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  1. Article ; Online: [No title information]

    Gräfe, Daniel

    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

    2023  Volume 195, Issue 10, Page(s) 873

    Title translation Kommentar zu „KINDER – MRT-Befunde nach COVID-19-Infektion bei Kindern“.
    Language German
    Publishing date 2023-10-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    ISSN (online) 1438-9010
    ISSN 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    DOI 10.1055/a-2101-9301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Strahlentherapie des Analkarzinoms

    Gräfe, Daniel / Kocher, Martin / Goeser, Tobias

    2020  

    Institution Universitätsklinikum Köln / Klinik und Poliklinik für Radioonkologie, Cyberknife- und Strahlentherapie
    Author's details vorgelegt von Daniel Gräfe ; 1. Gutachter: Professor Dr. med. M. Kocher, 2. Gutachter: Universitätsprofessor Dr. med. T. Goeser ; aus der Klinik und Poliklinik für Radioonkologie, Cyberknife udn Strahlentherapie der Universität zu Köln
    Subject code 610
    Language German
    Size 72 Seiten, Diagramme
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität zu Köln, 2020
    HBZ-ID HT020563760
    Database Catalogue ZB MED Medicine, Health

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    2020 D 591 order for loan Magazin

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  3. Article: Kommentar zu „KINDER – MRT-Befunde nach COVID-19-Infektion bei Kindern“

    Gräfe, Daniel

    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

    2023  Volume 195, Issue 10, Page(s) 873–873

    Language German
    Publishing date 2023-10-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    ISSN (online) 1438-9010
    ISSN 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    DOI 10.1055/a-2101-9301
    Database Thieme publisher's database

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  4. Book ; Thesis: Vergleichende Genexpressionsanalyse zwischen dem nukleären Antigen La und der überlappenden putativen Methyltransferase HSPC133 in einem neuen transgenen Autoimmunmodell

    Gräfe, Daniel

    2008  

    Author's details vorgelegt von Daniel Gräfe
    Language German
    Size 160 Bl., Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dresden, Techn. Univ., Diss., 2008
    HBZ-ID HT015875569
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Kongenitale Lungenfehlbildungen : Diagnostik und Therapie.

    Dohna, M / Hirsch, W F / Dingemann, J / Gräfe, D

    Radiologie (Heidelberg, Germany)

    2024  Volume 64, Issue 5, Page(s) 357–365

    Abstract: Performance: Congenital pulmonary malformations (CPM) are rare and can be associated with high morbidity. Clinical presentation, diagnostic procedures, imaging, and therapy of CPM are discussed.: Achievements: Today, most CPM can be diagnosed ... ...

    Title translation Congenital pulmonary malformations : Diagnosis and treatment.
    Abstract Performance: Congenital pulmonary malformations (CPM) are rare and can be associated with high morbidity. Clinical presentation, diagnostic procedures, imaging, and therapy of CPM are discussed.
    Achievements: Today, most CPM can be diagnosed prenatally by ultrasound. Postnatally, respiratory symptoms up to respiratory failure and recurrent lower respiratory tract infection are typical findings. Due to low diagnostic accuracy of chest x‑ray in CPM, all children with prenatal diagnosis of CPM or postnatally suspected CPM should undergo cross-sectional imaging.
    Practical recommendations: Based on imaging alone, the various subtypes of CPM cannot be definitively differentiated, which is why histological confirmation remains the gold standard. Surgical resection is the standard of care with minimally invasive procedures increasingly being employed. In certain situations, a watch-and-wait approach is possible.
    MeSH term(s) Humans ; Lung/abnormalities ; Lung/diagnostic imaging ; Lung/surgery ; Infant, Newborn ; Respiratory System Abnormalities/diagnosis ; Respiratory System Abnormalities/therapy ; Respiratory System Abnormalities/surgery ; Female ; Male ; Tomography, X-Ray Computed ; Lung Diseases/diagnosis ; Lung Diseases/therapy ; Lung Diseases/congenital ; Lung Diseases/diagnostic imaging ; Ultrasonography, Prenatal
    Language German
    Publishing date 2024-03-28
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-7056
    ISSN (online) 2731-7056
    DOI 10.1007/s00117-024-01291-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Conference proceedings: Auswirkung von Übergewicht im Kindes- und Jugendalter auf den Kniegelenksknorpel: Erste vorläufige Ergebnisse einer prospektiven monozentrischen T2-Mapping-Studie

    Roth, C / Sorge, I / Gräfe, D / Witt, M / Böker, E / Hirsch, F W

    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

    2023  Volume 195, Issue S 02

    Event/congress 60. GPR Jahrestagung, Wien, 2023-09-14
    Language German
    Publishing date 2023-09-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    ISSN (online) 1438-9010
    ISSN 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    DOI 10.1055/s-0043-1771424
    Database Thieme publisher's database

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  7. Article ; Online: Chest magnetic resonance imaging in cystic fibrosis: technique and clinical benefits.

    Gräfe, Daniel / Prenzel, Freerk / Hirsch, Franz Wolfgang

    Pediatric radiology

    2022  Volume 53, Issue 4, Page(s) 640–648

    Abstract: Cystic fibrosis (CF) is one of the most common inherited and life-shortening pulmonary diseases in the Caucasian population. With the widespread introduction of newborn screening and the development of modulator therapy, tremendous advances have been ... ...

    Abstract Cystic fibrosis (CF) is one of the most common inherited and life-shortening pulmonary diseases in the Caucasian population. With the widespread introduction of newborn screening and the development of modulator therapy, tremendous advances have been made in recent years both in diagnosis and therapy. Since paediatric CF patients tend to be younger and have lower morbidity, the type of imaging modality that should be used to monitor the disease is often debated. Computed tomography (CT) is sensitive to many pulmonary pathologies, but radiation exposure limits its use, especially in children and adolescents. Conventional pulmonary magnetic resonance imaging (MRI) is a valid alternative to CT and, in most cases, provides sufficient information to guide treatment. Given the expected widespread availability of sequences with ultra-short echo times, there will be even fewer reasons to perform CT for follow-up of patients with CF. This review aims to provide an overview of the process and results of monitoring CF with MRI, particularly for centres not specialising in the disease.
    MeSH term(s) Adolescent ; Infant, Newborn ; Humans ; Child ; Cystic Fibrosis/diagnostic imaging ; Cystic Fibrosis/pathology ; Lung/pathology ; Magnetic Resonance Imaging/methods ; Tomography, X-Ray Computed/methods ; Neonatal Screening
    Language English
    Publishing date 2022-11-14
    Publishing country Germany
    Document type Review ; Journal Article
    ZDB-ID 124459-0
    ISSN 1432-1998 ; 0301-0449
    ISSN (online) 1432-1998
    ISSN 0301-0449
    DOI 10.1007/s00247-022-05539-9
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  8. Article ; Online: Managing an open nasofrontal encephalocele after birth.

    Apostolou, Nicolas / Gräfe, Daniel / Knüpfer, Matthias / Krause, Matthias

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2022  Volume 39, Issue 2, Page(s) 535–540

    Abstract: Encephaloceles are relatively uncommon in western countries. Most of the reported cases involve occipital encephaloceles. Open frontal encephaloceles comprise a rare entity. Most of them will be detected during early prenatal diagnostic, whereas the ... ...

    Abstract Encephaloceles are relatively uncommon in western countries. Most of the reported cases involve occipital encephaloceles. Open frontal encephaloceles comprise a rare entity. Most of them will be detected during early prenatal diagnostic, whereas the majority of the pregnancies will be terminated after the consent of the parents. Open frontal encephaloceles pose a great challenge to neurosurgeons as well as anesthesiologists, as these infants present with a microcephaly, non-physiological intracranial anatomy, and low birth weight, thus making the infant prone to excessive blood loss, hypothermia, and death. Neonates born with an incomplete cutaneous coverage are exposed to an imminent threat to life due to the risk of meningitis, necessitating surgical repair in the first days of life. We represent a rare case of an open nasofrontal encephalocele managed surgically in the first day of life. Surgery did not influence the neurological outcome of the patient.
    MeSH term(s) Infant ; Infant, Newborn ; Humans ; Encephalocele/surgery ; Neurosurgeons ; Microcephaly
    Language English
    Publishing date 2022-11-10
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-022-05620-6
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  9. Article ; Online: Numb Chin in Sickle Cell Anemia During Pregnancy.

    Wolf, Benjamin / Gräfe, Daniel / Stepan, Holger

    Deutsches Arzteblatt international

    2021  Volume 117, Issue 47, Page(s) 808

    MeSH term(s) Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/therapy ; Chin ; Humans ; Pregnancy ; Syndrome
    Language English
    Publishing date 2021-01-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.2020.0808b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Increased Musculoskeletal Deformities And Decreased Lung Volume In Patients After Ea/Tef Repair - A Real-Time Mri Study.

    Aubert, Ophelia / Lacher, Martin / Mayer, Steffi / Frahm, Jens / Voit, Dirk / Rosolowski, Maciej / Widenmann, Anke / Hirsch, Franz Wolfgang / Gräfe, Daniel

    Annals of surgery

    2024  

    Abstract: Objective: This study aims to assess morphological and functional postoperative changes after open or minimally invasive (MIS) repair of esophageal atresia (EA) compared to healthy controls by thoracic real-time MRI.: Summary background data: ... ...

    Abstract Objective: This study aims to assess morphological and functional postoperative changes after open or minimally invasive (MIS) repair of esophageal atresia (EA) compared to healthy controls by thoracic real-time MRI.
    Summary background data: Musculoskeletal deformities and pulmonary morbidity are common in children after EA repair. The real-time MRI is a novel technique that provides ultrafast, high-quality images during spontaneous breathing, without sedation even in young children.
    Methods: Children aged 3-18 years were prospectively examined with a 3 Tesla MRI. Musculoskeletal deformities, static thoracic cross-sectional areas (CSA) at three different levels and lung volumes, as well as dynamic right-to-left ratio of CSA of hemithoraces and lung volumes during forced breathing were evaluated.
    Results: 72 children (42 open, 8 MIS, 22 controls) were recruited. In the EA group, rib fusions and adhesions (78%, P<0.01) and scoliosis (15%, P=0.32) were found after thoracotomy, but not after MIS. Mean right-to-left ratio of CSA and lung volumes were lower after EA repair compared to controls (P <0.05), indicating impaired thoracic and lung development. The number of thoracotomies was a significant risk factor for smaller thoracic volumes (P<0.05).
    Conclusions: For the first time, morphological changes and thoracic motility after EA repair were visualized by dynamic real-time MRI. Children after EA repair show decreased right-sided thoracic and lung development compared to controls. Open repair leads to significantly more musculoskeletal deformities. This study emphasizes that musculoskeletal morbidity following a thoracotomy in infancy is high.
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000006193
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