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Article ; Online: Prenatal diagnosis of meningomyelocele resolves as a mature cystic teratoma in the thoracolumbar region.

Chen-Carrington, Annie / Leonard, Dean / Goodreau, Adam / Rhodes, Jennifer / Tye, Gary W

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

2024

Abstract: A mature cystic teratoma is a mass with heterogeneous appearance, consisting of adult tissue with two or three layers: endoderm, mesoderm, and ectoderm. It is a rare, benign transformation of somatic tissue most commonly found in the sacrococcygeal ... ...

Abstract	A mature cystic teratoma is a mass with heterogeneous appearance, consisting of adult tissue with two or three layers: endoderm, mesoderm, and ectoderm. It is a rare, benign transformation of somatic tissue most commonly found in the sacrococcygeal region and may resemble an uncomplicated spina bifida on prenatal ultrasonography. In this case report, we describe a female newborn with an extremely rare mature cystic teratoma in the thoracolumbar region. She presented prenatally with a preliminary diagnosis of meningomyelocele, diastematomyelia, and Chiari II malformation and a possible teratoma. However, a mass containing solid glandular tissues and bony calcifications approximately 3 × 4 cm in size was observed in the thoracolumbar region upon birth. During surgical resection, no nerve roots were found in the associated meningocele. The patient retained full lower body function postoperatively following surgical excision of the thecal sac and teratoma.
Language	English
Publishing date	2024-04-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	605988-0
ISSN	1433-0350 ; 0302-2803 ; 0256-7040
ISSN (online)	1433-0350
ISSN	0302-2803 ; 0256-7040
DOI	10.1007/s00381-024-06396-7
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Article ; Online: Omega Lift after Total Capsulectomy in Prior Breast Augmentation.

Miller, Jonathan E / Goodreau, Adam M / Blanchet, Nadia P

Plastic and reconstructive surgery

2020 Volume 146, Issue 6, Page(s) 835e–836e

MeSH term(s)	Breast Implantation/adverse effects ; Device Removal/adverse effects ; Device Removal/methods ; Female ; Humans ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Treatment Outcome
Language	English
Publishing date	2020-11-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000007383
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Article: Assessing Use of Gender Diverse Language in Patient Education Materials on Breast Reconstruction.

Powell, Lauren E / Smith, Rachel M / Baek, Annabel E / Goodreau, Adam M / Pozez, Andrea L

Plastic and reconstructive surgery. Global open

2022 Volume 10, Issue 6, Page(s) e4400

Abstract: Utilizing inclusive terminology in patient education materials is an increasing area of focus in plastic surgery. Over 300,000 cases of breast cancer were diagnosed in 2020, affecting cisgender and gender diverse patients alike. Both cisgender and gender ...

Abstract	Utilizing inclusive terminology in patient education materials is an increasing area of focus in plastic surgery. Over 300,000 cases of breast cancer were diagnosed in 2020, affecting cisgender and gender diverse patients alike. Both cisgender and gender diverse patients may choose to undergo breast reconstruction. This study aims to assess the use of inclusive language in online patient education materials on reconstruction after breast cancer. Methods: Materials were collected from all academic hospitals with a plastic surgery integrated and/or independent residency program, 97 in total. Programs were further classified by the presence of a comprehensive gender program. Materials were analyzed for gender diverse terminology outlined by the National LGBTQIA+ Health Education Center. A chi-square test evaluated for statistical significance of inclusive terminology based on the presence or absence of a comprehensive gender program. Results: The majority (75%) of programs referenced cis women alone, with 25% referring to both men and women or using gender neutral terms such as "patients." Although most (85%) programs wrote in second person ("you"), 15% used she/her/hers pronouns alone, and no programs utilized gender diverse language outlined by the National LGBTQIA+ Health Education Center. The presence or absence of a comprehensive gender program was not predictive of the use of inclusive terminology ( Conclusions: This study found that only 25% of breast reconstruction materials contained inclusive gender terminology. Plastic surgeons should provide patient education materials with language that supports members of a gender diverse population to facilitate a safe, inclusive space and conversation.
Language	English
Publishing date	2022-06-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2851682-5
ISSN	2169-7574 ; 2169-7574
ISSN (online)	2169-7574
ISSN	2169-7574
DOI	10.1097/GOX.0000000000004400
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Article ; Online: Revising Prepectoral Breast Reconstruction.

Goodreau, Adam M / Driscoll, Cassandra R / Nye, Anthony / Nigro, Lauren C / Blanchet, Nadia P

Plastic and reconstructive surgery

2022 Volume 149, Issue 3, Page(s) 579–584

Abstract: Summary: Prepectoral prosthetic breast reconstruction continues to gain popularity, largely due to its decreased postoperative pain, animation deformity, and operative time as compared to subpectoral reconstruction. Widespread use has led to ... ...

Abstract	Summary: Prepectoral prosthetic breast reconstruction continues to gain popularity, largely due to its decreased postoperative pain, animation deformity, and operative time as compared to subpectoral reconstruction. Widespread use has led to opportunities for surgical revisions. While some techniques for submuscular reconstruction revisions, such as implant exchange and fat grafting, also apply to prepectoral revisions, others require modification for the prepectoral space. The prosthesis' unique reliance on the mastectomy flaps and acellular dermal matrix for support leads to a progressive alteration of the breast footprint, conus, envelope, and nipple-areola complex position. To date, revisions of prepectoral reconstructions have not been addressed in the literature. This article presents the senior author's (N.P.B.) techniques for (1) revising prepectoral breast reconstructions, including staged and direct-to-implant reconstructions, with a special focus on nipple-sparing reconstruction, and (2) minimizing undesirable outcomes of prepectoral reconstruction.
MeSH term(s)	Acellular Dermis ; Adult ; Aged ; Breast Implantation/methods ; Female ; Humans ; Mammaplasty/methods ; Mastectomy/methods ; Middle Aged ; Pectoralis Muscles/surgery ; Reoperation/methods ; Retrospective Studies ; Young Adult
Language	English
Publishing date	2022-02-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000008850
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Article ; Online: Invasive stage III breast implant-associated anaplastic large cell lymphoma successfully treated with incomplete resection.

Nestler, John A / Kim, Jin Kyung / Goodreau, Adam M / Mountziaris, Paschalia M / McGuire, Kandace P

BMJ case reports

2022 Volume 15, Issue 4

Abstract: A woman with history of bilateral breast augmentation 15 years prior presented with right breast swelling, peri-implant effusion and a palpable inferomedial mass. Effusion aspiration demonstrated pleiomorphic cells consistent with breast implant- ... ...

Abstract	A woman with history of bilateral breast augmentation 15 years prior presented with right breast swelling, peri-implant effusion and a palpable inferomedial mass. Effusion aspiration demonstrated pleiomorphic cells consistent with breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). Further diagnostic studies confirmed stage III disease with a 4.7 cm right breast mass and fluorodeoxyglucose uptake in an internal mammary chain lymph node. The patient underwent surgery with incomplete resection due to invasion of the chest wall followed by chemotherapy and radiation therapy. BIA-ALCL typically presents as an indolent effusion, however advanced disease carries a worse prognosis. This case highlights successful treatment without recurrence past the one-year mark as well as the need for multidisciplinary management when dealing with advanced disease.
MeSH term(s)	Breast/pathology ; Breast Implantation/adverse effects ; Breast Implants/adverse effects ; Female ; Humans ; Lymphoma, Large-Cell, Anaplastic/diagnostic imaging ; Lymphoma, Large-Cell, Anaplastic/etiology ; Lymphoma, Large-Cell, Anaplastic/therapy ; Mammaplasty
Language	English
Publishing date	2022-04-04
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2021-246664
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Article: Accurate Nipple Areolar Positioning in Nipple-sparing Mastectomy Reconstruction.

Mayer, Alexander P / Goodreau, Adam M / Blanchet, Nadia P

Plastic and reconstructive surgery. Global open

2019 Volume 7, Issue 1, Page(s) e2064

Abstract: Nipple-sparing mastectomy continues to grow in popularity as oncologic indications for preserving the nipple areolar complex have become less stringent and more patients with genetic predispositions to breast cancer seek aesthetically superior ... ...

Abstract	Nipple-sparing mastectomy continues to grow in popularity as oncologic indications for preserving the nipple areolar complex have become less stringent and more patients with genetic predispositions to breast cancer seek aesthetically superior prophylactic mastectomy reconstructions. Nonetheless, nipple malposition remains a common and disturbing complication. This article proposes several anatomic variations that predispose to nipple malposition and a strategy to avoid it through a reliable, easily reproducible method of preoperative marking and intraoperative stabilization.
Language	English
Publishing date	2019-01-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2851682-5
ISSN	2169-7574 ; 2169-7574
ISSN (online)	2169-7574
ISSN	2169-7574
DOI	10.1097/GOX.0000000000002064
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Article ; Online: Impact of renal function recovery utilizing left ventricular assist device support.

Quader, Mohammed / Goodreau, Adam M / Johnson, Ryan M / Wolfe, Luke G / Feldman, George M

Journal of cardiac surgery

2019 Volume 35, Issue 1, Page(s) 100–107

Abstract: Background: In heart failure (HF) patients with renal insufficiency (RI), we hypothesize that mechanical circulatory support (MCS) with the left ventricular assist device (LVAD) will promote renal function recovery (RR). We sought to quantify RR with ... ...

Abstract	Background: In heart failure (HF) patients with renal insufficiency (RI), we hypothesize that mechanical circulatory support (MCS) with the left ventricular assist device (LVAD) will promote renal function recovery (RR). We sought to quantify RR with LVAD support over 6 months of follow-up. Methods: RR data at 30, 90, and 180 days were analyzed for all LVAD patients with RI at the time of surgery. RI was defined as either the use of hemodialysis (HD) or a glomerular filtration rate (GFR) less than 60 mL/min/1.73 m Results: Between January 2008 and December 2013, 47 of 127 (37%) LVAD recipients had RI at the time of surgery. The mean preoperative GFR was 48 ± 7. We observed RR at each follow-up, with 30-, 90-, and 180-day mean GFRs of 79 ± 33, 71 ± 31, and 63 ± 21, respectively. The absolute increase in GFR at 30, 90, and 180 days was 34 ± 31, 26 ± 29, and 19 ± 20, respectively (All with P < .001). Four patients (8.5%) with RI required HD preoperatively. Of these, three recovered renal function, the fourth patient died. An additional 13 patients (30.2%) that were previously non-HD-dependent required HD postoperatively. Six of these 13 (46%) recovered renal function during the study period, four (30.7%) remain on HD and three (23%) died. Conclusions: RI improves significantly with LVAD support. Improvements in GFR are marked in the first 30 days. Among those patients requiring either pre- or post-operative HD, a majority recovered renal function.
MeSH term(s)	Adult ; Aged ; Female ; Follow-Up Studies ; Heart Failure/therapy ; Heart Ventricles ; Heart-Assist Devices ; Humans ; Kidney/physiology ; Male ; Middle Aged ; Recovery of Function ; Time Factors ; Treatment Outcome
Language	English
Publishing date	2019-11-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	639059-6
ISSN	1540-8191 ; 0886-0440
ISSN (online)	1540-8191
ISSN	0886-0440
DOI	10.1111/jocs.14320
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Article ; Online: Spotlight in Plastic Surgery: January 2021.

Phillips, Brett T / Abtahi, Ali R / Azoury, Saïd C / Brito, Íris M / Cohen, Joshua M / Goodreau, Adam M / Kamel, George N / Keyes, Michael S / Safran, Tyler / Gosain, Arun K

Plastic and reconstructive surgery

2020 Volume 147, Issue 1, Page(s) 264–266

Language	English
Publishing date	2020-12-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000007538
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Article ; Online: Outward Currents Contributing to Inspiratory Burst Termination in preBötzinger Complex Neurons of Neonatal Mice Studied in Vitro.

Krey, Rebecca A / Goodreau, Adam M / Arnold, Thomas B / Del Negro, Christopher A

Frontiers in neural circuits

2010 Volume 4, Page(s) 124

Abstract: We studied preBötzinger Complex (preBötC) inspiratory interneurons to determine the cellular mechanisms that influence burst termination in a mammalian central pattern generator. Neonatal mouse slice preparations that retain preBötC neurons generate ... ...

Abstract	We studied preBötzinger Complex (preBötC) inspiratory interneurons to determine the cellular mechanisms that influence burst termination in a mammalian central pattern generator. Neonatal mouse slice preparations that retain preBötC neurons generate respiratory motor rhythms in vitro. Inspiratory-related bursts rely on inward currents that flux Na(+), thus outward currents coupled to Na(+) accumulation are logical candidates for assisting in, or causing, burst termination. We examined Na(+)/K(+) ATPase electrogenic pump current (I(pump)), Na(+)-dependent K(+) current (I(K-Na)), and ATP-dependent K(+) current (I(K-ATP)). The pharmacological blockade of I(pump), I(K-Na), or I(K-ATP) caused pathological depolarization akin to a burst that cannot terminate, which impeded respiratory rhythm generation and reversibly stopped motor output. By simulating inspiratory bursts with current-step commands in synaptically isolated preBötC neurons, we determined that each current generates approximately 3-8 mV of transient post-burst hyperpolarization that decays in 50-1600 ms. I(pump), I(K-Na), and - to a lesser extent - I(K-ATP) contribute to terminating inspiratory bursts in the context of respiratory rhythm generation by responding to activity dependent cues such as Na(+) accumulation.
Language	English
Publishing date	2010-11-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2452968-0
ISSN	1662-5110 ; 1662-5110
ISSN (online)	1662-5110
ISSN	1662-5110
DOI	10.3389/fncir.2010.00124
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Article ; Online: Renal Function Recovery with Total Artificial Heart Support.

Quader, Mohammed A / Goodreau, Adam M / Shah, Keyur B / Katlaps, Gundars / Cooke, Richard / Smallfield, Melissa C / Tchoukina, Inna F / Wolfe, Luke G / Kasirajan, Vigneshwar

ASAIO journal (American Society for Artificial Internal Organs : 1992)

2016 Volume 62, Issue 1, Page(s) 87–91

Abstract: Heart failure patients requiring total artificial heart (TAH) support often have concomitant renal insufficiency (RI). We sought to quantify renal function recovery in patients supported with TAH at our institution. Renal function data at 30, 90, and 180 ...

Abstract	Heart failure patients requiring total artificial heart (TAH) support often have concomitant renal insufficiency (RI). We sought to quantify renal function recovery in patients supported with TAH at our institution. Renal function data at 30, 90, and 180 days after TAH implantation were analyzed for patients with RI, defined as hemodialysis supported or an estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73 m. Between January 2008 and December 2013, 20 of the 46 (43.5%) TAH recipients (age 51 ± 9 years, 85% men) had RI, mean preoperative eGFR of 48 ± 7 ml/min/1.73 m. Renal function recovery was noted at each follow-up interval: increment in eGFR (ml/min/1.73 m) at 30, 90, and 180 days was 21 ± 35 (p = 0.1), 16.5 ± 18 (p = 0.05), and 10 ± 9 (p = 0.1), respectively. Six patients (30%) required preoperative dialysis. Of these, four recovered renal function, one remained on dialysis, and one died. Six patients (30%) required new-onset dialysis. Of these, three recovered renal function and three died. Overall, 75% (15 of 20) of patients' renal function improved with TAH support. Total artificial heart support improved renal function in 75% of patients with pre-existing significant RI, including those who required preoperative dialysis.
MeSH term(s)	Adult ; Female ; Heart Failure/complications ; Heart Failure/surgery ; Heart, Artificial ; Humans ; Male ; Middle Aged ; Recovery of Function ; Renal Insufficiency/etiology ; Renal Insufficiency/surgery
Language	English
Publishing date	2016-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	759982-1
ISSN	1538-943X ; 0162-1432 ; 1058-2916
ISSN (online)	1538-943X
ISSN	0162-1432 ; 1058-2916
DOI	10.1097/MAT.0000000000000288
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