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  1. Article ; Online: Spatial and non-spatial determinants of successful tuberculosis treatment outcomes

    Goodarz Kolifarhood / Davoud Khorasani-Zavareh / Shaker Salarilak / Alireza Shoghli / Nasim Khosravi

    Journal of Epidemiology and Global Health, Vol 5, Iss

    An implication of Geographical Information Systems in health policy-making in a developing country

    2019  Volume 3

    Abstract: This retrospective study aimed to address whether or to what extent spatial and non-spatial factors with a focus on a healthcare delivery system would influence successful tuberculosis (TB) treatment outcomes in Urmia, Iran. In this cross-sectional study, ...

    Abstract This retrospective study aimed to address whether or to what extent spatial and non-spatial factors with a focus on a healthcare delivery system would influence successful tuberculosis (TB) treatment outcomes in Urmia, Iran. In this cross-sectional study, data of 452 new TB cases were extracted from Urmia TB Management Center during a 5-year period. Using the Geographical Information System (GIS), health centers and study subjects’ locations were geocoded on digital maps. To identify the statistically significant geographical clusters, Average Nearest Neighbor (ANN) index was used. Logistic regression analysis was employed to determine the association of spatial and non-spatial variables on the occurrence of adverse treatment outcomes. The spatial clusters of TB cases were concentrated in older, impoverished and outskirts areas. Although there was a tendency toward higher odds of adverse treatment outcomes among urban TB cases, this finding after adjusting for distance from a given TB healthcare center did not reach statistically significant. This article highlights effects of spatial and non-spatial determinants on the TB adverse treatment outcomes, particularly in what way the policies of healthcare services are made. Accordingly, non-spatial determinants in terms of low socio-economic factors need more attention by public health policy makers, and then more focus should be placed on the health delivery system, in particular men’s health.
    Keywords Tuberculosis ; Adverse treatment outcome ; Health policy-making ; Geographical Information System ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2019-04-01T00:00:00Z
    Publisher Springer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Access, utilization, and barriers to using malaria protection tools in migrants to Iran

    Hassan Okati-Aliabad / Alireza Ansari-Moghaddam / Mahdi Mohammadi / Jalil Nejati / Mansour Ranjbar / Ahmad Raeisi / Goodarz Kolifarhood / Fariba Shahraki-Sanavi / Alireza Khorram

    BMC Public Health, Vol 22, Iss 1, Pp 1-

    2022  Volume 9

    Abstract: Abstract Background Imported malaria cases could be considered one of the threats to malaria elimination. Therefore, increasing migrants’ access to malaria preventive measures can play an essential role in maintaining appropriate conditions and ... ...

    Abstract Abstract Background Imported malaria cases could be considered one of the threats to malaria elimination. Therefore, increasing migrants’ access to malaria preventive measures can play an essential role in maintaining appropriate conditions and preventing malaria outbreaks. This study aimed to provide detailed information about access, utilization, and barriers to using malaria protection tools in migrants to Iran. Methods This study was conducted in a vast region consisting of 4 provinces and 38 cities located in the south and southeast of the country. Study participants were migrants who moved to the study area in the past three months. A sample of 4163 migrants participated in the study. They were selected through a multi-stage sampling method to obtain a representative community sample. Data were collected through interviewer-administered questionnaires about participants’ socio-demographic specification, commuting characteristics, travel aim, access, ways of preparing, and reasons to use or not to use malaria protection tools. Quantitative and qualitative variables were described and analyzed finally. Results The mean age of individuals was 28.6 ± 10.8, with a range of 3–88 years old. Migrants’ country of origin was Afghanistan (56.6%), Pakistan (38.4%), and Iran (5%). Most migrants (69.2%) did not have malaria protection tools while staying in Iran. Among those who procured the protection tools, 74% used long-lasting insecticidal nets (LLINs), 13.4% used mosquito repellent sticks and coil, and 12.7% did not use any tools. Respectively, lack of knowledge about where they can get LLINs, followed by being expensive, unavailability in the market, not cooperation of health officer, and no need to use were expressed as the causes for having no access. The main reasons for non-using the tools were lack of knowledge about their application, followed by a defect in protection tools, ineffectiveness, and being harmful, respectively. Migrants who were supported by an employer accessed more to LLINs. Conclusions This ...
    Keywords Migrants ; Malaria ; Protection ; Iran ; Public aspects of medicine ; RA1-1270
    Subject code 306
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Epidemiological and Clinical Aspects of COVID-19; a Narrative Review

    Goodarz Kolifarhood / Mohammad Aghaali / Hossein Mozafar Saadati / Niloufar Taherpour / Sajjad Rahimi / Neda Izadi / Seyed Saeed Hashemi Nazari

    Archives of Academic Emergency Medicine, Vol 8, Iss

    2020  Volume 1

    Abstract: There are significant misconceptions and many obstacles in the way of illuminating the epidemiological and clinical aspects of COVID-19 as a new emerging epidemic. In addition, usefulness of some evidence published in the context of the recent epidemic ... ...

    Abstract There are significant misconceptions and many obstacles in the way of illuminating the epidemiological and clinical aspects of COVID-19 as a new emerging epidemic. In addition, usefulness of some evidence published in the context of the recent epidemic for decision making in clinic as well as public health is questionable. However, misinterpreting or ignoring strong evidence in clinical practice and public health probably results in less effective and somehow more harmful decisions for individuals as well as subgroups in general populations of countries in the initial stages of this epidemic. Accordingly, our narrative review appraised epidemiological and clinical aspects of the disease including genetic diversity of coronavirus genus, mode of transmission, incubation period, infectivity, pathogenicity, virulence, immunogenicity, diagnosis, surveillance, clinical case management and also successful measures for preventing its spread in some communities.
    Keywords COVID-19 ; severe acute respiratory syndrome coronavirus 2 ; epidemiology ; public health ; communicable diseases ; emerging ; Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9 ; covid19
    Subject code 610
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Shahid Beheshti University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Trends of Academic Failure and Its Demographic Determinants among Medical Students in Zanjan University of Medical Sciences

    Mehdi Eskandari / ali rostami / Azra Hojati / Goodarz Kolifarhood

    مجله ایرانی آموزش در علوم پزشکی, Vol 14, Iss 2, Pp 174-

    2014  Volume 183

    Abstract: Introduction: Study of academic failure can be helpful in identification of students at the risk of academic defeat and consequently leads to the prevention of material and human resource loss. As a result, this study was performed to determine the ... ...

    Abstract Introduction: Study of academic failure can be helpful in identification of students at the risk of academic defeat and consequently leads to the prevention of material and human resource loss. As a result, this study was performed to determine the trends of academic failure and the determinants affecting it in Zanjan University of Medical Sciences. Methods: In this descriptive cross-sectional study, all undergraduate medical students’ (n=894) data including educational and demographic characteristics were collected through Student Recording System (SAMA), for a 19 year period. Then the association between demographic attributes and academic failure determinants was tested using Binomial logistic regression analysis. Descending and ascending trends of probation and failure were determined using ARIMA statistical test. Results: In total, 28.2% of students have experienced academic failure annually. The number of students and accordingly academic failure showed a reducing trend during the years 1991-2000 but students’ admission and dropouts have had a growing trend during the following decade. The most significant explanatory variables affecting academic failure are age, gender (male), and prior qualification criteria such as quota system. Conclusion: Trends of academic failure have been affected by admission rates of medical students during the last two decades and the main determinants are educational variables and university admission criteria. Considering policies for plans to increase the number of medical students during last years, the rates of academic failure without supportive measures focused on vulnerable students, will not be avoidable.
    Keywords academic failure ; dropout ; trend ; medical student ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 302
    Language Persian
    Publishing date 2014-05-01T00:00:00Z
    Publisher Isfahan University of Medical Sciences, Medical Education Development Center
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Genome-wide association study on blood pressure traits in the Iranian population suggests ZBED9 as a new locus for hypertension

    Goodarz Kolifarhood / Siamak Sabour / Mahdi Akbarzadeh / Bahareh Sedaghati-khayat / Kamran Guity / Saeid Rasekhi Dehkordi / Mahmoud Amiri Roudbar / Farzad Hadaegh / Fereidoun Azizi / Maryam S. Daneshpour

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    2021  Volume 13

    Abstract: Abstract High blood pressure is the heritable risk factor for cardiovascular and kidney diseases. Genome-wide association studies(GWAS) on blood pressure traits increase our understanding of its underlying genetic basis. However, a large proportion of ... ...

    Abstract Abstract High blood pressure is the heritable risk factor for cardiovascular and kidney diseases. Genome-wide association studies(GWAS) on blood pressure traits increase our understanding of its underlying genetic basis. However, a large proportion of GWAS was conducted in Europeans, and some roadblocks deprive other populations to benefit from their results. Iranians population with a high degree of genomic specificity has not been represented in international databases to date, so to fill the gap, we explored the effects of 652,919 genomic variants on Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), and Hypertension (HTN) in 7694 Iranian adults aged 18 and over from Tehran Cardiometabolic Genetic Study (TCGS). We identified consistent signals on ZBED9 associated with HTN in the genome-wide borderline threshold after adjusting for different sets of environmental predictors. Moreover, strong signals on ABHD17C and suggestive signals on FBN1 were detected for DBP and SBP, respectively, while these signals were not consistent in different GWA analysis. Our finding on ZBED9 was confirmed for all BP traits by linkage analysis in an independent sample. We found significant associations with similar direction of effects and allele frequency of genetic variants on ZBED9 with DBP (genome-wide threshold) and HTN (nominal threshold) in GWAS summary data of UK Biobank. Although there is no strong evidence to support the function of ZBED9 in blood pressure regulation, it provides new insight into the pleiotropic effects of hypertension and other cardiovascular diseases.
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Hepatitis B surface antigen prevalence in pregnant women

    Alireza Shoghli / Seyed Mahmood Nabavi / Seyed Moayed Alavian / Goodarz Kolifarhood / Mohammad Mehdi Goya / Roshanak Namazi / Mojtaba Fallahnezhad / Mansor Mohajeri / Nouraldin Mousavinasab / Rahim Sorouri Zanjani / Mohammad Reza Saeini / Ahmad Jalilvand

    International Journal of Preventive Medicine, Vol 5, Iss 15, Pp 213-

    A cross-sectional survey in Iran

    2014  Volume 218

    Abstract: Background: Vertical transmission of hepatitis B virus (HBV) from infected mothers to their neonates is one of the most important routes of infection. The exact prevalence rate of HBV in Iranian pregnant mothers is not well known but based on different ... ...

    Abstract Background: Vertical transmission of hepatitis B virus (HBV) from infected mothers to their neonates is one of the most important routes of infection. The exact prevalence rate of HBV in Iranian pregnant mothers is not well known but based on different studies it is estimated between 0.35% and 6.5%. The aim of this study was to determine the seroprevalence of hepatitis B surface antigen (HBsAg) in pregnant women of selected provinces in Iran. Methods: At this cross-sectional study, seven provinces supposed to be of high and low prevalence of hepatitis B in the general population selected. Multistage sampling was used to enroll 5261 parturient women who attended the target provinces birth facilities, during January to March of 2011, were recruited to study. To determine the statistically significant mean and proportion differences, t-test and c2 test were used, respectively. Results: Overall 1.2% was positive HBsAg of which 11% of them were hepatitis B e-antigen positive as well. The eastern and north eastern provinces were considerably higher in HBsAg seropositivity than the west and northwest of the country. Conclusions: In view of the considerable prevalence of hepatitis B in pregnant women, screening all pregnant women prioritizing the eastern and north-eastern provinces is strongly recommended.
    Keywords Hepatitis B ; Iran ; pregnant women ; prevalence ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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