Article ; Online: Different responses of repetitive behaviours in juvenile and young adult mice to Δ
British journal of pharmacology
2020 Volume 178, Issue 3, Page(s) 614–625
Abstract: Background and purpose: Medicinal cannabis is in increasing use by patients with Tourette syndrome, a neuropsychiatric disorder that affects about 1% of the general population and has a childhood onset. However, the pharmacological effects of Δ: ... ...
| Abstract | Background and purpose: Medicinal cannabis is in increasing use by patients with Tourette syndrome, a neuropsychiatric disorder that affects about 1% of the general population and has a childhood onset. However, the pharmacological effects of Δ Experimental approach: The administration of 2,5-dimethoxy-4-iodoamphetamine (DOI) increases head twitch response (HTR) and ear scratch response (ESR) and has been proposed as an animal model useful to respectively study motor tics and premonitory urges associated with tic disorders. Key results: Comparing the potency of Δ Conclusion and implications: Δ |
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| MeSH term(s) | Animals ; Cannabidiol/pharmacology ; Child ; Decision Making ; Dronabinol/pharmacology ; Humans ; Medical Marijuana ; Mice ; Tourette Syndrome/drug therapy |
| Chemical Substances | Medical Marijuana ; Cannabidiol (19GBJ60SN5) ; Dronabinol (7J8897W37S) |
| Language | English |
| Publishing date | 2020-12-02 |
| Publishing country | England |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 80081-8 |
| ISSN | 1476-5381 ; 0007-1188 |
| ISSN (online) | 1476-5381 |
| ISSN | 0007-1188 |
| DOI | 10.1111/bph.15302 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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