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  1. Article ; Online: Social Participation Strategies and Resilience in Mexican Population Affected by the 2017 Earthquakes.

    Abeldaño Zuñiga, Roberto Ariel / González Villoria, Ruth Ana María

    Disaster medicine and public health preparedness

    2019  Volume 14, Issue 3, Page(s) 335–342

    Abstract: Objective: To describe social participation strategies and resilience in the people affected by the 2017 earthquakes in Mexico.: Methods: A cross-sectional study was carried out with 1504 participants from Mexico City, State of Mexico, Oaxaca, ... ...

    Abstract Objective: To describe social participation strategies and resilience in the people affected by the 2017 earthquakes in Mexico.
    Methods: A cross-sectional study was carried out with 1504 participants from Mexico City, State of Mexico, Oaxaca, Chiapas, Puebla, and Morelos in November and December 2017. A nonprobabilistic convenience sampling method was used to recruit voluntary participants who met the inclusion criteria: age 18 or over and residents in damaged states at the time of the earthquakes. Postearthquake social participation strategies were assessed with the formats used in the postearthquake Chilean survey in 2010. The Spanish-validated version of the resilience scale RS-14 was applied for measuring resilience in the Mexican population.
    Results: The most frequent social participation strategies were related to emotional support and aid supplying water, food, and clothing. The highest resilience was observed in the state of Oaxaca and in Mexico City. Men, people age 40 or over, and people who defined themselves as indigenous were the most resilient.
    Conclusions: Factors related to resilience were male gender, age over 40, did not participate in activities of help to the community, no household damage, and belonging to an indigenous community.
    MeSH term(s) Adult ; Cross-Sectional Studies ; Earthquakes/statistics & numerical data ; Female ; Humans ; Logistic Models ; Male ; Mexico ; Middle Aged ; Resilience, Psychological ; Social Participation/psychology ; Surveys and Questionnaires
    Language English
    Publishing date 2019-08-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2375268-3
    ISSN 1938-744X ; 1935-7893
    ISSN (online) 1938-744X
    ISSN 1935-7893
    DOI 10.1017/dmp.2019.59
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clinical effectiveness of drugs in hospitalized patients with COVID-19: a systematic review and meta-analysis.

    Abeldaño Zuñiga, Roberto Ariel / Coca, Silvia Mercedes / Abeldaño, Giuliana Florencia / González-Villoria, Ruth Ana María

    Therapeutic advances in respiratory disease

    2021  Volume 15, Page(s) 17534666211007214

    Abstract: The aim was to assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection. We conducted a systematic review of randomized clinical trials assessing treatment with remdesivir, chloroquine, hydroxychloroquine, ... ...

    Abstract The aim was to assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection. We conducted a systematic review of randomized clinical trials assessing treatment with remdesivir, chloroquine, hydroxychloroquine, lopinavir, ritonavir, dexamethasone, and convalescent plasma, for hospitalized patients with a diagnosis of SARS-CoV-2 infection. The outcomes were mortality, clinical improvement, duration of ventilation, duration of oxygen support, duration of hospitalization, virological clearance, and severe adverse events. A total of 48 studies were retrieved from the databases. Eleven articles were finally included in the data extraction and qualitative synthesis of results. The meta-analysis suggests a benefit of dexamethasone
    MeSH term(s) Antiviral Agents/therapeutic use ; COVID-19/drug therapy ; Hospitalization ; Humans ; Treatment Outcome
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-03-23
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2476459-0
    ISSN 1753-4666 ; 1753-4658
    ISSN (online) 1753-4666
    ISSN 1753-4658
    DOI 10.1177/17534666211007214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical effectiveness of convalescent plasma in hospitalized patients with COVID-19: a systematic review and meta-analysis.

    Abeldaño Zuñiga, Roberto Ariel / González-Villoria, Ruth Ana María / Elizondo, María Vanesa / Osorio, Anel Yaneli Nicolás / Martínez, David Gómez / Coca, Silvia Mercedes

    Therapeutic advances in respiratory disease

    2021  Volume 15, Page(s) 17534666211028077

    Abstract: Aims: Given the variability of previously reported results, this systematic review aims to determine the clinical effectiveness of convalescent plasma employed in the treatment of hospitalized patients diagnosed with COVID-19.: Methods: We conducted ... ...

    Abstract Aims: Given the variability of previously reported results, this systematic review aims to determine the clinical effectiveness of convalescent plasma employed in the treatment of hospitalized patients diagnosed with COVID-19.
    Methods: We conducted a systematic review of controlled clinical trials assessing treatment with convalescent plasma for hospitalized patients diagnosed with SARS-CoV-2 infection. The outcomes were mortality, clinical improvement, and ventilation requirement.
    Results: A total of 51 studies were retrieved from the databases. Five articles were finally included in the data extraction and qualitative and quantitative synthesis of results. The overall risk of bias in the reviewed articles was established at low-risk only in two trials. The meta-analysis suggests that there is no benefit of convalescent plasma compared with standard care or placebo in reducing the overall mortality and the ventilation requirement. However, there could be a benefit for the clinical improvement in patients treated with plasma.
    Conclusion: Current results led to assume that the convalescent plasma transfusion cannot reduce the mortality or ventilation requirement in hospitalized patients diagnosed with SARS-CoV-2 infection. More controlled clinical trials conducted with methodologies that ensure a low risk of bias are still needed.
    MeSH term(s) COVID-19/diagnosis ; COVID-19/mortality ; COVID-19/therapy ; Hospital Mortality ; Hospitalization ; Humans ; Immunization, Passive/adverse effects ; Immunization, Passive/mortality ; Recovery of Function ; Respiration, Artificial ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2021-06-30
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2476459-0
    ISSN 1753-4666 ; 1753-4658
    ISSN (online) 1753-4666
    ISSN 1753-4658
    DOI 10.1177/17534666211028077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Clinical effectiveness of drugs in hospitalized patients with COVID-19 infection: a systematic review and meta-analysis.

    Abeldano Zuniga, Roberto Ariel / Coca, Silvia / Abeldano, Giuliana / Gonzalez Villoria, Ruth Ana Maria

    medRxiv

    Abstract: Objective. The aim was to assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection. Method. We conducted a systematic review of randomized clinical trials assessing treatment with remdesivir, chloroquine, ... ...

    Abstract Objective. The aim was to assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection. Method. We conducted a systematic review of randomized clinical trials assessing treatment with remdesivir, chloroquine, hydroxychloroquine, lopinavir, ritonavir, dexamethasone, and convalescent plasma, for hospitalized patients with a diagnosis of SARS-CoV-2 infection. The outcomes were mortality, clinical improvement, duration of ventilation, duration of oxygen support, duration of hospitalization), virological clearance, and severe adverse events. Results. A total of 48 studies were retrieved from the databases. Ten articles were finally included in the data extraction and qualitative synthesis of results. The meta-analysis suggests a benefit of dexamethasone versus standard care in the reduction of risk of mortality at day 28; and the clinical improvement at days 14 and 28 in patients treated with remdesivir. Conclusions. Dexamethasone would have a better result in hospitalized patients, especially in low-resources settings. Significance of results. The analysis of the main treatments proposed for hospitalized patients is of vital importance to reduce mortality in low-income countries; since the COVID-19 pandemic had an economic impact worldwide with the loss of jobs and economic decline in countries with scarce resources. Keywords: Drugs; Antivirals; Clinical improvement; Mortality; COVID-19; SARS-CoV2.
    Keywords covid19
    Language English
    Publishing date 2020-09-13
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2020.09.11.20193011
    Database COVID19

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  5. Article ; Online: Clinical effectiveness of convalescent plasma in hospitalized patients with COVID-19: a systematic review and meta-analysis

    Abeldano Zuniga, Roberto Ariel / Gonzalez Villoria, Ruth Ana Maria / Elizondo, Maria Vanesa / Nicolas Osorio, Anel Yaneli / Coca, Silvia Mercedes

    medRxiv

    Abstract: Given the variability of previously reported results, this systematic review aims to determine the clinical effectiveness of convalescent plasma employed in the treatment of hospitalized patients with diagnosis of COVID-19. We conducted a systematic ... ...

    Abstract Given the variability of previously reported results, this systematic review aims to determine the clinical effectiveness of convalescent plasma employed in the treatment of hospitalized patients with diagnosis of COVID-19. We conducted a systematic review of controlled clinical trials assessing treatment with convalescent plasma for hospitalized patients with a diagnosis of SARS-CoV-2 infection. The outcomes were mortality, clinical improvement, and ventilation requirement. A total of 50 studies were retrieved from the databases. Four articles were finally included in the data extraction, qualitative and quantitative synthesis of results. The meta-analysis suggests that there is no benefit of convalescent plasma compared to standard care or placebo in the reduction of the overall mortality and in the ventilation requirement; but there could be a benefit for the clinical improvement in patients treated with plasma. We can conclude that the convalescent plasma transfusion cannot reduce the mortality or ventilation requirement in hospitalized patients diagnosed with SARS-CoV-2 infection. More controlled clinical trials conducted with methodologies that ensure a low risk of bias are still needed.
    Keywords covid19
    Language English
    Publishing date 2021-01-22
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2021.01.16.21249956
    Database COVID19

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