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  1. Book: Referenz Allgemein- und Viszeralchirurgie: Pankreas

    Brunner, Maximilian / Grützmann, Robert

    (Referenz)

    2022  

    Title variant Pankreas
    Author's details Herausgegeben von Robert Grützmann. Unter Mitarbeit von Maximilian Brunner [und weiteren]
    Series title Referenz
    Keywords 123 ; Pankreaschirurgie;Bauchspeicheldrüse;Bauchspeicheldrüsenkrebs;Bauchspeicheldrüsenoperation;Pankreatitis;Pankreaskarzinom;Pankreasresektion;Bauchspeicheldrüsenentzündung;Bauchspeicheldrüsenchirurgie ; 310 ; Bauchspeicheldrüsenchirurgie
    Language German
    Size 533 Seiten, 340 Illustrationen, 27 cm x 19.5 cm, 1494 g
    Edition 1. Auflage
    Publisher Thieme
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    Note Zugang zu Online-Ausgabe über Code
    HBZ-ID HT021203243
    ISBN 978-3-13-242458-6 ; 3-13-242458-7 ; 9783132424609 ; 9783132424593 ; 3132424609 ; 3132424595
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online ; E-Book: Chirurgie des Kolonkarzinoms

    Benz, Stefan / Grützmann, Robert / Stinner, Benno

    2021  

    Author's details Stefan Benz, Robert Grützmann, Benno Stinner (Hrsg.)
    Keywords Electronic books
    Language German
    Size 1 Online-Ressource (XV, 513 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020908988
    ISBN 978-3-662-60453-3 ; 9783662604526 ; 3-662-60453-1 ; 3662604523
    DOI 10.1007/978-3-662-60453-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Cancer gene profiling

    Grützmann, Robert / Pilarsky, Christian

    methods and protocols

    (Methods in molecular biology ; 1381 ; Springer protocols ; Biomedicine)

    2016  

    Author's details edited by Robert Grützmann, Department of Surgery, Universitätsklinikum Erlangen, Erlangen, Germany ; Christian Pilarsky, Department of Surgery, TU-Dresden, Dresden, Germany
    Series title Methods in molecular biology ; 1381
    Springer protocols
    Biomedicine
    Collection
    Keywords Neoplasms / genetics ; Gene Expression Profiling / methods ; Microarray Analysis / methods
    Language English
    Size x, 256 Seiten, Illustrationen, Diagramme
    Edition Second edition
    Publisher Humana Press
    Publishing place New York
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT018946242
    ISBN 978-1-4939-3203-0 ; 978-1-4939-3204-7 ; 1-4939-3203-9 ; 1-4939-3204-7
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Cancer gene profiling

    Grützmann, Robert / Pilarsky, Christian

    methods and protocols

    (Methods in molecular biology ; 576 ; Springer protocols)

    2010  

    Author's details ed. by Robert Grützmann and Christian Pilarsky
    Series title Methods in molecular biology ; 576
    Springer protocols
    Collection
    Keywords Neoplasms / genetics ; Gene Expression Profiling / methods ; Microarray Analysis / methods
    Language English
    Size XI, 450 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT015985531
    ISBN 978-1-934115-76-3 ; 9781597455459 ; 1-934115-76-2 ; 1597455458
    Database Catalogue ZB MED Medicine, Health

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  5. Article: Screening for pancreatic cancer in individuals with genetic susceptibility.

    Grützmann, Robert / Brunner, Maximilian

    Hepatobiliary surgery and nutrition

    2023  Volume 12, Issue 3, Page(s) 421–423

    Language English
    Publishing date 2023-05-08
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-23-176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Thesis: Untersuchungen an der Schnittstelle zwischen Chirurgie und Immunologie mit besonderem Schwerpunkt auf der Rolle der Sphingosine-1-phosphat-Rezeptoren in der Immunhomöostase

    Schulze, Tobias / Grützmann, Robert / Kalff, Jörg C. / Heidecke, Claus-Dieter

    2018  

    Institution Universität Greifswald
    Author's details vorgelegt von Tobias Schulze ; 1. Gutachter: Prof. Dr. med. Robert Grützmann, Universitätsklinikum Erlangen, 2. Gutachter: Prof. Dr. med. Jörg C. Kalff, Universitätsklinikum Bonn, 3. Gutachter: Prof. Dr. med. Claus-Dieter Heidecke, Universitätsmedizin Greifswald
    Language German ; English
    Size 1 Band (verschiedene Seitenzählungen), Illustrationen, Diagramme
    Publishing place Greifswald
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Habilitationsschrift, Universitätsmedizin der Universität Greifswald, 2019
    Note Text deutsch, Anhang englisch ; Literaturverzeichnis: Blatt 33-39
    HBZ-ID HT020398166
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Mindestmengen aus der Sicht des universitären Versorgers.

    Krautz, Christian / Grützmann, Robert

    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen

    2022  Volume 93, Issue 4, Page(s) 349–355

    Abstract: The association between patient volume and treatment quality has been sufficiently proven for certain surgical interventions (e.g., resections of the esophagus and pancreas). International experience shows that centralization of patient care in these ... ...

    Title translation Minimum case volumes from the perspective of university providers.
    Abstract The association between patient volume and treatment quality has been sufficiently proven for certain surgical interventions (e.g., resections of the esophagus and pancreas). International experience shows that centralization of patient care in these fields leads to an improvement in outcome quality. If properly enforced, minimum caseload requirements can induce centralization effects in the hospital market. Overcapacities in the German hospital market and high nationwide in-hospital mortality rates (e.g., nationwide postoperative hospital mortality after esophageal and pancreatic resections) justify the current changes in the minimum caseload requirement regulation. Nevertheless, still open questions on volume-outcome relationships (e.g., additive volume effects of associated organ systems) have yet to be answered by scientific studies. In addition, the special role of university medical centers in the German healthcare system needs to be considered in the minimum caseload requirement regulation in order not to jeopardize the importance of university clinics in science, education and patient care through self-regulatory processes in the hospital market induced by minimum caseload requirements.
    MeSH term(s) Delivery of Health Care ; Esophagus ; Hospital Mortality ; Humans ; Pancreatectomy ; Universities
    Language German
    Publishing date 2022-03-07
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1521-0
    ISSN 1433-0385 ; 0009-4722
    ISSN (online) 1433-0385
    ISSN 0009-4722
    DOI 10.1007/s00104-022-01604-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Blood Vessel-Targeted Therapy in Colorectal Cancer: Current Strategies and Future Perspectives.

    Jacobsen, Anne / Siebler, Jürgen / Grützmann, Robert / Stürzl, Michael / Naschberger, Elisabeth

    Cancers

    2024  Volume 16, Issue 5

    Abstract: The vasculature is a key player and regulatory component in the multicellular microenvironment of solid tumors and, consequently, a therapeutic target. In colorectal carcinoma (CRC), antiangiogenic treatment was approved almost 20 years ago, but there ... ...

    Abstract The vasculature is a key player and regulatory component in the multicellular microenvironment of solid tumors and, consequently, a therapeutic target. In colorectal carcinoma (CRC), antiangiogenic treatment was approved almost 20 years ago, but there are still no valid predictors of response. In addition, treatment resistance has become a problem. Vascular heterogeneity and plasticity due to species-, organ-, and milieu-dependent phenotypic and functional differences of blood vascular cells reduced the hope of being able to apply a standard approach of antiangiogenic therapy to all patients. In addition, the pathological vasculature in CRC is characterized by heterogeneous perfusion, impaired barrier function, immunosuppressive endothelial cell anergy, and metabolic competition-induced microenvironmental stress. Only recently, angiocrine proteins have been identified that are specifically released from vascular cells and can regulate tumor initiation and progression in an autocrine and paracrine manner. In this review, we summarize the history and current strategies for applying antiangiogenic treatment and discuss the associated challenges and opportunities, including normalizing the tumor vasculature, modulating milieu-dependent vascular heterogeneity, and targeting functions of angiocrine proteins. These new strategies could open perspectives for future vascular-targeted and patient-tailored therapy selection in CRC.
    Language English
    Publishing date 2024-02-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16050890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online ; Thesis: CRISPR/Cas9 Mediated Knock-Out of KRASG12D Mutated Pancreatic Cancer Cell Lines

    Lentsch, Eva [Verfasser] / Grützmann, Robert [Akademischer Betreuer] / Grützmann, Robert [Gutachter]

    2022  

    Author's details Eva Lentsch ; Gutachter: Robert Grützmann ; Betreuer: Robert Grützmann
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
    Publishing place Erlangen
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  10. Book ; Thesis: Die Wechselwirkung von Cholezystokinin und Glutamatagonisten an Neuronen im Corpus geniculatum laterale und Hippokampus der Ratte

    Grützmann, Robert

    1995  

    Author's details von Robert Grützmann
    Language German
    Size 103 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Humboldt-Univ., Diss., 1996
    Note Mikrofiche-Ausg.: 2 Mikrofiches : 24x
    HBZ-ID HT007388733
    Database Catalogue ZB MED Medicine, Health

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