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  1. Book ; Online: Clostridioides difficile Infection

    Granata, Guido

    2022  

    Keywords Medicine ; Epidemiology & medical statistics ; Clostridioides difficile infection ; co-morbidities ; mortality ; malignancy ; outcome ; risk factors ; C. difficile infection ; molecular analysis ; toxin production ; antibiotic resistance ; microbiome ; C. difficile ; hamsters ; bovine immunoglobulins ; 16S rRNA ; next generation sequencing ; Clostridioides difficile ; Charlson comorbidity index ; Child-Pugh score ; Clostridioides difficile associated disease ; CDI ; nonalcoholic fatty liver disease ; NAFLD ; NASH ; recurrent disease ; antibacterial ; Clostridioides (Clostridium) difficile ; peptidomimetic ; triazole ; baicalin ; gut dysbiosis ; mouse model ; spores ; anti-spore ; spore germination ; nanomaterial ; teicoplanin ; spore ; antibiotics ; multi-step algorithm ; multiplex "real-time" PCR ; PCR capillary-based electrophoresis ribotyping ; Clostridium difficile ; TcdA ; TcdB ; toxin ; toxemia ; plasma ; method ; quantification ; CDI severity ; n/a
    Language 0|e
    Size 1 electronic resource (178 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021614330
    ISBN 9783036538778 ; 3036538771
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Clostridioides difficile infection

    Granata, Guido

    2022  

    Author's details Editor Guido Granata
    Language English
    Size 1 Online-Ressource (ix, 165 Seiten), Illustrationen, Diagramme
    Publisher MDPI
    Publishing place Basel
    Publishing country Switzerland
    Document type Book ; Online
    Note This book is a reprint of the Special Issue "Clostridioides difficile infection" that was published in "Antibiotics" ; Open Access
    HBZ-ID HT021462087
    ISBN 978-3-0365-3877-8 ; 9783036538785 ; 3-0365-3877-1 ; 303653878X
    DOI 10.3390/books978-3-0365-3877-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: Editorial:

    Granata, Guido / Barbut, Frédéric / Petrosillo, Nicola

    Frontiers in medicine

    2024  Volume 11, Page(s) 1372813

    Language English
    Publishing date 2024-02-26
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2024.1372813
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Gram Negatives and Antimicrobial Resistance: Two Faces of the Same Coin.

    Petrosillo, Nicola / Granata, Guido

    Journal of clinical medicine

    2022  Volume 11, Issue 19

    Abstract: The evolution, emergence and spread of bacterial antimicrobial resistance (AMR) represent threatening healthcare concerns of worldwide proportions [ ... ]. ...

    Abstract The evolution, emergence and spread of bacterial antimicrobial resistance (AMR) represent threatening healthcare concerns of worldwide proportions [...].
    Language English
    Publishing date 2022-09-22
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11195574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Tackling

    Granata, Guido / Taglietti, Fabrizio / Petrosillo, Nicola

    Journal of clinical medicine

    2023  Volume 12, Issue 16

    Abstract: Globally, multidrug-resistant (MDR) bacteria represent a menace to public health [ ... ]. ...

    Abstract Globally, multidrug-resistant (MDR) bacteria represent a menace to public health [...].
    Language English
    Publishing date 2023-08-08
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12165168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Clostridioides difficile

    Granata, Guido / Schiavone, Francesco / Taglietti, Fabrizio / Petrosillo, Nicola

    Journal of clinical medicine

    2023  Volume 12, Issue 15

    Abstract: Clostridioides ... ...

    Abstract Clostridioides difficile
    Language English
    Publishing date 2023-07-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12154997
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Introduction to the Special Issue on

    Granata, Guido / Donno, Davide Roberto

    Antibiotics (Basel, Switzerland)

    2021  Volume 10, Issue 10

    Abstract: The Gram-positive, anaerobic ... ...

    Abstract The Gram-positive, anaerobic bacterium
    Language English
    Publishing date 2021-10-11
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics10101233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Bezlotoxumab in Patients with a Primary

    Granata, Guido / Schiavone, Francesco / Pipitone, Giuseppe

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 11

    Abstract: Background: Nowadays, one of the main issues in the management of : Objectives: To assess the available evidence on the use of bezlotoxumab for the prevention of rCDI during a first CDI episode.: Methods: Published articles on bezlotoxumab during ... ...

    Abstract Background: Nowadays, one of the main issues in the management of
    Objectives: To assess the available evidence on the use of bezlotoxumab for the prevention of rCDI during a first CDI episode.
    Methods: Published articles on bezlotoxumab during a primary CDI episode were identified through computerized literature searches with the search terms [(bezlotoxumab) AND (CDI) OR (
    Results: Eighty-eight studies were identified as published from December 2014 to June 2022. Five studies were included in this study, one was a phase III clinical trial and four were sub-analyses or extensions of the previous phase III clinical trial. In the phase III clinical trial, the subgroup analysis on the included primary CDI patients showed that 13.5% of patients receiving bezlotoxumab had an rCDI, whilst 20.9% of patients in the placebo group had an rCDI at the twelve weeks follow-up (absolute difference: -7.4).
    Conclusions: Bezlotoxumab administration during the standard of care antibiotic therapy is effective and safe in reducing the rate of rCDI. Despite its high cost, evidence suggests considering bezlotoxumab in patients with a primary CDI episode. Further studies are needed to assess the benefit in specific subgroups of primary CDI patients and to define the risk factors to guide bezlotoxumab use.
    Language English
    Publishing date 2022-10-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11111495
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Durlobactam in the Treatment of Multidrug-Resistant

    Granata, Guido / Taglietti, Fabrizio / Schiavone, Francesco / Petrosillo, Nicola

    Journal of clinical medicine

    2022  Volume 11, Issue 12

    Abstract: ... A. ... ...

    Abstract A. baumannii
    Language English
    Publishing date 2022-06-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11123258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Antibiotics Use in COVID-19 Patients: A Systematic Literature Review.

    Granata, Guido / Schiavone, Francesco / Pipitone, Giuseppe / Taglietti, Fabrizio / Petrosillo, Nicola

    Journal of clinical medicine

    2022  Volume 11, Issue 23

    Abstract: The issue of bacterial infections in COVID-19 patients has received increasing attention among scientists. Antibiotics were widely prescribed during the early phase of the pandemic. We performed a literature review to assess the reasons, evidence and ... ...

    Abstract The issue of bacterial infections in COVID-19 patients has received increasing attention among scientists. Antibiotics were widely prescribed during the early phase of the pandemic. We performed a literature review to assess the reasons, evidence and practices on the use of antibiotics in COVID-19 in- and outpatients. Published articles providing data on antibiotics use in COVID-19 patients were identified through computerized literature searches on the MEDLINE and SCOPUS databases. Searching the MEDLINE database, the following search terms were adopted: ((antibiotic) AND (COVID-19)). Searching the SCOPUS database, the following search terms were used: ((antibiotic treatment) AND (COVID-19)). The risk of bias in the included studies was not assessed. Both quantitative and qualitative information were summarized by means of textual descriptions. Five-hundred-ninety-three studies were identified, published from January 2020 to 30 October 2022. Thirty-six studies were included in this systematic review. Of the 36 included studies, 32 studies were on the use of antibiotics in COVID-19 inpatients and 4 on antibiotic use in COVID-19 outpatients. Apart from the studies identified and included in the review, the main recommendations on antibiotic treatment from 5 guidelines for the clinical management of COVID-19 were also summarized in a separate paragraph. Antibiotics should not be prescribed during COVID-19 unless there is a strong clinical suspicion of bacterial coinfection or superinfection.
    Language English
    Publishing date 2022-12-04
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11237207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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