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  1. Book ; Online: Reward- and aversion-related processing in the brain: translational evidence for separate and shared circuits

    Greenshaw, Andrew J. / Northoff, Georg / Hayes, Dave J.

    2016  

    Abstract: Affective brain circuits underpin our moods and emotions. Appetitive and aversive stimuli from our exteroceptive and interoceptive worlds play a key role in the activity of these circuits, but we still do not know precisely how to characterize these so- ... ...

    Abstract Affective brain circuits underpin our moods and emotions. Appetitive and aversive stimuli from our exteroceptive and interoceptive worlds play a key role in the activity of these circuits, but we still do not know precisely how to characterize these so-called reward-related and aversion-related systems. Moreover, we do we yet understand how they interact anatomically or functionally. The aim of the current project was to gather some translational evidence to help clarify the role of such circuits. A multi-dimensional problem in its own right, the book contains 14 works from authors exploring these questions at many levels, from the cellular to the cognitive-behavioral, and from both experimental and conceptual viewpoints. The editorial which introduces the book provides brief summaries of each perspective (Hayes, Northoff, Greenshaw, 2015). While questions of how to accurately define affect- and emotion-related concepts at the psychological level are far from answered, here we have attempted to provide some insight into the brain-based underpinnings of such processes. The near future will undoubtedly involve making new inroads and will require the joint efforts of behavioral, brain-based, and philosophical perspectives to do so
    Keywords Neurosciences. Biological psychiatry. Neuropsychiatry ; Science (General)
    Size 1 electronic resource (181 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020090559
    ISBN 9782889198368 ; 2889198367
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Shifting to Trauma-Informed Care in Inpatient Psychiatry: A Case Study of an Individual with Dissociative PTSD Undergoing EMDR Therapy.

    Winkler, Olga / Burback, Lisa / Greenshaw, Andrew J / Jin, Jonathan

    Case reports in psychiatry

    2023  Volume 2023, Page(s) 8161010

    Abstract: Caring for patients with personality disorders can be challenging due to risks associated with suicidal ideation, homicidal threats, splitting, and acting out with problematic behavior in psychiatric inpatient units. Limited resources on inpatient units ... ...

    Abstract Caring for patients with personality disorders can be challenging due to risks associated with suicidal ideation, homicidal threats, splitting, and acting out with problematic behavior in psychiatric inpatient units. Limited resources on inpatient units further add to the stress and burden on staff. This case summarizes how trauma-informed care was implemented in an inpatient setting to produce marked improvement in a patient's treatment outcomes as well as better staff engagement and satisfaction. This culture change in the approach to care was not an easy process, as effortful planning and resources were required for key elements such as ongoing coaching, education, and regular staff debriefings. This case report signals the need for service providers to enable health systems to examine rules and exceptions from a cultural perspective of considering equity, diversity, and inclusion (EDI)-to allow openness to rational exceptions, even if they are unconventional.
    Language English
    Publishing date 2023-01-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2629914-8
    ISSN 2090-6838 ; 2090-682X
    ISSN (online) 2090-6838
    ISSN 2090-682X
    DOI 10.1155/2023/8161010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Experimental psychopharmacology

    Greenshaw, Andrew J.

    (Contemporary neuroscience)

    1987  

    Author's details ed. by Andrew J. Greenshaw
    Series title Contemporary neuroscience
    Keywords Psychopharmacology ; Psychopharmakologie ; Forschungsmethode
    Subject Pharmakopsychopathologie ; Pharmakopsychiatrie ; Pharmakopsychologie ; Forschung
    Language English
    Size XIII, 494 S. : Ill., graph. Darst.
    Publisher Humana Pr
    Publishing place Clifton, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT003044713
    ISBN 0-89603-095-4 ; 978-0-89603-095-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1988 A 419 order for loan Magazin

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  4. Article: Editorial: Multi-site neuroimage analysis: Domain adaptation and batch effects.

    Yousefnezhad, Muhammad / Zhang, Daoqiang / Greenshaw, Andrew J / Greiner, Russell

    Frontiers in neuroinformatics

    2022  Volume 16, Page(s) 994463

    Language English
    Publishing date 2022-08-31
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2452979-5
    ISSN 1662-5196
    ISSN 1662-5196
    DOI 10.3389/fninf.2022.994463
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Commentary: Coercion in Psychiatry: Lessons Learned from Trauma-Informed Care.

    Jin, Jonathan / Burback, Lisa / Greenshaw, Andrew J / Winkler, Olga

    Canadian journal of psychiatry. Revue canadienne de psychiatrie

    2022  Volume 68, Issue 2, Page(s) 86–88

    MeSH term(s) Humans ; Coercion ; Psychiatry ; Mental Health Services ; Mental Disorders/therapy
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304227-3
    ISSN 1497-0015 ; 0008-4824 ; 0706-7437
    ISSN (online) 1497-0015
    ISSN 0008-4824 ; 0706-7437
    DOI 10.1177/07067437221125884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 110: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Sleep clinic service model with closed-loop management for insomnia.

    Liang, Sugai / Greenshaw, Andrew J / Li, Tao / Mao, Hongjing

    Asian journal of psychiatry

    2022  Volume 73, Page(s) 103158

    Abstract: Insomnia is a common medical condition associated with other psychological and physiological disorders, and may require long-term treatment and outpatient management. As such, it is critical that effective treatment and management is provided in clinical ...

    Abstract Insomnia is a common medical condition associated with other psychological and physiological disorders, and may require long-term treatment and outpatient management. As such, it is critical that effective treatment and management is provided in clinical practice. This study introduces an innovative outpatient service model for patients with insomnia, which includes providing medical care before, during and after diagnosis in public hospital clinics, completing prescribed treatments at home and return visits. It is a digital health-based, patient-centred, collaborative care model with closed-loop management. The proposed management strategy may help achieve a balance between the efficiency and the quality of outpatient medical care for insomnia.
    MeSH term(s) Ambulatory Care ; Humans ; Sleep ; Sleep Initiation and Maintenance Disorders/therapy ; Treatment Outcome
    Language English
    Publishing date 2022-05-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2022.103158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Randomized controlled trial investigating web-based, therapist delivered eye movement desensitization and reprocessing for adults with suicidal ideation.

    Burback, Lisa / Yap, Sidney / Purdon, Scot E / Abba-Aji, Adam / O'Shea, Katie / Brémault-Phillips, Suzette / Greenshaw, Andrew J / Winkler, Olga

    Frontiers in psychiatry

    2024  Volume 15, Page(s) 1361086

    Abstract: Introduction: Promising preliminary evidence suggests that EMDR may reduce suicidal ideation (SI) when used to treat Major Depressive Disorder, Posttraumatic Stress Disorder, and trauma symptoms in the context of acute mental health crises. EMDR has ... ...

    Abstract Introduction: Promising preliminary evidence suggests that EMDR may reduce suicidal ideation (SI) when used to treat Major Depressive Disorder, Posttraumatic Stress Disorder, and trauma symptoms in the context of acute mental health crises. EMDR has never been tested specifically for treating SI, and there is a lack of data regarding the safety and effectiveness of web-based, therapist-delivered EMDR in populations with known SI. The primary objective of this study was to investigate the impact of web-based, therapist-delivered EMDR, targeting experiences associated with suicidal thinking. Secondary objectives included examining the effect of EMDR treatment on symptoms of depression, anxiety, posttraumatic stress, emotional dysregulation, and dissociation, as well as safety and attrition.
    Methods: This randomized control trial (ClinicalTrials.gov ID number: NCT04181047) assigned adult outpatients reporting SI to either a web-based EMDR intervention or a treatment as usual (TAU) group. TAU included primary and mental health services available within the Canadian public health system. Participants in the EMDR group received up to 12 web-based EMDR desensitization sessions, delivered twice weekly during the COVID-19 pandemic (2021-2023). The Health Research Ethics Board at the University of Alberta approved the protocol prior to initiation of data collection for this study (protocol ID number: Pro00090989).
    Results: Forty-two adult outpatients received either EMDR (n=20) or TAU (n=22). Participants reported a high prevalence of early onset and chronic SI, and there was a high rate of psychiatric comorbidity. In the EMDR group, median SI, depression, anxiety, and posttraumatic symptom scale scores decreased from baseline to the four month follow-up. In the TAU group, only the median SI and posttraumatic symptom scale scores decreased from baseline to four month follow up. Although sample size precludes direct comparison, there were numerically fewer adverse events and fewer dropouts in the EMDR group relative to the TAU group.
    Conclusion: Study results provide promising preliminary evidence that web-based EMDR may be a viable delivery approach to address SI. In this complex population, a short treatment course was associated with reductions of SI and other symptoms across multiple diagnostic categories. Further investigation is warranted to verify and extend these results.
    Clinical trial registration: https://clinicaltrials.gov/study/NCT04181047?id=NCT04181047&rank=1, identifier NCT04181047.
    Language English
    Publishing date 2024-02-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2024.1361086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Prospective prediction of anxiety onset in the Canadian longitudinal study on aging (CLSA): A machine learning study.

    Li, Yutong / Song, Yipeng / Sui, Jie / Greiner, Russell / Li, Xin-Min / Greenshaw, Andrew J / Liu, Yang S / Cao, Bo

    Journal of affective disorders

    2024  Volume 357, Page(s) 148–155

    Abstract: Background: Anxiety disorders are among the most common mental health disorders in the middle aged and older population. Because older individuals are more likely to have multiple comorbidities or increased frailty, the impact of anxiety disorders on ... ...

    Abstract Background: Anxiety disorders are among the most common mental health disorders in the middle aged and older population. Because older individuals are more likely to have multiple comorbidities or increased frailty, the impact of anxiety disorders on their overall well-being is exacerbated. Early identification of anxiety disorders using machine learning (ML) can potentially mitigate the adverse consequences associated with these disorders.
    Methods: We applied ML to the data from the Canadian Longitudinal Study on Aging (CLSA) to predict the onset of anxiety disorders approximately three years in the future. We used Shapley value-based methods to determine the top factor for prediction. We also investigated whether anxiety onset can be predicted by baseline depression-related predictors alone.
    Results: Our model was able to predict anxiety onset accurately (Area under the Receiver Operating Characteristic Curve or AUC = 0.814 ± 0.016 (mean ± standard deviation), balanced accuracy = 0.741 ± 0.016, sensitivity = 0.743 ± 0.033, and specificity = 0.738 ± 0.010). The top predictive factors included prior depression or mood disorder diagnosis, high frailty, anxious personality, and low emotional stability. Depression and mood disorders are well known comorbidity of anxiety; however a prior depression or mood disorder diagnosis could not predict anxiety onset without other factors.
    Limitation: While our findings underscore the importance of a prior depression diagnosis in predicting anxiety, they also highlight that it alone is inadequate, signifying the necessity to incorporate additional predictors for improved prediction accuracy.
    Conclusion: Our study showcases promising prospects for using machine learning to develop personalized prediction models for anxiety onset in middle-aged and older adults using easy-to-access survey data.
    MeSH term(s) Humans ; Machine Learning ; Female ; Male ; Canada/epidemiology ; Longitudinal Studies ; Aged ; Anxiety Disorders/epidemiology ; Anxiety Disorders/diagnosis ; Anxiety Disorders/psychology ; Middle Aged ; Aging/psychology ; Aged, 80 and over ; Depression/epidemiology ; Depression/diagnosis ; Depression/psychology ; Comorbidity ; Frailty/diagnosis ; Frailty/epidemiology ; Prospective Studies ; Anxiety/epidemiology ; Anxiety/diagnosis ; Anxiety/psychology
    Language English
    Publishing date 2024-04-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2024.04.098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1485: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: The Impact of Supervised Consumption Services on Fentanyl-related Deaths: Lessons Learned from Alberta's Provincial Data.

    Marshall, Tyler / Abba-Aji, Adam / Tanguay, Robert / Greenshaw, Andrew J

    Canadian journal of psychiatry. Revue canadienne de psychiatrie

    2021  Volume 66, Issue 12, Page(s) 1096–1098

    MeSH term(s) Alberta/epidemiology ; Drug Overdose/epidemiology ; Drug Overdose/prevention & control ; Fentanyl/therapeutic use ; Harm Reduction ; Humans
    Chemical Substances Fentanyl (UF599785JZ)
    Language English
    Publishing date 2021-03-19
    Publishing country United States
    Document type Letter
    ZDB-ID 304227-3
    ISSN 1497-0015 ; 0008-4824 ; 0706-7437
    ISSN (online) 1497-0015
    ISSN 0008-4824 ; 0706-7437
    DOI 10.1177/0706743721999571
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Self research: A new pathway to precision psychiatry.

    Sui, Jie / Greenshaw, Andrew J / Macrae, C Neil / Cao, Bo

    Journal of affective disorders

    2021  Volume 293, Page(s) 276–278

    MeSH term(s) Humans ; Mental Disorders ; Psychiatry
    Language English
    Publishing date 2021-06-27
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2021.06.041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1485: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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