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  1. Book ; Online ; E-Book: Beauty Secrets

    Grablowitz, Doris

    faszinierende Möglichkeiten der ästhetischen Medizin

    2016  

    Author's details Doris Grablowitz
    Subject code 617.952
    Language German
    Size 1 Online-Ressource (373 Seiten), Illustrationen, 25 cm
    Publisher Urania
    Publishing place Freiburg im Breisgau
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019146813
    ISBN 978-3-451-80998-9 ; 3451613956 ; 9783451613951 ; 3-451-80998-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Long-term Performance and Safety of Princess VOLUME PLUS Lidocaine for Midface Augmentation: The PRIMAvera Clinical Study.

    Rzany, Berthold / Sulovsky, Monika / Sattler, Gerhard / Cecerle, Michael / Grablowitz, Doris

    Aesthetic surgery journal

    2023  Volume 44, Issue 2, Page(s) 203–215

    MeSH term(s) Humans ; Lidocaine/adverse effects ; Dermal Fillers/adverse effects ; Cosmetic Techniques/adverse effects ; Prospective Studies ; Treatment Outcome ; Skin Aging ; Patient Satisfaction ; Hyaluronic Acid/adverse effects
    Chemical Substances Lidocaine (98PI200987) ; Dermal Fillers ; Hyaluronic Acid (9004-61-9)
    Language English
    Publishing date 2023-07-12
    Publishing country England
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1093/asj/sjad230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Long-term effectiveness of a hyaluronic acid soft tissue filler in patients with facial lipoatrophy, morphological asymmetry, or debilitating scars.

    Grablowitz, Doris / Ivezic-Schoenfeld, Zrinka / Federspiel, Ira G / Gehl, Benjamin / Kopera, Daisy / Prinz, Martin

    Journal of cosmetic dermatology

    2020  Volume 19, Issue 10, Page(s) 2536–2541

    Abstract: Background: Soft tissue fillers are typically used for rejuvenating an aging face; they are also employed in the treatment of certain pathologic conditions, including facial lipoatrophy, morphological asymmetry, and debilitating scars.: Aims: The aim ...

    Abstract Background: Soft tissue fillers are typically used for rejuvenating an aging face; they are also employed in the treatment of certain pathologic conditions, including facial lipoatrophy, morphological asymmetry, and debilitating scars.
    Aims: The aim of this clinical study was to evaluate the effectiveness and safety of Princess® Volume (PV) in patients with facial lipoatrophy (FLA), morphological asymmetry (MA), or debilitating scars (DS).
    Patients/methods: This prospective, noncomparative, multicenter clinical study consisted of five visits spread across 36 weeks. Up to 60 adult patients suffering from moderate facial lipoatrophy, facial morphological asymmetry, or debilitating scars on the face were to be included. All patients were treated with an HA filler (PV).
    Results: At Week 4, the treatment success rate in the SP was 98% (95% CI [90.4%, 100%]), as assessed by both the investigators and the patients. According to the independent reviewer, the success rate was 93% (95% CI [82.7%, 98.0%]). At Week 24, the effect was maintained in most patients, with success rates of 80% as evaluated by the investigator and 79% by the patient (95% CI [67.6%, 89.8%] and [65.6%, 88.4%], respectively). At Week 36, success rates dropped to 61% as assessed by the investigator and 59% by the patient (95% CI [46.8%, 73.5%] and [45.0%, 71.9%], respectively).
    Conclusions: The clinical study has proven that Princess
    MeSH term(s) Adult ; Cicatrix/etiology ; Cosmetic Techniques ; Face ; Humans ; Hyaluronic Acid ; Prospective Studies
    Chemical Substances Hyaluronic Acid (9004-61-9)
    Language English
    Publishing date 2020-06-22
    Publishing country England
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.13454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Safety And Efficacy Of Princess

    Grablowitz, Doris / Sulovsky, Monika / Höller, Sonja / Ivezic-Schoenfeld, Zrinka / Chang-Rodriguez, Souyet / Prinz, Martin

    Clinical, cosmetic and investigational dermatology

    2019  Volume 12, Page(s) 857–864

    Abstract: Purpose: Nasolabial folds (NLFs) are one of the most noticeable signs of facial aging. NLFs negatively affect self-confidence and social acceptance often leading to a person's desire to improve their appearance using dermal fillers. The hyaluronic acid ... ...

    Abstract Purpose: Nasolabial folds (NLFs) are one of the most noticeable signs of facial aging. NLFs negatively affect self-confidence and social acceptance often leading to a person's desire to improve their appearance using dermal fillers. The hyaluronic acid injectable gel implant Princess
    Methods: Adult women and men with moderate to severe NLFs received one injection of PFL to both NLFs. After 2 weeks, a touch-up treatment could be performed, if deemed necessary by the investigator. The change in NLF severity was assessed using the Nasolabial Fold Severity Rating Scale (NFL-SRS) developed by Croma-Pharma and the Global Aesthetic Improvement Scale (GAIS).
    Results: Out of 60 analyzed subjects, 59 (98.3%) had improved their NLF severity by at least 1 grade on the NFL-SRS at week 4, 58 subjects (96.7%) at weeks 24 and 36. All subjects showed aesthetic improvement (GAIS), at weeks 4 and 24. The investigator judged the aesthetics as very much improved (score of 1) in 45 (75.0%) at week 4, 48 (80.0%) at week 24, and in 39 of 60 subjects, respectively (65.0%) at week 36. Thirty-six weeks post-initial treatment, 56 of 60 subjects (93.3%) were very satisfied or satisfied with the treatment. Adverse device effects (ADEs) were mild or moderate and resolved at latest 25 days post-onset. The most commonly reported ADEs were injection site hematoma and injection site pain.
    Conclusion: PFL was safe and effective in reducing the severity of NLFs. Most subjects were (very) satisfied with the treatment outcome throughout a 36 weeks investigation period.
    Language English
    Publishing date 2019-11-26
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S211544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A prospective, open label, multicenter, postmarket study evaluating Princess VOLUME Lidocaine for the correction of nasolabial folds.

    Kopera, Daisy / Ivezic-Schoenfeld, Zrinka / Chang-Rodriguez, Souyet / Hoeller, Sonja / Grablowitz, Doris / Bartsch, Katrin / Prinz, Martin

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14310

    Abstract: The aim of this study was to investigate the safety and performance of Princess VOLUME Lidocaine in nasolabial fold correction. In this prospective, open label, multicenter, postmarket study subjects received injections of Princess VOLUME Lidocaine into ... ...

    Abstract The aim of this study was to investigate the safety and performance of Princess VOLUME Lidocaine in nasolabial fold correction. In this prospective, open label, multicenter, postmarket study subjects received injections of Princess VOLUME Lidocaine into both NLF at Baseline (Day 0) and if considered necessary by the investigator, at Week 2 (touch-up treatment). This study was conducted in Austria at the Department of Dermatology and Venereology, Medical University of Graz, at the medical aesthetic center MÄZ WIEN, and at the medical aesthetic center Ordination Dr. Bartsch, Vienna. The 62 mainly female (95.2%) subjects had a median age of 52 years with two fully visible, approximately symmetrical NLFs, each scoring grade 2 or 3 on the nasolabial fold severity rating scale (NLF-SRS) developed by Croma-Pharma. The nasolabial fold severity was assessed by NLF-SRS and Global Aesthetic Improvement Scale (GAIS) 4, 24, and 36 weeks later. Adverse events (AEs) were recorded throughout the investigation. With 95.1% of subjects showing an improvement of at least 1 grade of the NLF-SRS at 24 weeks after the treatment, the primary endpoint was achieved, and clinical performance was demonstrated. Princess VOLUME Lidocaine was well tolerated, with only mild AEs, mainly injection site reactions, reported. Subject satisfaction (≥93.5%) and GAIS scores (≥93.5% improvement) were high. Princess VOLUME Lidocaine was effective in reducing NLFs as shown by an improvement in the severity of NLFs by at least one grade in 95.1% of subjects at Weeks 4 and 24.
    MeSH term(s) Cosmetic Techniques/adverse effects ; Female ; Humans ; Hyaluronic Acid ; Lidocaine/adverse effects ; Middle Aged ; Nasolabial Fold ; Prospective Studies ; Skin Aging ; Treatment Outcome
    Chemical Substances Hyaluronic Acid (9004-61-9) ; Lidocaine (98PI200987)
    Language English
    Publishing date 2020-10-05
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Treatment of facial lipoatrophy, morphological asymmetry, or debilitating scars with the hyaluronic acid dermal filler Princess

    Kopera, Daisy / Ivezic-Schoenfeld, Zrinka / Federspiel, Ira G / Grablowitz, Doris / Gehl, Benjamin / Prinz, Martin

    Clinical, cosmetic and investigational dermatology

    2018  Volume 11, Page(s) 621–628

    Abstract: Purpose: The aim of this study was to evaluate the effectiveness and safety of hyaluronic acid (HA) dermal filler when used in the face for medical reconstructive purposes.: Patients and methods: Adult patients with moderately severe facial ... ...

    Abstract Purpose: The aim of this study was to evaluate the effectiveness and safety of hyaluronic acid (HA) dermal filler when used in the face for medical reconstructive purposes.
    Patients and methods: Adult patients with moderately severe facial lipoatrophy (FLA), morphological asymmetry (MA) of the face, or debilitating scars (DS) on the face were included in a prospective, noncomparative, multicenter, postmarket clinical follow-up study. All patients were treated with an HA filler (Princess
    Results: Fifty-three patients were included in the study (FLA 23, MA 17, and DS 13), and 46 patients completed a 6-month follow-up (FLA 20, MA 15, and DS 11). At Week 4 (primary endpoint), the overall treatment success rate was 100% (FLA), 100% (MA), and 94% (DS), based on assessments made by the investigator, patients, and the independent reviewer, respectively. In most patients (~95%), the effect was sustained over 6 months. Treatment-related adverse events were reported in five patients (9%) and included injection site hematoma, injection site pain, and headache.
    Conclusion: Dermal filling with HA gel is a viable treatment option for the correction of various deformities of the face resulting from FLA, MA, or DS.
    Language English
    Publishing date 2018-11-27
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S181964
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Repeated botulinum toxin A injections for the treatment of lines in the upper face: a retrospective study of 4,103 treatments in 945 patients.

    Rzany, Berthold / Dill-Müller, Dorothee / Grablowitz, Doris / Heckmann, Marc / Caird, David

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

    2007  Volume 33, Issue 1 Spec No., Page(s) S18–25

    Abstract: Background: Although botulinum toxin type A (BoNT-A) is a common aesthetic intervention, there are few published data on treatment over more than two cycles.: Objective: To evaluate the effectiveness/safety of repeated doses of BoNT-A (Dysport, Ipsen ...

    Abstract Background: Although botulinum toxin type A (BoNT-A) is a common aesthetic intervention, there are few published data on treatment over more than two cycles.
    Objective: To evaluate the effectiveness/safety of repeated doses of BoNT-A (Dysport, Ipsen Ltd., Slough, UK) in the upper face for reduction of wrinkles.
    Methods: Retrospective, cross-sectional patient chart review from 945 patients who had received a minimum of three consecutive, documented treatment cycles.
    Results: The glabella was treated most frequently (93.9%), with the majority (81.5%) of patients receiving treatment in more than one area of the face. BoNT-A treatments were combined with other aesthetic procedures in 57.5% of cases, mostly with fillers (37.1%). There was no evidence of tachyphylaxia: the dose applied, the interval between treatments, and satisfaction with the results remained stable over the course of treatment. Adverse events were those expected with BoNT-A treatment (most common: local bruising and ptosis) and were all mild or moderate in intensity. There was no sign of any cumulative adverse effects: indeed, the adverse-event rate decreased in later treatment cycles.
    Conclusions: Long-term, repeated injections of BoNT-A for corrections of wrinkles in the upper face yield a continuously high level of safety and effectiveness in actual practice.
    MeSH term(s) Adult ; Botulinum Toxins, Type A/administration & dosage ; Cosmetic Techniques ; Eyebrows/anatomy & histology ; Face ; Female ; Humans ; Injections ; Middle Aged ; Neuromuscular Agents/administration & dosage ; Retrospective Studies
    Chemical Substances Neuromuscular Agents ; Botulinum Toxins, Type A (EC 3.4.24.69)
    Language English
    Publishing date 2007-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1227586-4
    ISSN 1524-4725 ; 1076-0512
    ISSN (online) 1524-4725
    ISSN 1076-0512
    DOI 10.1111/j.1524-4725.2006.32327.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Noninferiority of incobotulinumtoxinA, free from complexing proteins, compared with another botulinum toxin type A in the treatment of glabellar frown lines.

    Sattler, Gerhard / Callander, Michael J / Grablowitz, Doris / Walker, Torsten / Bee, Eva K / Rzany, Berthold / Flynn, Timothy Corcoran / Carruthers, Alastair

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

    2010  Volume 36 Suppl 4, Page(s) 2146–2154

    Abstract: Background: Use of botulinum toxin for esthetic purposes has rapidly expanded over the last 20 years. IncobotulinumtoxinA, also known as NT 201, is a new botulinum toxin type A (150 kDa) that is free from complexing proteins.: Objectives: A ... ...

    Abstract Background: Use of botulinum toxin for esthetic purposes has rapidly expanded over the last 20 years. IncobotulinumtoxinA, also known as NT 201, is a new botulinum toxin type A (150 kDa) that is free from complexing proteins.
    Objectives: A prospective, multicenter, randomized, rater- and patient-blind, international Phase III trial to investigate the noninferiority of incobotulinumtoxinA to another botulinum toxin type A, onabotulinumtoxinA, in the treatment of glabellar frown lines.
    Methods: A total of 381 patients were randomized in a 3:1 (incobotulinumtoxinA:onabotulinumtoxinA) ratio to receive 24 U incobotulinumtoxinA of or onabotulinumtoxinA. Efficacy end points included the percentage of responders (patients with an improvement of ≥1 point on a 4-point facial wrinkle scale) at maximum frown at weeks 4 and 12 as assessed by the investigators, and a panel of independent raters based on standardized digital photographs.
    Results: Four weeks after injection, response rates at maximum frown were 96.4% in the incobotulinumtoxinA group and 95.7% in the onabotulinumtoxinA group as assessed by independent raters. Analysis of the data confirmed the noninferiority of incobotulinumtoxinA. Response rates at rest were lower for both products. The rate of adverse events was low.
    Conclusion: IncobotulinumtoxinA is equally as effective as onabotulinumtoxinA in the treatment of glabellar frown lines. Both preparations were well tolerated.
    MeSH term(s) Adult ; Botulinum Toxins, Type A/administration & dosage ; Double-Blind Method ; Forehead ; Humans ; Middle Aged ; Neuromuscular Agents/administration & dosage ; Prospective Studies ; Skin Aging/drug effects ; Young Adult
    Chemical Substances Neuromuscular Agents ; onabotulinumtoxinA (E211KPY694) ; Botulinum Toxins, Type A (EC 3.4.24.69) ; incobotulinumtoxinA (EC 3.4.24.69)
    Language English
    Publishing date 2010-12
    Publishing country United States
    Document type Clinical Trial, Phase III ; Comparative Study ; Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1227586-4
    ISSN 1524-4725 ; 1076-0512
    ISSN (online) 1524-4725
    ISSN 1076-0512
    DOI 10.1111/j.1524-4725.2010.01706.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Liposuction - a surgical procedure in dermatology.

    Rapprich, Stefan / Koller, Josef / Sattler, Gerhard / Wörle, Birgit / Sommer, Boris / Bechara, Falk G / Koenen, Wolfgang / Kunte, Christian / Grablowitz, Doris / Hoffmann, Klaus / Fratila, Alina / Bruning, Guido / Podda, Maurizio / Schuller-Petrovic, Sanja / Karsai, Syrus / Schmeller, Wilfried / Meier-Vollrath, Ilka / Faulhaber, Jörg / Brodersen, Jens /
    Boehler, Kornelia / Löser, Christoph

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2012  Volume 10, Issue 2, Page(s) 111–113

    Abstract: Liposuction is an integral part of the wide range of surgical procedures in dermatology. Dermatologists established tumescent local anesthesia in combination with the use of micro-cannulas; especially dermatologists from Germany and Austria actively ... ...

    Abstract Liposuction is an integral part of the wide range of surgical procedures in dermatology. Dermatologists established tumescent local anesthesia in combination with the use of micro-cannulas; especially dermatologists from Germany and Austria actively designed and developed these new techniques. In this position paper, we discuss the history, various interdisciplinary aspects, the significance, and the treatment indications for this procedure as well as its role within dermatologic training programs and research. For quality reasons, members of the Germany Society of Dermatologic Surgery and the Austrian Society of Dermatologic Surgery discuss several fundamental professional aspects as well as the historical development of liposuction.
    MeSH term(s) Dermatologic Surgical Procedures ; Dermatology/trends ; Humans ; Lipectomy/methods ; Lipectomy/trends ; Reconstructive Surgical Procedures/methods ; Reconstructive Surgical Procedures/trends
    Language English
    Publishing date 2012-02
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/j.1610-0387.2011.07847.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Liposuktion - ein operatives Verfahren in der Dermatologie. Liposuction - a surgical procedure in dermatology

    Rapprich, Stefan / Koller, Josef / Sattler, Gerhard / Wörle, Birgit / Sommer, Boris / Bechara, Falk G. / Koenen, Wolfgang / Kunte, Christian / Grablowitz, Doris / Hoffmann, Klaus / Fratila, Alina / Bruning, Guido / Podda, Maurizio / Schuller-Petrovic, Sanja / Karsai, Syrus / Schmeller, Wilfried / Meier-Vollrath, Ilka / Faulhaber, Jörg / Brodersen, Jens /
    Boehler, Kornelia / Löser, Christoph

    Journal der Deutschen Dermatologischen Gesellschaft

    2012  Volume 10, Issue 2, Page(s) 111

    Language German
    Document type Article
    ZDB-ID 2093479-8
    ISSN 1610-0379
    Database Current Contents Medicine

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