Article ; Online: pgMAP: a pipeline to enable guide RNA read mapping from dual-targeting CRISPR screens.
ArXiv
2023
Abstract: We developed pgMAP, an analysis pipeline to map gRNA sequencing reads from dual-targeting CRISPR screens. pgMAP output includes a dual gRNA read counts table and quality control metrics including the proportion of correctly-paired reads and CRISPR ... ...
| Abstract | We developed pgMAP, an analysis pipeline to map gRNA sequencing reads from dual-targeting CRISPR screens. pgMAP output includes a dual gRNA read counts table and quality control metrics including the proportion of correctly-paired reads and CRISPR library sequencing coverage across all time points and samples. pgMAP is implemented using Snakemake and is available open-source under the MIT license at https://github.com/fredhutch/pgmap_pipeline. |
|---|---|
| Language | English |
| Publishing date | 2023-06-01 |
| Publishing country | United States |
| Document type | Preprint |
| ISSN | 2331-8422 |
| ISSN (online) | 2331-8422 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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