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  1. Article ; Online: Progressive myocardial dysfunction following COVID-19.

    Gorecka, Miroslawa Maria / Thirunavukarasu, Sharmaine / Levelt, Eylem / Greenwood, John P

    BMJ case reports

    2021  Volume 14, Issue 11

    MeSH term(s) COVID-19 ; Cardiomyopathies ; Humans ; SARS-CoV-2 ; Ventricular Function, Left
    Language English
    Publishing date 2021-11-11
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-246291
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Unusual cause of pericardial effusion: IgG4-related disease.

    Gorecka, Miroslawa Maria / Armstrong, Richard / Daly, Caroline

    BMJ case reports

    2019  Volume 12, Issue 6

    MeSH term(s) Antirheumatic Agents/administration & dosage ; Biopsy/methods ; Contrast Media/pharmacology ; Echocardiography/methods ; Female ; Gadolinium/pharmacology ; Humans ; Image Enhancement/methods ; Immunoglobulin G4-Related Disease/complications ; Immunoglobulin G4-Related Disease/diagnosis ; Immunoglobulin G4-Related Disease/drug therapy ; Immunoglobulin G4-Related Disease/immunology ; Magnetic Resonance Imaging, Cine/methods ; Middle Aged ; Pericardial Effusion/diagnosis ; Pericardial Effusion/etiology ; Pericardium/diagnostic imaging ; Pericardium/pathology ; Rituximab/administration & dosage ; Treatment Outcome
    Chemical Substances Antirheumatic Agents ; Contrast Media ; Rituximab (4F4X42SYQ6) ; Gadolinium (AU0V1LM3JT)
    Language English
    Publishing date 2019-06-29
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-230505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: When your immune system falls out with your heart: an important lesson on antisynthetase myocarditis.

    Gorecka, Miroslawa Maria / Tummon, Olga / Smyth, Yvonne / O'Regan, Anthony

    BMJ case reports

    2018  Volume 2018

    Abstract: A 57-year-old special Olympics athlete presented with subacute onset dyspnoea. Baseline investigations revealed troponin T rise and an abnormal ECG, which prompted coronary angiography. This was unremarkable, as was his transthoracic echocardiography ( ... ...

    Abstract A 57-year-old special Olympics athlete presented with subacute onset dyspnoea. Baseline investigations revealed troponin T rise and an abnormal ECG, which prompted coronary angiography. This was unremarkable, as was his transthoracic echocardiography (TTE). He re-presented 7 months later with progressive dyspnoea associated with significant weight loss, peripheral oedema and intermittent fevers. Examination revealed bilateral fine end-inspiratory crackles, peripheral oedema and fever. Investigations revealed elevated troponin T and raised inflammatory markers. ECG remained unchanged, whereas TTE revealed mild global impairment of left ventricular function. Chest radiography was suggestive of extensive interstitial lung disease, which was confirmed by high resolution CT. Presence of interstitial lung disease and myocarditis raised the suspicion of a systemic inflammatory condition. Subsequently, an autoimmune screen was positive for anti-Jo-1 antibody associated with antisynthetase syndrome. He was treated with high-dose steroids and rituximab with dramatic symptomatic improvement and immediate fall in troponin T level.
    MeSH term(s) Athletes ; Diagnosis, Differential ; Drug Therapy, Combination ; Dyspnea/etiology ; Echocardiography, Transesophageal ; Electrocardiography ; Humans ; Immunologic Factors/administration & dosage ; Immunologic Factors/therapeutic use ; Lung Diseases, Interstitial/blood ; Lung Diseases, Interstitial/complications ; Lung Diseases, Interstitial/diagnosis ; Lung Diseases, Interstitial/drug therapy ; Male ; Middle Aged ; Myocarditis/blood ; Myocarditis/complications ; Myocarditis/diagnosis ; Myocarditis/drug therapy ; Myositis/blood ; Myositis/complications ; Myositis/diagnosis ; Myositis/drug therapy ; Prednisone/administration & dosage ; Prednisone/therapeutic use ; Rituximab/administration & dosage ; Rituximab/therapeutic use ; Troponin T/blood
    Chemical Substances Immunologic Factors ; Troponin T ; Rituximab (4F4X42SYQ6) ; Prednisone (VB0R961HZT)
    Language English
    Publishing date 2018-08-29
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2018-226019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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