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  1. Book ; Thesis: Rolle der Kinin Rezeptoren beim sekundären Hirnschaden nach transienter fokaler zerebraler Ischämie der Maus

    Gröger, Moritz F.

    (Medizin)

    2007  

    Author's details vorgelegt von Moritz F. Gröger
    Series title Medizin
    Keywords Ischämischer cerebraler Anfall ; Kininrezeptor ; Nervenzelle ; Zelltod
    Subject Ganglienzelle ; Neurozyt ; Neuron ; Transitorische ischämische Attacke ; TIA ; Transitorische zerebrale Ischämie ; Transiente zerebrale Ischämie
    Language German
    Size 161 S. : Ill., graph. Darst.
    Edition 1. Aufl.
    Publisher Dr. Hut
    Publishing place München
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Univ., Diss., 2007
    HBZ-ID HT015040547
    ISBN 978-3-89963-499-0 ; 3-89963-499-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2007 A 2072 order for loan Magazin

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  2. Article ; Online: Biologika: Neue Therapieoption bei schwerer chronischer Rhinosinusitis.

    Gröger, Moritz / Haubner, Frank

    MMW Fortschritte der Medizin

    2022  Volume 164, Issue 19, Page(s) 48–50

    Title translation Biologicals: New therapeutical options for patients with nasal polyps.
    MeSH term(s) Humans ; Nasal Polyps/drug therapy ; Biological Products ; Rhinitis/drug therapy ; Sinusitis/drug therapy ; Chronic Disease
    Chemical Substances Biological Products
    Language German
    Publishing date 2022-10-29
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-022-1991-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Dem Heuschnupfen nicht hilflos ausgeliefert.

    Gröger, Moritz

    MMW Fortschritte der Medizin

    2016  Volume 158, Issue 4, Page(s) 52, 54–6

    Title translation When the nose is itchy.
    MeSH term(s) Adult ; Allergens/immunology ; Desensitization, Immunologic ; Female ; Humans ; Immunoglobulin E/blood ; Intradermal Tests ; Nose ; Pruritus/etiology ; Rhinitis, Allergic, Seasonal/diagnosis ; Rhinitis, Allergic, Seasonal/immunology ; Rhinitis, Allergic, Seasonal/therapy
    Chemical Substances Allergens ; Immunoglobulin E (37341-29-0)
    Language German
    Publishing date 2016-03-03
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 1478211-x
    ISSN 1438-3276
    ISSN 1438-3276
    DOI 10.1007/s15006-016-7882-0
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  4. Article ; Online: Diagnostics of allergic rhinitis under dupilumab therapy.

    Huber, Patrick / Gröger, Moritz / Stihl, Clemens / Frankenberger, Hanna / Bertlich, Mattis / Haubner, Frank / Gellrich, Donata

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2024  

    Abstract: Background: Allergic rhinits is a prevalent condition, affecting a substantial proportion of the population. This study investigates the impact of ongoing biologic therapy, specifically with Dupilumab, on allergy diagnostics in patients with allergic ... ...

    Abstract Background: Allergic rhinits is a prevalent condition, affecting a substantial proportion of the population. This study investigates the impact of ongoing biologic therapy, specifically with Dupilumab, on allergy diagnostics in patients with allergic rhinits.
    Methods: Various tests, including the Skin Prick Test, serum IgE levels and Allergy Screening Panels, were examined for their effectiveness in detecting sensitizations during biologic treatment.
    Results: The results indicate a significant decline in total IgE levels following biologic therapy initiation, aligning with previous findings on Dupilumab's inhibitory effects on IL-4 and IL-13. However, the specific IgE to total IgE ratio for major allergens was not significantly reduced. Comparing diagnostic tools, the Skin Prick Test demonstrates an impressive retention rate of sensitizations (98%) during Dupilumab treatment, outperforming the Allergy Screening Panel, which shows a 75% detection rate. Notably, the panel displays limitations in capturing lower sensitization levels.
    Conclusion: In summary, this study underscores that, despite the influence of biologic therapy on certain markers, standard allergy tests remain viable while emphasizing the importance of considering specific IgE levels rather than relying solely on CAP classes. The Skin Prick Test in particular proves to be a reliable tool for identifying sensitizations during Dupilumab treatment. The results offer valuable guidance for the diagnostic management of Allergic rhinits in individuals subjected to Dupilumab treatment.
    Language English
    Publishing date 2024-05-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-024-08700-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Serological Cross-Reactivity of Various Aspergillus spp. with Aspergillus fumigatus: A Diagnostic Blind Spot.

    Bertlich, Mattis / Freytag, Saskia / Huber, Patrick / Dombrowski, Tobias / Oppel, Eva / Gröger, Moritz

    International archives of allergy and immunology

    2024  , Page(s) 1–8

    Abstract: Introduction: Aspergillus fumigatus is the most common airborne allergen of the Aspergillus family. However, allergies to Aspergillus spp. are increasing, and subsequently, allergies to Aspergillus species other than fumigatus are also on the rise. ... ...

    Abstract Introduction: Aspergillus fumigatus is the most common airborne allergen of the Aspergillus family. However, allergies to Aspergillus spp. are increasing, and subsequently, allergies to Aspergillus species other than fumigatus are also on the rise. Commercial diagnostic tools are still limited to Aspergillus fumigatus. Hence, there is a need for improved tests. We decided to investigate the correlation between serological sensitization to A. fumigatus and other Aspergillus species.
    Methods: Hundred and seven patients with positive skin prick tests to A. fumigatus were included in this study. Immunoglobulin E (IgE) concentrations against A. fumigatus, A. terreus, A. niger, A. flavus, and A. versicolor were measured from specimens by fluorescent enzyme-linked immunoassays.
    Results: Patients showed considerably higher IgE concentrations against A. fumigatus (6.00 ± 15.05 kUA/L) than A. versicolor (0.30 ± 1.01 kUA/L), A. niger (0.62 ± 1.59 kUA/L), A. terreus (0.45 ± 1.12 kUA/L), or A. flavus (0.41 ± 0.97 kUA/L). Regression analysis yielded weak positive correlations for all Aspergillus spp., but low r2 values and heteroscedastic distribution indicate an overall poor fit of the calculated models.
    Conclusion: Serological sensitization against A. fumigatus does not correlate with sensitization against other Aspergillus spp. To detect sensitization against these, other diagnostic tools like a skin prick test solution of different Aspergillus spp. are needed.
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1108932-5
    ISSN 1423-0097 ; 1018-2438
    ISSN (online) 1423-0097
    ISSN 1018-2438
    DOI 10.1159/000538082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Neonatal hearing screening - does failure in TEOAE screening matter when the AABR test is passed?

    Gellrich, Donata / Gröger, Moritz / Echternach, Matthias / Eder, Katharina / Huber, Patrick

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2023  Volume 281, Issue 3, Page(s) 1273–1283

    Abstract: Purpose: Newborns who fail the transient evoked otoacoustic emissions (TEOAE) but pass the automatic auditory brainstem response (AABR) in universal newborn hearing screening (UNHS), frequently have no further diagnostic test or follow-up. The present ... ...

    Abstract Purpose: Newborns who fail the transient evoked otoacoustic emissions (TEOAE) but pass the automatic auditory brainstem response (AABR) in universal newborn hearing screening (UNHS), frequently have no further diagnostic test or follow-up. The present study aimed to investigate whether hearing loss might be missed by ignoring neonatal TEOAE failure in the presence of normal AABR.
    Methods: A retrospective analysis was conducted in newborns presenting between 2017 and 2021 to a tertiary referral centre due to failure in the initial UNHS. The main focus was on infants who failed TEOAE tests, but passed AABR screening. The clinical characteristics and audiometric outcomes were analysed and compared with those of other neonates.
    Results: Among 1,095 referred newborns, 253 (23%) failed TEOAE despite passing AABR screening. Of the 253 affected infants, 154 returned for follow-up. At 1-year follow-up, 46 (28%) achieved normal audiometric results. 32 (21%) infants had permanent hearing loss (HL) confirmed by diagnostic ABR, 58 (38%) infants had HL solely due to middle ear effusion (MEE), and for 18 (12%) infants HL was suspected without further differentiation. The majority of permanent HL was mild (78% mild vs. 13% moderate vs. 9% profound). The rate of spontaneous MEE clearance was rather low (29%) leading to early surgical intervention in 36 children. The profile of the risk factors for hearing impairment was similar to that of newborns with failure in both, TEOAE and AABR; however, there was a stronger association between the presence of risk factors and the incidence of HL (relative risk 1.55 vs. 1.06; odds ratio 3.61 vs. 1.80).
    Conclusion: In newborns, the discordance between a "refer" in TEOAE and a "pass" in AABR screening is associated with a substantial prevalence of hearing impairment at follow-up, especially in the presence of risk factors.
    MeSH term(s) Infant ; Child ; Humans ; Infant, Newborn ; Retrospective Studies ; Evoked Potentials, Auditory, Brain Stem/physiology ; Otoacoustic Emissions, Spontaneous ; Hearing Tests/methods ; Neonatal Screening/methods ; Hearing Loss/diagnosis ; Hearing Loss/epidemiology ; Deafness
    Language English
    Publishing date 2023-10-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-023-08250-z
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  7. Article ; Conference proceedings: Value of a concomitant functional endoscopic paranasal sinus surgery in CRSwNP patients with partial response under antibody therapy.

    Stihl, Clemens / Wiebringhaus, Robert / Gröger, Moritz / Haubner, Frank

    Laryngo-Rhino-Otologie

    2023  Volume 102, Issue S 02

    Event/congress 94th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e.V., Bonn, Congress Center Leipzig, 2023-05-17
    Language English
    Publishing date 2023-05-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0043-1767579
    Database Thieme publisher's database

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  8. Article ; Conference proceedings: Stellenwert einer konkomitanten funktionellen endoskopischen Nasennebenhöhlenoperation bei CRSwNP-Patienten mit partiellem Ansprechen unter einer Antikörpertherapie.

    Stihl, Clemens / Wiebringhaus, Robert / Gröger, Moritz / Haubner, Frank

    Laryngo-Rhino-Otologie

    2023  Volume 102, Issue S 02

    Event/congress 94. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn, Congress Center Leipzig, 2023-05-17
    Language German
    Publishing date 2023-05-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0043-1766924
    Database Thieme publisher's database

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  9. Article: Aktuelles zur allergenspezifischen Immuntherapie. Harmonisierung, Therapieallergeneverordnung und die neue SIT-Leitlinie

    Gröger, Moritz

    HNO-Nachrichten

    2016  Volume 46, Issue 1, Page(s) 17

    Language German
    Document type Article
    ZDB-ID 630263-4
    ISSN 0177-1000
    Database Current Contents Medicine

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  10. Article: Fortbildung. Harmonisierung, Therapieallergeneverordnung und neue SIT-Leitlinie. Aktuelles zur allergenspezifischen Immuntherapie

    Gröger, Moritz

    Hautnah : Dermatologie : Dermatologie aus der Praxis

    2016  Volume 32, Issue 2, Page(s) 32

    Language German
    Document type Article
    ZDB-ID 1058402-x
    ISSN 0938-0221 ; 0930-7109
    Database Current Contents Medicine

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