LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 170

Search options

  1. Book ; Thesis: Das Pflichtteilsrecht als Brücke zwischen Privatautonomie und postmortaler Familiensolidarität

    Graf, Nicole

    Analyse von Legitimität und Reformbedürftigkeit ; Grenzen lebzeitiger gemeinwohlorientierter Stifterfreiheit im Pflichtteilsergänzungsrecht

    2009  

    Author's details von Nicole Graf
    Keywords Deutschland ; Pflichtteilsrecht
    Subject code 346.43054 ; 346.4054
    Language German
    Size 359 Bl., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Jena, Univ., Diss., 2009
    HBZ-ID HT015916334
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 E 1370 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Paediatric Orbital Juvenile Xanthogranuloma: A Case Series and Review of the Literature.

    Lee, Ming-Han H / Smith, Ebony J / Hardy, Thomas G / Graf, Nicole / Tumuluri, Krishna

    Ophthalmic plastic and reconstructive surgery

    2024  

    Abstract: Purpose: Juvenile xanthogranuloma (JXG) is a subtype of histiocytosis characterised histologically by foamy non-Langerhan cells with Touton giant cells. It typically manifests as a single self-limiting cutaneous nodule in the paediatric population. ... ...

    Abstract Purpose: Juvenile xanthogranuloma (JXG) is a subtype of histiocytosis characterised histologically by foamy non-Langerhan cells with Touton giant cells. It typically manifests as a single self-limiting cutaneous nodule in the paediatric population. Orbital JXG is extremely rare, and its clinical course and management are not well understood or defined. Herein we present 3 cases of orbital JXG and provide a detailed literature review.
    Methods: Review of 3 cases with orbital JXG and literature review of all published cases.
    Results: Three presented cases demonstrate the heterogeneous clinical course of orbital JXG. Although centred around the use of steroids, there is neither robust evidence nor consensus on its management. The wider JXG literature is currently concentrated around the classification of JXG with respect to histiocytosis, especially the exclusion of extracutaneous JXG as separate diseases. This separation is based on clinical, histopathological, and molecular findings. It is unclear where orbital JXG best fits in this emerging classification of JXG.
    Conclusion: Our review of the cases and literature on orbital JXG show that it may manifest with variable clinical course and its molecular pathogenic mechanism may be different to that of the cutaneous JXG.
    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0000000000002696
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Sideways crab-walking is faster and more efficient than forward walking for a hexapod robot.

    Chen, Yang / Grezmak, John E / Graf, Nicole M / Daltorio, Kathryn A

    Bioinspiration & biomimetics

    2022  Volume 17, Issue 4

    Abstract: Articulated legs enable the selection of robot gaits, including walking in different directions such as forward or sideways. For longer distances, the best gaits might maximize velocity or minimize the cost of transport (COT). While animals often have ... ...

    Abstract Articulated legs enable the selection of robot gaits, including walking in different directions such as forward or sideways. For longer distances, the best gaits might maximize velocity or minimize the cost of transport (COT). While animals often have morphology suited to walking either forward (like insects) or sideways (like crabs), hexapod robots often default to forward walking. In this paper, we compare forward walking with crab-like sideways walking. To do this, a simple gait design method is introduced for determining forward and sideways gaits with equivalent body heights and step heights. Specifically, the frequency and stride lengths are tuned within reasonable constraints to find gaits that represent a robot's performance potential in terms of speed and energy cost. Experiments are performed in both dynamic simulation in Webots and a laboratory environment with our 18 degree-of-freedom hexapod robot, Sebastian. With the common three joint leg design, the results show that sideways walking is overall better (75% greater walking speed and 40% lower COT). The performance of sideways walking was better on both hard floors and granular media (dry play sand). This supports development of future crab-like walking robots for future applications. In future work, this approach may be used to develop nominal gaits without extensive optimization, and to explore whether the advantages of sideways walking persist for other hexapod designs.
    MeSH term(s) Animals ; Brachyura ; Gait ; Insecta ; Robotics/methods ; Walking
    Language English
    Publishing date 2022-05-11
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2235670-8
    ISSN 1748-3190 ; 1748-3182
    ISSN (online) 1748-3190
    ISSN 1748-3182
    DOI 10.1088/1748-3190/ac6847
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Dactyls and inward gripping stance for amphibious crab-like robots on sand.

    Graf, Nicole M / Behr, Alexander M / Daltorio, Kathryn A

    Bioinspiration & biomimetics

    2021  Volume 16, Issue 2

    Abstract: Sandy beaches are areas that challenge robots of all sizes, especially smaller scale robots. Sand can hinder locomotion and waves apply hydrodynamic forces which can displace, reorient, or even invert the robot. Crab-like legs and gaits are well suited ... ...

    Abstract Sandy beaches are areas that challenge robots of all sizes, especially smaller scale robots. Sand can hinder locomotion and waves apply hydrodynamic forces which can displace, reorient, or even invert the robot. Crab-like legs and gaits are well suited for this environment and could be used as inspiration for an improved design of robots operating in this terrain. Tapered, curved feet (similar to crab dactyl shape) paired with a distributed inward gripping method are hypothesized to enable better anchoring in sand to resist hydrodynamic forces. This work demonstrates that crab-like legs can withstand vertical forces that are larger than the body weight (e.g. in submerged sand, the force required to lift the robot can be up to 138% of the robot weight). Such legs help the robot hold its place against hydrodynamic forces imparted by waves (e.g. compared to displacement of 42.7 mm with the original feet, crab-like feet reduced displacement to 1.6 mm in lab wave tests). These feet are compatible with walking on sandy and rocky terrain (tested at three speeds: slow, medium, and fast), albeit at reduced speeds from traditional feet. This work shows potential for future robots to utilize tapered and curved feet to traverse challenging surf zone terrain where biological crabs thrive.
    MeSH term(s) Animals ; Brachyura ; Gait ; Locomotion ; Robotics/methods ; Sand
    Chemical Substances Sand
    Language English
    Publishing date 2021-03-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2235670-8
    ISSN 1748-3190 ; 1748-3182
    ISSN (online) 1748-3190
    ISSN 1748-3182
    DOI 10.1088/1748-3190/abdd94
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Mucomuscular Elastic Flap for Lower Lip Vermilion Reconstruction: Experience in a Series of Cases in Pediatric Patients.

    Giugliano, Carlos / Graf, Stephanie / Graf, Nicole

    The Journal of craniofacial surgery

    2021  Volume 32, Issue 4, Page(s) 1529–1531

    Abstract: Abstract: The mucocutaneous line and the lip vermilion are important structures from an esthetic standpoint but also in relation to the functionality of the mouth. In the literature, several types of flaps have been described for reparation of labial ... ...

    Abstract Abstract: The mucocutaneous line and the lip vermilion are important structures from an esthetic standpoint but also in relation to the functionality of the mouth. In the literature, several types of flaps have been described for reparation of labial defects in adults. In this study, the authors analyze results of surgical reconstruction of the lower lip in the pediatric population using unilateral or bilateral mucomuscular elastic flaps for labial reconstruction. A retrospective analysis of 10 patients operated between 2003 and 2018 at our institution was made. The following demographic and clinical data were collected: age, sex, diagnosis, type of flap, follow-up, results, and complications. The Strasser scale was chosen for assessment of postoperative photographic results. Average age was 8.1 years (range 3-18). The most frequent etiology was arteriovenous malformation seen in 60% of cases. All cases corresponded to a defect of the lower lip. The average percentage of lip compromised was 44% and the largest length of compromise observed was 60% of the lip. Follow-up was on average 2.4 years. Esthetic results according to the Strasser method were as follows: 1 patient presented an excellent esthetic result, 5 good, 4 regular, and 0 poor.Considering the esthetic outcomes and low incidence of complications of the mucomuscular elastic flap, it is an acceptable and recommended technique of choice for lip vermilion reconstruction.
    MeSH term(s) Adolescent ; Adult ; Child ; Child, Preschool ; Esthetics, Dental ; Humans ; Lip/surgery ; Lip Neoplasms/surgery ; Reconstructive Surgical Procedures ; Retrospective Studies ; Surgical Flaps
    Language English
    Publishing date 2021-06-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000007313
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3761: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 175: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Prostatic Artery Embolisation Versus Transurethral Resection of the Prostate for Benign Prostatic Obstruction: 5-year Outcomes of a Randomised, Open-label, Noninferiority Trial.

    Müllhaupt, Gautier / Hechelhammer, Lukas / Graf, Nicole / Mordasini, Livio / Schmid, Hans-Peter / Engeler, Daniel S / Abt, Dominik

    European urology focus

    2024  

    Abstract: Background and objective: Prostatic artery embolisation (PAE) and transurethral resection of the prostate (TURP) are two of the surgical options for treatment of lower urinary tract symptoms/benign prostatic obstruction (LUTS/BPO). Our aim was to ... ...

    Abstract Background and objective: Prostatic artery embolisation (PAE) and transurethral resection of the prostate (TURP) are two of the surgical options for treatment of lower urinary tract symptoms/benign prostatic obstruction (LUTS/BPO). Our aim was to compare the efficacy and safety of PAE and TURP for LUTS/BPO treatment at long-term follow-up.
    Methods: We conducted a randomised, open-label, single-centre trial at a Swiss tertiary care centre. The main outcome was the change in International Prostate Symptom Score (IPSS) after PAE versus TURP. Secondary outcomes included patient-reported outcomes, functional measures, and adverse events assessed at baseline and at 3, 6, 12, 24, and 60 mo. Between-group differences in the change from baseline to 5 yr were tested using two-sided Mann-Whitney and t tests.
    Key findings and limitations: Of the 103 patients with refractory LUTS/BPO who were randomised between 2014 and 2017, 18/48 who underwent PAE and 38/51 who underwent TURP reached the 60-mo follow-up visit. The mean reduction in IPSS from baseline to 5 yr was -7.78 points after PAE and -11.57 points after TURP (difference 3.79 points, 95% confidence interval [CI] -0.66 to 8.24; p = 0.092). TURP was superior for most patient-reported secondary outcomes except for erectile function. At 5 yr, PAE was less effective than TURP regarding objective parameters, such as the improvement in maximum urinary flow rate (3.59 vs 9.30 ml/s, difference -5.71, 95% CI -10.72 to -0.70; p = 0. 027) and reduction in postvoid residual volume (27.81 vs 219.97 ml; difference 192.15, 95% CI 83.79-300.51; p = 0.001).
    Conclusions and clinical implications: The improvement in LUTS/BPO at 5 yr after PAE was inferior to that achieved with TURP. The limitations of PAE should be considered during patient selection and counselling.
    Patient summary: In this study, we show the long-term results of prostate artery embolisation (PAE) in comparison to transurethral resection of the prostate (TURP) for the treatment of benign prostate enlargement causing urinary symptoms. PAE shows good long-term results in properly selected patients, although the improvements are less pronounced than with TURP. This trial is registered on ClinicalTrials.gov as NCT02054013.
    Language English
    Publishing date 2024-03-25
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2024.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Fractional CO

    Wyss, Nina / Graf, Nicole / Hafner, Juerg / Imhof, Laurence

    Dermatologic therapy

    2021  Volume 34, Issue 4, Page(s) e14999

    Abstract: Ablative fractionated carbon dioxide ( ... ...

    Abstract Ablative fractionated carbon dioxide (fCO
    MeSH term(s) Carbon Dioxide ; Cicatrix/etiology ; Cicatrix/pathology ; Cicatrix/surgery ; Humans ; Laser Therapy ; Lasers, Gas ; Retrospective Studies ; Skin Neoplasms/surgery ; Treatment Outcome
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2021-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14999
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5181: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Isolated abdominal kaposiform lymphangiomatosis: a novel presentation of a rare entity.

    Chen, George / Graf, Nicole S / Pang, Tony

    Pathology

    2020  Volume 53, Issue 2, Page(s) 279–282

    MeSH term(s) Abdomen/pathology ; Female ; Hemangioendothelioma/diagnosis ; Hemangioendothelioma/pathology ; Humans ; Kasabach-Merritt Syndrome/diagnosis ; Kasabach-Merritt Syndrome/pathology ; Lymphangioleiomyomatosis/pathology ; Sarcoma, Kaposi/diagnosis ; Sarcoma, Kaposi/pathology ; Young Adult
    Language English
    Publishing date 2020-10-07
    Publishing country England
    Document type Letter
    ZDB-ID 7085-3
    ISSN 1465-3931 ; 0031-3025
    ISSN (online) 1465-3931
    ISSN 0031-3025
    DOI 10.1016/j.pathol.2020.07.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 723: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Aneurysmal Bone Cyst of the Orbit With USP6 Gene Rearrangement.

    Phan, Tracey / Tong, Jessica / Krivanek, Michael / Graf, Nicole / Dexter, Mark / Tumuluri, Krishna

    Ophthalmic plastic and reconstructive surgery

    2022  Volume 39, Issue 3, Page(s) 206–210

    Abstract: Purpose: Aneurysmal bone cyst (ABC) of the orbit is a very rare tumor, occurring mostly in the pediatric population, and can result in sight threatening complications and disfigurement. This review discusses previously reported cases with a focus on ... ...

    Abstract Purpose: Aneurysmal bone cyst (ABC) of the orbit is a very rare tumor, occurring mostly in the pediatric population, and can result in sight threatening complications and disfigurement. This review discusses previously reported cases with a focus on evolving treatment options and molecular genetics.
    Methods: We report the youngest case of an orbital ABC with a confirmed gene fusion: a 17-month-old girl, with confirmed FGFR-UPS6 (Fibroblast Growth Factor Receptor 1-ubiquitin specific peptidase 6/tre-2). A literature search for relevant publications on the topic was performed via Medline and PubMed, with the appropriate data extracted.
    Results: Thirty-two cases of orbital aneurysmal bone cyst were identified in the literature. Presentations are varied and can include pain, proptosis, decreased vision, and extraocular motility disturbance. Typical imaging and histopathology findings are discussed, in particular the usefulness of identifying USP6 gene arrangements. Treatment modalities are reviewed including surgery, embolization, and receptor activator of nuclear factor kappa-B ligand (RANKL) inhibitors. Recurrences can occur, usually within 2 years.
    Conclusions: Orbital ABC is a neoplasm that presents unique diagnostic and treatment challenges. Gene rearrangements can confirm primary ABC and rule out other underlying pathology. Disfigurement and sight threatening complications can occur due to both the disease process and with treatment. Outcomes may be improved with the use of systemic therapy.
    MeSH term(s) Child ; Female ; Humans ; Infant ; Bone Cysts, Aneurysmal/diagnosis ; Bone Cysts, Aneurysmal/genetics ; Bone Cysts, Aneurysmal/pathology ; In Situ Hybridization, Fluorescence ; Orbit/pathology ; Proto-Oncogene Proteins/genetics ; Ubiquitin Thiolesterase/genetics ; Translocation, Genetic
    Chemical Substances Proto-Oncogene Proteins ; Ubiquitin Thiolesterase (EC 3.4.19.12) ; USP6 protein, human (EC 3.4.19.12)
    Language English
    Publishing date 2022-10-20
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0000000000002287
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Kidney biopsy adequacy and complications in children - does technique matter?

    Pettit, Chen / Kanagaratnam, Roshana / Coughlan, Finbarr / Graf, Nicole / Hahn, Deirdre / Durkan, Anne

    European journal of pediatrics

    2022  Volume 181, Issue 7, Page(s) 2677–2684

    Abstract: Kidney biopsy is part of the diagnostic workup of many children with renal disease. Traditionally, a perpendicular approach to the biopsy has been used, but more recently, some proceduralists have favoured a tangential approach. It is not clear if one ... ...

    Abstract Kidney biopsy is part of the diagnostic workup of many children with renal disease. Traditionally, a perpendicular approach to the biopsy has been used, but more recently, some proceduralists have favoured a tangential approach. It is not clear if one technique is superior with regards to tissue adequacy or complication rates. In our centre, interventional radiologists (IR) use general anaesthetic and a tangential approach, whereas paediatric nephrologists (PN) use sedation and a perpendicular approach. We examined consecutive native kidney biopsies performed between January 2008 and December 2017 for adequacy (sufficient tissue for light and electron microscopy and immunofluorescence) and examined the electronic medical records for data regarding technique and complications. IR performed 72 (29%) of the 245 native kidney biopsies, obtaining more total glomeruli (median 39 vs 16, p < 0.001) and more glomeruli per tissue core (median 13 vs 8, p < 0.001) than PN. No differences in specimen adequacy were observed between the two groups (79% IR vs 81% PN, p = 0.75) and a diagnosis could be made in 99% and 94% respectively (p = 0.1). A statistically lower rate of peri-nephric haematoma (28% vs 42%, p = 0.04) was detected in the IR group, but there were no significant differences in other complications. One patient required a blood transfusion (PN) and another required surgical intervention for a perinephric haematoma (IR).
    Conclusion: IR obtained larger samples and number of glomeruli, but the overall adequacy for native kidney biopsies was good using both perpendicular and tangential techniques, with low rates of significant complications.
    What is known: • Kidney biopsy is integral to the diagnostic work-up of many children with kidney disease. • Kidney biopsy is a safe procedure with well-established complications in a minority of children.
    What is new: • Interventional radiologists had higher biopsy yield than paediatric nephrologists, possibly due to the tangential approach. • Biopsy adequacy rates are high using both techniques and provided a diagnosis in over 95% of cases.
    MeSH term(s) Biopsy/adverse effects ; Biopsy/methods ; Child ; Hematoma ; Humans ; Kidney/pathology ; Kidney Diseases/diagnosis ; Kidney Diseases/etiology ; Nephrectomy ; Retrospective Studies
    Language English
    Publishing date 2022-04-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-022-04464-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Um IV Zs.75: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top