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  1. Article: Analiz opyta primeneniya nazal'nykh kateterov pri ostrom bakterial'nom rinosinusite.

    Kozlov, V S / Gorbunov, S A / Kudryashov, S E

    Vestnik otorinolaringologii

    2021  Volume 85, Issue 6, Page(s) 46–51

    Abstract: The number of cases of acute bacterial rhinosinusitis (ABRS) in our country tends to increase. According to clinical guidelines of the Ministry of Health of the Russian Federation, nasal catheter drainage is used to treat ABRS, but not all ENT-doctors ... ...

    Title translation An analysis of experience of using nasal catheters in acute bacterial rhinosinusitis.
    Abstract The number of cases of acute bacterial rhinosinusitis (ABRS) in our country tends to increase. According to clinical guidelines of the Ministry of Health of the Russian Federation, nasal catheter drainage is used to treat ABRS, but not all ENT-doctors use this method in daily practice. Many of them use it empirically and obtain good results.
    Goal: To study the experience of ENT-doctors using the YAMIK nasal catheter (NC) in their clinical practice.
    Material and methods: To achieve the goal, a 16-question questionnaire was developed. Further, a survey of 30 ENT-doctors was conducted via e-mail.
    Results and discussion: The study showed a marked dispersion of data regarding the time of starting therapy, the number of necessary procedures, as well as the components of medication solutions administered to the paranasal sinuses. At the same time, the effectiveness of the method, in doctors' opinion, is very high (above 90%). The incorrect technique of NC application, absence of studies according to the principles of Good Clinical Practice (GCP), and constructive disadvantages of NC may be probable reasons for the method undervaluation.
    Conclusions: The prescription of procedures with NC to patients with ABRS is empirical and is probably related to the absence of clear indications for such treatment, data on its duration, and associated therapy. Consequently, research following GCP principles is required to develop an algorithm for treating ABSR with an NC. The development of a new design for an NC that will allow each ENT-doctor to learn the method is also appropriate.
    MeSH term(s) Catheters ; Humans ; Paranasal Sinuses ; Rhinitis/diagnosis ; Rhinitis/therapy ; Russia ; Sinusitis/diagnosis ; Sinusitis/therapy
    Language Russian
    Publishing date 2021-01-20
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 124096-1
    ISSN 0042-4668
    ISSN 0042-4668
    DOI 10.17116/otorino20208506146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Evolyutsiya metodov aktivnogo drenirovaniya okolonosovykh pazukh pri rinosinusite. Chast' 1.

    Gorbunov, S A / Rusetsky, Yu Yu / Kudryashov, S E / Malyavina, U S

    Vestnik otorinolaringologii

    2021  Volume 86, Issue 3, Page(s) 110–117

    Abstract: Inflammation of the paranasal sinuses significantly reduces the quality of life of people and causes marked economic damage to society. The striking clinical picture of sinusitis has always forced doctors to study the disease, as evidenced by the first ... ...

    Title translation The evolution of methods of active irrigation of paranasal sinuses in rhinosinusitis. Part 1.
    Abstract Inflammation of the paranasal sinuses significantly reduces the quality of life of people and causes marked economic damage to society. The striking clinical picture of sinusitis has always forced doctors to study the disease, as evidenced by the first records of the anatomy and diseases of the paranasal sinuses by doctors in ancient Egypt more than 3.000 years BC. Sinusitis has been treated in different ways in different historical periods. Effective medication treatment appeared relatively recently and began to steadily replace the older instrumental methods, to which many people had a preconceived notion of invasiveness. However, many studies are showing the positive effect of active drainage methods and, moreover, there is data showing that the discomfort during such procedures is slightly higher than during dental treatment under local anesthesia. This article presents a review of the available scientific literature on the use of different treatments for bacterial rhinosinusitis at different historical stages, ranging from the first publications on puncture techniques to balloon dilatation and the modern approach to conservative treatment.
    MeSH term(s) Chronic Disease ; Endoscopy ; Humans ; Paranasal Sinuses ; Quality of Life ; Rhinitis/diagnosis ; Rhinitis/therapy ; Sinusitis/diagnosis ; Sinusitis/therapy ; Therapeutic Irrigation
    Language Russian
    Publishing date 2021-07-15
    Publishing country Russia (Federation)
    Document type Journal Article ; Review
    ZDB-ID 124096-1
    ISSN 0042-4668
    ISSN 0042-4668
    DOI 10.17116/otorino202186031110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Evolyutsiya metodov aktivnogo drenirovaniya okolonosovykh pazukh pri rinosinusite. Chast' 2.

    Gorbunov, S A / Rusetsky, Yu Yu / Kudryashov, S E / Malyavina, U S

    Vestnik otorinolaringologii

    2021  Volume 86, Issue 4, Page(s) 99–105

    Abstract: Inflammation of the paranasal sinuses significantly reduces the quality of life of people and causes marked economic damage to society. The striking clinical picture of sinusitis has always forced doctors to study the disease, as evidenced by the first ... ...

    Title translation The evolution of methods of active irrigation of paranasal sinuses in rhinosinusitis. Part 2.
    Abstract Inflammation of the paranasal sinuses significantly reduces the quality of life of people and causes marked economic damage to society. The striking clinical picture of sinusitis has always forced doctors to study the disease, as evidenced by the first records of the anatomy and diseases of the paranasal sinuses by doctors in ancient Egypt more than 3.000 years BC. Sinusitis has been treated in different ways in different historical periods. Effective medication treatment appeared relatively recently and began to steadily replace the older instrumental methods, to which many people had a preconceived notion of invasiveness. However, many studies are showing the positive effect of active drainage methods and, moreover, there is data showing that the discomfort during such procedures is slightly higher than during dental treatment under local anesthesia. This article presents a review of the available scientific literature on the use of different treatments for bacterial rhinosinusitis at different historical stages, ranging from the first publications on puncture techniques to balloon dilatation and the modern approach to conservative treatment.
    MeSH term(s) Chronic Disease ; Humans ; Paranasal Sinuses ; Quality of Life ; Rhinitis/diagnosis ; Rhinitis/therapy ; Sinusitis/diagnosis ; Sinusitis/therapy
    Language Russian
    Publishing date 2021-09-09
    Publishing country Russia (Federation)
    Document type Journal Article ; Review
    ZDB-ID 124096-1
    ISSN 0042-4668
    ISSN 0042-4668
    DOI 10.17116/otorino20218604199
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Dependence of track etching kinetics on chemical reactivity around the ion path.

    Gorbunov, S A / Rymzhanov, R A / Volkov, A E

    Scientific reports

    2019  Volume 9, Issue 1, Page(s) 15325

    Abstract: Etching kinetics of swift heavy ions (SHI) tracks in olivine is investigated in frame of experimentally verified numerical approach. The model takes into account variation of induced chemical reactivity of the material around the whole ion trajectory ... ...

    Abstract Etching kinetics of swift heavy ions (SHI) tracks in olivine is investigated in frame of experimentally verified numerical approach. The model takes into account variation of induced chemical reactivity of the material around the whole ion trajectory with the nanometric accuracy. This enables a quantitative description of wet chemical etching of SHI tracks of different lengths and orientations towards to the sample surface. It is demonstrated that two different modes of etching, governed by diffusion of etchant molecules and by their reaction with the material must be observed in experiments using techniques with different resolution thresholds. Applicability limits of the optical microscopy for detection of heavy ion parameters by measuring of the lengthwise etching rates of the ion track are discussed.
    Language English
    Publishing date 2019-10-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-019-51748-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Éffektivnost' lokal'noĭ terapii pri ostrykh vospalitel'nykh zabolevaniiakh verkhnikh dykhatel'nykh puteĭ.

    Kozlov, V S / Savlevich, E L / Gorbunov, S A / Felshin, D I

    Vestnik otorinolaringologii

    2020  Volume 85, Issue 1, Page(s) 68–73

    Abstract: Acute bacterial rhinosinusitis (ABRS) is one of the most common diseases in outpatient practice with a steady tendency to increase of complicated forms in recent years. The risk of antibiotic resistance makes it necessary to search for effective ... ...

    Title translation The effectiveness of local therapy of acute inflammatory diseases of the upper respiratory tract.
    Abstract Acute bacterial rhinosinusitis (ABRS) is one of the most common diseases in outpatient practice with a steady tendency to increase of complicated forms in recent years. The risk of antibiotic resistance makes it necessary to search for effective pathogenetic methods of ABRS treatment.
    Objective: To evaluate the efficacy of inhalation therapy with compressor nebulizer using Fluimucil Antibiotic IT in the treatment of ABRS and acute laryngotracheitis in outpatient practice.
    Material and methods: Patients with ABRS were divided into two sex- and age-matched groups of 26 people each. The first group was treated with 250 mg of Fluimucil Antibiotic IT inhalations by the use of Norditalia HI-NEB compressor nebulizer once a day. The second group was treated with amoxicillin/clavulanate 875 mg + 125 mg orally two times a day.
    Results: In the first group, the cough disappeared significantly earlier (on day 5-6) than in the second group (on day 7-8). In the first group, nasal congestion also disappeared significantly earlier (on day 3-5) than in the second group (on day 4-6). There was no significant difference in the reduction of intoxication syndrome and nasal secretions in both groups.
    Conclusion: Local antibacterial and mucolytic therapy in the initial stages of ABRS and acute laryngotracheitis reduces rhinological symptoms and coughing, similar to systemic antibacterial therapy. The use of Fluimucil Antibiotic IT in the early stages of the treatment provides an opportunity to avoid systemic antibiotics, which reduces the risk of antibiotic resistance as well as side effects in patients.
    MeSH term(s) Acute Disease ; Anti-Bacterial Agents/therapeutic use ; Humans ; Rhinitis/drug therapy ; Sinusitis/drug therapy ; Trachea
    Chemical Substances Anti-Bacterial Agents
    Language Russian
    Publishing date 2020-03-30
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 124096-1
    ISSN 0042-4668
    ISSN 0042-4668
    DOI 10.17116/otorino20208501168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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