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  1. Article: Glucocorticoid-Responsive Transcription Factor Krüppel-Like Factor 9 Regulates

    Gans, Ian M / Grendler, Janelle / Babich, Remy / Jayasundara, Nishad / Coffman, James A

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 727037

    Abstract: Krüppel-like factor 9 (Klf9) is a feedforward regulator of glucocorticoid receptor (GR) signaling. Here we show that in ... ...

    Abstract Krüppel-like factor 9 (Klf9) is a feedforward regulator of glucocorticoid receptor (GR) signaling. Here we show that in zebrafish
    Language English
    Publishing date 2021-10-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.727037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Wound-induced polyploidization is driven by Myc and supports tissue repair in the presence of DNA damage.

    Grendler, Janelle / Lowgren, Sara / Mills, Monique / Losick, Vicki P

    Development (Cambridge, England)

    2019  Volume 146, Issue 15

    Abstract: Tissue repair usually requires either polyploid cell growth or cell division, but the molecular mechanism promoting polyploidy and limiting cell division remains poorly understood. Here, we find that injury to the ... ...

    Abstract Tissue repair usually requires either polyploid cell growth or cell division, but the molecular mechanism promoting polyploidy and limiting cell division remains poorly understood. Here, we find that injury to the adult
    MeSH term(s) Animals ; Animals, Genetically Modified ; Cdh1 Proteins/metabolism ; Cell Cycle Proteins/metabolism ; DNA Damage/genetics ; DNA-Binding Proteins/genetics ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/physiology ; Epithelial Cells/metabolism ; Epithelium/injuries ; Gene Expression Regulation/genetics ; Mitosis/genetics ; Mitosis/physiology ; Polyploidy ; Protein Tyrosine Phosphatases/metabolism ; Transcription Factors/genetics ; Wound Healing/genetics ; Wound Healing/physiology
    Chemical Substances Cdh1 Proteins ; Cell Cycle Proteins ; DNA-Binding Proteins ; Drosophila Proteins ; E2f1 protein, Drosophila ; Myc protein, Drosophila ; Transcription Factors ; fzr protein, Drosophila ; Protein Tyrosine Phosphatases (EC 3.1.3.48) ; stg protein, Drosophila (EC 3.1.3.48)
    Language English
    Publishing date 2019-08-02
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 90607-4
    ISSN 1477-9129 ; 0950-1991
    ISSN (online) 1477-9129
    ISSN 0950-1991
    DOI 10.1242/dev.173005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Loss of Krüppel-like factor 9 deregulates both physiological gene expression and development.

    Drepanos, Laura / Gans, Ian M / Grendler, Janelle / Guitar, Sophia / Fuqua, J Heath / Maki, Nathaniel J / Tilden, Andrea R / Graber, Joel H / Coffman, James A

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 12239

    Abstract: Krüppel-like factor 9 (Klf9) is a ubiquitously expressed transcription factor that is a feedforward regulator of multiple stress-responsive and endocrine signaling pathways. We previously described how loss of Klf9 function affects the transcriptome of ... ...

    Abstract Krüppel-like factor 9 (Klf9) is a ubiquitously expressed transcription factor that is a feedforward regulator of multiple stress-responsive and endocrine signaling pathways. We previously described how loss of Klf9 function affects the transcriptome of zebrafish larvae sampled at a single time point 5 days post-fertilization (dpf). However, klf9 expression oscillates diurnally, and the sampled time point corresponded to its expression nadir. To determine if the transcriptomic effects of the klf9
    MeSH term(s) Animals ; Zebrafish/genetics ; Zebrafish/metabolism ; Kruppel-Like Transcription Factors/metabolism ; Gene Expression Regulation ; Gene Expression ; RNA, Messenger/metabolism
    Chemical Substances Kruppel-Like Transcription Factors ; RNA, Messenger
    Language English
    Publishing date 2023-07-28
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-39453-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Analysis of Gene Expression in an Inbred Line of Soft-Shell Clams (

    Wilson, John J / Grendler, Janelle / Dunlap-Smith, Azaline / Beal, Brian F / Page, Shallee T

    International journal of genomics

    2016  Volume 2016, Page(s) 6720947

    Abstract: ... Mya ... ...

    Abstract Mya arenaria
    Language English
    Publishing date 2016-10-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2711883-6
    ISSN 2314-4378 ; 2314-436X
    ISSN (online) 2314-4378
    ISSN 2314-436X
    DOI 10.1155/2016/6720947
    Database MEDical Literature Analysis and Retrieval System OnLINE

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