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  1. Article ; Online: Correction to: Does the uterine microbiota affect the reproductive outcomes in women with recurrent implantation failures?

    Keburiya, Lela K / Smolnikova, Veronika Yu / Priputnevich, Tatiana V / Muravieva, Vera V / Gordeev, Alexey B / Trofimov, Dmitry Yu / Shubina, Ekaterina S / Kochetkova, Taisiya O / Rogacheva, Margarita S / Kalinina, Elena A / Sukhikh, Gennady T

    BMC women's health

    2023  Volume 23, Issue 1, Page(s) 265

    Language English
    Publishing date 2023-05-15
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2050444-5
    ISSN 1472-6874 ; 1472-6874
    ISSN (online) 1472-6874
    ISSN 1472-6874
    DOI 10.1186/s12905-023-02302-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Modeling of folds and folding pathways for some protein families of (α + β)- and (α/β)-classes.

    Gordeev, Alexey B / Efimov, Alexander V

    Journal of biomolecular structure & dynamics

    2013  Volume 31, Issue 1, Page(s) 4–16

    Abstract: In this paper, updated structural trees for α/β-proteins containing five- and seven-segment (α/β)-motifs are represented. Novel structural motifs occurring in some families of (α + β)- and (α/β)-proteins are also characterized. Databases of these ... ...

    Abstract In this paper, updated structural trees for α/β-proteins containing five- and seven-segment (α/β)-motifs are represented. Novel structural motifs occurring in some families of (α + β)- and (α/β)-proteins are also characterized. Databases of these proteins have been compiled from the Protein Data Bank (PDB) and Structural Classification of Proteins (SCOP) and the corresponding structural trees have been constructed. The classification of these proteins has been developed and organized as an extension of the PCBOST database, which is available at http://strees.protres.ru . In total, the updated Protein Classification Based on Structural Trees database contains 11 structural trees, 106 levels, 635 folds, 4911 proteins and domains, and 14,202 PDB entries.
    MeSH term(s) Databases, Factual ; Databases, Protein ; Models, Molecular ; Protein Conformation ; Protein Folding ; Proteins/chemistry ; Proteins/classification
    Chemical Substances Proteins
    Language English
    Publishing date 2013
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2012.691341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The novel coronavirus SARS-COV-2 and pregnancy: Literature review

    Priputnevich, Tatiana V. / Gordeev, Alexey B. / Lyubasovskaya, Lyudmila A. / Shabanova, Natalia E.

    Akush. Ginekol.

    Abstract: Having emerged in China, the new coronavirus SARS-CoV-2 has spread rapidly worldwide. Pregnant women are patients who have risk factors for severe/complicated acute respiratory viral infections and influenza; however, there have been presently only few ... ...

    Abstract Having emerged in China, the new coronavirus SARS-CoV-2 has spread rapidly worldwide. Pregnant women are patients who have risk factors for severe/complicated acute respiratory viral infections and influenza; however, there have been presently only few works that highlight the specific features of the course of COVID-19, a disease caused by the novel coronavirus SARS-CoV-2, in pregnant women and newborns. The aim of the review was to search for and analyze publications considering the characteristics of the course of COVID-19 in pregnant women and newborns. Pregnancy and childbirth do not seem to aggravate the course of COVID-19; on the contrary, the latter can deteriorate the course of pregnancy: it can cause respiratory distress syndrome and lead to premature birth and miscarriage. There is no current evidence for mother-to-fetus placental transmission of COVID-19 and mother-to-baby transmission during breastfeeding. A large number of interim guidelines for the management of pregnant women with COVID-19 have been published.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #626520
    Database COVID19

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  4. Article ; Online: Does the uterine microbiota affect the reproductive outcomes in women with recurrent implantation failures?

    Keburiya, Lela K / Smolnikova, Veronika Yu / Priputnevich, Tatiana V / Muravieva, Vera V / Gordeev, Alexey B / Trofimov, Dmitry Yu / Shubina, Ekaterina S / Kochetkova, Taisiya O / Rogacheva, Margarita S / Kalinina, Elena A / Sukhikh, Gennady T

    BMC women's health

    2022  Volume 22, Issue 1, Page(s) 168

    Abstract: Background: Inefficiency of in vitro fertilization (IVF) programs can be caused by implantation failures. The uterine microbiota can influence the implantation process. However, it still remains unclear whether opportunistic microorganisms detected in ... ...

    Abstract Background: Inefficiency of in vitro fertilization (IVF) programs can be caused by implantation failures. The uterine microbiota can influence the implantation process. However, it still remains unclear whether opportunistic microorganisms detected in the endometrium have a negative impact on the implantation success. The aim of our study was to evaluate the influence of the uterine microbiota on the embryo implantation success in patients undergoing assisted reproductive technologies.
    Methods: The study included 130 women diagnosed with infertility. The patients were divided into three groups: group I included women with the first IVF attempt (n = 39); group II included patients with recurrent implantation failure following embryo transfer with ovarian stimulation (n = 27); group III consisted of women with recurrent implantation failure following frozen-thawed embryo transfer (n = 64). We performed microbiological examination of the embryo transfer catheter which was removed from the uterine cavity after embryo transfer; cervical discharge of all the patients was studied as well. Thirty patients were selected for metagenomic sequencing.
    Results: The study showed that the uterine cavity is not free of microorganisms. A total of 44 species of microorganisms were detected: 26 species of opportunistic organisms and 18 species of commensals (14 species of lactobacilli and 4 species of bifidobacteria). Obligate anaerobic microorganisms and Gardnerella vaginalis were detected more frequently in group I compared to group III (strict anaerobes-15.4 and 1.6%; G. vaginalis-12.8 and 1.6%, respectively) (p < 0.05). However, this fact did not have a negative influence on the pregnancy rate: it was 51.3% in group I, it was 29.6% and 35.9% in women with recurrent implantation failures, respectively.
    Conclusion: Opportunistic microorganisms which were revealed in low or moderate titers (10
    MeSH term(s) Embryo Implantation ; Embryo Transfer ; Female ; Fertilization in Vitro ; Humans ; Microbiota ; Pregnancy ; Pregnancy Rate
    Language English
    Publishing date 2022-05-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2050444-5
    ISSN 1472-6874 ; 1472-6874
    ISSN (online) 1472-6874
    ISSN 1472-6874
    DOI 10.1186/s12905-022-01750-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A novel structural tree for wrap-proteins, a subclass of (α+β)-proteins.

    Boshkova, Eugenia A / Gordeev, Alexey B / Efimov, Alexander V

    Journal of biomolecular structure & dynamics

    2014  Volume 32, Issue 2, Page(s) 222–225

    Abstract: In this paper, a novel structural subclass of (α+β)-proteins is presented. A characteristic feature of these proteins and domains is that they consist of strongly twisted and coiled β-sheets wrapped around one or two α-helices, so they are referred to ... ...

    Abstract In this paper, a novel structural subclass of (α+β)-proteins is presented. A characteristic feature of these proteins and domains is that they consist of strongly twisted and coiled β-sheets wrapped around one or two α-helices, so they are referred to here as wrap-proteins. It is shown that overall folds of the wrap-proteins can be obtained by stepwise addition of α-helices and/or β-strands to the strongly twisted and coiled β-hairpin taken as the starting structure in modeling. As a result of modeling, a structural tree for the wrap-proteins was constructed that includes 201 folds of which 49 occur in known nonhomologous proteins.
    MeSH term(s) Databases, Protein ; Models, Molecular ; Protein Conformation ; Protein Folding ; Protein Structure, Tertiary ; Proteins/chemistry ; Proteins/ultrastructure
    Chemical Substances Proteins
    Language English
    Publishing date 2014
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2012.760107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Limosilactobacillus fermentum

    Abramov, Vyacheslav M / Kosarev, Igor V / Machulin, Andrey V / Priputnevich, Tatiana V / Deryusheva, Evgenia I / Nemashkalova, Ekaterina L / Chikileva, Irina O / Abashina, Tatiana N / Panin, Alexander N / Melnikov, Vyacheslav G / Suzina, Nataliya E / Nikonov, Ilia N / Selina, Marina V / Khlebnikov, Valentin S / Sakulin, Vadim K / Samoilenko, Vladimir A / Gordeev, Alexey B / Sukhikh, Gennady T / Uversky, Vladimir N /
    Karlyshev, Andrey V

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 3

    Abstract: LF3872 was isolated from the milk of a healthy lactating and breastfeeding woman. Earlier, the genome of LF3872 was sequenced, and a gene encoding unique bacteriocin was discovered. We have shown here that the LF3872 strain produces a novel thermolabile ... ...

    Abstract LF3872 was isolated from the milk of a healthy lactating and breastfeeding woman. Earlier, the genome of LF3872 was sequenced, and a gene encoding unique bacteriocin was discovered. We have shown here that the LF3872 strain produces a novel thermolabile class III bacteriolysin (BLF3872), exhibiting antimicrobial activity against antibiotic-resistant
    Language English
    Publishing date 2023-02-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12030471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Ligilactobacillus salivarius

    Abramov, Vyacheslav M / Kosarev, Igor V / Machulin, Andrey V / Deryusheva, Evgenia I / Priputnevich, Tatiana V / Panin, Alexander N / Chikileva, Irina O / Abashina, Tatiana N / Manoyan, Ashot M / Ahmetzyanova, Anna A / Ivanova, Olga E / Papazyan, Tigran T / Nikonov, Ilia N / Suzina, Nataliya E / Melnikov, Vyacheslav G / Khlebnikov, Valentin S / Sakulin, Vadim K / Samoilenko, Vladimir A / Gordeev, Alexey B /
    Sukhikh, Gennady T / Uversky, Vladimir N

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 10

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2023-10-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12101535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Protective Properties of S-layer Protein 2 from

    Abramov, Vyacheslav M / Kosarev, Igor V / Machulin, Andrey V / Priputnevich, Tatiana V / Deryusheva, Evgenia I / Panin, Alexander N / Chikileva, Irina O / Abashina, Tatiana N / Melnikov, Vyacheslav G / Suzina, Nataliya E / Nikonov, Ilia N / Akhmetzyanova, Anna A / Khlebnikov, Valentin S / Sakulin, Vadim K / Vasilenko, Raisa N / Samoilenko, Vladimir A / Gordeev, Alexey B / Sukhikh, Gennady T / Uversky, Vladimir N /
    Karlyshev, Andrey V

    Biomolecules

    2023  Volume 13, Issue 12

    Abstract: Previously, the protective role of the S-layer protein 2 (Slp2) of the ... ...

    Abstract Previously, the protective role of the S-layer protein 2 (Slp2) of the vaginal
    MeSH term(s) Female ; Humans ; Lactobacillus crispatus ; Candida albicans ; HeLa Cells ; Candidiasis ; Epithelial Cells/metabolism
    Language English
    Publishing date 2023-12-04
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom13121740
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: PCBOST: Protein classification based on structural trees.

    Gordeev, Alexey B / Kargatov, Anton M / Efimov, Alexander V

    Biochemical and biophysical research communications

    2010  Volume 397, Issue 3, Page(s) 470–471

    Abstract: In this paper, we present the protein classification based on structural trees (PCBOST). This is a novel hierarchical classification of proteins that is primarily based on similarity of overall folds of proteins as well as on the modeled folding pathways ...

    Abstract In this paper, we present the protein classification based on structural trees (PCBOST). This is a novel hierarchical classification of proteins that is primarily based on similarity of overall folds of proteins as well as on the modeled folding pathways of proteins. Amino acid sequences, functions of proteins and their evolutionary relationship are not taken into account in this classification. To date the database includes 3847 proteins and domains grouped into six categories having structural similarity and forming six structural trees (total 10,547 PDB-entries). The work on extension of the database and construction of novel structural trees is in progress. The service is free for all users and available at the URL <http://strees.protres.ru/>.
    MeSH term(s) Amino Acid Sequence ; Databases, Protein ; Evolution, Molecular ; Models, Molecular ; Protein Conformation ; Protein Folding ; Proteins/chemistry ; Proteins/classification
    Chemical Substances Proteins
    Language English
    Publishing date 2010-07-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2010.05.136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Anti-

    Abramov, Vyacheslav M / Kosarev, Igor V / Machulin, Andrey V / Deryusheva, Evgenia I / Priputnevich, Tatiana V / Panin, Alexander N / Chikileva, Irina O / Abashina, Tatiana N / Manoyan, Ashot M / Akhmetzyanova, Anna A / Blumenkrants, Dmitriy A / Ivanova, Olga E / Papazyan, Tigran T / Nikonov, Ilia N / Suzina, Nataliya E / Melnikov, Vyacheslav G / Khlebnikov, Valentin S / Sakulin, Vadim K / Samoilenko, Vladimir A /
    Gordeev, Alexey B / Sukhikh, Gennady T / Uversky, Vladimir N / Karlyshev, Andrey V

    Antibiotics (Basel, Switzerland)

    2023  Volume 13, Issue 1

    Abstract: Limosilactobacillus ... ...

    Abstract Limosilactobacillus fermentum
    Language English
    Publishing date 2023-12-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics13010030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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