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  1. Book: Connective tissue disorders

    Gordon, Caroline / Gross, Wolfgang L.

    (An atlas of investigation and management)

    2011  

    Author's details Caroline Gordon ; Wolfgang L. Gross
    Series title An atlas of investigation and management
    Language English
    Size X, 122 S. : zahlr. Ill.
    Publisher Clinical Publ
    Publishing place Oxford u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT016686806
    ISBN 978-1-84692-074-5 ; 1-84692-074-4 ; 9781846926341 ; 1846926343
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 4695 order for loan Magazin

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  2. Book ; Conference proceedings: ANCA associated vasculitides

    Gross, Wolfgang L.

    immunological and clinical aspects ; [proceedings of the Fourth International Workshop on ANCA (Antineutrophil Cytoplasmic Antibodies) and the Second International Colloquium on Wegener's Granulomatosis and Vasculitic Disorders, held May 28 - 30, 1992, in Lübeck, Germany]

    (Advances in experimental medicine and biology ; 336)

    1993  

    Title variant ANCA-associated
    Event/congress International Colloquium on Wegener's Granulomatosis and Vasculitic Disorders (2, 1992, Lübeck) ; International Workshop on ANCA (4, 1992, Lübeck)
    Author's details ed. by Wolfgang L. Gross
    Series title Advances in experimental medicine and biology ; 336
    Collection
    Keywords Vasculitis / congresses ; Autoantibodies / congresses ; Wegener's Granulomatosis / congresses ; Vaskulitis ; Granulomatose mit Polyangiitis
    Subject Morbus Wegener ; Wegenersche Granulomatose ; Granulomatosis Wegener ; Wegener Granulomatose ; Wegener Granulomatose Syndrom ; Wegener-Klinger Granulomatose ; Klinger-Wegener-Granulomatose ; GPA ; Granuloma gangraenescens ; Gefäßentzündung ; Vasculitis ; Vascularitis ; Vaskulitiden ; Angiitis ; Systemische Vasculitis ; Vasculitides ; Angiitides
    Language English
    Size XIX, 552 S. : Ill., graph. Darst.
    Publisher Plenum Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT006133742
    ISBN 0-306-44573-5 ; 978-0-306-44573-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3192 -336- verfügbar in Königswinter Königswinter

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  3. Book: Therapie der Immunvaskulitiden

    Gross, Wolfgang L.

    (UNI-MED science)

    2000  

    Author's details [Wolfgang L. Gross]
    Series title UNI-MED science
    Keywords Vaskulitis ; Immunkrankheit ; Therapie
    Subject Medizinische Behandlung ; Behandlung ; Krankenbehandlung ; Immunopathie ; Immunologische Krankheit ; Immunologische Erkrankung ; Gefäßentzündung ; Vasculitis ; Vascularitis ; Vaskulitiden ; Angiitis ; Systemische Vasculitis ; Vasculitides ; Angiitides
    Language German
    Size 136 S. : Ill., graph. Darst.
    Edition 1. Aufl.
    Publisher UNI-MED-Verl
    Publishing place Bremen u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT013017071
    ISBN 3-89599-512-6 ; 978-3-89599-512-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 A 2292 order for loan Magazin

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  4. Book: Systemic lupus erythematosus

    Gordon, Caroline / Gross, Wolfgang L

    (Visual guide for clinicians)

    2012  

    Author's details [edited by] Caroline Gordon, Wolfgang L. Gross
    Series title Visual guide for clinicians
    MeSH term(s) Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/therapy ; Sjogren's Syndrome/diagnosis ; Sjogren's Syndrome/therapy
    Language English
    Size viii, 56 p. :, ill., ;, 31 cm.
    Publisher Clinical Pub
    Publishing place Oxford
    Document type Book
    Note Content first published in 2011 as part of Connective tissue diseases : an atlas of investigation and management (Oxford : Clinical Publishing).
    ISBN 9781846921001 ; 1846921007 ; 9781846926433 ; 1846926432
    Database Catalogue of the US National Library of Medicine (NLM)

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  5. Article ; Online: Treatment of ANCA-associated vasculitides (AAV).

    Holle, Julia U / Gross, Wolfgang L

    Autoimmunity reviews

    2013  Volume 12, Issue 4, Page(s) 483–486

    Abstract: Treatment of AAV follows the principle of a combined remission induction and maintenance strategy and is adapted in a stage and activity-adapted fashion. So far the combination therapy of glucocorticoids and conventional immunosuppressive drugs has ... ...

    Abstract Treatment of AAV follows the principle of a combined remission induction and maintenance strategy and is adapted in a stage and activity-adapted fashion. So far the combination therapy of glucocorticoids and conventional immunosuppressive drugs has mainly been used to control disease. This approach has led to a significant improvement in outcome in spite of persistently high early mortality rates of nearly 11% within the first year. Besides conventional treatment, biologics have emerged as a new treatment option. The paper summarizes the current evidence for the use of conventional therapy and biologics in AAV.
    MeSH term(s) Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/drug therapy ; Churg-Strauss Syndrome/drug therapy ; Granulomatosis with Polyangiitis/drug therapy ; Humans ; Immunosuppressive Agents/therapeutic use ; Microscopic Polyangiitis/drug therapy ; Recurrence ; Remission Induction
    Chemical Substances Immunosuppressive Agents
    Language English
    Publishing date 2013-02
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2144145-5
    ISSN 1873-0183 ; 1568-9972
    ISSN (online) 1873-0183
    ISSN 1568-9972
    DOI 10.1016/j.autrev.2012.08.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5913: Show issues Location:
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  6. Article ; Online: Current understanding of the pathogenesis of granulomatosis with polyangiitis (Wegener's).

    Csernok, Elena / Gross, Wolfgang L

    Expert review of clinical immunology

    2013  Volume 9, Issue 7, Page(s) 641–648

    Abstract: Granulomatosis with polyangiitis (Wegener's) (GPA) is a multisystem disease of unknown etiology, characterized by granulomata of the respiratory tract and systemic necrotizing vasculitis. Antineutrophil cytoplasmic antibodies (ANCA) with specificity for ... ...

    Abstract Granulomatosis with polyangiitis (Wegener's) (GPA) is a multisystem disease of unknown etiology, characterized by granulomata of the respiratory tract and systemic necrotizing vasculitis. Antineutrophil cytoplasmic antibodies (ANCA) with specificity for proteinase 3 (PR3) are a defining feature of this disease. GPA usually starts as a granulomatous disease of the respiratory tract and, in the majority of patients, progresses to systemic disease with PR3-ANCA-associated vasculitis. Today, epidemiological evidence indicates that GPA develops as a result of complex gene-environment interactions. The nature of these risk factors and pathogenic mechanisms involved, however, are only just beginning to be understood. Clinical data and in vitro experimental results point to the pathogenic pathways involved in tissue lesion development, in which ANCA, cellular immunity, neutrophils extracellular traps, fibroblasts, vascular endothelial cells and inflammatory mediators play a major role. Today, the pathophysiological significance of PR3-ANCA is still unclear and the pathogenic pathways leading to granuloma formation are not explained. New data unexpectedly suggest that the destruction of nasal cartilage in GPA is mainly mediated by fibroblasts that can be blocked by corticosteroids.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Antibodies, Antineutrophil Cytoplasmic/metabolism ; Autoantigens/immunology ; Endothelium, Vascular/immunology ; Gene-Environment Interaction ; Granuloma/immunology ; Granulomatosis with Polyangiitis/drug therapy ; Granulomatosis with Polyangiitis/immunology ; Humans ; Immunity, Cellular ; Microscopic Polyangiitis/drug therapy ; Microscopic Polyangiitis/immunology ; Myeloblastin/immunology ; Nasal Cartilages/drug effects ; Nasal Cartilages/pathology ; Respiratory System/pathology
    Chemical Substances Adrenal Cortex Hormones ; Antibodies, Antineutrophil Cytoplasmic ; Autoantigens ; Myeloblastin (EC 3.4.21.76)
    Language English
    Publishing date 2013-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1586/1744666X.2013.811052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6661: Show issues Location:
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  7. Book: Connective tissue diseases

    Gordon, Caroline / Gross, Wolfgang L

    an atlas of investigation and management

    2011  

    Author's details [editors], Caroline Gordon, Wolfgang L. Gross
    MeSH term(s) Connective Tissue Diseases ; Autoimmune Diseases
    Language English
    Size x, 122 p. :, ill.
    Publisher Clinical Pub
    Publishing place Oxford
    Document type Book
    ISBN 9781846920745 ; 9781846926341 ; 1846920744 ; 1846926343
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article: Zeitschrift für Rheumatologie in neuer Gestalt. Was kommt--was bleibt?

    Gross, Wolfgang L

    Zeitschrift fur Rheumatologie

    2006  Volume 65, Issue 1, Page(s) 5

    Title translation Publications for rheumatology in new forms. What will come--what will remain?.
    MeSH term(s) Germany ; Information Dissemination/methods ; Information Storage and Retrieval/methods ; Information Storage and Retrieval/trends ; Internet ; Online Systems ; Periodicals as Topic/trends ; Publishing/trends ; Rheumatology/trends
    Language German
    Publishing date 2006-06-19
    Publishing country Germany
    Document type Editorial
    ZDB-ID 124985-x
    ISSN 1435-1250 ; 0340-1855 ; 0301-6382
    ISSN (online) 1435-1250
    ISSN 0340-1855 ; 0301-6382
    DOI 10.1007/s00393-006-0043-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.128: Show issues Location:
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  9. Article ; Online: Vasculitis in 2011: the renaissance of granulomatous inflammation in AAV.

    Gadola, Stephan D / Gross, Wolfgang L

    Nature reviews. Rheumatology

    2012  Volume 8, Issue 2, Page(s) 74–76

    Abstract: In 2011, the year that subtypes of ANCA-associated vasculitis (AAV) were officially renamed according to key pathological characteristics, important progress was made not only in differentiating these subtypes, but also in understanding—and treating— ... ...

    Abstract In 2011, the year that subtypes of ANCA-associated vasculitis (AAV) were officially renamed according to key pathological characteristics, important progress was made not only in differentiating these subtypes, but also in understanding—and treating—their eponymous manifestations.
    MeSH term(s) Antibodies, Antineutrophil Cytoplasmic/blood ; Antibodies, Monoclonal, Murine-Derived/therapeutic use ; Granulomatosis with Polyangiitis/blood ; Granulomatosis with Polyangiitis/classification ; Granulomatosis with Polyangiitis/diagnosis ; Granulomatosis with Polyangiitis/drug therapy ; Humans ; Immunologic Factors/therapeutic use ; Neural Networks, Computer ; Rituximab ; Terminology as Topic ; Vasculitis/blood ; Vasculitis/classification ; Vasculitis/diagnosis ; Vasculitis/drug therapy
    Chemical Substances Antibodies, Antineutrophil Cytoplasmic ; Antibodies, Monoclonal, Murine-Derived ; Immunologic Factors ; Rituximab (4F4X42SYQ6)
    Language English
    Publishing date 2012-01-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2491532-4
    ISSN 1759-4804 ; 1759-4790
    ISSN (online) 1759-4804
    ISSN 1759-4790
    DOI 10.1038/nrrheum.2011.218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6338: Show issues Location:
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  10. Article ; Online: Pathogenesis of anti-neutrophil cytoplasmic antibody-associated vasculitis: challenges and solutions 2014.

    Schönermarck, Ulf / Csernok, Elena / Gross, Wolfgang L

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2015  Volume 30 Suppl 1, Page(s) i46–52

    Abstract: Anti-neutrophil cytoplasmic autoantibodies (ANCA) with specificity for proteinase 3 (PR3-ANCA) or myeloperoxidase (MPO-ANCA) are a defining feature of ANCA-associated vasculitides (AAV). They play a pivotal role in disease pathophysiology and have ... ...

    Abstract Anti-neutrophil cytoplasmic autoantibodies (ANCA) with specificity for proteinase 3 (PR3-ANCA) or myeloperoxidase (MPO-ANCA) are a defining feature of ANCA-associated vasculitides (AAV). They play a pivotal role in disease pathophysiology and have strongly improved early diagnosis and treatment of these infrequent, but potentially fatal diseases. Neutrophils and their products are major players in initiating the autoimmune response and tissue destruction in vasculitic as well as granulomatous inflammation. This review highlights recent findings on old and novel players (ANCA, neutrophils, neutrophil extracellular traps, fibroblasts, immune cells and complement) and puts them into context with the current understanding of disease mechanisms in AAV.
    MeSH term(s) Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/etiology ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/immunology ; Autoimmunity/immunology ; Complement System Proteins/immunology ; Humans ; Neutrophils/immunology
    Chemical Substances Complement System Proteins (9007-36-7)
    Language English
    Publishing date 2015-04
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfu398
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 329: Show issues

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