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  1. Book: Neuropsychiatric genetic syndromes

    Gothelf, Doron

    (Child and adolescent psychiatric clinics of North America ; 16,3)

    2007  

    Author's details guest ed. Doron Gothelf
    Series title Child and adolescent psychiatric clinics of North America ; 16,3
    Collection
    Language English
    Size XX S., S. 541 - 749 : Ill.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015241654
    ISBN 1-4160-5044-2 ; 978-1-4160-5044-5
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Unexpected mental health improvement in children and adolescents during COVID-19-who benefits from staying at home?

    Hertz-Palmor, Nimrod / Gothelf, Doron

    European child & adolescent psychiatry

    2024  Volume 33, Issue 5, Page(s) 1235–1237

    MeSH term(s) Humans ; COVID-19/psychology ; COVID-19/prevention & control ; Child ; Adolescent ; Mental Health ; SARS-CoV-2 ; Mental Disorders/therapy
    Language English
    Publishing date 2024-05-15
    Publishing country Germany
    Document type Letter ; Editorial
    ZDB-ID 1118299-4
    ISSN 1435-165X ; 1018-8827 ; 1433-5719
    ISSN (online) 1435-165X
    ISSN 1018-8827 ; 1433-5719
    DOI 10.1007/s00787-024-02432-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lymphoblast transcriptome analysis in 22q11.2 deletion syndrome individuals with schizophrenia-spectrum disorder.

    Michaelovsky, Elena / Carmel, Miri / Gothelf, Doron / Weizman, Abraham

    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

    2024  Volume 25, Issue 4, Page(s) 242–254

    Abstract: Objectives: 22q11.2 deletion is the most prominent risk factor for schizophrenia (SZ). The aim of the present study was to identify unique transcriptome profile for 22q11.2 deletion syndrome (DS)-related SZ-spectrum disorder (SZ-SD).: Methods: We ... ...

    Abstract Objectives: 22q11.2 deletion is the most prominent risk factor for schizophrenia (SZ). The aim of the present study was to identify unique transcriptome profile for 22q11.2 deletion syndrome (DS)-related SZ-spectrum disorder (SZ-SD).
    Methods: We performed RNA-Seq screening in lymphoblasts collected from 20 individuals with 22q11.2DS (10 men and 10 women, four of each sex with SZ-SD and six with no psychotic disorders (Np)).
    Results: Sex effect in RNA-Seq descriptive analysis led to separating the analyses between men and women. In women, only one differentially expressed gene (DEG),
    Conclusions: Candidate pathways and upstream regulators may serve as novel biomarkers and treatment targets for SZ. Future transcriptome studies, including larger samples and proteomic analysis, are needed to substantiate our findings.
    MeSH term(s) Humans ; Female ; Schizophrenia/genetics ; Male ; DiGeorge Syndrome/genetics ; Adult ; Gene Expression Profiling ; Lymphocytes/metabolism ; Transcriptome ; Young Adult ; RNA-Seq ; Sex Factors
    Language English
    Publishing date 2024-05-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2051402-5
    ISSN 1814-1412 ; 1562-2975
    ISSN (online) 1814-1412
    ISSN 1562-2975
    DOI 10.1080/15622975.2024.2327030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The importance of measuring quality of life as a treatment outcome in child and adolescent psychiatry.

    Hertz-Palmor, Nimrod / Gothelf, Doron

    European child & adolescent psychiatry

    2022  Volume 31, Issue 9, Page(s) 1331–1335

    MeSH term(s) Adolescent ; Adolescent Psychiatry ; Child ; Child Psychiatry ; Family ; Humans ; Quality of Life ; Treatment Outcome
    Language English
    Publishing date 2022-08-04
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1118299-4
    ISSN 1435-165X ; 1018-8827 ; 1433-5719
    ISSN (online) 1435-165X
    ISSN 1018-8827 ; 1433-5719
    DOI 10.1007/s00787-022-02058-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Rethinking the role of technology-assisted cognitive behavioral therapy for youth in the post-COVID-19 era.

    de la Fontaine, Naama / Tsafrir, Shlomit / Gothelf, Doron

    European child & adolescent psychiatry

    2023  Volume 32, Issue 4, Page(s) 545–547

    MeSH term(s) Humans ; Adolescent ; COVID-19 ; Cognitive Behavioral Therapy
    Language English
    Publishing date 2023-04-06
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1118299-4
    ISSN 1435-165X ; 1018-8827 ; 1433-5719
    ISSN (online) 1435-165X
    ISSN 1018-8827 ; 1433-5719
    DOI 10.1007/s00787-023-02203-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Minding the gap between clinical guidelines and real-life clinical work.

    Balan-Moshe, Livia / Gothelf, Doron

    European child & adolescent psychiatry

    2021  Volume 30, Issue 5, Page(s) 681–683

    Language English
    Publishing date 2021-03-31
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1118299-4
    ISSN 1435-165X ; 1018-8827 ; 1433-5719
    ISSN (online) 1435-165X
    ISSN 1018-8827 ; 1433-5719
    DOI 10.1007/s00787-021-01765-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Changes in Symptom Severity among Children and Adolescents with Obsessive-Compulsive Disorder during the COVID-19 Pandemic: A 2-year Follow-up.

    Schwartz-Lifshitz, Maya / Bloch Priel, Stav / Matalon, Noam / Hochberg, Yehonathan / Basel, Dana / Gothelf, Doron

    The Israel Medical Association journal : IMAJ

    2024  Volume 26, Issue 1, Page(s) 8–11

    Abstract: Background: The coronavirus disease 2019 (COVID-19) pandemic caused significant global turmoil, including changes in social and societal conduct such as lockdowns, social isolation, and extensive regulations. These changes can be major sources of stress. ...

    Abstract Background: The coronavirus disease 2019 (COVID-19) pandemic caused significant global turmoil, including changes in social and societal conduct such as lockdowns, social isolation, and extensive regulations. These changes can be major sources of stress. The first wave of the pandemic (April-May 2020) was a time of global uncertainty. We evaluated symptom severity among 29 Israeli children and adolescents with obsessive-compulsive disorder (OCD). Our previous study found that most of these participants did not experience an exacerbation of symptoms.
    Objectives: To re-evaluate the OCD symptoms of 18 participants from the original group of 29 children and adolescents during three time points: before the pandemic, during the first wave, and 2 years later.
    Methods: Obsessive-compulsive symptoms (OCS) were assessed using the Clinical Global Impression Scale (CGI), a functional questionnaire, and the Obsessive-Compulsive Inventory-child version (OCI-CV).
    Results: OCS in patients did not change significantly during the three time points. Participants reported minimal changes in their general functioning 2 years after the outbreak of COVID-19 and showed minimal change in OCI-CV scale scores.
    Conclusions: Our results indicated clinical stability of OCD symptoms among most of the participants.
    MeSH term(s) Humans ; Adolescent ; COVID-19/epidemiology ; Pandemics ; Follow-Up Studies ; Communicable Disease Control ; Obsessive-Compulsive Disorder/diagnosis ; Obsessive-Compulsive Disorder/epidemiology
    Language English
    Publishing date 2024-02-28
    Publishing country Israel
    Document type Journal Article
    ZDB-ID 2008291-5
    ISSN 1565-1088 ; 0021-2180
    ISSN 1565-1088 ; 0021-2180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Post-traumatic growth correlates among parents of children with chronic illnesses: A systematic review and meta-analysis.

    Negri-Schwartz, Ofir / Lavidor, Michal / Shilton, Tal / Gothelf, Doron / Hasson-Ohayon, Ilanit

    Clinical psychology review

    2024  Volume 109, Page(s) 102409

    Abstract: Parenting a child with a chronic illness presents a complex journey marked by various challenges, along with possible personal growth following these challenges. In this systematic review we present three meta-analyses, in order to examine the ... ...

    Abstract Parenting a child with a chronic illness presents a complex journey marked by various challenges, along with possible personal growth following these challenges. In this systematic review we present three meta-analyses, in order to examine the associations of post-traumatic growth (PTG) among parents of children with diverse chronic illnesses, and psychological distress, social support, and resilience. Analyzing 34 studies encompassing a total of 5328 parents, the results reveal several key findings. First, PTG was found to be prevalent among the parents. Second, there was no significant correlation between PTG and psychological distress, suggesting that these two processes may exist independently. Third, a positive correlation was observed between PTG and both social support and resilience-related factors, underscoring the role of these factors in fostering growth among parents of children with chronic illnesses. Additionally, illness type emerged as a moderator, affecting the strength of the above-mentioned correlations with PTG. Specifically, in the case of psychiatric illnesses, correlations of PTG with social support and resilience were stronger than in the context of other illnesses. Overall, this review emphasizes the significance of recognizing and addressing PTG correlates among parents of children with chronic illnesses, offering insights for clinical practice.
    MeSH term(s) Child ; Humans ; Posttraumatic Growth, Psychological ; Adaptation, Psychological ; Parents/psychology ; Resilience, Psychological ; Stress Disorders, Post-Traumatic/psychology ; Chronic Disease
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 604577-7
    ISSN 1873-7811 ; 0272-7358
    ISSN (online) 1873-7811
    ISSN 0272-7358
    DOI 10.1016/j.cpr.2024.102409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Capgras syndrome in children and adolescents: A systematic review.

    Walfisch, Ron / Danieli, Polina Perlman / Mosheva, Mariela / Hochberg, Yehonathan / Shilton, Tal / Gothelf, Doron

    General hospital psychiatry

    2024  Volume 89, Page(s) 32–40

    Abstract: Objectives: To improve understanding of Capgras syndrome (CS) in the pediatric population, this study investigates its clinical features and discerns similarities and differences compared to CS in adults.: Methods: We conducted a descriptive ... ...

    Abstract Objectives: To improve understanding of Capgras syndrome (CS) in the pediatric population, this study investigates its clinical features and discerns similarities and differences compared to CS in adults.
    Methods: We conducted a descriptive systematic review of case reports following PRISMA guidelines, including cases of pediatric patients with CS. Patient demographics, medical and psychiatric history, imposter identity, underlying diagnosis, clinical manifestation, treatments, and outcomes were extracted and analyzed.
    Results: We included 37 articles comprising 38 cases. The median age of patients was 15, with 23 (60.5%) being male. The most prevalent underlying diagnoses were schizophrenia spectrum and other psychotic disorders (47.3%). Imposter identity involved parents in 32 cases (84.2%). Associated symptoms included persecutory delusions (63.1%), auditory hallucinations (42.1%), aggression (31.5%), and depression (21.0%).
    Conclusion: There is a significant gap in our understanding of CS, particularly in pediatric patients. This is the first systematic review of CS in pediatric patients, encompassing all cases found in English literature since 1923.
    Language English
    Publishing date 2024-05-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392299-6
    ISSN 1873-7714 ; 0163-8343
    ISSN (online) 1873-7714
    ISSN 0163-8343
    DOI 10.1016/j.genhosppsych.2024.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Measuring prodromal symptoms in youth with developmental disabilities: a lesson from 22q11 deletion syndrome.

    Gothelf, Doron

    Journal of the American Academy of Child and Adolescent Psychiatry

    2014  Volume 53, Issue 9, Page(s) 945–947

    MeSH term(s) 22q11 Deletion Syndrome/physiopathology ; Female ; Humans ; Male ; Psychiatric Status Rating Scales ; Psychotic Disorders/diagnosis
    Language English
    Publishing date 2014-09
    Publishing country United States
    Document type Comment ; Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 392535-3
    ISSN 1527-5418 ; 0890-8567
    ISSN (online) 1527-5418
    ISSN 0890-8567
    DOI 10.1016/j.jaac.2014.06.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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