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  1. Book ; Online: Estrategias de relaciones laborales en empresas multinacionales en Argentina y Brasil 2008-2019

    Senén González, Cecilia

    un abordaje configuracionista

    2022  

    Keywords Personnel & human resources management ; Labour economics ; History of specific companies / corporate history ; Management & Organizational Behavior ; Labor & Employment Relations ; Business
    Language Spanish
    Size 1 Online-Ressource
    Publisher CLACSO
    Document type Book ; Online
    Note Spanish
    HBZ-ID HT030610445
    ISBN 9789502919423 ; 9502919424
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Health Literacy

    Miguel Rios-González, Carlos

    Advances and Trends

    2023  

    Keywords Health psychology ; chronic diseases ; ehealth ; mhealth ; organ donation ; decentralization ; health communication
    Language English
    Size 1 electronic resource (102 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030380874
    ISBN 9781803563107 ; 1803563109
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Transgender Health

    Miguel Rios-González, Carlos

    Advances and New Perspectives

    2022  

    Keywords Health psychology ; Medicine: general issues
    Language English
    Size 1 electronic resource (134 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030378564
    ISBN 9781803552996 ; 1803552999
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Building Human-Like Artificial Agents: A General Cognitive Algorithm for Emulating Human Decision-Making in Dynamic Environments.

    Gonzalez, Cleotilde

    Perspectives on psychological science : a journal of the Association for Psychological Science

    2023  , Page(s) 17456916231196766

    Abstract: One of the early goals of artificial intelligence (AI) was to create algorithms that exhibited behavior indistinguishable from human behavior (i.e., human-like behavior). Today, AI has diverged, often aiming to excel in tasks inspired by human ... ...

    Abstract One of the early goals of artificial intelligence (AI) was to create algorithms that exhibited behavior indistinguishable from human behavior (i.e., human-like behavior). Today, AI has diverged, often aiming to excel in tasks inspired by human capabilities and outperform humans, rather than replicating human cogntion and action. In this paper, I explore the overarching question of whether computational algorithms have achieved this initial goal of AI. I focus on dynamic decision-making, approaching the question from the perspective of computational cognitive science. I present a general cognitive algorithm that intends to emulate human decision-making in dynamic environments, as defined in instance-based learning theory (IBLT). I use the cognitive steps proposed in IBLT to organize and discuss current evidence that supports some of the human-likeness of the decision-making mechanisms. I also highlight the significant gaps in research that are required to improve current models and to create higher fidelity in computational algorithms to represent human decision processes. I conclude with concrete steps toward advancing the construction of algorithms that exhibit human-like behavior with the ultimate goal of supporting human dynamic decision-making.
    Language English
    Publishing date 2023-10-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2224911-4
    ISSN 1745-6924 ; 1745-6916
    ISSN (online) 1745-6924
    ISSN 1745-6916
    DOI 10.1177/17456916231196766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Injuries around the upper limb. Latest Spanish experience.

    Olaya-González, Carlos

    Injury

    2024  Volume 54 Suppl 7, Page(s) 110809

    MeSH term(s) Humans ; Upper Extremity/surgery ; Upper Extremity/injuries ; Arm Injuries
    Language English
    Publishing date 2024-01-13
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2023.05.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 778: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 10: Show issues

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  6. Article ; Online: Pediatric immune deficiencies: current treatment approaches.

    Gonzalez, Corina

    Current opinion in pediatrics

    2022  Volume 34, Issue 1, Page(s) 61–70

    Abstract: Purpose of review: To summarize the currently available definitive therapies for patients with inborn errors of immunity (IEIs) with a strong focus on recent advances in allogeneic hematopoietic cell transplantation (HCT) and gene therapy, including the ...

    Abstract Purpose of review: To summarize the currently available definitive therapies for patients with inborn errors of immunity (IEIs) with a strong focus on recent advances in allogeneic hematopoietic cell transplantation (HCT) and gene therapy, including the use of alternative donors, graft manipulation techniques, less toxic approaches for pretransplant conditioning and gene transfer using autologous hematopoietic stem cells.
    Recent findings: In the absence of a matched sibling or a matched related donor, therapeutic alternatives for patients with IEIs include alternative donor transplantation or autologous gene therapy, which is only available for selected IEIs. In recent years, several groups have published their experience with haploidentical hematopoietic cell transplantation (HHCT) using different T-cell depletion strategies. Overall survival and event free survival results, although variable among centers, are encouraging. Preliminary results from autologous gene therapy trials with safer vectors and low-dose busulfan conditioning have shown reproducible and successful results. Both strategies have become valid therapeutic options for patients with IEIs. A new promising and less toxic conditioning regimen strategy is also discussed.
    Summary: Definitive therapies for IEIs with HCT and gene therapy are in stage of evolution, not only to refine their efficacy and safety but also their reach to a larger number of patients.
    MeSH term(s) Child ; Graft vs Host Disease/etiology ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Immunologic Deficiency Syndromes/genetics ; Immunologic Deficiency Syndromes/therapy ; Siblings ; Transplantation Conditioning/methods ; Transplantation, Homologous ; Treatment Outcome
    Language English
    Publishing date 2022-03-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1049374-8
    ISSN 1531-698X ; 1040-8703
    ISSN (online) 1531-698X
    ISSN 1040-8703
    DOI 10.1097/MOP.0000000000001092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3049: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Additively-manufactured Mg wire-reinforced PLDL-matrix composites for biomedical applications.

    Thompson, C / González, C / LLorca, J

    Journal of the mechanical behavior of biomedical materials

    2024  Volume 153, Page(s) 106496

    Abstract: Coupons of a medical grade PLDL polymer matrix uniaxially reinforced with a 15% volume fraction of Mg wires have been manufactured by fused filament fabrication for the first time. Two different types of Mg wires, without and with a surface treatment by ... ...

    Abstract Coupons of a medical grade PLDL polymer matrix uniaxially reinforced with a 15% volume fraction of Mg wires have been manufactured by fused filament fabrication for the first time. Two different types of Mg wires, without and with a surface treatment by plasma electrolytic oxidation were used. Both composite materials were subjected to degradation in phosphate buffer solution over a 3-week period, and their degradation and deformation micromechanisms were analysed in detail. Additionally, the materials were subjected to extensive mechanical testing under various loading conditions, and the interface strength was also analysed. It was found that the presence of the Mg wires improves the mechanical behaviour and accelerates the corrosion rate of the composite with respect that of the polymer matrix and these properties can be further tailored through the surface-modification of Mg wires by plasma electrolytic oxidation. The additive manufacturing strategy presented opens the path to fabricate multimaterial implants and scaffolds with complex shape and tailored properties provided by biodegradable polymers reinforced with either Mg and Zn particles and/or wires.
    MeSH term(s) Polymers ; Prostheses and Implants ; Tissue Scaffolds
    Chemical Substances Polymers
    Language English
    Publishing date 2024-03-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2024.106496
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: Costing Improved Water Supply Systems for Low-income Communities : A Practical Manual

    Gonzalez, Cristian / Carlevaro, Fabrizio

    2015  

    Keywords Environmental science, engineering & technology ; Industrial applications of scientific research & technological innovation ; Technology & Engineering ; Environmental ; General ; Science ; Applied Sciences ; Environmental Science (see Also Chemistry ; Environmental)
    Size 1 Online-Ressource
    Publisher IWA Publishing
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021030718
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  9. Article ; Online: Learning and Dynamic Decision Making.

    Gonzalez, Cleotilde

    Topics in cognitive science

    2021  Volume 14, Issue 1, Page(s) 14–30

    Abstract: Humans make decisions in dynamic environments (increasingly complex, highly uncertain, and changing situations) by searching for potential alternatives sequentially over time, to determine the best option at a precise moment. Surprisingly, the field of ... ...

    Abstract Humans make decisions in dynamic environments (increasingly complex, highly uncertain, and changing situations) by searching for potential alternatives sequentially over time, to determine the best option at a precise moment. Surprisingly, the field of behavioral decision making has little to offer in terms of theoretical principles and practical guidelines on how people make decisions in dynamic situations. My research program aims to fill in this gap by developing theoretical understandings of decision processes as well as practical demonstrations of how these theoretical developments can improve human dynamic decision making. Throughout my research career, I have helped create, test, and improve a general theory of dynamic decision making, instance-based learning theory, IBLT. The methods I have used to contribute to IBLT are (1) laboratory experiments that rely on dynamic games in which humans make choices over time and space, individually and in teams, and from which we extrapolate robust phenomena and behavioral insights; and (2) computational, actionable cognitive models, which specify the decision-making process and the cognitive mechanisms involved into a computational algorithm. The combination of these methods spawned novel applications in areas such as cybersecurity, phishing, climate change, and human-machine interactions. In this paper, I will take you through my own intellectual exploratory experience of computational modeling of human decision processes, and how the integration of experimental work and cognitive modeling helped in discovering and uncovering the field of dynamic decision making.
    MeSH term(s) Decision Making ; Humans ; Learning ; Uncertainty
    Language English
    Publishing date 2021-11-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2482883-X
    ISSN 1756-8765 ; 1756-8757
    ISSN (online) 1756-8765
    ISSN 1756-8757
    DOI 10.1111/tops.12581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Addressing the Mechanical Interaction Between Cancer-Associated Fibroblasts and Cancer Cells by Laser Ablation.

    Perez-Gonzalez, Carlos / Barbazán, Jorge

    Methods in molecular biology (Clifton, N.J.)

    2024  Volume 2764, Page(s) 179–203

    Abstract: Cells within a tumor interact by generating, transmitting, and sensing mechanical forces. Among all the cells of the tumor microenvironment, cancer-associated fibroblasts (CAFs) are a paradigmatic example of mechanical communication. In different steps ... ...

    Abstract Cells within a tumor interact by generating, transmitting, and sensing mechanical forces. Among all the cells of the tumor microenvironment, cancer-associated fibroblasts (CAFs) are a paradigmatic example of mechanical communication. In different steps of tumor progression, CAFs pull and push on cancer cells, regulating cancer cell migration, invasion, compartmentalization, and signaling. There is thus an increasing need to experimentally address mechanical interactions within a tumor. A common technique to measure these interactions is laser ablation. Cutting a tissue region with a high-power laser triggers a sudden tissue displacement whose direction and magnitude reveal the local mechanical stresses. In this chapter, we provide a detailed protocol to perform laser ablations in vitro and ex vivo. First, we describe how to prepare cocultures of primary CAFs and cancer cells and tumor explants. Then, we explain how to perform laser ablations in these two systems and how to analyze the induced tissue displacements using particle image velocimetry (PIV). Overall, we provide a workflow to perform, analyze, and interpret laser ablations to explore tumor mechanical interactions.
    MeSH term(s) Humans ; Cancer-Associated Fibroblasts/pathology ; Fibroblasts/pathology ; Neoplasms/pathology ; Coculture Techniques ; Laser Therapy ; Tumor Microenvironment ; Cell Line, Tumor ; Cell Movement
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3674-9_13
    Database MEDical Literature Analysis and Retrieval System OnLINE

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