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  1. Article ; Online: Comments on "Current status and quality of radiomic studies for predicting KRAS mutations in colorectal cancer patients: A systematic review and meta-analysis".

    Fusco, Roberta / Granata, Vincenza

    European journal of radiology

    2023  Volume 169, Page(s) 111192

    Abstract: We read with interest the article from Dr Jia LL and colleagues in Eur J Radiol in which they assessed the methodological quality of radiomics-based studies for non-invasive preoperative prediction of Kirsten rat sarcoma (KRAS) mutations in patients with ...

    Abstract We read with interest the article from Dr Jia LL and colleagues in Eur J Radiol in which they assessed the methodological quality of radiomics-based studies for non-invasive preoperative prediction of Kirsten rat sarcoma (KRAS) mutations in patients with colorectal cancer. They systematically evaluated the prediction models diagnostic accuracy of twenty-nine studies between February 2014 and March 2022 and we congratulate the Authors on their accuracy in reporting recent published manuscript about radiomics-based studies to predict KRAS mutations in patients with colorectal cancer however they did not report the impact of contrast administration and the different phases of the contrast study (arterial, portal and transient phase) compared to the EOB phase in this research field.
    MeSH term(s) Humans ; Proto-Oncogene Proteins p21(ras)/genetics ; Colorectal Neoplasms/diagnostic imaging ; Colorectal Neoplasms/genetics ; Mutation
    Chemical Substances Proto-Oncogene Proteins p21(ras) (EC 3.6.5.2) ; KRAS protein, human
    Language English
    Publishing date 2023-11-10
    Publishing country Ireland
    Document type Meta-Analysis ; Systematic Review ; Letter
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2023.111192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1630: Show issues Location:
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  2. Article ; Online: Effect of microplastics on urban wastewater disinfection and impact on effluent reuse: Sunlight/H

    Adeel, Mister / Granata, Veronica / Carapella, Giovanni / Rizzo, Luigi

    Journal of hazardous materials

    2023  Volume 465, Page(s) 133102

    Abstract: The interference of three types of microplastics (MPs) on the inactivation of Escherichia coli (E. coli) by advanced oxidation processes (AOPs) (namely, sunlight/ ... ...

    Abstract The interference of three types of microplastics (MPs) on the inactivation of Escherichia coli (E. coli) by advanced oxidation processes (AOPs) (namely, sunlight/H
    MeSH term(s) Wastewater ; Disinfection/methods ; Escherichia coli ; Hydrogen Peroxide/chemistry ; Microplastics/pharmacology ; Plastics ; Iron/chemistry ; Sunlight ; Hydrogen-Ion Concentration ; Oxidation-Reduction
    Chemical Substances Wastewater ; Hydrogen Peroxide (BBX060AN9V) ; Microplastics ; Plastics ; Iron (E1UOL152H7)
    Language English
    Publishing date 2023-11-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.133102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of the substrate on the electrical transport and fluctuation processes in NbRe and NbReN ultrathin films for superconducting electronics applications.

    Barone, C / Cirillo, C / Carapella, G / Granata, V / Santoro, D / Attanasio, C / Pagano, S

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 1573

    Abstract: NbRe-based superconducting thin films recently received relevant interest in the field of low-temperature electronics. However, for these materials the electrical conduction mechanisms, in particular in the normal state, still need to be investigated in ... ...

    Abstract NbRe-based superconducting thin films recently received relevant interest in the field of low-temperature electronics. However, for these materials the electrical conduction mechanisms, in particular in the normal state, still need to be investigated in more detail. Here, NbRe and NbReN films of different thicknesses have been deposited on two different substrates, namely monocrystalline Si and [Formula: see text] buffered Si. The films were characterized by DC electrical transport measurements. Moreover, a connection with the charge carriers fluctuation processes has been made by analyzing the electrical noise generated in the normal state region. Despite the films morphology seems not to be affected by the substrate used, a lower noise level has been found for the ones grown on [Formula: see text], in particular for NbReN. From this study it emerges that both NbRe and NbReN ultrathin films are of very good quality, as far as the low-temperature electrical noise and conduction are concerned, with noise levels competitive with NbN. These results may further support the proposal of using these materials in a nanowire form in the field of superconducting electronics.
    Language English
    Publishing date 2022-01-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-05511-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Optimal imaging before local therapy of colorectal liver metastases.

    Granata, Vincenza / Petrillo, Antonella / Setola, Sergio Venanzio / Izzo, Francesco / Fusco, Roberta

    The Lancet. Oncology

    2024  Volume 25, Issue 3, Page(s) e100

    MeSH term(s) Humans ; Colorectal Neoplasms/diagnostic imaging ; Colorectal Neoplasms/pathology ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/secondary
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Letter
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(24)00033-0
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5696: Show issues Location:
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    Zs.MO 460: Show issues

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  5. Article: Incidental Focal Spleen Lesions: Integrated Imaging and Pattern Recognition Approach to the Differential Diagnosis.

    Corvino, Antonio / Granata, Vincenza / Tafuri, Domenico / Cocco, Giulio / Catalano, Orlando

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 15

    Abstract: Spleen lesions and pseudolesions, detected incidentally in imaging, are not uncommon and may require further work-up. The imaging appearance of focal splenic lesions (FSLs) may not be pathognomonic, because of considerably overlapping features. ... ...

    Abstract Spleen lesions and pseudolesions, detected incidentally in imaging, are not uncommon and may require further work-up. The imaging appearance of focal splenic lesions (FSLs) may not be pathognomonic, because of considerably overlapping features. Consequently, all imaging techniques lack specificity to fully characterize FSLs. Clinical correlation is mandatory, so as, first of all, to categorize the patient as having or not having a history of solid or hematologic malignancy. Nowadays, many patients have old imaging studies available for comparison and, consequently, it is important to understand if the lesion was previously present or not, and if the size is the same or has changed. In the absence of comparison studies, and with a lack of imaging features of benignity, further investigation may be necessary, using PET, biopsy, or short-term follow-up. Some algorithms have been proposed to manage incidental FSLs; however, none of these strategies has been validated by prospective studies to date. In this review we illustrate the topic of incidental FSLs and we analyze a number of published algorithms.
    Language English
    Publishing date 2023-07-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13152536
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  6. Article: Commentary: The Synergistic Role of Irreversible Electroporation and Chemotherapy for Locally Advanced Pancreatic Cancer.

    Granata, Vincenza / Palaia, Raffaele / Izzo, Francesco

    Frontiers in oncology

    2022  Volume 12, Page(s) 955444

    Language English
    Publishing date 2022-09-15
    Publishing country Switzerland
    Document type Journal Article ; Comment
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.955444
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  7. Article ; Online: Guiding antiferromagnetic transitions in Ca[Formula: see text]RuO[Formula: see text].

    Porter, D G / Forte, F / Granata, V / Cannavacciuolo, M / Fittipaldi, R / Cuoco, M / Bombardi, A / Vecchione, A

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 10957

    Abstract: Understanding and controlling the transition between antiferromagnetic states having different symmetry content with respect to time-inversion and space-group operations are fundamental challenges for the design of magnetic phases with topologically ... ...

    Abstract Understanding and controlling the transition between antiferromagnetic states having different symmetry content with respect to time-inversion and space-group operations are fundamental challenges for the design of magnetic phases with topologically nontrivial character. Here, we consider a paradigmatic antiferromagnetic oxide insulator, Ca[Formula: see text]RuO[Formula: see text], with symmetrically distinct magnetic ground states and unveil a novel path to guide the transition between them. The magnetic changeover results from structural and orbital reconstruction at the transition metal site that in turn arise as a consequence of substitutional doping. By means of resonant X-ray diffraction we track the evolution of the structural, magnetic, and orbital degrees of freedom for Mn doped Ca[Formula: see text]RuO[Formula: see text] to demonstrate the mechanisms which drive the antiferromagnetic transition. While our analysis focuses on a specific case of substitution, we show that any perturbation that can impact in a similar way on the crystal structure, by reconstructing the induced spin-orbital exchange, is able to drive the antiferromagnetic reorganization.
    Language English
    Publishing date 2022-06-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-14932-1
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  8. Article ; Online: Bone Marrow Niches and Tumour Cells: Lights and Shadows of a Mutual Relationship.

    Granata, Valentina / Crisafulli, Laura / Nastasi, Claudia / Ficara, Francesca / Sobacchi, Cristina

    Frontiers in immunology

    2022  Volume 13, Page(s) 884024

    Abstract: The bone marrow (BM) niche is the spatial structure within the intra-trabecular spaces of spongious bones and of the cavity of long bones where adult haematopoietic stem cells (HSCs) maintain their undifferentiated and cellular self-renewal state through ...

    Abstract The bone marrow (BM) niche is the spatial structure within the intra-trabecular spaces of spongious bones and of the cavity of long bones where adult haematopoietic stem cells (HSCs) maintain their undifferentiated and cellular self-renewal state through the intervention of vascular and nervous networks, metabolic pathways, transcriptional and epigenetic regulators, and humoral signals. Within the niche, HSCs interact with various cell types such as osteoblasts, endothelial cells, macrophages, and mesenchymal stromal cells (MSCs), which maintain HSCs in a quiescent state or sustain their proliferation, differentiation, and trafficking, depending on body needs. In physiological conditions, the BM niche permits the daily production of all the blood and immune cells and their admittance/ingress/progression into the bloodstream. However, disruption of this delicate microenvironment promotes the initiation and progression of malignancies such as those included in the spectrum of myeloid neoplasms, also favouring resistance to pharmacological therapies. Alterations in the MSC population and in the crosstalk with HSCs owing to tumour-derived factors contribute to the formation of a malignant niche. On the other hand, cells of the BM microenvironment cooperate in creating a unique milieu favouring metastasization of distant tumours into the bone. In this framework, the pro-tumorigenic role of MSCs is well-documented, and few evidence suggest also an anti-tumorigenic effect. Here we will review recent advances regarding the BM niche composition and functionality in normal and in malignant conditions, as well as the therapeutic implications of the interplay between its diverse cellular components and malignant cells.
    MeSH term(s) Bone Marrow/metabolism ; Endothelial Cells ; Hematopoietic Stem Cells/metabolism ; Mesenchymal Stem Cells/metabolism ; Stem Cell Niche
    Language English
    Publishing date 2022-05-06
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.884024
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  9. Article: Low-Power and Eco-Friendly Temperature Sensor Based on Gelatin Nanocomposite.

    Landi, Giovanni / Granata, Veronica / Germano, Roberto / Pagano, Sergio / Barone, Carlo

    Nanomaterials (Basel, Switzerland)

    2022  Volume 12, Issue 13

    Abstract: An environmentally-friendly temperature sensor has been fabricated by using a low-cost water-processable nanocomposite material based on gelatin and graphene. The temperature dependence of the electrochemical properties has been investigated by using ... ...

    Abstract An environmentally-friendly temperature sensor has been fabricated by using a low-cost water-processable nanocomposite material based on gelatin and graphene. The temperature dependence of the electrochemical properties has been investigated by using cyclic voltammetry, chronopotentiometry and impedance spectroscopy measurements. The simple symmetric device, composed of a sandwich structure between two metal foils and a printable graphene-gelatin blend, exhibits a dependence on the open-circuit voltage in a range between 260 and 310 K. Additionally, at subzero temperature, the device is able to detect the ice/frost formation. The thermally-induced phenomena occur at the electrode/gel interface with a bias current of a few tens of μA. The occurrence of dissociation reactions within the sensor causes limiting-current phenomena in the gelatin electrolyte. A detailed model describing the charge carrier accumulation, the faradaic charge transfer and diffusion processes within the device under the current-controlled has been proposed. In order to increase the cycle stability of the temperature sensor and reduce its voltage drift and offset of the output electrical signal, a driving circuit has been designed. The eco-friendly sensor shows a temperature sensitivity of about -19 mV/K, long-term stability, fast response and low-power consumption in the range of microwatts suitable for environmental monitoring for indoor applications.
    Language English
    Publishing date 2022-06-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano12132227
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Additional Considerations on Use of Abbreviated Liver MRI in Patients With Colorectal Liver Metastases.

    Granata, Vincenza / Fusco, Roberta / Petrillo, Antonella

    AJR. American journal of roentgenology

    2021  Volume 217, Issue 1, Page(s) W1

    MeSH term(s) Colorectal Neoplasms/diagnostic imaging ; Humans ; Liver ; Liver Neoplasms/diagnostic imaging ; Magnetic Resonance Imaging
    Language English
    Publishing date 2021-05-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.21.25652
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    In stock of ZB MED Cologne/Königswinter

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