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  1. Article ; Online: Pulmonary infections in the returning traveler.

    Norman, Francesca F / Gonzalez-Sanz, Marta

    Current opinion in pulmonary medicine

    2024  Volume 30, Issue 3, Page(s) 243–251

    Abstract: Purpose of review: The recent COVID-19 pandemic has shaped the epidemiology of other infectious diseases globally. International tourist arrivals are increasing and recovering to prepandemic levels. This review focuses on respiratory infections in ... ...

    Abstract Purpose of review: The recent COVID-19 pandemic has shaped the epidemiology of other infectious diseases globally. International tourist arrivals are increasing and recovering to prepandemic levels. This review focuses on respiratory infections in travelers, highlighting the characteristics of the main imported viral, bacterial, fungal, and parasitic infections with pulmonary involvement.
    Recent findings: A recent systematic review estimated a prevalence of respiratory symptoms in travelers of around 35%, increasing to nearly 65% in the context of mass gatherings. Common viral and bacterial pathogens account for the majority of respiratory infections with an identified cause; however, recent data focus on the need for surveillance of emerging infections such as MERS-CoV, henipaviruses and multidrug resistant bacteria, which may be spread through travel. Fungal and parasitic respiratory infections are less common, and acquisition is usually associated with specific risk factors or exposure in endemic areas. Special risk groups, such as immunocompromised travelers, may be particularly vulnerable, presenting with severe disease or reactivation of latent infections.
    Summary: The next significant international epidemic could involve another new infectious agent causing respiratory disease and spreading via mobile populations. Official protocols should be adhered to, and public health interventions implemented for effective control. Continued and globally coordinated investments in research for new vaccines, therapeutic agents, disease modeling, and digital tracking strategies are essential.
    MeSH term(s) Humans ; Pandemics ; Travel ; Pneumonia ; Risk Factors ; Respiratory Tract Infections
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1285505-4
    ISSN 1531-6971 ; 1070-5287 ; 1078-1641
    ISSN (online) 1531-6971
    ISSN 1070-5287 ; 1078-1641
    DOI 10.1097/MCP.0000000000001051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Updates on Malaria Epidemiology and Prevention Strategies.

    González-Sanz, Marta / Berzosa, Pedro / Norman, Francesca F

    Current infectious disease reports

    2023  , Page(s) 1–9

    Abstract: Purpose of review: The objective of this review was to provide an update on recent malaria epidemiology, both globally and in non-endemic areas, to identify the current distribution and repercussions of genetically diverse Plasmodium species and ... ...

    Abstract Purpose of review: The objective of this review was to provide an update on recent malaria epidemiology, both globally and in non-endemic areas, to identify the current distribution and repercussions of genetically diverse Plasmodium species and summarize recently implemented intervention and prevention tools.
    Recent findings: Notable changes in malaria epidemiology have occurred in recent years, with an increase in the number of total cases and deaths globally during 2020-2021, in part attributed to the COVID-19 pandemic. The emergence of artemisinin-resistant species in new areas and the expanding distribution of parasites harbouring deletions of the pfhrp2/3 genes have been concerning. New strategies to curb the burden of this infection, such as vaccination, have been implemented in certain endemic areas and their performance is currently being evaluated.
    Summary: Inadequate control of malaria in endemic regions may have an effect on imported malaria and measures to prevent re-establishment of transmission in malaria-free areas are essential. Enhanced surveillance and investigation of Plasmodium spp. genetic variations will contribute to the successful diagnosis and treatment of malaria in future. Novel strategies for an integrated One Health approach to malaria control should also be strengthened.
    Language English
    Publishing date 2023-06-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2019948-X
    ISSN 1534-3146 ; 1523-3847
    ISSN (online) 1534-3146
    ISSN 1523-3847
    DOI 10.1007/s11908-023-00805-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chagas Disease in Europe.

    Gonzalez-Sanz, Marta / Crespillo-Andújar, Clara / Chamorro-Tojeiro, Sandra / Monge-Maillo, Begoña / Perez-Molina, Jose A / Norman, Francesca F

    Tropical medicine and infectious disease

    2023  Volume 8, Issue 12

    Abstract: Chagas disease is currently present in many non-endemic countries and remains a neglected tropical disease globally. A review of the literature identified significant gaps and scarcity of updated information from European countries, with most studies ... ...

    Abstract Chagas disease is currently present in many non-endemic countries and remains a neglected tropical disease globally. A review of the literature identified significant gaps and scarcity of updated information from European countries, with most studies reporting data from Spain and Italy. The index of underdiagnosis may be as high as 70%, affecting mainly females of child-bearing age. Standardized screening of fertile, non-pregnant, women from endemic countries and subsequent treatment is considered an essential strategy to control transmission and prevent new cases, yet no uniform legislation for screening risk groups exists. There is heterogeneity in Europe in terms of preventive strategies to avoid transfusion-related transmission of Chagas disease, not necessarily in line with the European directives, with some countries conducting systematic screening for
    Language English
    Publishing date 2023-12-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed8120513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Bilateral pulmonary infiltrates in a traveller from Saudi Arabia with probable electronic cigarette or vaping associated lung injury (EVALI).

    Norman, Francesca F / Diaz, Jorge / Martin-Davila, Pilar / Tato, Marta / García-San Miguel, Lucía / Gil, Elisa / Casas, Inmaculada / Gonzalez-Sanz, Marta

    Journal of travel medicine

    2024  Volume 30, Issue 8

    MeSH term(s) Humans ; Lung Injury/etiology ; Electronic Nicotine Delivery Systems ; Vaping/adverse effects ; Saudi Arabia
    Language English
    Publishing date 2024-04-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taad133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Haemoglobinopathies in mobile populations from sub-Saharan Africa.

    Norman, Francesca F / Gonzalez-Sanz, Marta / Gullón-Peña, Beatriz / Chamorro-Tojeiro, Sandra / Rosas, Marta / Crespillo-Andujar, Clara / Monge-Maillo, Begoña / Comeche, Belen / Corbacho-Loarte, Maria-Dolores / Arcas, Cristina / Peña, Ignacio / Tenorio, Maria C / Lopez-Vélez, Rogelio / Pérez-Molina, Jose A

    Journal of travel medicine

    2023  Volume 30, Issue 7

    MeSH term(s) Humans ; Hemoglobinopathies/diagnosis ; Hemoglobinopathies/epidemiology ; Africa South of the Sahara/epidemiology
    Language English
    Publishing date 2023-08-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taad115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Chagas disease in the United Kingdom: A review of cases at the Hospital for Tropical Diseases London 1995-2018. The current state of detection of Chagas disease in the UK.

    González Sanz, Marta / De Sario, Valentina / García-Mingo, Ana / Nolder, Debbie / Dawood, Naghum / Álvarez-Martínez, Míriam J / Daly, Rosemarie / Lowe, Patricia / Yacoub, Sophie / Moore, David Aj / Chiodini, Peter L

    Travel medicine and infectious disease

    2020  Volume 36, Page(s) 101760

    Abstract: Background: Chagas disease (CD), is a parasitic disease endemic in Latin America. Presentation in non-endemic areas is either in the asymptomatic indeterminate phase or the chronic phase with cardiac and/or gastrointestinal complications.: Methods: ... ...

    Abstract Background: Chagas disease (CD), is a parasitic disease endemic in Latin America. Presentation in non-endemic areas is either in the asymptomatic indeterminate phase or the chronic phase with cardiac and/or gastrointestinal complications.
    Methods: The Hospital for Tropical Diseases (HTD) based in central London, provides tertiary care for the management of CD. We reviewed all cases managed at this centre between 1995 and 2018.
    Results: Sixty patients with serologically proven CD were identified. Most were female (70%), with a median age at diagnosis of 41 years. Three quarters of the patients were originally from Bolivia. 62% of all patients were referred to the HTD by their GP. Nearly half of the patients were asymptomatic (47%). Twelve patients had signs of cardiac involvement secondary to CD. Evidence of gastrointestinal damage was established in three patients. Treatment was provided at HTD for 31 patients (47%). Most patients (29) received benznidazole, five of them did not tolerate the course and were switched to nifurtimox. Of the seven patients receiving this second line drug, five completed treatment, whilst two interrupted it due to side effects.
    Conclusions: Despite the UK health system having all the resources required to diagnose, treat and follow up cases, there is lack of awareness of CD, such that the vast majority of cases remain undiagnosed and therefore do not receive treatment. We propose key interventions to improve the detection and management of this condition in the UK, especially in pregnant women and neonates.
    MeSH term(s) Bolivia ; Chagas Disease ; Female ; Hospitals ; Humans ; Infant, Newborn ; Latin America ; London ; Pregnancy ; United Kingdom/epidemiology
    Language English
    Publishing date 2020-06-01
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2020.101760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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