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Article ; Online: Gallstone ileus of the sigmoid colon

Goran Augustin / Paula Batur / Tomislav Bruketa

Liječnički vjesnik, Vol 143, Iss 5-6, Pp 181-

a case report

2021 Volume 183

Abstract: Gallstone ileus is a rare form of mechanical bowel obstruction with a biliary calculus due to complicated biliary lithiasis. The most common obstructed segment is small bowel. Colonic gallstone ileus is much rarer. Older patients with comorbidities are ... ...

Abstract	Gallstone ileus is a rare form of mechanical bowel obstruction with a biliary calculus due to complicated biliary lithiasis. The most common obstructed segment is small bowel. Colonic gallstone ileus is much rarer. Older patients with comorbidities are affected more frequently, and also women more often than men. Older age and comorbidities increase the mortality rate, additionally if the diagnosis and treatment are delayed. Since gallstone ileus is curable, it is necessary to confirm it with an abdominal CT scan or plain abdominal X-ray. Therapeutic procedures include laparotomy or laparoscopy with cololithotomy and endoscopic lithotripsy. We present a case of a 63-year-old woman who came to the emergency department with colicky abdominal pain and elevated serum inflammatory markers. Obstruction of the sigmoid colon with 4.8 cm calculus is detected with the abdominal CT scan, and it was successfully treated with laparotomy and cololithotomy.
Keywords	gallstones – complications ; diagnostic imaging ; surgery ; ileus – diagnostic imaging ; etiology ; intestinal obstruction – diagnostic imaging ; sigmoid diseases – diagnostic imaging ; laparotomy ; tomography ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	Hrvatski liječnički zbor
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Giant, rapid-growing lipoma of Retzius space

Goran Augustin / Lucija Brkić / Zlatko Marušić

Liječnički vjesnik, Vol 143, Iss 3-4, Pp 95-

2021 Volume 97

Abstract: In the 57-year old, healthy postmenopausal female, an asymptomatic suprapubic mass was an accidental finding on a regular gynecologic ultrasound (US). In 50 days, three transabdominal US and computed tomography (CT) scans showed a rapid increase in mass ... ...

Abstract	In the 57-year old, healthy postmenopausal female, an asymptomatic suprapubic mass was an accidental finding on a regular gynecologic ultrasound (US). In 50 days, three transabdominal US and computed tomography (CT) scans showed a rapid increase in mass size (from 5.6 x 1.1 cm to 11 x 6 cm to 12.5 x 7 cm on the US, 19 x 11 cm on CT). Previous medical history noted thrombocytopenia (1 x 109/L) and an intrauterine device (IUD) with the hormonal release. The carcinoembryonic (CEA) marker was slightly elevated (4.1 IU/L). Abdominal CT with intravenous contrast revealed encapsulated mass with the intensity of fatty tissue without discernible primary origin. No signs of infiltration and invasion of surrounding structures were found. CT differential diagnosis included lipoma and low-grade liposarcoma. After exploratory laparotomy and complete extirpation of the tumor (24 x 19 x 7 cm) from the Retzius space, the histopathology confirmed a lipoma with negative estrogen and progesterone receptors. The postoperative course was uneventful, and one year after surgery, US and magnetic resonance (MR) imaging did not show recurrence.
Keywords	lipoma – diagnostic imaging ; pathology ; surgery ; pelvic neoplasms – diagnostic imaging ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2021-04-01T00:00:00Z
Publisher	Hrvatski liječnički zbor
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Single Small Bowel Hemangioma Detected by Video Capsule Endoscopy in a Patient Presenting with Iron-deficiency Anemia – Two Case Reports

Dora Grgić / Radovan Prijić / Ivan Romić / Goran Augustin / Pave Markoš / Lea Korša / Zlatko Marušić / Nadan Rustemović / Željko Krznarić

Prague Medical Report, Vol 120, Iss 4, Pp 138-

2019 Volume 143

Abstract: Hemangioma of the small intestine is a rare vascular malformation which mostly presents as occult gastrointestinal bleeding and iron-deficiency anemia. Patients are often asymptomatic except of fatigue due to anemia. Hemangiomas can arise anywhere in the ...

Abstract	Hemangioma of the small intestine is a rare vascular malformation which mostly presents as occult gastrointestinal bleeding and iron-deficiency anemia. Patients are often asymptomatic except of fatigue due to anemia. Hemangiomas can arise anywhere in the luminal gastrointestinal tract, with jejunum as the most commonly involved site. They are very hard to recognize mostly due to their localization. Video capsule endoscopy and balloon-assisted enteroscopy have very much improved preoperative diagnostics and made major contribution to establishing the diagnosis – which was very difficult in the past and almost all cases were diagnosed during or after the operation. Surgical resection is still the conventional treatment modality, although with the improvement of endoscopic therapeutic interventions (endoscopic mucosal resection, argon-plasma coagulation) there are more therapeutic possibilities.
Keywords	Anemia ; Small intestine ; Capsule endoscopy ; Occult blood ; Vascular malformation ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2019-01-01T00:00:00Z
Publisher	Karolinum Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Laparoscopic Appendectomy does not Increase the Rate of Negative Appendectomy along with a Lower Rate of Perforated Appendicitis – Results in 1899 Patients at Zagreb UHC

Goran Augustin / Zrinka Čižmešija / Jurica Žedelj / Igor Petrović / Vanja Ivković / Anko Antabak / Davor Mijatović / Mate Škegro

Acta Clinica Croatica, Vol 57, Iss 3., Pp 503-

2018 Volume 508

Abstract: Laparoscopic appendectomy is the method of choice of many professional societies owing to its many advantages. The question arises whether surgeons urge more easily to laparoscopic exploration due to its less invasiveness, faster recovery and adequate ... ...

Abstract	Laparoscopic appendectomy is the method of choice of many professional societies owing to its many advantages. The question arises whether surgeons urge more easily to laparoscopic exploration due to its less invasiveness, faster recovery and adequate exploration of the entire abdominal cavity than to observation in unequivocal cases. This retrospective analysis (2009-2016) included 1899 patients undergoing laparoscopic (lap) or gridiron intra-abdominal approach treated at Zagreb University Hospital Centre. The analysis included total negative appendectomy, negative-negative appendectomy (normal appendix and no other pathology found), and negative-positive appendectomy (normal appendix but another pathology found) in children (≤16 years) and adults. There was no statistically significant difference in the rates of negative appendectomy (children) – lap vs. open (p=0.24); negative appendectomy (adults) – lap vs. open (p=0.15); negative-negative appendectomy (children) – lap vs. open (p=0.36); negative-negative appendectomy (adults) – lap vs. open (p=0.21); negative-positive appendectomy (children) – lap vs. open (p=0.53); negative-positive appendectomy (adults) – lap vs. open (p=0.56); and laparoscopy group negative appendectomy in children vs. adults (p=0.56). There was a statistically significantly higher perforation rate with the open approach in total (p<0.0001), in children (p<0.0001) and in adults (p=0.02). There was no statistically significant difference between adults and children in the perforation rate with laparoscopic approach (p=0.24) and perforation rate with open approach (p=0.29). Results confirmed that there was no statistically significant difference in the rate of negative appendectomy in all subgroups. It is concluded that laparoscopic appendectomy should be offered as the method of choice in any patient population with suspicion of acute appendicitis.
Keywords	Appendicitis ; Appendectomy ; Laparoscopy ; Croatia ; Medicine ; R
Language	English
Publishing date	2018-01-01T00:00:00Z
Publisher	Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Suture granuloma of the abdominal wall with intra-abdominal extension 12 years after open appendectomy

Goran Augustin, Dragan Korolija, Mate Skegro, Jasminka Jakic-Razumovic

World Journal of Gastroenterology, Vol 15, Iss 32, Pp 4083-

2009 Volume 4086

Abstract: Most complications after appendectomy occur within ten days; however, we report the unusual case of a suture granuloma 12 years after open appendectomy. The afebrile 75-year-old woman presented with a slightly painful palpable mass in the right lower ... ...

Abstract	Most complications after appendectomy occur within ten days; however, we report the unusual case of a suture granuloma 12 years after open appendectomy. The afebrile 75-year-old woman presented with a slightly painful palpable mass in the right lower abdomen. There was no nausea or vomiting and bowel movements were normal. She lost 10 kg during the 3 mo before presentation. The patient had undergone an appendectomy 12 years previously. Physical examination revealed a tender mass, 10 cm in diameter, under the appendectomy scar. The preoperative laboratory findings, tumor markers and plain abdominal radiographs were normal. Multi-slice computed tomography scanning showed an inhomogenous abdominal mass with minimal vascularization in the right lower abdomen 8.6 cm × 8 cm × 9 cm in size which communicated with the abdominal wall. The abdominal wall was thickened, weak and bulging. The abdominal wall mass did not communicate with the cecum or the ascending colon. Complete excision of the abdominal wall mass was performed via median laparotomy. Histopathological examination revealed a granuloma with a central abscess. This case report demonstrates that a preoperative diagnosis of abdominal wall mass after open appendectomy warrants the use of a wide spectrum of diagnostic modalities and consequently different treatment options.
Keywords	Appendectomy ; Differential diagnosis ; Postoperative complication ; Suture granuloma ; Diseases of the digestive system. Gastroenterology ; RC799-869 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Gastroenterology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	610
Language	English
Publishing date	2009-08-01T00:00:00Z
Publisher	Baishideng Publishing Group Co. Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: SMAD7 variant rs4939827 is associated with colorectal cancer risk in Croatian population.

Iva Kirac / Petar Matošević / Goran Augustin / Iva Šimunović / Vedran Hostić / Sven Župančić / Caroline Hayward / Natasa Antoljak / Igor Rudan / Harry Campbell / Malcolm G Dunlop / Danko Velimir Vrdoljak / Dujo Kovačević / Lina Zgaga

PLoS ONE, Vol 8, Iss 9, p e

2013 Volume 74042

Abstract: Twenty common genetic variants have been associated with risk of developing colorectal cancer (CRC) in genome wide association studies to date. Since large differences between populations exist, generalisability of findings to any specific population ... ...

Abstract	Twenty common genetic variants have been associated with risk of developing colorectal cancer (CRC) in genome wide association studies to date. Since large differences between populations exist, generalisability of findings to any specific population needs to be confirmed.The aim of this study was to perform an association study between risk variants: rs10795668, rs16892766, rs3802842 and rs4939827 and CRC risk in Croatian population.An association study was performed on 320 colorectal cancer cases and 594 controls recruited in Croatia. We genotyped four variants previously associated with CRC: rs10795668, rs16892766, rs3802842 and rs4939827.SMAD7 variant rs4939827 (18q21.1) was significantly associated with CRC risk in Croatian population. C allele was associated with a decreased risk, odds ratio (OR): 0.70 (95% CI: 0.57-0.85, P=3.5E-04). Compared to TT homozygotes, risk was reduced by 34% in heterozygotes (OR=0.66, 95% CI: 0.47-0.92) and by 52% in CC homozygotes (OR=0.48, 95% CI: 0.33-0.72).Our results show association of rs4939827 with colorectal cancer risk in Croatian population. The higher strength of the association in comparison to other studies suggests population-specific environmental or genetic factors may be modifying the association. More studies are needed to further describe role of rs4939827 in CRC. Likely reason for failure of replication for other 3 loci is inadequate study power.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2013-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Colonic duplication in an adult who presented with chronic constipation attributed to hypothyroidism

Tihomir Kekez, Goran Augustin, Irena Hrstic, Dubravko Smud, Mate Majerovic, Zeljko Jelincic, Emil Kinda

World Journal of Gastroenterology, Vol 14, Iss 4, Pp 644-

2008 Volume 646

Abstract: Gastrointestinal duplications are an uncommon congenital abnormality that manifest before the age of two in 80% of cases. Ileal duplication is the most common while colonic duplication, either cystic or tubular, occurs in 10%-15% of cases and remains ... ...

Abstract	Gastrointestinal duplications are an uncommon congenital abnormality that manifest before the age of two in 80% of cases. Ileal duplication is the most common while colonic duplication, either cystic or tubular, occurs in 10%-15% of cases and remains asymptomatic and undiagnosed in most cases. Mostly occurring in pediatric patients, colonic duplication is encountered in adults in only a few cases. The most common clinical manifestations are abdominal pain and intestinal obstruction. Rarely, duplications present with signs of acute abdomen or acute bleeding. This study reports a case of colonic duplication in an adult who presented with chronic constipation. Complete diagnostic workup was made on several occasions during the previous eight year period, but no pathology was found and chronic constipation was attributed to hypothyroidism caused by long standing Hashimoto thyroiditis. Multislice CT, performed because of abdominal distension, defined colonic pathology but the definite diagnosis of duplication of the transversal colon was made at operation. The cystic duplication and the adjacent part of the ascending and transversal colon were excised en-block. This study implies that colonic duplication, though uncommon, should be included in the differential diagnosis of chronic constipation even when precipitating factors for constipation, such as hypothyroidism are present.
Keywords	Colonic duplication ; Constipation ; Abdominal distension ; Hypothyroidism ; Diseases of the digestive system. Gastroenterology ; RC799-869 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Gastroenterology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	610
Language	English
Publishing date	2008-01-01T00:00:00Z
Publisher	Baishideng Publishing Group Co. Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Erratum to: caustic ingestion management: world society of emergency surgery preliminary survey of expert opinion.

World journal of emergency surgery : WJES

2015 Volume 10, Page(s) 56

Abstract: This corrects the article DOI: 10.1186/s13017-015-0043-4.]. ...

Abstract	[This corrects the article DOI: 10.1186/s13017-015-0043-4.].
Language	English
Publishing date	2015
Publishing country	England
Document type	Published Erratum
ISSN	1749-7922
ISSN	1749-7922
DOI	10.1186/s13017-015-0050-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Caustic ingestion management: world society of emergency surgery preliminary survey of expert opinion.

World journal of emergency surgery : WJES

2015 Volume 10, Page(s) 48

Abstract: Caustic material ingestion injuries (CMI) are uncommon. Only 5,000 cases are reported in the United States each year and most acute care healthcare facilities admit only a few cases annually. Accordingly, no single institution can claim extensive ... ...

Abstract	Caustic material ingestion injuries (CMI) are uncommon. Only 5,000 cases are reported in the United States each year and most acute care healthcare facilities admit only a few cases annually. Accordingly, no single institution can claim extensive experience, and management protocols are most probably based on either expert opinion or literature reports. In this study, we will attempt to review opinions and practices of representatives of the board members of the World Society of Emergency Surgery and compare them to the current literature.
Language	English
Publishing date	2015
Publishing country	England
Document type	Journal Article
ISSN	1749-7922
ISSN	1749-7922
DOI	10.1186/s13017-015-0043-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A pandemic recap

Federico Coccolini / Enrico Cicuttin / Camilla Cremonini / Dario Tartaglia / Bruno Viaggi / Akira Kuriyama / Edoardo Picetti / Chad Ball / Fikri Abu-Zidan / Marco Ceresoli / Bruno Turri / Sumita Jain / Carlo Palombo / Xavier Guirao / Gabriel Rodrigues / Mahir Gachabayov / Fernando Machado / Lostoridis Eftychios / Souha S. Kanj /

Isidoro Di Carlo / Salomone Di Saverio / Vladimir Khokha / Andrew Kirkpatrick / Damien Massalou / Francesco Forfori / Francesco Corradi / Samir Delibegovic / Gustavo M. Machain Vega / Massimo Fantoni / Demetrios Demetriades / Garima Kapoor / Yoram Kluger / Shamshul Ansari / Ron Maier / Ari Leppaniemi / Timothy Hardcastle / Andras Vereczkei / Evika Karamagioli / Emmanouil Pikoulis / Mauro Pistello / Boris E. Sakakushev / Pradeep H. Navsaria / Rita Galeiras / Ali I. Yahya / Aleksei V. Osipov / Evgeni Dimitrov / Krstina Doklestić / Michele Pisano / Paolo Malacarne / Paolo Carcoforo / Maria Grazia Sibilla / Igor A. Kryvoruchko / Luigi Bonavina / Jae Il Kim / Vishal G. Shelat / Jacek Czepiel / Emilio Maseda / Sanjay Marwah / Mircea Chirica / Giandomenico Biancofiore / Mauro Podda / Lorenzo Cobianchi / Luca Ansaloni / Paola Fugazzola / Charalampos Seretis / Carlos Augusto Gomez / Fabio Tumietto / Manu Malbrain / Martin Reichert / Goran Augustin / Bruno Amato / Alessandro Puzziello / Andreas Hecker / Angelo Gemignani / Arda Isik / Alessandro Cucchetti / Mirco Nacoti / Doron Kopelman / Cristian Mesina / Wagih Ghannam / Offir Ben-Ishay / Sameer Dhingra / Raul Coimbra / Ernest E. Moore / Yunfeng Cui / Martha A. Quiodettis / Miklosh Bala / Mario Testini / Jose Diaz / Massimo Girardis / Walter L. Biffl / Matthias Hecker / Ibrahima Sall / Ugo Boggi / Gabriele Materazzi / Lorenzo Ghiadoni / Junichi Matsumoto / Wietse P. Zuidema / Rao Ivatury / Mushira A. Enani / Andrey Litvin / Majdi N. Al-Hasan / Zaza Demetrashvili / Oussama Baraket / Carlos A. Ordoñez / Ionut Negoi / Ronald Kiguba / Ziad A. Memish / Mutasim M. Elmangory / Matti Tolonen / Korey Das / Julival Ribeiro / Donal B. O’Connor / Boun Kim Tan / Harry Van Goor / Suman Baral / Belinda De Simone / Davide Corbella / Pietro Brambillasca / Michelangelo Scaglione / Fulvio Basolo / Nicola De’Angelis / Cino Bendinelli / Dieter Weber / Leonardo Pagani / Cinzia Monti / Gianluca Baiocchi / Massimo Chiarugi / Fausto Catena / Massimo Sartelli

World Journal of Emergency Surgery, Vol 16, Iss 1, Pp 1-

lessons we have learned

2021 Volume 8

Abstract: Abstract On January 2020, the WHO Director General declared that the outbreak constitutes a Public Health Emergency of International Concern. The world has faced a worldwide spread crisis and is still dealing with it. The present paper represents a white ...

Abstract	Abstract On January 2020, the WHO Director General declared that the outbreak constitutes a Public Health Emergency of International Concern. The world has faced a worldwide spread crisis and is still dealing with it. The present paper represents a white paper concerning the tough lessons we have learned from the COVID-19 pandemic. Thus, an international and heterogenous multidisciplinary panel of very differentiated people would like to share global experiences and lessons with all interested and especially those responsible for future healthcare decision making. With the present paper, international and heterogenous multidisciplinary panel of very differentiated people would like to share global experiences and lessons with all interested and especially those responsible for future healthcare decision making.
Keywords	Pandemia ; International ; Thoughts ; Reflection ; Ethics ; Biology ; Surgery ; RD1-811 ; Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9
Subject code	360
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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