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  1. Article ; Online: A prospective randomized study to evaluate the efficacy of pressure support ventilation with and without positive end expiratory pressure for preoxygenation in adult patients.

    Taxak, Susheela / Gupta, Mohini / Bala, Renu / Govil, Vasudha / Lallar, Anushmita

    Medical gas research

    2023  Volume 13, Issue 4, Page(s) 187–191

    Abstract: A primary concern for anesthesiologists is the maintenance of oxygenation during general anesthesia. Extending the safe apnea time, which is the time from the onset of apnea until the oxygen saturation concentration reaches 90% or less, increases the ... ...

    Abstract A primary concern for anesthesiologists is the maintenance of oxygenation during general anesthesia. Extending the safe apnea time, which is the time from the onset of apnea until the oxygen saturation concentration reaches 90% or less, increases the margin of safety with tracheal intubation. Preoxygenation before anesthetic induction has been a widely accepted manoeuver to increase oxygen reserves and hence delay the onset of arterial desaturation during apnea. This study aimed to evaluate the efficacy of pressure support ventilation with/without positive end-expiratory pressure (PEEP) for preoxygenation in adult patients. A total of 132 patients, aged 20 to 50 years, scheduled for elective surgery under general anesthesia, requiring endotracheal intubation, were included and randomly divided into three groups (n = 44 per group): spontaneous ventilation (SV), pressure support ventilation without PEEP (PS), and pressure support ventilation with PEEP (PEEP) groups. In the SV group, the patients breathed spontaneously without any support using a face mask; in the PS group, the patients breathed spontaneously with the inspiratory pressure support of 12 cm H
    MeSH term(s) Humans ; Adult ; Apnea/therapy ; Prospective Studies ; Positive-Pressure Respiration ; Anesthesia, General ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2023-04-19
    Publishing country Australia
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2616230-1
    ISSN 2045-9912 ; 2045-9912
    ISSN (online) 2045-9912
    ISSN 2045-9912
    DOI 10.4103/2045-9912.372665
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Functional and radiological outcomes of primary ring fixator versus antibiotic nail in open tibial diaphyseal fractures: A prospective study.

    Rohilla, Rajesh / Arora, Sahil / Kundu, Ankush / Singh, Roop / Govil, Vasudha / Khokhar, Arya

    Injury

    2022  Volume 53, Issue 10, Page(s) 3464–3470

    Abstract: Background: Management of open fractures of tibia is still a matter of debate due to high incidence of infections. Traditionally external fixators have been advocated in managing open tibial fractures. Due to limited efficacy of systemic antibiotics, ... ...

    Abstract Background: Management of open fractures of tibia is still a matter of debate due to high incidence of infections. Traditionally external fixators have been advocated in managing open tibial fractures. Due to limited efficacy of systemic antibiotics, recently antibiotic coated intramedullary interlocking nails have been developed for the management of open tibia fractures. Therefore, we conducted this prospective randomized study to compare the functional and radiological outcomes of primary ring fixator versus antibiotic coated nail in open diaphyseal tibial fractures.
    Methods: The study included 32 patients with Gustilo-Anderson type II and type IIIA fractures of tibial diaphysis. Out of them 16 patients were managed with Ring External Fixator (Group I) and 16 were managed with Ossipro
    Conclusion: Ring fixator as well as antibiotic coated tibial interlocking nail achieved comparable rates of union in the present study. Complication rates were similar in both the groups and the functional and radiological outcomes were comparable in both groups. Results of this study indicate that although ring fixation is an established option for management of open tibial fractures, antibiotic-coated intramedullary nail is also a reliable option in open Grade II and grade IIIA injuries.
    Level of evidence: Level II.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bone Nails ; Diaphyses/diagnostic imaging ; Diaphyses/surgery ; Fracture Fixation, Intramedullary/methods ; Fracture Healing ; Fractures, Open/complications ; Fractures, Open/diagnostic imaging ; Fractures, Open/surgery ; Gentamicins ; Humans ; Prospective Studies ; Tibia ; Tibial Fractures/complications ; Tibial Fractures/diagnostic imaging ; Tibial Fractures/surgery ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents ; Gentamicins
    Language English
    Publishing date 2022-08-09
    Publishing country Netherlands
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2022.08.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A Rare Presentation of Thyroid Mass- A case report.

    Sharma, Namarta / Govil, Vasudha / Vashishth, Sumedha / Rashmi / Saini, Aman Kaur / Kad, Nandita

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2022  Volume 75, Issue 2, Page(s) 984–987

    Abstract: Background-Respiratory symptoms are not uncommon in thyroid diseases and can be overlooked and misdiagnosed as acute exacerbation of asthma or COPD. Case report- A 58 years old female presented to emergency department with complaints of fever, shortness ... ...

    Abstract Background-Respiratory symptoms are not uncommon in thyroid diseases and can be overlooked and misdiagnosed as acute exacerbation of asthma or COPD. Case report- A 58 years old female presented to emergency department with complaints of fever, shortness of breath from last 3-4 days for which she intubated in emergency department and shifted to ICU. Next day patient was absolutely fine and extubated and was planned to be shifted out surprisingly the same episode was repeated following which patient was intubated again and was found to be absolutely normal after 3-4 h and extubated again. The same episode was repeated next day as well. Eventually she was diagnosed to have cystic thyroid swelling. Immediate aspiration of the cyst done to relieve the symptoms and total thyroidectomy was done subsequently and patient was cured of the symptoms. Conclusion- Acute airway obstruction can occur in asymptomatic goitre patients. The anaesthetic management is crucial for airway till definitive surgery is done.
    Supplementary information: The online version contains supplementary material available at 10.1007/s12070-022-03179-x.
    Language English
    Publishing date 2022-11-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-022-03179-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Staphylococcus aureus: Screening for Nasal Carriers in a Community Setting with Special Reference to MRSA.

    Sharma, Yukti / Jain, Sanjay / Singh, Harshvardhan / Govil, Vasudha

    Scientifica

    2014  Volume 2014, Page(s) 479048

    Abstract: Introduction. Emergence of MRSA infections among previously healthy persons in community settings (without exposure to health care facilities) has been noted recently. MRSA infections are now classified as health care-associated MRSA (HA-MRSA) and ... ...

    Abstract Introduction. Emergence of MRSA infections among previously healthy persons in community settings (without exposure to health care facilities) has been noted recently. MRSA infections are now classified as health care-associated MRSA (HA-MRSA) and community-associated MRSA (CA-MRSA) infections. Its colonization is an important risk factor for subsequent MRSA infection. Aims and Objectives. The aim was to screen patients and health care workers for staphylococcal carriage, identify risk factors for MRSA colonization, and determine the sensitivity pattern. Materials and Methods. A total of 200 subjects were screened for nasal carriage after obtaining verbal consent. These were both healthy subjects attending various outpatient departments and health care workers. Specimens were collected from the anterior nares using premoistened sterile cotton swabs and inoculated onto blood agar and mannitol salt agar and incubated at 37°C for 24-48 h. Results. Staphylococcus aureus colonisation was found to be 12% (n = 24). MRSA was identified in 5% (n = 10) which represents 41.66% of SA. A total of 10 strains of MRSA were isolated from 200 subjects, giving an overall positivity rate of 5%. Discussion. Staphylococcal colonization was found to be 12% (MRSA 5%). Fluoroquinolone resistance was remarkable whereas all strains were sensitive to vancomycin, teicoplanin, linezolid, quinupristin-dalfopristin.
    Language English
    Publishing date 2014-06-25
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2672321-9
    ISSN 2090-908X
    ISSN 2090-908X
    DOI 10.1155/2014/479048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Conference proceedings: To compare thiopentone sodium and etomidate as induction agents during general anaesthesia in patients undergoing surgery for traumatic brain injury

    Govil, Vasudha / Kumar, Prashant / Singh, Ishwar

    Journal of Neuroanaesthesiology and Critical Care

    2016  Volume 03, Issue 02

    Event/congress 17th Annual Conference of Indian Society of Neuroanaesthesiology and Critical Care, Bengaluru, India, 2016-02-05
    Language English
    Publishing date 2016-04-01
    Publisher Thieme Medical and Scientific Publishers Private Ltd.
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2937287-2
    ISSN 2348-926X ; 2348-0548
    ISSN (online) 2348-926X
    ISSN 2348-0548
    DOI 10.1055/s-0038-1667578
    Database Thieme publisher's database

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