a poorly differentiated malignant neoplastic lesion, HMB-45, melan-A, vimentin, and S-100 positive, compatible with melanoma metastasis from an occult primary cancer.
    Discussion: While the incidence of melanoma of unknown primary is between 2.6 and 3.2%, with a median overall survival ranging between 24 and 127 months, when melanoma patients develop OMS their survival is markedly decreased. Although only 5 cases of paraneoplastic OMS secondary to melanoma have been reported in the literature, all had a poor prognosis, dying within 8 months of OMS onset.
    Language English
    Publishing date 2019-02-28
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2505302-4
    ISSN 1662-680X
    ISSN 1662-680X
    DOI 10.1159/000497034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Headache, Delirium or Encephalitis? A Case of Residual Mutism Secondary to Anti-NMDA Receptor Encephalitis.

    Jiménez-Zarazúa, Omar / Martínez-Rivera, María Andrea / González-Carrillo, Pedro Luis / Vélez-Ramírez, Lourdes N / Alcocer-León, María / Tafoya-Rojas, Sandra X L / Becerra-Baez, Angélica M / Bravo-Martínez, Mariana A / Mondragón, Jaime D

    Case reports in neurology

    2019  Volume 11, Issue 3, Page(s) 330–343

    Abstract: Encephalitis is a heterogeneous syndrome that is diagnosed through clinical assessment and the assistance of laboratory, neuroimaging and electroencephalographic workup. Over the past 10 years, autoimmune encephalitis has been more frequently recognized; ...

    Abstract Encephalitis is a heterogeneous syndrome that is diagnosed through clinical assessment and the assistance of laboratory, neuroimaging and electroencephalographic workup. Over the past 10 years, autoimmune encephalitis has been more frequently recognized; however, most reports come from highly specialized hospital settings. Anti-N-methyl-D-aspartate receptor (NDMAR) encephalitis has been associated with paraneoplastic encephalitis syndromes and was first recognized in 2005. We present the case of a 34-year-old male patient who debuted clinically with a headache associated with neuropsychiatric symptoms (i.e., visual and auditory hallucinations, anxiety, aggressiveness) and memory deficits, progressing to autonomic dysfunction (i.e., tachycardia and hypertension), seizures, and stupor with catatonic features. Initially, infectious, metabolic, and toxicological etiologies were excluded; followed by the assessment of immunological and paraneoplastic etiologies, yielding positive IgG levels for anti-NMDAR antibodies. The patient was treated successfully with systemic steroid therapy and therapeutic plasmapheresis, while mutism was the only sequela. Although large case series reporting on paraneoplastic and autoimmune anti-NMDAR encephalitis have been reported in the literature in recent years, this case is of particular importance due to the stepwise differential diagnosis and treatment management procedure that was used in a regional but not highly specialized hospital setting.
    Language English
    Publishing date 2019-12-06
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2505302-4
    ISSN 1662-680X
    ISSN 1662-680X
    DOI 10.1159/000504016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Headache, Delirium or Encephalitis? A Case of Residual Mutism Secondary to Anti-NMDA Receptor Encephalitis

    Jiménez-Zarazúa, Omar / Martínez-Rivera, María Andrea / González-Carrillo, Pedro Luis / Vélez-Ramírez, Lourdes N. / Alcocer-León, María / Tafoya-Rojas, Sandra X.L. / Becerra-Baez, Angélica M. / Bravo-Martínez, Mariana A. / Mondragón, Jaime D.

    Case Reports in Neurology

    2019  Volume 11, Issue 3, Page(s) 330–343

    Abstract: Encephalitis is a heterogeneous syndrome that is diagnosed through clinical assessment and the assistance of laboratory, neuroimaging and electroencephalographic workup. Over the past 10 years, autoimmune encephalitis has been more frequently recognized; ...

    Institution Department of Internal Medicine, Hospital General León, León, Mexico
    Department of Medicine and Nutrition, Universidad de Guanajuato, León, Mexico
    Department of Critical Care and Neurocritical Care, Hospital General León, León, Mexico
    Department of Radiology, Hospital General León, León, Mexico
    Department of Internal Medicine, Hospital Regional ISSSTE León, León, Mexico
    Faculty of Medicine, Universidad del Valle de México, León, Mexico
    Faculty of Medicine, Universidad Latina de México, Celaya, Mexico
    Department of Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Alzheimer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Abstract Encephalitis is a heterogeneous syndrome that is diagnosed through clinical assessment and the assistance of laboratory, neuroimaging and electroencephalographic workup. Over the past 10 years, autoimmune encephalitis has been more frequently recognized; however, most reports come from highly specialized hospital settings. Anti-N-methyl-D-aspartate receptor (NDMAR) encephalitis has been associated with paraneoplastic encephalitis syndromes and was first recognized in 2005. We present the case of a 34-year-old male patient who debuted clinically with a headache associated with neuropsychiatric symptoms (i.e., visual and auditory hallucinations, anxiety, aggressiveness) and memory deficits, progressing to autonomic dysfunction (i.e., tachycardia and hypertension), seizures, and stupor with catatonic features. Initially, infectious, metabolic, and toxicological etiologies were excluded; followed by the assessment of immunological and paraneoplastic etiologies, yielding positive IgG levels for anti-NMDAR antibodies. The patient was treated successfully with systemic steroid therapy and therapeutic plasmapheresis, while mutism was the only sequela. Although large case series reporting on paraneoplastic and autoimmune anti-NMDAR encephalitis have been reported in the literature in recent years, this case is of particular importance due to the stepwise differential diagnosis and treatment management procedure that was used in a regional but not highly specialized hospital setting.
    Keywords Anti-N-methyl-D-aspartate receptor encephalitis ; Delirium ; Headache disorders ; Mutism
    Language English
    Publishing date 2019-12-06
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Case Series – Headache ; This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC).
    ZDB-ID 2505302-4
    ISSN 1662-680X ; 1662-680X
    ISSN (online) 1662-680X
    ISSN 1662-680X
    DOI 10.1159/000504016
    Database Karger publisher's database

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  7. Article: Paraneoplastic opsoclonus-myoclonus syndrome secondary to melanoma metastasis form occult primary cancer

    Mondragón, Jaime D. / Jiménez-Zarazúa, Omar / Vélez-Ramírez, Lourdes N. / Martínez-Rivera, María Andrea / Enríquez-Maciel, Samnir / González-Guzmán, Jesús / Alvarez-Delgado, Martha Mercedes / González-Carrillo, Pedro Luis

    Case Reports in Neurology

    2019  Volume 11, Issue 1, Page(s) 66–79

    Abstract: Introduction: Opsoclonus-myoclonus syndrome (OMS) is an inflammatory neurological disorder, often requiring a prompt medical evaluation. Among the diverse etiologies associated with OMS are autoimmune, infectious, paraneoplastic, and systemic diseases, ... ...

    Institution Department of Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    University of Groningen, University Medical Center Groningen, Alzheimer Research Center Groningen, Groningen, The Netherlands
    Department of Internal Medicine, Hospital General León, León de los Aldama, Mexico
    Department of Medicine and Nutrition, Universidad de Guanajuato, Guanajuato, Mexico
    Department of Radiology, Hospital General León, León de los Aldama, Mexico
    Department of Pathology, Hospital General León, León de los Aldama, Mexico
    Department of Critical Care, Hospital General León, León de los Aldama, Mexico
    Abstract Introduction: Opsoclonus-myoclonus syndrome (OMS) is an inflammatory neurological disorder, often requiring a prompt medical evaluation. Among the diverse etiologies associated with OMS are autoimmune, infectious, paraneoplastic, and systemic diseases, and drug intoxication. Clinical Summary: The case of a 36-year-old female with a disabling holocranial headache, sudden loss of consciousness, aggressive behavior, vertigo, and a personal history of somatoform disorder and major depression is presented here. After hospital admission, the patient developed sudden stereotyped movements in all four extremities and oculogyric crises compatible with OMS. Cerebrospinal fluid analysis, viral and autoimmune assays, as well as blood, urine, and bronchial secretion cultures, drug metabolite urinalysis, and tumor markers were all negative. Furthermore, brain computed tomography (CT) and brain magnetic resonance imaging, along with thoraco-abdominopelvic CT and electroencephalography, were also all negative. The patient suffered type one respiratory insufficiency after 72 h of hospitalization, requiring an endotracheal tube. After 13 days the patient suffered cardiac arrest. Necropsy was performed reporting lymph nodes with a poorly differentiated malignant neoplastic lesion, HMB-45, melan-A, vimentin, and S-100 positive, compatible with melanoma metastasis from an occult primary cancer. Discussion: While the incidence of melanoma of unknown primary is between 2.6 and 3.2%, with a median overall survival ranging between 24 and 127 months, when melanoma patients develop OMS their survival is markedly decreased. Although only 5 cases of paraneoplastic OMS secondary to melanoma have been reported in the literature, all had a poor prognosis, dying within 8 months of OMS onset.
    Keywords Immunohistochemistry ; Melanoma ; Occult primary neoplasms ; Opsoclonus-myoclonus syndrome ; Paraneoplastic syndrome
    Language English
    Publishing date 2019-02-28
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Case Report ; This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC).
    ZDB-ID 2505302-4
    ISSN 1662-680X ; 1662-680X
    ISSN (online) 1662-680X
    ISSN 1662-680X
    DOI 10.1159/000497034
    Database Karger publisher's database

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