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  1. Book ; Thesis: Retrospektive Analyse der prognostischen Bedeutung des Körperfettanteils gemessen in der Ganzkörper-Computertomographie bei Patienten mit symptomatischem Multiplen Myelom und Korrelation mit klinischen und demographischen Parametern

    Groß, Jonathan P.

    2020  

    Institution Universität Heidelberg
    Author's details vorgelegt von Jonathan Philipp Groß aus Berlin
    Language German
    Size 85 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2020
    HBZ-ID HT020696559
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 E 102 order for loan Magazin

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  2. Article ; Online: Designing Codes around Interactions: The Case of a Spin.

    Gross, Jonathan A

    Physical review letters

    2021  Volume 127, Issue 1, Page(s) 10504

    Abstract: I present a new approach for designing quantum error-correcting codes guaranteeing a physically natural implementation of Clifford operations. Inspired by the scheme put forward by Gottesman, Kitaev, and Preskill for encoding a qubit in an oscillator in ... ...

    Abstract I present a new approach for designing quantum error-correcting codes guaranteeing a physically natural implementation of Clifford operations. Inspired by the scheme put forward by Gottesman, Kitaev, and Preskill for encoding a qubit in an oscillator in which Clifford operations may be performed via Gaussian unitaries, this approach yields new schemes for encoding a qubit in a large spin in which single-qubit Clifford operations may be performed via spatial rotations. I construct all possible examples of such codes, provide universal-gate-set implementations using quadratic angular-momentum Hamiltonians, and derive criteria for when these codes exactly correct physically relevant errors.
    Language English
    Publishing date 2021-07-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.127.010504
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  3. Article ; Online: All Specialties in Radiology Must Address the Climate Crisis.

    Gross, Jonathan S / Thiel, Cassandra L

    Radiology

    2022  Volume 303, Issue 2, Page(s) E24

    MeSH term(s) Humans ; Radiography ; Radiology
    Language English
    Publishing date 2022-02-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.211856
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Covid-19 and the politics of hope: A comparative analysis of Greek and Ecuadorian letters from a desired post-pandemic future.

    Gross, Jonathan / Davids, Tine / Sools, Anneke / Saghai, Yashar

    Futures

    2023  Volume 149, Page(s) 103115

    Abstract: Covid-19 forced changes in everyday life upon large sections of the world's population, with lockdowns and social distancing measures effecting conditions of work and leisure for billions of people. In this context our research created a space in which ... ...

    Abstract Covid-19 forced changes in everyday life upon large sections of the world's population, with lockdowns and social distancing measures effecting conditions of work and leisure for billions of people. In this context our research created a space in which people living in countries in Europe, North and South America, Asia, and Africa were invited to imagine what the future could look like - beyond the pandemic - by writing a
    Language English
    Publishing date 2023-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2013109-4
    ISSN 0016-3287
    ISSN 0016-3287
    DOI 10.1016/j.futures.2023.103115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reversible oxidative dimerization of 4-thiouridines in tRNA isolates.

    Bessler, Larissa / Groß, Jonathan / Kampf, Christopher J / Opatz, Till / Helm, Mark

    RSC chemical biology

    2024  Volume 5, Issue 3, Page(s) 216–224

    Abstract: The occurrence of non-canonical nucleoside structures in RNA of biological or synthetic origin has encountered several recent boosts in attention, namely in the context of RNA modifications, and with an eye to RNA vaccines. New nucleoside structures ... ...

    Abstract The occurrence of non-canonical nucleoside structures in RNA of biological or synthetic origin has encountered several recent boosts in attention, namely in the context of RNA modifications, and with an eye to RNA vaccines. New nucleoside structures introduce added functionality and function into biopolymers that are otherwise rather homogenous in their chemical structure. Here, we report the discovery of a presumed RNA modification that was identified by combination of liquid chromatography-tandem mass spectrometry (LC-MS/MS) with stable isotope labelling as a dimer of the known RNA modification 4-thiouridine (s
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article
    ISSN 2633-0679
    ISSN (online) 2633-0679
    DOI 10.1039/d3cb00221g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: An In Vitro Study of Local Oxygen Therapy as Adjunctive Antimicrobial Therapeutic Option for Patients with Periodontitis.

    Müller-Heupt, Lena Katharina / Eckelt, Anja / Eckelt, John / Groß, Jonathan / Opatz, Till / Kommerein, Nadine

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 6

    Abstract: Periodontitis is a common global disease caused by bacterial dysbiosis leading to tissue destruction, and it is strongly associated with anaerobic bacterial colonization. Therapeutic strategies such as oxygen therapy have been developed to positively ... ...

    Abstract Periodontitis is a common global disease caused by bacterial dysbiosis leading to tissue destruction, and it is strongly associated with anaerobic bacterial colonization. Therapeutic strategies such as oxygen therapy have been developed to positively influence the dysbiotic microbiota, and the use of oxygen-releasing substances may offer an added benefit of avoiding systemic effects commonly associated with antibiotics taken orally or hyperbaric oxygen therapy. Therefore, the oxygen release of calcium peroxide (CaO
    Language English
    Publishing date 2023-05-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12060990
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Complementary mechanochemical and biphasic approaches for the synthesis of organic thiocyanates using hexacyanoferrates as non-toxic cyanide sources.

    Grundke, Caroline / Groß, Jonathan / Vierengel, Nina / Sirleaf, Jason / Schmitz, Matthias / Krieger, Leonie / Opatz, Till

    Organic & biomolecular chemistry

    2023  Volume 21, Issue 3, Page(s) 644–650

    Abstract: Herein, we describe two complementary approaches towards various organic thiocyanates that are affordable, reliable and follow the principles of sustainable chemistry, starting from commercially available thiols or disulfides. Additionally, the ... ...

    Abstract Herein, we describe two complementary approaches towards various organic thiocyanates that are affordable, reliable and follow the principles of sustainable chemistry, starting from commercially available thiols or disulfides. Additionally, the application of this mild method to the first total synthesis of psammaplin B is demonstrated. Non-toxic and inexpensive ferricyanide is used as the cyanide source, which can be activated either in a mechanochemical, solvent-free approach, or in a biphasic solvent system allowing easier work-up. A total of 27 examples is demonstrated, with up to quantitative yields.
    MeSH term(s) Thiocyanates ; Ferrocyanides ; Cyanides ; Disulfides
    Chemical Substances hexacyanoferrate II (FLX0VIC39Y) ; Thiocyanates ; Ferrocyanides ; Cyanides ; Disulfides ; ferrocyn
    Language English
    Publishing date 2023-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d2ob02216h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Total Synthesis and Biological Evaluation of the Anti-Inflammatory (13

    Seipp, Kevin / Groß, Jonathan / Kiefer, Anna Maria / Erkel, Gerhard / Opatz, Till

    Journal of natural products

    2023  Volume 86, Issue 4, Page(s) 924–938

    Abstract: The first total synthesis of the natural product ( ... ...

    Abstract The first total synthesis of the natural product (13
    MeSH term(s) Anti-Inflammatory Agents/pharmacology ; Isomerism ; Molecular Structure ; Stereoisomerism
    Chemical Substances Anti-Inflammatory Agents ; (13R,14S,15R)-13-hydroxy-14-deoxyoxacyclododecindione
    Language English
    Publishing date 2023-03-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.2c01145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  9. Article ; Online: Climate Change and Radiology: Impetus for Change and a Toolkit for Action.

    Brown, Maura / Schoen, Julia Hyde / Gross, Jonathan / Omary, Reed A / Hanneman, Kate

    Radiology

    2023  Volume 307, Issue 4, Page(s) e230229

    Abstract: This special report discusses the importance of climate change for health care and radiology. The impact of climate change on human health and health equity, the contribution of health care and medical imaging to the climate crisis, and the impetus for ... ...

    Abstract This special report discusses the importance of climate change for health care and radiology. The impact of climate change on human health and health equity, the contribution of health care and medical imaging to the climate crisis, and the impetus for change within radiology to create a more sustainable future are covered. The authors focus on actions and opportunities to address climate change in our role as radiologists. A toolkit highlights actions we can take toward a more sustainable future, linking each action with the expected impact and outcome. This toolkit includes a hierarchy of actions from first steps to advocating for system-level change. This includes actions we can take in our daily lives, in radiology departments and professional organizations, and in our relationships with vendors and industry partners. As radiologists, we are adept at managing rapid technological change, which makes us ideally suited to lead these initiatives. Alignment of incentives and synergies with health systems are highlighted given that many of the proposed strategies also result in cost savings.
    MeSH term(s) Humans ; Climate Change ; Radiology/methods ; Radiography ; Delivery of Health Care ; Radiologists
    Language English
    Publishing date 2023-04-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.230229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Sesquiterpene Lactones from Vernonia tufnelliae: Structural Characterization and Biological Evaluation

    Bitchagno, Gabin Thierry M. / Schüffler, Anja / Gross, Jonathan / Krumb, Matthias / Tane, Pierre / Opatz, Till

    Journal of natural products. 2022 June 15, v. 85, no. 7

    2022  

    Abstract: The genus Vernonia is an extremely rich source of biologically active sesquiterpene lactones. The present report describes the spectroscopic structure elucidation and the cytotoxic and antimicrobial properties of five hitherto unknown germacranolide-like ...

    Abstract The genus Vernonia is an extremely rich source of biologically active sesquiterpene lactones. The present report describes the spectroscopic structure elucidation and the cytotoxic and antimicrobial properties of five hitherto unknown germacranolide-like sesquiterpenoids and several known compounds. These new derivatives include a compound (1) with an unprecedented 10/5/5/6 tetracyclic framework featuring a hexahydro-1H,3H,7H-furo[3′,4′:3,4]furo[3,2-c]pyridin-1-one core resulting from an intramolecular cyclization cascade involving a methacrylate substituent and a low molecular weight amine. Furthermore, an elemane–germacranolide hybrid (2) and three amino acid-derived lactones (3–5) were characterized. A plausible biosynthetic pathway to the key alkaloid is presented, while shielding tensor calculations using DFT in combination with the DP4+ method were applied to elucidate its stereostructure. The newly characterized compounds along with ten known sesquiterpene lactones and phenolic compounds have been isolated from Vernonia tufnelliae, a medicinal plant from the western region of Cameroon. Their structures were consistent with spectroscopic and spectrometric data recorded. The present report is the first investigation of the chemistry and biology of V. tufnelliae.
    Keywords Vernonia ; alkaloids ; biochemical pathways ; biological assessment ; cyclization reactions ; cytotoxicity ; hybrids ; medicinal plants ; molecular weight ; sesquiterpenoid lactones ; spectroscopy ; Cameroon
    Language English
    Dates of publication 2022-0615
    Size p. 1681-1690.
    Publishing place American Chemical Society and American Society of Pharmacognosy
    Document type Article
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.2c00055
    Database NAL-Catalogue (AGRICOLA)

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