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Article: Body dissatisfaction and low self-esteem in elementary school-aged children: the role of media pressure and trust in parent-child relationships.

De Coen, Jolien / Verbeken, Sandra / Goossens, Lien

2024 Volume 14, Page(s) 1228860

Abstract: Studies have indicated that the media plays a role in the development of body dissatisfaction in children. Nevertheless, there is limited understanding of the protective factors that may reduce this association, such as the parent-child relationship. ... ...

Abstract	Studies have indicated that the media plays a role in the development of body dissatisfaction in children. Nevertheless, there is limited understanding of the protective factors that may reduce this association, such as the parent-child relationship. Therefore, this study investigates children's body dissatisfaction and self-esteem and the role of media pressure and a trust in parent-child relationships herein. A sample of
Language	English
Publishing date	2024-01-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2023.1228860
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Article ; Online: Depression in middle childhood: secure base script as a cognitive diathesis in the relationship between daily stress and depressive symptoms.

van Aswegen, T / Seedat, S / van Straten, A / Goossens, L / Bosmans, G

Attachment & human development

2023 Volume 25, Issue 3-4, Page(s) 353–367

Abstract: A better understanding of protective factors against childhood depression may allow for the mitigation of severe and chronic symptoms and the timely implementation of intervention strategies. This study investigated the protective effect of having a ... ...

Abstract	A better understanding of protective factors against childhood depression may allow for the mitigation of severe and chronic symptoms and the timely implementation of intervention strategies. This study investigated the protective effect of having a secure base script on depressive symptoms when children face daily stressors. To test this hypothesis, moderation analyses were performed in a cross-sectional study with 378 children (48.5% boys, 51.5%) aged 8-12 years (
MeSH term(s)	Male ; Humans ; Child ; Female ; Depression/epidemiology ; Cross-Sectional Studies ; Disease Susceptibility ; Object Attachment ; Cognition
Language	English
Publishing date	2023-04-20
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1497969-x
ISSN	1469-2988 ; 1461-6734
ISSN (online)	1469-2988
ISSN	1461-6734
DOI	10.1080/14616734.2023.2204837
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Zs.A 5448: Show issues

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Article ; Online: Cause of death and making end-of-life decisions in preterm infants has not changed over time: A mortality follow-back survey.

Goossens, Linde / Dombrecht, Laure / Chambaere, Kenneth / Beernaert, Kim / Cools, Filip

Acta paediatrica (Oslo, Norway : 1992)

2024

Abstract: Aim: This study aimed to evaluate changes over time in cause of death and making end-of-life decisions in preterm infants.: Methods: A follow-back survey was conducted of all preterm infants who died between September 2016 and December 2017 in ... ...

Abstract	Aim: This study aimed to evaluate changes over time in cause of death and making end-of-life decisions in preterm infants. Methods: A follow-back survey was conducted of all preterm infants who died between September 2016 and December 2017 in Flanders and Brussels, Belgium. Cause of death was obtained from the death certificate and information on end-of-life decisions (ELDs) through an anonymous questionnaire of the certifying physician. Results were compared with a previous study performed between August 1999 and July 2000. Results: In the cohort 1999-2000 and 2016-2017, respectively, 150 and 135 deaths were included. A significantly higher proportion of infants born before 26 weeks of gestation was found in the 2016-2017 cohort (53% vs. 24% in 1999-2000, p < 0.001). Extreme immaturity (<26 weeks) remained the most prevalent cause with a significant increase in the 2016-2017 cohort (48% vs. 28% in 1999-2000, p < 0.001). The overall prevalence of ELDs was similar across study periods (61%). Non-treatment decisions remained the most common ELD (36% and 37%). Conclusion: Infants born at the limits of viability have become more prevalent among infant deaths, possibly due to a change in attitude towards periviable births. Neither the process of making ELDs nor the cause of death has changed over time.
Language	English
Publishing date	2024-02-12
Publishing country	Norway
Document type	Journal Article
ZDB-ID	203487-6
ISSN	1651-2227 ; 0365-1436 ; 0803-5253
ISSN (online)	1651-2227
ISSN	0365-1436 ; 0803-5253
DOI	10.1111/apa.17153
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Article ; Online: Individualized, connectome-based, non-invasive stimulation of OCD deep-brain targets: A proof-of-concept.

Baldi, Samantha / Schuhmann, Teresa / Goossens, Liesbet / Schruers, Koen R J

NeuroImage

2024 Volume 288, Page(s) 120527

Abstract: Treatment-resistant obsessive-compulsive disorder (OCD) generally improves with deep-brain stimulation (DBS), thought to modulate neural activity at both the implantation site and in connected brain regions. However, its invasive nature, side-effects, ... ...

Abstract	Treatment-resistant obsessive-compulsive disorder (OCD) generally improves with deep-brain stimulation (DBS), thought to modulate neural activity at both the implantation site and in connected brain regions. However, its invasive nature, side-effects, and lack of customization, make non-invasive treatments preferable. Harnessing the established remote effects of cortical transcranial magnetic stimulation (TMS), connectivity-based approaches have emerged for depression that aim at influencing distant regions connected to the stimulation site. We here investigated whether effective OCD DBS targets (here subthalamic nucleus [STN] and nucleus accumbens [NAc]) could be modulated non-invasively with TMS. In a proof-of-concept study with nine healthy individuals, we used 7T magnetic resonance imaging (MRI) and probabilistic tractography to reconstruct the fiber tracts traversing manually segmented STN/NAc. Two TMS targets were individually selected based on the strength of their structural connectivity to either the STN, or both the STN and NAc. In a sham-controlled, within-subject cross-over design, TMS was administered over the personalized targets, located around the precentral and middle frontal gyrus. Resting-state functional 3T MRI was acquired before, and at 5 and 25 min after stimulation to investigate TMS-induced changes in the functional connectivity of the STN and NAc with other regions of the brain. Static and dynamic seed-to-voxel correlation analyses were conducted. TMS over both targets was able to modulate the functional connectivity of the STN and NAc, engaging both overlapping and distinct regions, and unfolding following different temporal dynamics. Given the relevance of the engaged connected regions to OCD pathology, we argue that a personalized, connectivity-based procedure is worth investigating as potential treatment for refractory OCD.
MeSH term(s)	Humans ; Deep Brain Stimulation/methods ; Connectome ; Brain/diagnostic imaging ; Transcranial Magnetic Stimulation ; Magnetic Resonance Imaging ; Obsessive-Compulsive Disorder/diagnostic imaging ; Obsessive-Compulsive Disorder/therapy
Language	English
Publishing date	2024-01-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	1147767-2
ISSN	1095-9572 ; 1053-8119
ISSN (online)	1095-9572
ISSN	1053-8119
DOI	10.1016/j.neuroimage.2024.120527
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Zs.A 3664: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Examining the whole plate: The role of the family context in the understanding of children's food refusal behaviors.

Taquet, Juliette / Verbeken, Sandra / Goossens, Lien

Eating behaviors

2023 Volume 52, Page(s) 101828

Abstract: Introduction: In the context of understanding children's food refusal behaviors, such as food fussiness and food neophobia, research has predominantly focused on the role of parental feeding strategies. However, little is known about which general ... ...

Abstract	Introduction: In the context of understanding children's food refusal behaviors, such as food fussiness and food neophobia, research has predominantly focused on the role of parental feeding strategies. However, little is known about which general family context variables add to the understanding of children's food refusal behaviors. The purpose of this study was to examine the relation between 1) parents' own use of maladaptive emotion regulation strategies when they are anxious, 2) parents' reactions towards their children's emotions in stressful situations, and 3) parenting styles on the one hand, and children's food refusal behaviors on the other. Methods: Mothers and fathers (N = 157) of young children (M = 4.64, SD = 1.7) completed a series of self- and parent-report questionnaires. Results: The model examining the role of parenting styles was found to be significantly related to food refusal behaviors in children. More specifically, the current findings demonstrate that higher levels of a coercive parenting style were associated with higher levels of both food fussiness and food neophobia in children. Furthermore, higher levels of a chaotic parenting styles were associated with higher levels of food neophobia in children. The models examining parents' maladjusted emotion regulation strategies when anxious and parents' reactions towards their children's emotions during stressful situations were not found to be significant. Conclusions: Factors related to the parenting style appear to be important for understanding food refusal behaviors in children. Replication of the findings using longitudinal and observational designs is needed.
MeSH term(s)	Child ; Female ; Humans ; Child, Preschool ; Parents/psychology ; Emotions ; Mothers/psychology ; Anxiety ; Parenting/psychology ; Feeding Behavior/psychology ; Surveys and Questionnaires ; Parent-Child Relations ; Child Behavior
Language	English
Publishing date	2023-11-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2073366-5
ISSN	1873-7358 ; 1471-0153
ISSN (online)	1873-7358
ISSN	1471-0153
DOI	10.1016/j.eatbeh.2023.101828
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Zs.A 6208: Show issues

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Book ; Conference proceedings: Expert judgement and accident consequence uncertainty analysis

Goossens, L. H. J.

based upon papers presented at two Workshops "Methods for Expert Judgement and Uncertainty Analysis" and "Uncertainty Analysis of Accident Consequence Predictions of COSYMA and its Sub-Modules" held at Avifauna, Alphen a/d Rijn, The Netherlands, June 21 - 24 1999

(Radiation protection dosimetry ; 90,3 = Special Issue)

2000

Institution	Workshop on Methods for Expert Judgement and Uncertainty Analysis Workshop on Uncertainty Analysis of Accident Consequence Predictions of COSYMA and its Sub-Modules
Author's details	ed. L. H. J. Goossens
Series title	Radiation protection dosimetry ; 90,3 = Special Issue
Collection
Language	English
Size	S. 290 - 384 : graph. Darst.
Publisher	Nuclear Technology Publ
Publishing place	Ashford, Kent
Publishing country	Great Britain
Document type	Book ; Conference proceedings
HBZ-ID	HT012826021
ISBN	1-870965-64-7 ; 978-1-870965-64-4
Database	Catalogue ZB MED Medicine, Health

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Article ; Online: Assessment of the Adherence to ESPGHAN 2018 Guidelines in the Neonatal Intensive Care Unit of the Ghent University Hospital: A Retrospective Study.

De Cloet, Joeri / Simal, Ine / Benoot, Karel / Goossens, Linde

Nutrients

2023 Volume 15, Issue 10

Abstract: Parenteral nutrition (PN) is a standard of care for preterm infants in the first postnatal days. The European Society of Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) has updated their guideline recommendations on PN in 2018. However, ... ...

Abstract	Parenteral nutrition (PN) is a standard of care for preterm infants in the first postnatal days. The European Society of Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) has updated their guideline recommendations on PN in 2018. However, data on actual 2018 guideline adherence in clinical practice are sparse. In this retrospective study, conducted at the neonatal intensive care unit (NICU) of Ghent University Hospital, we analyzed the ESPGHAN 2018 PN guideline adherence and growth for 86 neonates admitted to the NICU. Analyses were stratified by birth weight (<1000 g, 1000 to <1500 g, ≥1500 g). We documented the provisions for enteral nutrition (EN) and PN, and we tested the combined EN and PN provisions for ESPGHAN 2018 adherence. The nutrition protocols showed a high adherence to PN guidelines in terms of carbohydrate provisions, yet lipid provisions for EN and PN often exceeded the recommended maximum of 4 g/kg/d; although, PN lipid intakes maxed out at 3.6 g/kg/d. Protein provisions tended to fall below the recommended minimum of 2.5 g/kg/d for preterm infants and 1.5 g/kg/d for term neonates. The energy provisions also tended to fall below the minimum recommendations, especially for neonates with a birth weight (BW) < 1000 g. Over a mean PN duration of 17.1 ± 11.4 d, the median weekly Fenton Z-scores changes for length, weight, and head circumference were positive for all BW groups. Future studies have to assess how protocols adapt to current guidelines, and how this affects short- and long-term growth across different BW groups. In conclusion, the reported findings provide real-world evidence regarding the effect of ESPGHAN 2018 PN guideline adherence, and they demonstrate how standardized neonatal PN solutions can safeguard stable growth during NICU stays.
MeSH term(s)	Infant ; Child ; Humans ; Infant, Newborn ; Infant, Premature ; Birth Weight ; Retrospective Studies ; Intensive Care Units, Neonatal ; Gastroenterology ; Hospitals ; Lipids
Chemical Substances	Lipids
Language	English
Publishing date	2023-05-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15102324
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Article ; Online: Soluble TIM-3 as a biomarker of progression and therapeutic response in cancers and other of human diseases.

Bailly, Christian / Thuru, Xavier / Goossens, Laurence / Goossens, Jean-François

Biochemical pharmacology

2023 Volume 209, Page(s) 115445

Abstract: Immune checkpoints inhibition is a privileged approach to combat cancers and other human diseases. The TIM-3 (T cell immunoglobulin and mucin-domain containing-3) inhibitory checkpoint expressed on different types of immune cells is actively investigated ...

Abstract	Immune checkpoints inhibition is a privileged approach to combat cancers and other human diseases. The TIM-3 (T cell immunoglobulin and mucin-domain containing-3) inhibitory checkpoint expressed on different types of immune cells is actively investigated as an anticancer target, with a dozen of monoclonal antibodies in (pre)clinical development. A soluble form sTIM-3 can be found in the plasma of patients with cancer and other diseases. This active circulating protein originates from the proteolytic cleavage by two ADAM metalloproteases of the membrane receptor shared by tumor and non-tumor cells, and extracellular vesicles. In most cancers but not all, overexpression of mTIM-3 at the cell surface leads to high level of sTIM-3. Similarly, elevated levels of sTIM-3 have been reported in chronic autoimmune diseases, inflammatory gastro-intestinal diseases, certain viral and parasitic diseases, but also in cases of organ transplantation and in pregnancy-related pathologies. We have analyzed the origin of sTIM-3, its methods of dosage in blood or plasma, its presence in multiple diseases and its potential role as a biomarker to follow disease progression and/or the treatment response. In contrast to sPD-L1 generated by different classes of proteases and by alternative splicing, sTIM-3 is uniquely produced upon ADAM-dependent shedding, providing a more homogenous molecular entity and a possibly more reliable molecular marker. However, the biological functionality of sTIM-3 remains insufficiently characterized. The review shed light on pathologies associated with an altered expression of sTIM-3 in human plasma and the possibility to use sTIM-3 as a diagnostic or therapeutic marker.
MeSH term(s)	Humans ; Biomarkers/metabolism ; Cell Membrane/metabolism ; Hepatitis A Virus Cellular Receptor 2/metabolism ; Neoplasms/metabolism
Chemical Substances	Biomarkers ; Hepatitis A Virus Cellular Receptor 2 ; HAVCR2 protein, human
Language	English
Publishing date	2023-02-02
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	208787-x
ISSN	1873-2968 ; 0006-2952
ISSN (online)	1873-2968
ISSN	0006-2952
DOI	10.1016/j.bcp.2023.115445
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Zs.A 19: Show issues

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Article ; Online: Subtyping youngsters with obesity: A theory-based cluster analysis.

Vervoort, L / Naets, T / Goossens, L / Verbeken, S / Claes, L / Tanghe, A / Braet, C

Appetite

2021 Volume 168, Page(s) 105723

Abstract: Psychological mechanisms play a crucial role in explaining weight gain. Aim of the present study was to identify subtypes in youngsters with obesity in line with these mechanisms. Defining homogeneous clusters within this heterogeneous group provides ... ...

Abstract	Psychological mechanisms play a crucial role in explaining weight gain. Aim of the present study was to identify subtypes in youngsters with obesity in line with these mechanisms. Defining homogeneous clusters within this heterogeneous group provides relevant information for personalized treatments. Data were collected in N = 572 participants (51% boys, aged 7-19) with extreme obesity (%BMI M = 187.8; SD = 30.9) recruited in an inpatient treatment centre. Based on psychological models of overweight/obesity, the Affect Regulation Model, the Reward Deficiency Model and The Dual Pathway Model, cluster variables were selected assessing emotional eating, reward reactivity and regulative capacities. Youngsters reported on emotional eating (DEBQ Emotional Eating) and reward sensitivity (BAS), while parents reported on children's regulative Executive Functions (BRIEF). Characteristics of the different clusters were examined concerning weight variables (pre and post treatment) and variables indexing problematic eating (DEBQ External Eating, Ch-EDE), affect regulation (FEEL-KJ) and depressive symptoms (CDI). Hierarchical cluster analyses supported the presence of three clusters, further evaluated by K-means cluster analyses. The cluster solutions differed according to age and sex (boys 7-13, boys 14-19, girls 7-13, girls 14-19). In all four age and gender subsamples, an "Emotional Eating" cluster displaying a vulnerable profile (high depression, maladaptive emotion regulation, problematic eating) and a "Reward Deficiency" cluster displaying a more resilient profile were detected. In girls 7-13, a "Weak Executive Functioning" indicative of insufficient self-regulative capacities, showed moderate to high emotional problems and problematic eating. In the other subgroups, the "Mean Level Functioning" cluster also showed elevated emotional problems and problematic eating. Given that different clusters can be identified, and given that these clusters have different profiles on emotional problems and problematic eating, subtyping youngsters with severe obesity is indicated, setting the stage for personalized treatments.
MeSH term(s)	Body Mass Index ; Cluster Analysis ; Feeding Behavior ; Female ; Humans ; Male ; Obesity ; Overweight ; Surveys and Questionnaires
Language	English
Publishing date	2021-10-01
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1461347-5
ISSN	1095-8304 ; 0195-6663
ISSN (online)	1095-8304
ISSN	0195-6663
DOI	10.1016/j.appet.2021.105723
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Article: Jugend und Sport

Goossens, Lode

Sportphysio

2017 Volume 05, Issue 04, Page(s) 186–190

Abstract: VERLETZUNGSPRÄVENTION: Junge Menschen im Sport fördern, Überlastungen vermeiden und so die Freude an der Bewegung bis ins hohe Alter behalten – das ist ein Ziel, das sowohl Eltern als auch Trainer und Sportvereine ...

Abstract	VERLETZUNGSPRÄVENTION: Junge Menschen im Sport fördern, Überlastungen vermeiden und so die Freude an der Bewegung bis ins hohe Alter behalten – das ist ein Ziel, das sowohl Eltern als auch Trainer und Sportvereine verbindet. Gerade verletzte Jugendliche neigen jedoch dazu, den Sport aus ihrem Leben zu streichen. Ein verantwortungsvoller Umgang unterstützt junge Talente in ihrer sportlichen Entwicklung und kann so dieses Dilemma verhindern.
Language	German
Publishing date	2017-11-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article
ISSN	2196-596X ; 2196-5951
ISSN (online)	2196-596X
ISSN	2196-5951
DOI	10.1055/s-0043-119025
Database	Thieme publisher's database

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