Article ; Online: A prospective randomized study to evaluate the efficacy of pressure support ventilation with and without positive end expiratory pressure for preoxygenation in adult patients.
2023 Volume 13, Issue 4, Page(s) 187–191
Abstract: A primary concern for anesthesiologists is the maintenance of oxygenation during general anesthesia. Extending the safe apnea time, which is the time from the onset of apnea until the oxygen saturation concentration reaches 90% or less, increases the ... ...
Abstract | A primary concern for anesthesiologists is the maintenance of oxygenation during general anesthesia. Extending the safe apnea time, which is the time from the onset of apnea until the oxygen saturation concentration reaches 90% or less, increases the margin of safety with tracheal intubation. Preoxygenation before anesthetic induction has been a widely accepted manoeuver to increase oxygen reserves and hence delay the onset of arterial desaturation during apnea. This study aimed to evaluate the efficacy of pressure support ventilation with/without positive end-expiratory pressure (PEEP) for preoxygenation in adult patients. A total of 132 patients, aged 20 to 50 years, scheduled for elective surgery under general anesthesia, requiring endotracheal intubation, were included and randomly divided into three groups (n = 44 per group): spontaneous ventilation (SV), pressure support ventilation without PEEP (PS), and pressure support ventilation with PEEP (PEEP) groups. In the SV group, the patients breathed spontaneously without any support using a face mask; in the PS group, the patients breathed spontaneously with the inspiratory pressure support of 12 cm H |
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MeSH term(s) | Humans ; Adult ; Apnea/therapy ; Prospective Studies ; Positive-Pressure Respiration ; Anesthesia, General ; Oxygen |
Chemical Substances | Oxygen (S88TT14065) |
Language | English |
Publishing date | 2023-04-19 |
Publishing country | Australia |
Document type | Randomized Controlled Trial ; Journal Article |
ZDB-ID | 2616230-1 |
ISSN | 2045-9912 ; 2045-9912 |
ISSN (online) | 2045-9912 |
ISSN | 2045-9912 |
DOI | 10.4103/2045-9912.372665 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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