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  1. Article: Thermal and Optical Properties of the Sunspace Casing as Factors Influencing Temperature Rise in Greenhouse Systems.

    Grudzińska, Magdalena

    Materials (Basel, Switzerland)

    2021  Volume 14, Issue 23

    Abstract: In sunspaces, there is an observable temperature rise above the external air temperature, caused by solar gains and the buffering effect of their enclosure. In addition, their external partitions form a barrier preventing the direct influence of the ... ...

    Abstract In sunspaces, there is an observable temperature rise above the external air temperature, caused by solar gains and the buffering effect of their enclosure. In addition, their external partitions form a barrier preventing the direct influence of the external environment and delaying the natural deterioration of elevation surface. In the paper, the temperature rise in a glazed balcony attached to a typical flat in a multifamily building, together with the energy demand in the living zone, were assessed with the use of dynamic computer simulations. Ten variants of the sunspace casing were analysed, with different thermal and solar energy transmittance of the glazing (which is a novel subject in the research area). This enabled us to evaluate average values of the temperature reduction factor during the year and to choose the most efficient variant of the sunspace external partitions. It turned out to be an insulated, double-glazed casing with a spectrally selective coating (type O 21), combining high insulative properties with high solar transmittance. These features allowed the temperature in the sunspace to rise by almost 10°C (compared with the external air) and lower total energy demand in the flat by 33% (compared with a flat with an open balcony).
    Language English
    Publishing date 2021-12-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma14237411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chickpea Sprouts as a Potential Dietary Support in Different Prostate Disorders-A Preliminary In Vitro Study.

    Galanty, Agnieszka / Prochownik, Ewelina / Grudzińska, Marta / Paśko, Paweł

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 5

    Abstract: Background: Prostate cancer (PC) and benign prostatic hyperplasia (BPH) are common health problems in the aging male population. Due to the unexplored and unconfirmed impact of food containing isoflavones, like sprouts, on the development of the ... ...

    Abstract Background: Prostate cancer (PC) and benign prostatic hyperplasia (BPH) are common health problems in the aging male population. Due to the unexplored and unconfirmed impact of food containing isoflavones, like sprouts, on the development of the management of BPH and prostate cancer, we decided to extend the knowledge in this area.
    Results: We have demonstrated for the first time that chickpea sprouts may play an important role in the chemoprevention of prostate disorders. However, attention should be paid to the isoflavone content in the sprouts, as in our study, chickpea sprouts with a moderate concentration of the compounds, harvested in natural light conditions (CA10L) and blue LED light (CA7B), showed the best scores in terms of their potential towards prostate disorders.
    Methods: Chickpea seeds were grown in LED chambers. The methanol extracts from sprouts were quantitatively defined using the HPLC system. Experiments such as the determination of PSA, 5-α-reductase, and dihydrotestosterone were performed on PNT2 and LNCaP cells. For anti-inflammatory assays (determination of NO, IL-6, and TNF-alpha release), murine RAW264.7 macrophages were used.
    Conclusions: The role of legume products as a diet element should be deeply evaluated for the development of future dietary recommendations for prostate cancer and BPH prevention.
    MeSH term(s) Male ; Humans ; Animals ; Mice ; Cicer/chemistry ; Prostatic Hyperplasia ; Prostate ; Prostatic Neoplasms ; Isoflavones/chemistry ; Diet
    Chemical Substances Isoflavones
    Language English
    Publishing date 2024-02-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29051044
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  3. Article ; Online: Do Brassica Vegetables Affect Thyroid Function?-A Comprehensive Systematic Review.

    Galanty, Agnieszka / Grudzińska, Marta / Paździora, Wojciech / Służały, Piotr / Paśko, Paweł

    International journal of molecular sciences

    2024  Volume 25, Issue 7

    Abstract: Brassica vegetables are widely consumed all over the world, especially in North America, Asia, and Europe. They are a rich source of sulfur compounds, such as glucosinolates (GLSs) and isothiocyanates (ITCs), which provide health benefits but are also ... ...

    Abstract Brassica vegetables are widely consumed all over the world, especially in North America, Asia, and Europe. They are a rich source of sulfur compounds, such as glucosinolates (GLSs) and isothiocyanates (ITCs), which provide health benefits but are also suspected of having a goitrogenic effect. Adhering to PRISMA guidelines, we conducted a systematic review to assess the impact of dietary interventions on thyroid function, in terms of the potential risk for people with thyroid dysfunctions. We analyzed the results of 123 articles of in vitro, animal, and human studies, describing the impact of brassica plants and extracts on thyroid mass and histology, blood levels of TSH, T3, T4, iodine uptake, and the effect on thyroid cancer cells. We also presented the mechanisms of the goitrogenic potential of GLSs and ITCs, the limitations of the studies included, as well as further research directions. The vast majority of the results cast doubt on previous assumptions claiming that brassica plants have antithyroid effects in humans. Instead, they indicate that including brassica vegetables in the daily diet, particularly when accompanied by adequate iodine intake, poses no adverse effects on thyroid function.
    MeSH term(s) Animals ; Humans ; Vegetables ; Brassica ; Isothiocyanates ; Glucosinolates ; Goiter ; Iodine
    Chemical Substances Isothiocyanates ; Glucosinolates ; Iodine (9679TC07X4)
    Language English
    Publishing date 2024-04-03
    Publishing country Switzerland
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25073988
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  4. Article ; Online: Can edible sprouts be the element of effective chemopreventive strategy? - A systematic review of in vitro and in vivo study

    Grudzińska, Marta / Galanty, Agnieszka / Paśko, Paweł

    Trends in Food Science & Technology. 2023 Sept., v. 139 p.104130-

    2023  

    Abstract: Cancer is a disease that seriously and increasingly threatens human health and life, affecting various organs such as: breast, lung, colon and rectum, prostate or stomach. Because of that it is so important to find appropriate chemopreventive agents that ...

    Abstract Cancer is a disease that seriously and increasingly threatens human health and life, affecting various organs such as: breast, lung, colon and rectum, prostate or stomach. Because of that it is so important to find appropriate chemopreventive agents that can prevent the development of cancer in humans. One of such methods may be a healthy diet rich in vegetables and fruits, including sprouts, which have recently gained popularity due to their health-promoting properties and easy process of cultivation. The purpose of the following systematic review is to collect the results of all so far published studies on the chemopreventive potential of sprouts of various edible plants, in order to select the most promising species for further research. This paper focused on the impact of sprouts extracts on cancer cells in vitro, as determined by the inhibition of tumor cell proliferation, growth and viability, or apoptosis stimulation, with special interest put on the results of the in vivo and human studies. The influence of different cultivation conditions and biofortification with selenium and probiotics on the activity of sprouts was assessed. Attempts were also made to indicate the main compounds responsible for sprouts’ biological activity. Most of the results suggest that the sprouts may play a role in chemoprevention, as a part of the daily diet, with especially encouraging effects observed for broccoli sprouts. However, further research on cultivation conditions, safety profile, the impact of Se-enrichment or pharmacokinetic studies are necessary to assess the effectiveness of sprouts as chemopreventive agents in humans.
    Keywords apoptosis ; bioactive properties ; biofortification ; breasts ; broccoli ; cell proliferation ; chemoprevention ; colon ; healthy diet ; human health ; humans ; lungs ; neoplasm cells ; pharmacokinetics ; probiotics ; rectum ; selenium ; stomach ; systematic review ; technology ; viability ; Sprouts ; Cytotoxic ; Anti-Cancer ; Anti-tumor ; Chemopreventive ; Anti-inflammatory
    Language English
    Dates of publication 2023-09
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 1049246-x
    ISSN 1879-3053 ; 0924-2244
    ISSN (online) 1879-3053
    ISSN 0924-2244
    DOI 10.1016/j.tifs.2023.104130
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Erucic Acid-Both Sides of the Story: A Concise Review on Its Beneficial and Toxic Properties.

    Galanty, Agnieszka / Grudzińska, Marta / Paździora, Wojciech / Paśko, Paweł

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 4

    Abstract: Erucic acid (EA) is monounsaturated fatty acid (22:1 n-9), synthesized in the seeds of many plants from ... ...

    Abstract Erucic acid (EA) is monounsaturated fatty acid (22:1 n-9), synthesized in the seeds of many plants from the
    MeSH term(s) Humans ; Rats ; Animals ; Erucic Acids ; Fatty Acids, Monounsaturated ; Brassica napus ; Seeds
    Chemical Substances erucic acid (075441GMF2) ; Erucic Acids ; Fatty Acids, Monounsaturated
    Language English
    Publishing date 2023-02-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28041924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Drought stress during the growing season: Changes in reducing sugars, starch content and respiration rate during storage of two potato cultivars differing in drought sensitivity

    Grudzińska, Magdalena / Boguszewska‐Mańkowska, Dominika / Zarzyńska, Krystyna

    Journal of agronomy and crop science. 2022 Oct., v. 208, no. 5

    2022  

    Abstract: The research was carried out on two potato (Solanum tuberosum L.) varieties with different tolerance to drought stress. Both varieties were cultivated in various moisture conditions: No stress, which uses the natural atmospheric conditions prevailing ... ...

    Abstract The research was carried out on two potato (Solanum tuberosum L.) varieties with different tolerance to drought stress. Both varieties were cultivated in various moisture conditions: No stress, which uses the natural atmospheric conditions prevailing during the growing season and supplemented with water using drip irrigation and two combinations of drought conditions: 40 days stress at tuberizations, and intermittent drought (3 stress periods of 7 days). After harvesting, the tubers were stored at two temperatures, that is, 5°C and 8°C, for 39, 67, 143 and 164 days. The main aim of the research was the evaluation of the reaction of two potato varieties differing in drought stress tolerance to the accumulation of sugars and the respiration rate of tubers. It was found that tubers of drought stress‐sensitive variety (Cekin) accumulated more glucose and fructose than tubers of drought‐resistant variety (Tajfun), regardless of the type of drought applied during the growing season. The applied drought, both constant and intermittent, resulted in an increase in the content of reducing sugars compared with the control conditions. After applying both types of drought during the vegetation period, the respiration rate increased during tuber storage. Larger changes were recorded in the case of an intermittent drought. At a higher storage temperature, in the variety resistant to drought stress, a decrease in glucose content was found after long‐term storage, while in the sensitive variety, the content of this component increased, regardless of the moisture conditions during the growing season.
    Keywords Solanum tuberosum ; agronomy ; cell respiration ; cultivars ; drought ; drought tolerance ; fructose ; glucose ; microirrigation ; potatoes ; starch ; storage temperature ; storage time ; vegetation ; water stress
    Language English
    Dates of publication 2022-10
    Size p. 609-620.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 635552-3
    ISSN 0931-2250
    ISSN 0931-2250
    DOI 10.1111/jac.12498
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Progress in Antimelanoma Research of Natural Triterpenoids and Their Derivatives: Mechanisms of Action, Bioavailability Enhancement and Structure Modifications.

    Grudzińska, Marta / Stachnik, Bogna / Galanty, Agnieszka / Sołtys, Agnieszka / Podolak, Irma

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 23

    Abstract: Melanoma is one of the most dangerous forms of skin cancer, characterized by early metastasis and rapid development. In search for effective treatment options, much attention is given to triterpenoids of plant origin, which are considered promising drug ... ...

    Abstract Melanoma is one of the most dangerous forms of skin cancer, characterized by early metastasis and rapid development. In search for effective treatment options, much attention is given to triterpenoids of plant origin, which are considered promising drug candidates due to their well described anticancer properties and relatively low toxicity. This paper comprehensively summarizes the antimelanoma potential of natural triterpenoids, that are also used as scaffolds for the development of more effective derivatives. These include betulin, betulinic acid, ursolic acid, maslinic acid, oleanolic acid, celastrol and lupeol. Some lesser-known triterpenoids that deserve attention in this context are 22
    MeSH term(s) Humans ; Biological Availability ; Melanoma/drug therapy ; Triterpenes/pharmacology ; Triterpenes/chemistry ; Antineoplastic Agents/chemistry
    Chemical Substances Triterpenes ; Antineoplastic Agents
    Language English
    Publishing date 2023-11-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28237763
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  8. Article: Influence of Linseed Oil Varnish Admixture on Glauconite Clay Mortar Properties.

    Brzyski, Przemysław / Grudzińska, Magdalena

    Materials (Basel, Switzerland)

    2020  Volume 13, Issue 23

    Abstract: Raw clay is used nowadays in construction as a component of mortars and plasters and as a binder in composites based on straw or shives. It is a material with good sorption properties and vapor permeability, but it is susceptible to shrinkage, is not ... ...

    Abstract Raw clay is used nowadays in construction as a component of mortars and plasters and as a binder in composites based on straw or shives. It is a material with good sorption properties and vapor permeability, but it is susceptible to shrinkage, is not resistant to water, and also is characterized by low mechanical strength, which makes it impossible to be used, for example, in external plasters. Various additives and admixtures are used to improve selected properties of clay mortars. The article presents the research results and assessment of the effect of glauconite clay mortar modification with an admixture of linseed oil varnish on selected properties. Admixtures in the amounts of 1%, 2%, and 3% in relation to clay weight were used. Flexural and compressive strength, water resistance, shrinkage, drying capacity, density, and porosity of mortar, were tested. The admixture of linseed oil varnish in the amounts used in the investigation had a positive effect on some of the tested properties; regardless of the quantity of the admixture, the modified mortars had better parameters concerning flexural strength, shrinkage reduction, and water resistance than the reference mortar, without admixture.
    Language English
    Publishing date 2020-12-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma13235487
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  9. Article ; Online: Reconditioning and weather conditions affect black spot damage during storage of potato (Solanum tuberosum L.) tubers.

    Grudzińska, Magdalena / Mańkowski, Dariusz

    Journal of the science of food and agriculture

    2019  Volume 99, Issue 11, Page(s) 4913–4921

    Abstract: Background: In potatoes (Solanum tuberosum L.), mechanical damage can cause the formation of black spots in the tuber flesh as the result of oxidation of phenolic compounds. This damage can result in substantial economic losses and degradation of ... ...

    Abstract Background: In potatoes (Solanum tuberosum L.), mechanical damage can cause the formation of black spots in the tuber flesh as the result of oxidation of phenolic compounds. This damage can result in substantial economic losses and degradation of quality. External factors contributing to the formation and the prevention of black spot damage (BSD) are not fully understood. The aim of this study was to determine the effect of weather conditions, using a hydrothermal coefficient, and of two potato tuber reconditioning methods on the formation of BSD. Five potato varieties were divided into high, moderate and low BSD susceptibility groups. The research was carried out over two growing seasons that differed greatly in precipitation and temperature. The black spot index was determined immediately after harvest and after 3 and 7 months of storage. Two reconditioning methods, applied for 7 days at 8 °C and for 7 days at 15 °C, were used for each variety.
    Results: The incidence of BSD in susceptible varieties did not depend significantly on weather conditions, although statistically significant variation was observed. We found a correlation between the hydrothermal coefficient (dry conditions) and BSD in the Etiuda variety. There was no significant effect of storage time and temperature on BSD incidence in susceptible or moderately susceptible varieties. The reconditioning methods significantly reduced the formation of BSD in tubers after storage in all three groups. Regardless of the level of susceptibility of the variety, storage time and storage temperature, the most efficient treatment to limit BSD was reconditioning for 7 days at 15 °C.
    Conclusion: Identification of the significant effects of weather, and strong reduction of BSD in tubers that had been reconditioned, allows examination of the underlying mechanisms. The described reconditioning method can lead to satisfactory reduction of BSD in potato tubers. Data from this research will be of interest to potato breeders, particularly if valuable alleles that affect this phenomeon can be isolated. © 2019 Society of Chemical Industry.
    MeSH term(s) Food Handling/methods ; Food Quality ; Food Storage/methods ; Oxidation-Reduction ; Phenols/chemistry ; Plant Tubers/chemistry ; Plant Tubers/growth & development ; Solanum tuberosum/chemistry ; Solanum tuberosum/genetics ; Species Specificity ; Temperature ; Weather
    Chemical Substances Phenols
    Language English
    Publishing date 2019-05-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 184116-6
    ISSN 1097-0010 ; 0022-5142
    ISSN (online) 1097-0010
    ISSN 0022-5142
    DOI 10.1002/jsfa.9719
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  10. Article: Critical Assessment of the Anti-Inflammatory Potential of Usnic Acid and Its Derivatives-A Review.

    Paździora, Wojciech / Podolak, Irma / Grudzińska, Marta / Paśko, Paweł / Grabowska, Karolina / Galanty, Agnieszka

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 4

    Abstract: Inflammation is a response of the organism to an external factor that disrupts its natural homeostasis, and it helps to eliminate the cause of tissue injury. However, sometimes the body's response is highly inadequate and the inflammation may become ... ...

    Abstract Inflammation is a response of the organism to an external factor that disrupts its natural homeostasis, and it helps to eliminate the cause of tissue injury. However, sometimes the body's response is highly inadequate and the inflammation may become chronic. Thus, the search for novel anti-inflammatory agents is still needed. One of the groups of natural compounds that attract interest in this context is lichen metabolites, with usnic acid (UA) as the most promising candidate. The compound reveals a broad spectrum of pharmacological properties, among which anti-inflammatory properties have been studied both in vitro and in vivo. The aim of this review was to gather and critically evaluate the results of the so-far published data on the anti-inflammatory properties of UA. Despite some limitations and shortcomings of the studies included in this review, it can be concluded that UA has interesting anti-inflammatory potential. Further research should be directed at the (i) elucidation of the molecular mechanism of UA; (ii) verification of its safety; (iii) comparison of the efficacy and toxicity of UA enantiomers; (iv) design of UA derivatives with improved physicochemical properties and pharmacological activity; and (v) use of certain forms or delivery carriers of UA, especially in its topical application.
    Language English
    Publishing date 2023-04-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13041046
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