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  1. Article ; Online: A Two-Stage Automatic Color Thresholding Technique.

    Pootheri, Shamna / Ellam, Daniel / Grübl, Thomas / Liu, Yang

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 6

    Abstract: Thresholding is a prerequisite for many computer vision algorithms. By suppressing the background in an image, one can remove unnecessary information and shift one's focus to the object of inspection. We propose a two-stage histogram-based background ... ...

    Abstract Thresholding is a prerequisite for many computer vision algorithms. By suppressing the background in an image, one can remove unnecessary information and shift one's focus to the object of inspection. We propose a two-stage histogram-based background suppression technique based on the chromaticity of the image pixels. The method is unsupervised, fully automated, and does not need any training or ground-truth data. The performance of the proposed method was evaluated using a printed circuit assembly (PCA) board dataset and the University of Waterloo skin cancer dataset. Accurately performing background suppression in PCA boards facilitates the inspection of digital images with small objects of interest, such as text or microcontrollers on a PCA board. The segmentation of skin cancer lesions will help doctors to automate skin cancer detection. The results showed a clear and robust background-foreground separation across various sample images under different camera or lighting conditions, which the naked implementation of existing state-of-the-art thresholding methods could not achieve.
    Language English
    Publishing date 2023-03-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23063361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Prähospitaler Kreislaufstillstand im Lockdown: Auswirkungen der übergreifenden Infektionspräventionsmaßnahmen während der ersten SARS-CoV-2-Welle.

    Grübl, T / Plöger, B / Sassen, M C / Jerrentrup, A / Schieffer, B / Betz, S

    Notfall & rettungsmedizin

    2021  , Page(s) 1–6

    Abstract: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. Consequences of infection prevention measures during such contagion events can cause disadvantages especially for patients in out-of-hospital cardiac arrest ( ... ...

    Title translation Out-of-hospital cardiac arrest during lockdown.
    Abstract Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. Consequences of infection prevention measures during such contagion events can cause disadvantages especially for patients in out-of-hospital cardiac arrest (OHCA).
    Methods: Retrospective analysis of OHCAs in one county from January-May in 2018, 2019 and 2020, with the first appearance of the SARS-CoV‑2 pandemic in 2020 and a high incidence of the influenza virus in 2018.
    Results: A total of 497 OHCAs were investigated (2018
    Discussion: The lockdown during the first wave of SARS-CoV‑2 pandemic does not seem to have affected the outcome of OHCA patients without coronavirus disease 2019 (COVID-19) in the end.
    Language German
    Publishing date 2021-08-24
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 1424737-9
    ISSN 1436-0578 ; 1434-6222
    ISSN (online) 1436-0578
    ISSN 1434-6222
    DOI 10.1007/s10049-021-00932-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5083: Show issues Location:
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  3. Article ; Online: Education of schoolchildren in cardiopulmonary resuscitation - overview of the current literature.

    Schroeder, Daniel C / Finke, Simon-Richard / Grübl, Tobias / Jänig, Christoph W / Böttiger, Bernd W

    Current opinion in critical care

    2023  Volume 29, Issue 6, Page(s) 616–620

    Abstract: Purpose of review: Recognition of cardiac arrest and initiation of cardiopulmonary resuscitation (CPR) can be learned and adequately replicated by schoolchildren. Regular instruction of schoolchildren in CPR is therefore a core element to increase low ... ...

    Abstract Purpose of review: Recognition of cardiac arrest and initiation of cardiopulmonary resuscitation (CPR) can be learned and adequately replicated by schoolchildren. Regular instruction of schoolchildren in CPR is therefore a core element to increase low bystander CPR rates. Thereby, schoolchildren CPR training evolved as own scientific field within the last decade. Aim was to describe current evidence in terms of epidemiology, teaching approaches and political aspects.
    Recent findings: Schoolchildren demonstrate a high motivation to be trained in CPR. Teaching approaches that combine theoretical and practical learning sessions guarantee a sustainable learning effect. Schoolchildren can adequately perform chest compressions and mouth-to-mouth ventilation from the age of 12 years. Use of digital media is a highly promising teaching approach. CPR training conducted by teachers from the own school is effective and guarantees continuous development of CPR skills. Integration of schoolchildren CPR training into school curricula is the foundation for a sustainable increase of lay resuscitation rates in the population. Scientific and political promotion of schoolchildren CPR training is needed to sensitize the population and move bystander CPR in the social focus.
    Summary: While bystander CPR rates are low in Europe comprehensive establishment of schoolchildren CPR training may sustainably increase survival after cardiac arrest.
    MeSH term(s) Humans ; Child ; Cardiopulmonary Resuscitation ; Internet ; Out-of-Hospital Cardiac Arrest/therapy ; Schools ; Europe
    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000001111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Atemwegsmanagement im Notfall.

    Feth, Maximilian / Fritz, Stephanie / Grübl, Tobias / Gliwitzky, Bernhard / Düsterwald, Stephan / Bathe, Janina / Bernhard, Michael / Hossfeld, Björn

    Deutsche medizinische Wochenschrift (1946)

    2024  Volume 149, Issue 8, Page(s) 458–469

    Abstract: Emergency airway management is a rare but essential emergency medical intervention directly impacting morbidity and mortality of emergency patients. The success of airway management depends on various factors such as patient anatomy, environmental ... ...

    Title translation Airwaymangement in Emergencies.
    Abstract Emergency airway management is a rare but essential emergency medical intervention directly impacting morbidity and mortality of emergency patients. The success of airway management depends on various factors such as patient anatomy, environmental aspects and the provider performing the procedure. Therefore, the use of a clearly structured algorithm for anticipating the difficult airway in emergency situations is strongly recommended. Our article explains different ways of securing the airway as part of a structured algorithm as well as pitfalls and helpful tips.
    MeSH term(s) Humans ; Emergencies ; Airway Management/methods ; Algorithms ; Intubation, Intratracheal
    Language German
    Publishing date 2024-04-02
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/a-2220-1411
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    In stock of ZB MED Cologne/Königswinter

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  5. Article: Patients at Risk for Transfusion-A Six-Year Multicentre Analysis of More Than 320,000 Helicopter Emergency Medical Service Missions.

    Jänig, Christoph / Willms, Chadlia / Schwietring, Jens / Güsgen, Christoph / Willms, Arnulf / Didion, Nicole / Gruebl, Tobias / Bieler, Dan / Schmidbauer, Willi

    Journal of clinical medicine

    2023  Volume 12, Issue 23

    Abstract: Background: In Europe, ambulances are increasingly being equipped with blood products for prehospital use. Available evidence on the early administration of blood products comes from military medicine and the Anglo-American medical literature; the ... ...

    Abstract Background: In Europe, ambulances are increasingly being equipped with blood products for prehospital use. Available evidence on the early administration of blood products comes from military medicine and the Anglo-American medical literature; the evidence cannot be easily transferred to European countries.
    Objectives: This study assesses the incidence of patients with massive haemorrhage after trauma and the potential need for prehospital blood transfusions.
    Methods: Data reported by 37 German air rescue stations between 2015 and 2020 were retrospectively analysed to predict the need for massive transfusion.
    Results: A total of 320,347 helicopter emergency medical service (HEMS) missions were performed and involved 2982 patients with potential need for massive transfusion after trauma (approximately 13 transfusions per helicopter per year). Men were most affected (73%). The median age of patients was 38 years. Traffic accidents accounted for 59% of the cases. Most patients sustained multiple injuries including traumatic brain injuries (62%), as well as thoracic (54%), abdominal (39%), and extremity injuries (41%). The median "rSIG" (reversed shock index multiplied with the Glasgow Coma Scale) decreased from 4.31 to 3.78.
    Conclusions: Although the incidence of haemorrhagic trauma patients is low, the prehospital administration of blood products might be useful as a potentially life-saving bridging treatment until hospital admission.
    Language English
    Publishing date 2023-11-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12237310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Atemwegsmanagement im Notfall

    Feth, Maximilian / Fritz, Stephanie / Grübl, Tobias / Gliwitzky, Bernhard / Düsterwald, Stephan / Bathe, Janina / Bernhard, Michael / Hossfeld, Björn

    DMW - Deutsche Medizinische Wochenschrift

    2024  Volume 149, Issue 08, Page(s) 458–469

    Keywords Atemwegsmanagement ; chirurgischer Atemweg ; Teamarbeit ; Supraglottische Atemwegshilfen ; Endotracheale Intubation ; Notfallmedizin ; Airwaymanagement ; surgical airway ; team approach ; supraglottic airway device ; endotracheal intubation ; emergency medicine ; rapid sequence induction
    Language German
    Publishing date 2024-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/a-2220-1411
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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Point-of-care testing in out-of-hospital cardiac arrest: a retrospective analysis of relevance and consequences.

    Gruebl, Tobias / Ploeger, B / Wranze-Bielefeld, E / Mueller, M / Schmidbauer, W / Kill, C / Betz, S

    Scandinavian journal of trauma, resuscitation and emergency medicine

    2021  Volume 29, Issue 1, Page(s) 128

    Abstract: Background: Metabolic and electrolyte imbalances are some of the reversible causes of cardiac arrest and can be diagnosed even in the pre-hospital setting with a mobile analyser for point-of-care testing (POCT).: Methods: We conducted a retrospective ...

    Abstract Background: Metabolic and electrolyte imbalances are some of the reversible causes of cardiac arrest and can be diagnosed even in the pre-hospital setting with a mobile analyser for point-of-care testing (POCT).
    Methods: We conducted a retrospective observational study, which included analysing all pre-hospital resuscitations in the study region between October 2015 and December 2016. A mobile POCT analyser (Alere epoc®) was available at the scene of each resuscitation. We analysed the frequency of use of POCT, the incidence of pathological findings, the specific interventions based on POCT as well as every patient's eventual outcome.
    Results: N = 263 pre-hospital resuscitations were included and in n = 98 of them, the POCT analyser was used. Of these measurements, 64% were performed using venous blood and 36% using arterial blood. The results of POCT showed that 63% of tested patients had severe metabolic acidosis (pH < 7.2 + BE <  - 5 mmol/l). Of these patients, 82% received buffering treatment with sodium bicarbonate. Potassium levels were markedly divergent normal (> 6.0 mmol/l/ < 2.5 mmol/l) in 17% of tested patients and 14% of them received a potassium infusion. On average, the pre-hospital treatment time between arrival of the first emergency medical responders and the beginning of transport was 54 (± 20) min without POCT and 60 (± 17) min with POCT (p = 0.07). Overall, 21% of patients survived to hospital discharge (POCT 30% vs no POCT 16%, p = 0.01, Φ = 0.16).
    Conclusions: Using a POCT analyser in pre-hospital resuscitation allows rapid detection of pathological acid-base imbalances and potassium concentrations and often leads to specific interventions on scene and could improve the probability of survival.
    MeSH term(s) Cardiopulmonary Resuscitation ; Emergency Service, Hospital ; Humans ; Out-of-Hospital Cardiac Arrest/diagnosis ; Out-of-Hospital Cardiac Arrest/therapy ; Point-of-Care Testing ; Retrospective Studies
    Language English
    Publishing date 2021-08-30
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 2455990-8
    ISSN 1757-7241 ; 1757-7241
    ISSN (online) 1757-7241
    ISSN 1757-7241
    DOI 10.1186/s13049-021-00943-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Thesis: Analysis of the PAT1a binding motif in APP/APLPs and identification of novel PAT1a binding partners affecting APP endocytosis and processing

    Grübl, Tomas

    2007  

    Author's details Tomas Grübl
    Language English
    Size 144 S., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Heidelberg, 2007
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Article: Prähospitaler Kreislaufstillstand unter einem seltenen Umstand

    Grübl, Tobias / Günnewig, Sebastian / Schulte, Holger / Weller, Norbert / Schmidbauer, Willi / Jänig, Christoph Walter / Müller, Gunnar

    NOTARZT

    2022  Volume 39, Issue 03, Page(s) 145–149

    Abstract: Es wird der Fall eines jungen Patienten mit Kreislaufstillstand nach suizidaler Inkorporation von Natriumnitrat beschrieben. Während der Reanimation sind reversible Ursachen zu suchen und schnell zu therapieren. Intoxikationen sind dabei oft nur schwer ... ...

    Abstract Es wird der Fall eines jungen Patienten mit Kreislaufstillstand nach suizidaler Inkorporation von Natriumnitrat beschrieben. Während der Reanimation sind reversible Ursachen zu suchen und schnell zu therapieren. Intoxikationen sind dabei oft nur schwer detektierbar. Nitroverbindungen führen zur Bildung von Methämoglobin und so zur Hypoxie. Anhand mobiler Laborgeräte kann dies bereits prähospital diagnostiziert werden. Therapeutisch ist zunächst ein symptomatisches Vorgehen mit Oxygenierung und Kreislaufunterstützung sowie ggf. erweiterten Maßnahmen angezeigt. Auch für seltene Intoxikationen sollten spezifische Antidota zumindest zentral vorgehalten werden. Notfallmediziner müssen die Zugriffs- und alternative Behandlungsmöglichkeiten bis zu deren Verfügbarkeit kennen. Im Falle eines Kreislaufstillstands können Systeme zur extrakorporalen Kreislaufunterstützung diesen Zeitraum überbrücken.
    Keywords Intoxikation ; Nitrit ; Antidot ; Reanimation ; H´s und HITS ; poisons ; nitrite ; antidotes ; resuscitation ; H´s and T´s
    Language German
    Publishing date 2022-09-05
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2039417-2
    ISSN 1438-8693 ; 0177-2309
    ISSN (online) 1438-8693
    ISSN 0177-2309
    DOI 10.1055/a-1903-1016
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  10. Article: Atemwegsmanagement im Notfall

    Feth, Maximilian / Fritz, Stephanie / Grübl, Tobias / Gliwitzky, Bernhard / Düsterwald, Stephan / Bathe, Janina / Bernhard, Michael / Hossfeld, Björn

    NOTARZT

    2022  Volume 38, Issue 05, Page(s) 269–280

    Keywords Atemwegsmanagement ; chirurgischer Atemweg ; Teamarbeit ; Supraglottische Atemwegshilfen ; Endotracheale Intubation ; Notfallmedizin ; Airwaymanagement ; surgical airway ; team approach ; supraglottic airway device ; endotracheal intubation ; emergency medicine ; rapid sequence induction
    Language German
    Publishing date 2022-10-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2039417-2
    ISSN 1438-8693 ; 0177-2309
    ISSN (online) 1438-8693
    ISSN 0177-2309
    DOI 10.1055/a-1662-9630
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