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  1. Article ; Online: Reales decretos de declaración y prórroga del estado de alarma

    González López, Juan José

    Gabilex: Revista del Gabinete Jurídico de Castilla-La Mancha, ISSN 2386-8104, Nº. 21, 2020 (Ejemplar dedicado a: ANALISIS JURÍDICO DERIVADO DEL ESTADO DE ALARMA POR LA CRISIS SANITARIA OCASIONADA POR EL COVID-19), pags. 109-132

    Reales decretos de declaración y prórroga del estado de alarma

    2020  

    Abstract: The purpose of this work is to briefly analyse three specific aspects of the Royal Decrees required by article 116.2 of the Spanish Constitution both to declare and to extend “the state of alarm” (equivalent to the state of emergency in British and ... ...

    Abstract The purpose of this work is to briefly analyse three specific aspects of the Royal Decrees required by article 116.2 of the Spanish Constitution both to declare and to extend “the state of alarm” (equivalent to the state of emergency in British and American systems). Firstly, their legal nature as actual laws. Secondly, the control exercised over them by the Constitutional Court through the question of unconstitutionality and the appeal for protection. Finally, some notes are made about the public liability that can arise form the aforementioned Royal Decrees.

    El objeto del presente trabajo es analizar sucintamente tres aspectos concretos de los Reales Decretos en virtud de los cuales se declara y, en su caso, prorroga el estado de alarma contemplado en el artículo 116.2 de la Constitución Española. En primer lugar, su naturaleza jurídica como disposiciones con fuerza de ley. En segundo lugar, su control jurisdiccional por el Tribunal Constitucional a través de la cuestión de inconstitucionalidad y el recurso de amparo. Finalmente se realizan algunos apuntes acerca de la responsabilidad patrimonial derivada de los Reales Decretos antedichos.
    Keywords Reales Decretos estado de alarma naturaleza jurídica ; control jurisdiccional ; responsabilidad patrimonial ; Royal Decrees state of alarm legal nature ; jurisdictional control ; patrimonial responsibility ; covid19
    Language Spanish
    Publishing country es
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: First documented outbreak of arthritis caused by Kingella kingae in a Spanish childcare center.

    Guarch-Ibáñez, Borja / Cabacas, Alicia / González-López, Juan José / García-González, María Del Mar / Mora, Carme / Villalobos, Pilar

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2022  Volume 40, Issue 4, Page(s) 187–189

    Abstract: Background: Recently, Kingella kingae (K. kingae) has been described as the most common agent of skeletal system infections in children 6 months-2 years of age. More exceptional is the clinical presentation in clusters of invasive K. kingae infections. ... ...

    Abstract Background: Recently, Kingella kingae (K. kingae) has been described as the most common agent of skeletal system infections in children 6 months-2 years of age. More exceptional is the clinical presentation in clusters of invasive K. kingae infections. We describe the investigation of the first outbreak of 3 cases of arthritis caused by K. kingae documented in Spain detected in a daycare center in Roses, Girona.
    Patients and methods: In December of 2015 surveillance throat swabs obtained from all attendees from the same class of the index daycare center were assessed to study the prevalence of K. kingae colonization. The sample was composed of 9 toddlers (range: 16-23 months of age). Investigation was performed by culture and K. kingae-specific RT-PCR. Combined amoxicillin-rifampicin prophylaxis was offered to all attendees who were colonized by K. kingae. Following antimicrobial prophylaxis, a new throat swab was taken to confirm bacterial eradication.
    Results: K. kingae was detected by RT-PCR throat swabs in the 3 index cases and 5 of the 6 daycare attendees. Cultures were negative in all cases. After administration of prophylactic antibiotics, 3 toddlers were still positive for K. kingae-specific RT-PCR.
    Conclusions: Clusters of invasive K. kingae infections can occur in daycare facilities and closed communities. Increased awareness and use of sensitive detection methods are needed to identify and adequately investigate outbreaks of K. kingae disease. In our experience, the administration of prophylactic antibiotics could result in partial eradication of colonization. No further cases of disease were detected after prophylaxis.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Arthritis, Infectious/microbiology ; Child ; Child Care ; Disease Outbreaks ; Humans ; Kingella kingae/genetics ; Neisseriaceae Infections/drug therapy ; Neisseriaceae Infections/epidemiology ; Neisseriaceae Infections/microbiology
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-02-28
    Publishing country Spain
    Document type Journal Article
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimce.2022.02.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Catastrophic

    Ruiz-Rodríguez, Juan Carlos / Chiscano-Camón, Luis / Maldonado, Carolina / Ruiz-Sanmartin, Adolf / Martin, Laura / Bajaña, Ivan / Bastidas, Juliana / Lopez-Martinez, Rocio / Franco-Jarava, Clara / González-López, Juan José / Ribas, Vicent / Larrosa, Nieves / Riera, Jordi / Nuvials-Casals, Xavier / Ferrer, Ricard

    Antibiotics (Basel, Switzerland)

    2024  Volume 13, Issue 2

    Abstract: Streptococcal toxic shock syndrome (STTS) is a critical medical emergency marked by high morbidity and mortality, necessitating swift awareness, targeted treatment, and early source control due to its rapid symptom manifestation. This report focuses on a ...

    Abstract Streptococcal toxic shock syndrome (STTS) is a critical medical emergency marked by high morbidity and mortality, necessitating swift awareness, targeted treatment, and early source control due to its rapid symptom manifestation. This report focuses on a cohort of 13 patients admitted to Vall d'Hebron University Hospital Intensive Care Unit, Barcelona, from November 2022 to March 2023, exhibiting invasive
    Language English
    Publishing date 2024-02-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics13020187
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Use of Biomarkers to Improve 28-Day Mortality Stratification in Patients with Sepsis and SOFA ≤ 6.

    Baldirà, Jaume / Ruiz-Rodríguez, Juan Carlos / Ruiz-Sanmartin, Adolfo / Chiscano, Luis / Cortes, Alejandro / Sistac, Diego Ángeles / Ferrer-Costa, Roser / Comas, Inma / Villena, Yolanda / Larrosa, Maria Nieves / González-López, Juan José / Ferrer, Ricard

    Biomedicines

    2023  Volume 11, Issue 8

    Abstract: Early diagnosis and appropriate treatments are crucial to reducing mortality risk in septic patients. Low SOFA scores and current biomarkers may not adequately discern patients that could develop severe organ dysfunction or have an elevated mortality ... ...

    Abstract Early diagnosis and appropriate treatments are crucial to reducing mortality risk in septic patients. Low SOFA scores and current biomarkers may not adequately discern patients that could develop severe organ dysfunction or have an elevated mortality risk. The aim of this prospective observational study was to evaluate the predictive value of the biomarkers mid-regional pro-adrenomedullin (MR-proADM), procalcitonin (PCT), C-reactive protein (CRP), and lactate for 28-day mortality in patients with sepsis, and patients with a SOFA score ≤6. 284 were included, with a 28-day all-cause mortality of 8.45% (
    Language English
    Publishing date 2023-07-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11082149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Mycotic Aneurysm of Internal Carotid Artery Secondary to Livestock-associated Methicillin-resistant Staphylococcus Aureus Clonal Complex CC398.

    Tenezaca-Sari, Angel Xavier / Gil-Sala, Daniel / Escolà-Vergé, Laura / Lung, Mayli / González-López, Juan José / Bellmunt-Montoya, Sergi

    Annals of vascular surgery

    2021  Volume 78, Page(s) 379.e7–379.e10

    Abstract: The aim of this article is to present a case of mycotic aneurysm of internal carotid artery secondary to livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) treated with resection and common-to-internal carotid artery bypass with ... ...

    Abstract The aim of this article is to present a case of mycotic aneurysm of internal carotid artery secondary to livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) treated with resection and common-to-internal carotid artery bypass with autologous vein graft in a male pig farmer. A 69-year-old man, pig farmer, with recent dental extraction was admitted with a right cervical pulsatile mass, dysphonia, pain, leukocytosis and elevated C-reactive protein (CRP). Ultrasonography (US) and computed tomography angiography (CTA) showed a 3.9 × 4.5 cm mycotic aneurysm of right internal carotid artery with hypermetabolic uptake in positron emission tomography (PET) scan. Resection of the mycotic aneurysm and a common-to-internal carotid artery bypass with major saphenous vein graft were performed. LA-MRSA clonal complex (CC) 398 was detected in intraoperative samples and antibiotic therapy was changed according to antibiogram. Patient was discharged at the seventh postoperative day and received antibiotic therapy for 6 weeks. US 12 months later showed patency of the bypass without collections. Mycotic aneurysms of internal carotid artery are very infrequent. MRSA isolation is rare, and to the best of our knowledge this is the first case caused by multi-drug resistant LA-MRSA CC398. The treatment includes mycotic aneurysm resection and reconstruction with venous graft bypass plus intensive antibiotic therapy.
    MeSH term(s) Aged ; Aneurysm, Infected/diagnosis ; Aneurysm, Infected/microbiology ; Aneurysm, Infected/surgery ; Animals ; Anti-Bacterial Agents/therapeutic use ; Bacterial Zoonoses ; Carotid Artery, Internal/cytology ; Carotid Artery, Internal/microbiology ; Carotid Artery, Internal/surgery ; Farmers ; Humans ; Male ; Methicillin-Resistant Staphylococcus aureus/isolation & purification ; Saphenous Vein/transplantation ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/microbiology ; Staphylococcal Infections/surgery ; Staphylococcal Infections/transmission ; Sus scrofa/microbiology ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-09-03
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2021.06.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: First documented outbreak of arthritis caused by Kingella kingae in a Spanish childcare center.

    Guarch-Ibáñez, Borja / Cabacas, Alicia / González-López, Juan José / García-González, María Del Mar / Mora, Carme / Villalobos, Pilar

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2021  

    Abstract: Background: Recently, Kingella kingae (K. kingae) has been described as the most common agent of skeletal system infections in children 6 months-2 years of age. More exceptional is the clinical presentation in clusters of invasive K. kingae infections. ... ...

    Title translation Primer brote documentado de artritis séptica por Kingella kingae en una guardería de España.
    Abstract Background: Recently, Kingella kingae (K. kingae) has been described as the most common agent of skeletal system infections in children 6 months-2 years of age. More exceptional is the clinical presentation in clusters of invasive K. kingae infections. We describe the investigation of the first outbreak of 3cases of arthritis caused by K. kingae documented in Spain detected in a daycare center in Roses, Girona.
    Patients and methods: In December of 2015 surveillance throat swabs obtained from all attendees from the same class of the index daycare center were assessed to study the prevalence of K. kingae colonization. The sample was composed of 9 toddlers (range: 16-23 months of age). Investigation was performed by culture and K. kingae-specific RT-PCR. Combined amoxicillin-rifampicin prophylaxis was offered to all attendees who were colonized by K. kingae. Following antimicrobial prophylaxis, a new throat swab was taken to confirm bacterial eradication.
    Results: K. kingae was detected by RT-PCR throat swabs in the 3index cases and 5of the 6daycare attendees. Cultures were negative in all cases. After administration of prophylactic antibiotics, 3toddlers were still positive for K. kingae-specific RT-PCR.
    Conclusions: Clusters of invasive K. kingae infections can occur in daycare facilities and closed communities. Increased awareness and use of sensitive detection methods are needed to identify and adequately investigate outbreaks of K. kingae disease. In our experience, the administration of prophylactic antibiotics could result in partial eradication of colonization. No further cases of disease were detected after prophylaxis.
    Language Spanish
    Publishing date 2021-01-04
    Publishing country Spain
    Document type Journal Article
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimc.2020.11.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Epidemiological and clinical characterization of community, healthcare-associated and nosocomial colonization and infection due to carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in Spain.

    Salamanca-Rivera, Elena / Palacios-Baena, Zaira R / Cañada, Javier E / Moure, Zaira / Pérez-Vázquez, María / Calvo-Montes, Jorge / Martínez-Martínez, Luis / Cantón, Rafael / Ruiz Carrascoso, Guillermo / Pitart, Cristina / Navarro, Ferran / Bou, Germán / Mulet, Xavier / González-López, Juan José / Sivianes, Fran / Delgado-Valverde, Mercedes / Pascual, Álvaro / Oteo-Iglesias, Jesús / Rodríguez-Baño, Jesús

    Infection

    2024  

    Abstract: Background: Community-acquired (CA) and healthcare-associated (HCA) infections caused by carbapenemase-producing Enterobacterales (CPE) are not well characterized. The objective was to provide detailed information about the clinical and molecular ... ...

    Abstract Background: Community-acquired (CA) and healthcare-associated (HCA) infections caused by carbapenemase-producing Enterobacterales (CPE) are not well characterized. The objective was to provide detailed information about the clinical and molecular epidemiological features of nosocomial, HCA and CA infections caused by carbapenemase-producing Klebsiella pneumoniae (CP-Kp) and Escherichia coli (CP-Ec).
    Methods: A prospective cohort study was performed in 59 Spanish hospitals from February to March 2019, including the first 10 consecutive patients from whom CP-Kp or CP-Ec were isolated. Patients were stratified according to acquisition type. A multivariate analysis was performed to identify the impact of acquisition type in 30-day mortality.
    Results: Overall, 386 patients were included (363 [94%] with CP-Kp and 23 [6%] CP-Ec); in 296 patients (76.3%), the CPE was causing an infection. Acquisition was CA in 31 (8.0%) patients, HCA in 183 (47.4%) and nosocomial in 172 (48.3%). Among patients with a HCA acquisition, 100 (54.6%) had been previously admitted to hospital and 71 (38.8%) were nursing home residents. Urinary tract infections accounted for 19/23 (82.6%), 89/130 (68.5%) and 42/143 (29.4%) of CA, HCA and nosocomial infections, respectively. Overall, 68 infections (23%) were bacteremia (8.7%, 17.7% and 30.1% of CA, HCA and nosocomial, respectively). Mortality in infections was 28% (13%, 14.6% and 42.7% of CA, HCA and nosocomial, respectively). Nosocomial bloodstream infections were associated with increased odds for mortality (adjusted OR, 4.00; 95%CI 1.21-13.19).
    Conclusions: HCA and CA infections caused by CPE are frequent and clinically significant. This information may be useful for a better understanding of the epidemiology of CPE.
    Language English
    Publishing date 2024-05-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 185104-4
    ISSN 1439-0973 ; 0300-8126 ; 0173-2129
    ISSN (online) 1439-0973
    ISSN 0300-8126 ; 0173-2129
    DOI 10.1007/s15010-024-02267-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Genomic evolution of human respiratory syncytial virus during a decade (2013-2023): bridging the path to monoclonal antibody surveillance.

    Piñana, Maria / González-Sánchez, Alejandra / Andrés, Cristina / Vila, Jorgina / Creus-Costa, Anna / Prats-Méndez, Ignasi / Arnedo-Muñoz, Maria / Saubi, Narcís / Esperalba, Juliana / Rando, Ariadna / Nadal-Baron, Patricia / Quer, Josep / González-López, Juan José / Soler-Palacín, Pere / Martínez-Urtaza, Jaime / Larrosa, Nieves / Pumarola, Tomàs / Antón, Andrés

    The Journal of infection

    2024  Volume 88, Issue 5, Page(s) 106153

    Abstract: Objectives: This study investigated the prevalence, genetic diversity, and evolution of human respiratory syncytial virus (HRSV) in Barcelona from 2013 to 2023.: Methods: Respiratory specimens from patients with RTI suspicion at Hospital Universitari ...

    Abstract Objectives: This study investigated the prevalence, genetic diversity, and evolution of human respiratory syncytial virus (HRSV) in Barcelona from 2013 to 2023.
    Methods: Respiratory specimens from patients with RTI suspicion at Hospital Universitari Vall d'Hebron were collected from October 2013 to May 2023 for laboratory-confirmation of respiratory viruses. Next-generation sequencing was performed in randomly-selected samples with Illumina technology. Phylogenetic analyses of whole genome sequences were performed with BEAST v1.10.4. Signals of selection and evolutionary pressures were inferred by population dynamics and evolutionary analyses. Mutations in major surface proteins were genetic and structurally characterised, emphasizing those within antigenic epitopes.
    Results: Analyzing 139,625 samples, 5.3% were HRSV-positive (3008 HRSV-A, 3882 HRSV-B, 56 HRSV-A and -B, and 495 unsubtyped HRSV), with a higher prevalence observed in the paediatric population. Pandemic-related shifts in seasonal patterns returned to normal in 2022-2023. A total of 198 whole-genome sequences were obtained for HRSV-A (6.6% of the HRSV-A positive samples) belonging to GA2.3.5 lineage. For HRSV-B, 167 samples were sequenced (4.3% of the HRSV-B positive samples), belonging to GB5.0.2, GB5.0.4a and GB5.0.5a. HRSV-B exhibited a higher evolution rate. Post-SARS-CoV-2 pandemic, both subtypes showed increased evolutionary rates and decreased effective population size initially, followed by a sharp increase. Analyses indicated negative selective pressure on HRSV. Mutations in antigenic epitopes, including S276N and M274I in palivizumab-targeted site II, and I206M, Q209R, and S211N in nirsevimab-targeted site Ø, were identified.
    Discussion: Particularly in the context of the large-scale use in 2023-2024 season of nirsevimab, continuous epidemiological and genomic surveillance is crucial.
    MeSH term(s) Humans ; Respiratory Syncytial Virus, Human/genetics ; Respiratory Syncytial Virus, Human/immunology ; Respiratory Syncytial Virus, Human/classification ; Respiratory Syncytial Virus Infections/epidemiology ; Respiratory Syncytial Virus Infections/virology ; Phylogeny ; Child, Preschool ; Child ; Male ; Infant ; Evolution, Molecular ; Female ; Genome, Viral ; Middle Aged ; Spain/epidemiology ; Adolescent ; Adult ; Genetic Variation ; Antibodies, Monoclonal/immunology ; Aged ; Young Adult ; Mutation ; Whole Genome Sequencing ; Antibodies, Viral/blood ; Prevalence ; High-Throughput Nucleotide Sequencing ; Infant, Newborn
    Chemical Substances Antibodies, Monoclonal ; Antibodies, Viral
    Language English
    Publishing date 2024-04-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2024.106153
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Increasing trend of antimicrobial resistance in Shigella associated with MSM transmission in Barcelona, 2020-21: outbreak of XRD Shigella sonnei and dissemination of ESBL-producing Shigella flexneri.

    Moreno-Mingorance, Albert / Mir-Cros, Alba / Goterris, Lidia / Rodriguez-Garrido, Virginia / Sulleiro, Elena / Barberà, M Jesús / Alberny, Mireia / Hoyos-Mallecot, Yannick / Descalzo, Vicente / Bravo, Albert / Roca-Grande, Josep / Viñado, Belén / Pumarola, Tomàs / Larrosa, M Nieves / González-López, Juan José

    The Journal of antimicrobial chemotherapy

    2023  Volume 78, Issue 4, Page(s) 975–982

    Abstract: Background: Several countries have recently reported the detection of ESBL-producing Shigella sonnei associated with transmission among MSM. In a previous study by our group, 2.8% of Shigella spp. obtained from MSM in Barcelona between 2015 and 2019 ... ...

    Abstract Background: Several countries have recently reported the detection of ESBL-producing Shigella sonnei associated with transmission among MSM. In a previous study by our group, 2.8% of Shigella spp. obtained from MSM in Barcelona between 2015 and 2019 were ESBL producers.
    Objectives: To describe and characterize the emerging ESBL-producing Shigella spp. associated with sexual transmission among MSM detected from 2020 to 2021 in Barcelona, elucidating their connectivity with contemporaneous ESBL-producing Shigella spp. from other countries.
    Results: From 2020 to 2021, we identified that among MSM, 68% of S. sonnei were XDR harbouring blaCTX-M-27 and 14% of Shigella flexneri were MDR harbouring blaCTX-M-27. WGS analysis showed that the ESBL-producing S. sonnei were part of a monophyletic cluster, which included isolates responsible for the prolonged outbreak occurring in the UK. Our data also reveal the first emergence and clonal dissemination of ESBL-producing and fluoroquinolone-resistant S. flexneri 2a among MSM.
    Conclusions: We report an increasing trend of antimicrobial resistance in Shigella spp. among MSM in Barcelona since 2021, mainly as a consequence of the dissemination of XDR ESBL-producing S. sonnei, previously reported in the UK. These results highlight the importance of international collaborative surveillance of MDR/XDR S. sonnei and S. flexneri for rapid identification of their emergence and the prevention of the transmission of these pathogens.
    MeSH term(s) Male ; Humans ; Shigella flexneri ; Shigella sonnei ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Dysentery, Bacillary/epidemiology ; Dysentery, Bacillary/drug therapy ; Homosexuality, Male ; Drug Resistance, Bacterial ; Microbial Sensitivity Tests ; Sexual and Gender Minorities ; Shigella ; Disease Outbreaks
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-02-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkad031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Ceftazidime-Avibactam plus Aztreonam for the Treatment of Infections by VIM-Type-Producing Gram-Negative Bacteria.

    Sempere, Abiu / Viñado, Belén / Los-Arcos, Ibai / Campany, David / Larrosa, Nieves / Fernández-Hidalgo, Nuria / Rodríguez-Pardo, Dolors / González-López, Juan José / Nuvials, Xavier / Almirante, Benito / Escolà-Vergé, Laura

    Antimicrobial agents and chemotherapy

    2022  Volume 66, Issue 10, Page(s) e0075122

    Abstract: This is a retrospective single-center study of 24 patients who received ceftazidime-avibactam plus aztreonam (CZA/ATM) for the treatment of VIM-type-producing Gram-negative bacillus (GNB) infections. The bacteria isolated ... ...

    Abstract This is a retrospective single-center study of 24 patients who received ceftazidime-avibactam plus aztreonam (CZA/ATM) for the treatment of VIM-type-producing Gram-negative bacillus (GNB) infections. The bacteria isolated were
    MeSH term(s) Humans ; Aztreonam/therapeutic use ; Retrospective Studies ; beta-Lactamases ; Microbial Sensitivity Tests ; Anti-Bacterial Agents/therapeutic use ; Azabicyclo Compounds/therapeutic use ; Ceftazidime/therapeutic use ; Gram-Negative Bacteria ; Drug Combinations
    Chemical Substances Aztreonam (G2B4VE5GH8) ; avibactam, ceftazidime drug combination ; beta-Lactamases (EC 3.5.2.6) ; Anti-Bacterial Agents ; Azabicyclo Compounds ; Ceftazidime (9M416Z9QNR) ; Drug Combinations
    Language English
    Publishing date 2022-09-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/aac.00751-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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