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  1. AU="Graff, Nicholas R"
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  1. Article ; Online: Notes from the Field: Increase in Nontoxigenic Corynebacterium diphtheriae - Washington, 2018-2023.

    Xie, Amy G / Yomogida, Kyle / Berry, Isha / Briggs, Nicole L / Esie, Precious / Hamlet, Arran / Paris, Keely / Tromble, Erin / DeBolt, Chas / Graff, Nicholas R / Chow, Eric J

    MMWR. Morbidity and mortality weekly report

    2024  Volume 73, Issue 17, Page(s) 405–407

    MeSH term(s) Humans ; Corynebacterium diphtheriae/isolation & purification ; Diphtheria/epidemiology ; Adolescent ; Washington/epidemiology ; Adult ; Child ; Middle Aged ; Child, Preschool ; Male ; Young Adult ; Female ; Infant ; Aged
    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 412775-4
    ISSN 1545-861X ; 0149-2195
    ISSN (online) 1545-861X
    ISSN 0149-2195
    DOI 10.15585/mmwr.mm7317a4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1827: Show issues Location:
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  2. Article ; Online: Cluster of Nontoxigenic Corynebacterium diphtheriae Infective Endocarditis and Rising Background C. diphtheriae Cases-Seattle, Washington, 2020-2023.

    Karmarkar, Ellora N / Fitzpatrick, Thomas / Himmelfarb, Sarah T / Chow, Eric J / Smith, Hayden Z / Lan, Kristine F / Matsumoto, Jason / Graff, Nicholas R / DeBolt, Chas / Truong, Thao / Bourassa, Lori / Farquhar, Carey / Fang, Ferric C / Kim, H Nina / Pottinger, Paul S

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2024  Volume 78, Issue 5, Page(s) 1214–1221

    Abstract: Background: Nontoxigenic Corynebacterium diphtheriae, often associated with wounds, can rarely cause infective endocarditis (IE). Five patients with C. diphtheriae IE were identified within 12 months at a Seattle-based hospital system. We reviewed prior ...

    Abstract Background: Nontoxigenic Corynebacterium diphtheriae, often associated with wounds, can rarely cause infective endocarditis (IE). Five patients with C. diphtheriae IE were identified within 12 months at a Seattle-based hospital system. We reviewed prior C. diphtheriae-positive cultures to determine if detections had increased over time and evaluated epidemiologic trends.
    Methods: We conducted a formal electronic health record search to identify all patients aged ≥18 years with C. diphtheriae detected in a clinical specimen (ie, wound, blood, sputum) between 1 September 2020 and 1 April 2023. We collected patient demographics, housing status, comorbidities, substance-use history, and level of medical care required at detection. We extracted laboratory data on susceptibilities of C. diphtheriae isolates and on other pathogens detected at the time of C. diphtheriae identification.
    Results: Between 1 September 2020 and 1 April 2023, 44 patients (median age, 44 years) had a C. diphtheriae-positive clinical culture, with most detections occurring after March 2022. Patients were predominantly male (75%), White (66%), unstably housed (77%), and had a lifetime history of injecting drugs (75%). Most C. diphtheriae-positive cultures were polymicrobial, including wound cultures from 36 (82%) patients and blood cultures from 6 (14%) patients, not mutually exclusive. Thirty-four patients (77%), including all 5 patients with C. diphtheriae IE, required hospital admission for C. diphtheriae or a related condition. Of the 5 patients with IE, 3 died of IE and 1 from COVID-19.
    Conclusions: Findings suggest a high-morbidity outbreak disproportionately affecting patients who use substances and are unstably housed.
    MeSH term(s) Humans ; Male ; Adult ; Female ; Washington/epidemiology ; Middle Aged ; Corynebacterium diphtheriae/isolation & purification ; Diphtheria/epidemiology ; Diphtheria/microbiology ; Endocarditis, Bacterial/epidemiology ; Endocarditis, Bacterial/microbiology ; Young Adult ; Aged ; Anti-Bacterial Agents/therapeutic use ; Endocarditis/microbiology ; Endocarditis/epidemiology
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciae094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1505: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: The Effect of the Shikamana Peer-and-Provider Intervention on Depressive Symptoms, Alcohol Use, and Other Drug Use Among Gay, Bisexual, and Other Men Who Have Sex with Men in Kenya.

    Graff, Nicholas R / Hong, Chenglin / Guthrie, Brandon / Micheni, Murugi / Chirro, Oscar / Wahome, Elizabeth / van der Elst, Elise / Sanders, Eduard J / Simoni, Jane M / Graham, Susan M

    AIDS and behavior

    2023  Volume 27, Issue 9, Page(s) 3053–3063

    Abstract: Kenyan gay, bisexual, and other men who have sex with men (GBMSM) face stigma and discrimination, which may adversely impact mental health and limit antiretroviral therapy (ART) adherence among GBMSM living with HIV. We evaluated whether the Shikamana ... ...

    Abstract Kenyan gay, bisexual, and other men who have sex with men (GBMSM) face stigma and discrimination, which may adversely impact mental health and limit antiretroviral therapy (ART) adherence among GBMSM living with HIV. We evaluated whether the Shikamana peer-and-provider intervention, which improved ART adherence among participants in a small randomized trial, was associated with changes in mental health or substance use. The intervention was associated with a significant decrease in PHQ-9 score between baseline and month 6 (estimated change - 2.7, 95% CI - 5.2 to - 0.2, p = 0.037) compared to standard care. In an exploratory analysis, each one-point increment in baseline HIV stigma score was associated with a - 0.7 point (95% CI - 1.3 to - 0.04, p = 0.037) greater decrease in PHQ-9 score over the study period in the intervention group. Additional research is required to understand factors that influence this intervention's effects on mental health outcomes.
    MeSH term(s) Humans ; Male ; Anti-Retroviral Agents/therapeutic use ; Depression/drug therapy ; Depression/epidemiology ; Depression/psychology ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; HIV Infections/psychology ; Homosexuality, Male/psychology ; Kenya/epidemiology ; Sexual and Gender Minorities ; Substance-Related Disorders/epidemiology ; Substance-Related Disorders/psychology ; Randomized Controlled Trials as Topic
    Chemical Substances Anti-Retroviral Agents
    Language English
    Publishing date 2023-03-16
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1339885-4
    ISSN 1573-3254 ; 1090-7165
    ISSN (online) 1573-3254
    ISSN 1090-7165
    DOI 10.1007/s10461-023-04027-x
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  4. Article ; Online: Repeated introductions and intensive community transmission fueled a mumps virus outbreak in Washington State.

    Moncla, Louise H / Black, Allison / DeBolt, Chas / Lang, Misty / Graff, Nicholas R / Pérez-Osorio, Ailyn C / Müller, Nicola F / Haselow, Dirk / Lindquist, Scott / Bedford, Trevor

    eLife

    2021  Volume 10

    Abstract: In 2016/2017, Washington State experienced a mumps outbreak despite high childhood vaccination rates, with cases more frequently detected among school-aged children and members of the Marshallese community. We sequenced 166 mumps virus genomes collected ... ...

    Abstract In 2016/2017, Washington State experienced a mumps outbreak despite high childhood vaccination rates, with cases more frequently detected among school-aged children and members of the Marshallese community. We sequenced 166 mumps virus genomes collected in Washington and other US states, and traced mumps introductions and transmission within Washington. We uncover that mumps was introduced into Washington approximately 13 times, primarily from Arkansas, sparking multiple co-circulating transmission chains. Although age and vaccination status may have impacted transmission, our data set could not quantify their precise effects. Instead, the outbreak in Washington was overwhelmingly sustained by transmission within the Marshallese community. Our findings underscore the utility of genomic data to clarify epidemiologic factors driving transmission and pinpoint contact networks as critical for mumps transmission. These results imply that contact structures and historic disparities may leave populations at increased risk for respiratory virus disease even when a vaccine is effective and widely used.
    MeSH term(s) Adolescent ; Adult ; Child ; Child, Preschool ; Disease Outbreaks/statistics & numerical data ; Genome, Viral ; Humans ; Infant ; Micronesia/ethnology ; Middle Aged ; Mumps/epidemiology ; Mumps/transmission ; Mumps/virology ; Mumps virus/genetics ; Mumps virus/physiology ; Washington/epidemiology ; Young Adult
    Language English
    Publishing date 2021-04-19
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.66448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Coronavirus Disease among Workers in Food Processing, Food Manufacturing, and Agriculture Workplaces.

    Waltenburg, Michelle A / Rose, Charles E / Victoroff, Tristan / Butterfield, Marilee / Dillaha, Jennifer A / Heinzerling, Amy / Chuey, Meagan / Fierro, Maria / Jervis, Rachel H / Fedak, Kristen M / Leapley, Andrea / Gabel, Julie A / Feldpausch, Amanda / Dunne, Eileen M / Austin, Connie / Pedati, Caitlin S / Ahmed, Farah S / Tubach, Sheri / Rhea, Charles /
    Tonzel, Julius / Krueger, Anna / Crum, David A / Vostok, Johanna / Moore, Michael J / Kempher, Hannah / Scheftel, Joni / Turabelidze, George / Stover, Derry / Donahue, Matthew / Thomas, Deepam / Edge, Karen / Gutierrez, Bernadette / Berl, Erica / McLafferty, Meagan / Kline, Kelly E / Martz, Nichole / Rajotte, James C / Julian, Ernest / Diedhiou, Abdoulaye / Radcliffe, Rachel / Clayton, Joshua L / Ortbahn, Dustin / Cummins, Jason / Barbeau, Bree / Carpenter, Stacy / Pringle, Julia C / Murphy, Julia / Darby, Brandy / Graff, Nicholas R / Dostal, Tia K H / Pray, Ian W / Tillman, Courtney / Rose, Dale A / Honein, Margaret A

    Emerging infectious diseases

    2020  Volume 27, Issue 1

    Abstract: We describe coronavirus disease (COVID-19) among US food manufacturing and agriculture workers and provide updated information on meat and poultry processing workers. Among 742 food and agriculture workplaces in 30 states, 8,978 workers had confirmed ... ...

    Abstract We describe coronavirus disease (COVID-19) among US food manufacturing and agriculture workers and provide updated information on meat and poultry processing workers. Among 742 food and agriculture workplaces in 30 states, 8,978 workers had confirmed COVID-19; 55 workers died. Racial and ethnic minority workers could be disproportionately affected by COVID-19.
    MeSH term(s) Adult ; Aged ; Agriculture ; COVID-19/epidemiology ; COVID-19/transmission ; Female ; Food Industry ; Humans ; Male ; Middle Aged ; SARS-CoV-2 ; United States/epidemiology ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-10-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2701.203821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
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  6. Article ; Online: Update: COVID-19 Among Workers in Meat and Poultry Processing Facilities - United States, April-May 2020.

    Waltenburg, Michelle A / Victoroff, Tristan / Rose, Charles E / Butterfield, Marilee / Jervis, Rachel H / Fedak, Kristen M / Gabel, Julie A / Feldpausch, Amanda / Dunne, Eileen M / Austin, Connie / Ahmed, Farah S / Tubach, Sheri / Rhea, Charles / Krueger, Anna / Crum, David A / Vostok, Johanna / Moore, Michael J / Turabelidze, George / Stover, Derry /
    Donahue, Matthew / Edge, Karen / Gutierrez, Bernadette / Kline, Kelly E / Martz, Nichole / Rajotte, James C / Julian, Ernest / Diedhiou, Abdoulaye / Radcliffe, Rachel / Clayton, Joshua L / Ortbahn, Dustin / Cummins, Jason / Barbeau, Bree / Murphy, Julia / Darby, Brandy / Graff, Nicholas R / Dostal, Tia K H / Pray, Ian W / Tillman, Courtney / Dittrich, Michelle M / Burns-Grant, Gail / Lee, Sooji / Spieckerman, Alisa / Iqbal, Kashif / Griffing, Sean M / Lawson, Alicia / Mainzer, Hugh M / Bealle, Andreea E / Edding, Erika / Arnold, Kathryn E / Rodriguez, Tomas / Merkle, Sarah / Pettrone, Kristen / Schlanger, Karen / LaBar, Kristin / Hendricks, Kate / Lasry, Arielle / Krishnasamy, Vikram / Walke, Henry T / Rose, Dale A / Honein, Margaret A

    MMWR. Morbidity and mortality weekly report

    2020  Volume 69, Issue 27, Page(s) 887–892

    Abstract: Meat and poultry processing facilities face distinctive challenges in the control of infectious diseases, including coronavirus disease 2019 (COVID-19) (1). COVID-19 outbreaks among meat and poultry processing facility workers can rapidly affect large ... ...

    Abstract Meat and poultry processing facilities face distinctive challenges in the control of infectious diseases, including coronavirus disease 2019 (COVID-19) (1). COVID-19 outbreaks among meat and poultry processing facility workers can rapidly affect large numbers of persons. Assessment of COVID-19 cases among workers in 115 meat and poultry processing facilities through April 27, 2020, documented 4,913 cases and 20 deaths reported by 19 states (1). This report provides updated aggregate data from states regarding the number of meat and poultry processing facilities affected by COVID-19, the number and demographic characteristics of affected workers, and the number of COVID-19-associated deaths among workers, as well as descriptions of interventions and prevention efforts at these facilities. Aggregate data on confirmed COVID-19 cases and deaths among workers identified and reported through May 31, 2020, were obtained from 239 affected facilities (those with a laboratory-confirmed COVID-19 case in one or more workers) in 23 states.* COVID-19 was confirmed in 16,233 workers, including 86 COVID-19-related deaths. Among 14 states reporting the total number of workers in affected meat and poultry processing facilities (112,616), COVID-19 was diagnosed in 9.1% of workers. Among 9,919 (61%) cases in 21 states with reported race/ethnicity, 87% occurred among racial and ethnic minority workers. Commonly reported interventions and prevention efforts at facilities included implementing worker temperature or symptom screening and COVID-19 education, mandating face coverings, adding hand hygiene stations, and adding physical barriers between workers. Targeted workplace interventions and prevention efforts that are appropriately tailored to the groups most affected by COVID-19 are critical to reducing both COVID-19-associated occupational risk and health disparities among vulnerable populations. Implementation of these interventions and prevention efforts
    MeSH term(s) Adult ; Animals ; COVID-19 ; Coronavirus Infections/epidemiology ; Disease Outbreaks ; Female ; Food-Processing Industry ; Humans ; Male ; Meat ; Middle Aged ; Occupational Diseases/epidemiology ; Pandemics ; Pneumonia, Viral/epidemiology ; Poultry ; United States/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-07-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 412775-4
    ISSN 1545-861X ; 0149-2195
    ISSN (online) 1545-861X
    ISSN 0149-2195
    DOI 10.15585/mmwr.mm6927e2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Coronavirus Disease among Workers in Food Processing, Food Manufacturing, and Agriculture Workplaces

    Waltenburg, Michelle A / Rose, Charles E / Victoroff, Tristan / Butterfield, Marilee / Dillaha, Jennifer A / Heinzerling, Amy / Chuey, Meagan / Fierro, Maria / Jervis, Rachel H / Fedak, Kristen M / Leapley, Andrea / Gabel, Julie A / Feldpausch, Amanda / Dunne, Eileen M / Austin, Connie / Pedati, Caitlin S / Ahmed, Farah S / Tubach, Sheri / Rhea, Charles /
    Tonzel, Julius / Krueger, Anna / Crum, David A / Vostok, Johanna / Moore, Michael J / Kempher, Hannah / Scheftel, Joni / Turabelidze, George / Stover, Derry / Donahue, Matthew / Thomas, Deepam / Edge, Karen / Gutierrez, Bernadette / Berl, Erica / McLafferty, Meagan / Kline, Kelly E / Martz, Nichole / Rajotte, James C / Julian, Ernest / Diedhiou, Abdoulaye / Radcliffe, Rachel / Clayton, Joshua L / Ortbahn, Dustin / Cummins, Jason / Barbeau, Bree / Carpenter, Stacy / Pringle, Julia C / Murphy, Julia / Darby, Brandy / Graff, Nicholas R / Dostal, Tia K H

    Emerg. infect. dis

    Abstract: We describe coronavirus disease (COVID-19) among US food manufacturing and agriculture workers and provide updated information on meat and poultry processing workers. Among 742 food and agriculture workplaces in 30 states, 8,978 workers had confirmed ... ...

    Abstract We describe coronavirus disease (COVID-19) among US food manufacturing and agriculture workers and provide updated information on meat and poultry processing workers. Among 742 food and agriculture workplaces in 30 states, 8,978 workers had confirmed COVID-19; 55 workers died. Racial and ethnic minority workers could be disproportionately affected by COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #884956
    Database COVID19

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