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  1. Article: Neuromuscular Electrical Stimulation in Patients With Severe COVID-19 Associated With Sepsis and Septic Shock.

    Righetti, Renato Fraga / Grams, Samantha Torres / Costa, Wesla Neves da Silva / Saraiva, Leandro Teixeira / de Salles, Isabel Chateaubriand Diniz / Yamaguti, Wellington Pereira

    Frontiers in medicine

    2022  Volume 9, Page(s) 751636

    Abstract: Background: Neuromuscular electrical stimulation (NMES) can be applied to critically ill patients. However, its results on muscle strength and functionality in patients with COVID-19 are unknown.: Objective: Evaluate the effects of intervention with ... ...

    Abstract Background: Neuromuscular electrical stimulation (NMES) can be applied to critically ill patients. However, its results on muscle strength and functionality in patients with COVID-19 are unknown.
    Objective: Evaluate the effects of intervention with NMES on muscle mass and functionality of patients with severe COVID-19 associated with sepsis and septic shock.
    Methods: Seven patients with COVID-19 associated with sepsis or septic shock were selected, but only 5 patients completed all days of the intervention with NMES. The intervention was performed by a single physiotherapist on 7 consecutive days in a daily session of 40 min. The outcome measures were the femoris cross-sectional area; thickness of the anterior compartment of the quadriceps muscle; rectus femoris echogenicity; International Classification of Functioning, Disability, and Health (ICF)-muscle strength; PFIT-s, DEMMI, and the SOMS; feasibility, and safety. The patients were evaluated on days 1, 5, and 8.
    Results: The rectus femoris cross-sectional area decreased significantly from days 1 to 8, but showed maintenance of the thickness of the anterior compartment of the quadriceps muscle from days 1 to 8. The MRC score increased significantly from days 1 to 5 and kept this improvement until day 8. All patients showed an increase in the MRC score and reduction of the ICF-muscle strength, meaning improved muscle strength from days 1 to 8. The PFIT-s increased significantly from days 1 to 5 and improved until day 8 compared to day 5. DEMMI and SOMS score increased significantly on day 8 compared to days 1 and 5.
    Conclusion: Rehabilitation with NMES showed improvement in muscle strength and functionality of patients in this study with a potential protective effect on muscle mass loss in patients with critical COVID-19 associated with sepsis and septic shock. This study is the first report of the potential effects of neuromuscular electrical stimulation in patients with severe COVID-19 associated with sepsis and septic shock.
    Language English
    Publishing date 2022-02-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.751636
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Adjunctive Use of Noninvasive Ventilation During Exercise in Patients With Decompensated Heart Failure.

    Moraes, Igor Gutierrez / Kimoto, Karen Mota / Fernandes, Marcos Brandmuller / Grams, Samantha Torres / Yamaguti, Wellington Pereira

    The American journal of cardiology

    2017  Volume 119, Issue 3, Page(s) 423–427

    Abstract: Noninvasive ventilation (NIV) as an adjunct strategy for increasing exercise tolerance has been widely investigated in patients with pulmonary diseases. To our knowledge, there are no studies that have used NIV during exercise in patients with ... ...

    Abstract Noninvasive ventilation (NIV) as an adjunct strategy for increasing exercise tolerance has been widely investigated in patients with pulmonary diseases. To our knowledge, there are no studies that have used NIV during exercise in patients with decompensated heart failure (HF). The aim of this study was to evaluate the effects of NIV on exercise tolerance in hospitalized patients with decompensated HF. Thirteen patients (77 ± 15 years) with a mean left ventricular ejection fraction of 35 ± 15% were included. Patients underwent 2 submaximal exercise tests with constant load for lower limbs using a portable cycle ergometer. Tests were performed on the same day with a 60-minute interval between each one, using a randomized crossover design: sham ventilation (continuous positive airway pressure mode, 4 cm H
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Continuous Positive Airway Pressure/methods ; Cross-Over Studies ; Double-Blind Method ; Dyspnea/therapy ; Exercise ; Exercise Test ; Exercise Tolerance ; Female ; Heart Failure/therapy ; Hospitalization ; Humans ; Male ; Middle Aged ; Noninvasive Ventilation/methods ; Stroke Volume ; Ventricular Dysfunction, Left
    Language English
    Publishing date 2017-02-01
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2016.10.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Reference equations for handgrip strength: Normative values in young adult and middle-aged subjects

    Lopes, Jordão / da Silva, Edy Floriano / de Brito, Christina May Moran / de Medeiros, Luana Adriano / Grams, Samantha Torres / Yamaguti, Wellington Pereira

    Clinical nutrition. 2018 June, v. 37, no. 3

    2018  

    Abstract: Handgrip strength (HS) has been widely used as a functionality parameter of the upper limbs (UL) and general health. The measurement of HS by dynamometry is a low cost, non-invasive method of simple applicability, widely used in pulmonary rehabilitation ... ...

    Abstract Handgrip strength (HS) has been widely used as a functionality parameter of the upper limbs (UL) and general health. The measurement of HS by dynamometry is a low cost, non-invasive method of simple applicability, widely used in pulmonary rehabilitation and in critical care units. However, there are no reports in the literature of reference equations for the Brazilian population involving young and middle-aged adults. The aim of this study was to establish reference equations to predict normal HS for young and middle-aged adults through demographic and anthropometric data.This is a cross-sectional study with a sample of 80 healthy subjects (40 men and 40 women), aged 20–60 years. Inclusion criteria were: 1) BMI between 18.5 and 30 kg/m2; 2) presence of dominant hand; 3) no cardiac, pulmonary, metabolic, or neurologic diseases; 4) lack of musculoskeletal disorders; 5) no history of fractures or trauma of the UL. Anthropometric measurements of the UL were obtained by a tape (hand length and width, forearm circumference and length). The dominance of hands was defined by the Dutch Handedness Questionnaire. HS measures were obtained by a manual hydraulic dynamometer, according to the recommendations of the American Association of Hand Therapists. Data were analyzed with SPSS for Windows, version 17.0, and treated with descriptive and inferential analysis. Normality was evaluated by Kolmogorov–Smirnov. Pearson or Spearman coefficients and multiple regression analysis were also used.HS was significantly higher for men compared to women, and also higher for the dominant hand (HSD) compared to the non-dominant hand (HSND) (p < 0.05). No significant differences were found for HS between the age groups 20–30, 30–40, 40–50 and 50–60 years (p > 0.05). No correlation was found between HS and age. A weak correlation was found between HS and BMI. A moderate correlation of HS was observed with weight and height. Finally, moderate and high correlations were found between HS and anthropometric variables of UL. The best reference equations with R2, adjusted to 0.71 and 0.70, were respectively: HSDkg = −15.490 + (10.787 × Gender male=1; female=0) + (0.558 × Forearm circumference) + (1.763 × Hand Length); HSNDkg = −9.887 + (12.832 × Gender male=1; female=0) + (2.028 × Hand Length).The variability of HS is largely explained by gender, forearm circumference, and hand length.
    Keywords body mass index ; cross-sectional studies ; data analysis ; equations ; gender ; hands ; men ; middle-aged adults ; musculoskeletal diseases ; questionnaires ; regression analysis ; women ; young adults
    Language English
    Dates of publication 2018-06
    Size p. 914-918.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2017.03.018
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Reference equations for handgrip strength: Normative values in young adult and middle-aged subjects.

    Lopes, Jordão / Grams, Samantha Torres / da Silva, Edy Floriano / de Medeiros, Luana Adriano / de Brito, Christina May Moran / Yamaguti, Wellington Pereira

    Clinical nutrition (Edinburgh, Scotland)

    2017  Volume 37, Issue 3, Page(s) 914–918

    Abstract: Background & aims: Handgrip strength (HS) has been widely used as a functionality parameter of the upper limbs (UL) and general health. The measurement of HS by dynamometry is a low cost, non-invasive method of simple applicability, widely used in ... ...

    Abstract Background & aims: Handgrip strength (HS) has been widely used as a functionality parameter of the upper limbs (UL) and general health. The measurement of HS by dynamometry is a low cost, non-invasive method of simple applicability, widely used in pulmonary rehabilitation and in critical care units. However, there are no reports in the literature of reference equations for the Brazilian population involving young and middle-aged adults. The aim of this study was to establish reference equations to predict normal HS for young and middle-aged adults through demographic and anthropometric data.
    Methods: This is a cross-sectional study with a sample of 80 healthy subjects (40 men and 40 women), aged 20-60 years. Inclusion criteria were: 1) BMI between 18.5 and 30 kg/m
    Results: HS was significantly higher for men compared to women, and also higher for the dominant hand (HSD) compared to the non-dominant hand (HSND) (p < 0.05). No significant differences were found for HS between the age groups 20-30, 30-40, 40-50 and 50-60 years (p > 0.05). No correlation was found between HS and age. A weak correlation was found between HS and BMI. A moderate correlation of HS was observed with weight and height. Finally, moderate and high correlations were found between HS and anthropometric variables of UL. The best reference equations with R
    Conclusion: The variability of HS is largely explained by gender, forearm circumference, and hand length.
    MeSH term(s) Adult ; Age Factors ; Anthropometry ; Body Height ; Body Mass Index ; Body Weight ; Brazil ; Cross-Sectional Studies ; Female ; Functional Laterality ; Hand Strength ; Humans ; Male ; Middle Aged ; Reference Values ; Sex Factors ; Young Adult
    Language English
    Publishing date 2017-03-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2017.03.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Unidirectional Expiratory Valve Method to Assess Maximal Inspiratory Pressure in Individuals without Artificial Airway.

    Grams, Samantha Torres / Kimoto, Karen Yumi Mota / Azevedo, Elen Moda de Oliveira / Lança, Marina / Albuquerque, André Luis Pereira de / Brito, Christina May Moran de / Yamaguti, Wellington Pereira

    PloS one

    2015  Volume 10, Issue 9, Page(s) e0137825

    Abstract: Introduction: Maximal Inspiratory Pressure (MIP) is considered an effective method to estimate strength of inspiratory muscles, but still leads to false positive diagnosis. Although MIP assessment with unidirectional expiratory valve method has been ... ...

    Abstract Introduction: Maximal Inspiratory Pressure (MIP) is considered an effective method to estimate strength of inspiratory muscles, but still leads to false positive diagnosis. Although MIP assessment with unidirectional expiratory valve method has been used in patients undergoing mechanical ventilation, no previous studies investigated the application of this method in subjects without artificial airway.
    Objectives: This study aimed to compare the MIP values assessed by standard method (MIPsta) and by unidirectional expiratory valve method (MIPuni) in subjects with spontaneous breathing without artificial airway. MIPuni reproducibility was also evaluated.
    Methods: This was a crossover design study, and 31 subjects performed MIPsta and MIPuni in a random order. MIPsta measured MIP maintaining negative pressure for at least one second after forceful expiration. MIPuni evaluated MIP using a unidirectional expiratory valve attached to a face mask and was conducted by two evaluators (A and B) at two moments (Tests 1 and 2) to determine interobserver and intraobserver reproducibility of MIP values. Intraclass correlation coefficient (ICC[2,1]) was used to determine intraobserver and interobserver reproducibility.
    Results: The mean values for MIPuni were 14.3% higher (-117.3 ± 24.8 cmH2O) than the mean values for MIPsta (-102.5 ± 23.9 cmH2O) (p<0.001). Interobserver reproducibility assessment showed very high correlation for Test 1 (ICC[2,1] = 0.91), and high correlation for Test 2 (ICC[2,1] = 0.88). The assessment of the intraobserver reproducibility showed high correlation for evaluator A (ICC[2,1] = 0.86) and evaluator B (ICC[2,1] = 0.77).
    Conclusions: MIPuni presented higher values when compared with MIPsta and proved to be reproducible in subjects with spontaneous breathing without artificial airway.
    MeSH term(s) Adult ; Cross-Over Studies ; Humans ; Inhalation ; Male ; Muscle Strength ; Observer Variation ; Pressure ; Reproducibility of Results ; Respiration, Artificial/methods ; Respiratory Function Tests ; Respiratory Muscles/physiology ; Young Adult
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0137825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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