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  1. Article ; Online: Practice of Telehealth in Otolaryngology: A Scoping Review in the Era of COVID-19.

    Gonzalez, Joseph N / Axiotakis, Lucas G / Yu, Victoria X / Gudis, David A / Overdevest, Jonathan B

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2021  Volume 166, Issue 3, Page(s) 417–424

    Abstract: Objective: The COVID-19 pandemic has spurred widespread adoption and advancement in telehealth activities, representing a marked change in otolaryngology practice patterns. The present study undertakes a scoping review of research focused on telehealth ... ...

    Abstract Objective: The COVID-19 pandemic has spurred widespread adoption and advancement in telehealth activities, representing a marked change in otolaryngology practice patterns. The present study undertakes a scoping review of research focused on telehealth in otolaryngology (teleotolaryngology) to identify key themes and commonly utilized outcome measures that will assist future development in this growing field.
    Data sources: PubMed, Embase, and Cochrane databases and reference review.
    Review methods: Per guidelines of the PRISMA Extension for Scoping Reviews, we performed database queries using a comprehensive search strategy developed in collaboration with research librarians at the Columbia University Irving Medical Center. We identified 596 unique references to undergo title and abstract review by 2 independent reviewers, leaving 439 studies for full-text review.
    Results: We included 285 studies for extraction of notable findings, leaving 262 unique studies after accounting for content overlap. We identified core outcome measures, including patient and provider satisfaction, costs and benefits, quality of care, feasibility, and access to care. Publication volume increased markedly over time, though only 4% of studies incorporated randomized study group assignment. Using an iterative approach to thematic development, we organized article content across 5 main themes: (1) exploration of teleotolaryngology evolution, (2) role in virtual clinical encounters, (3) applications in interdisciplinary care and educational initiatives, (4) emerging and innovative technologies, and (5) barriers to implementation.
    Conclusion: This scoping review of teleotolaryngology documents its evolution and identifies current use cases, limitations, and emerging applications, providing a foundation from which to build future studies, inform policy decision making, and facilitate implementation where appropriate.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Delivery of Health Care ; Humans ; Otolaryngology ; Outcome Assessment, Health Care ; Telemedicine
    Language English
    Publishing date 2021-05-18
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1177/01945998211013751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Antibiotic adverse effects in pediatric acute rhinosinusitis: Systematic review and meta-analysis.

    Axiotakis, Lucas G / Szeto, Betsy / Gonzalez, Joseph N / Caruana, Francesco F / Gudis, David A / Overdevest, Jonathan B

    International journal of pediatric otorhinolaryngology

    2022  Volume 156, Page(s) 111064

    Abstract: Background: Pediatric acute bacterial rhinosinusitis (ABRS) is often treated with oral antibiotics, with limited insight into adverse effects (AEs) across drug classes. In this systematic review and meta-analysis, we characterize AE incidence associated ...

    Abstract Background: Pediatric acute bacterial rhinosinusitis (ABRS) is often treated with oral antibiotics, with limited insight into adverse effects (AEs) across drug classes. In this systematic review and meta-analysis, we characterize AE incidence associated with oral antibiotics in these patients.
    Methodology/principal: We searched PubMed and Embase for English-language articles published from 1985 to September 2020 reporting AEs of oral antibiotic therapy for ABRS patients aged 0-18 years. Six-hundred and sixty-six articles underwent title and abstract screening, identifying 154 articles for full-length review.
    Results: Eleven articles were included, most of which reported individual and aggregate AE incidences. Amoxicillin/clavulanate, amoxicillin, cephalosporin/carbacephem, and placebo groups were identified. Random-effects meta-analysis of prospective groups identified appreciable incidences of diarrhea and abdominal pain, and low incidence of rash, for amoxicillin-clavulanate and amoxicillin. All antibiotics as well as placebo were associated with non-zero overall AE incidence. Children receiving antibiotics were about twice as likely to incur any AE during treatment in placebo-controlled studies, though this association was not significant. High heterogeneity limited most point estimates, with risk of bias, typically in outcomes measurement, detected in most studies.
    Conclusions: Reporting of AEs associated with oral antibiotic use in pediatric ABRS is limited in current literature. Adverse effects are non-negligible, but may not significantly exceed placebo.
    MeSH term(s) Acute Disease ; Amoxicillin/adverse effects ; Amoxicillin-Potassium Clavulanate Combination/adverse effects ; Anti-Bacterial Agents/adverse effects ; Child ; Humans ; Prospective Studies ; Sinusitis/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Amoxicillin-Potassium Clavulanate Combination (74469-00-4) ; Amoxicillin (804826J2HU)
    Language English
    Publishing date 2022-02-16
    Publishing country Ireland
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2022.111064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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