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  1. Article: [Analysis of clinical characteristics of children with adenoid hypertrophy and pharyngolaryngeal reflux].

    Lin, F / Zhao, J / Lu, Y X / Zou, J Z / Xiao, P / Liang, J Q / Pang, C / Gu, Q L

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2024  Volume 59, Issue 2, Page(s) 140–146

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Child ; Humans ; Adenoids ; Pepsin A/metabolism ; Laryngopharyngeal Reflux/diagnosis ; Laryngeal Edema ; Edema ; Hypertrophy ; Erythema
    Chemical Substances Pepsin A (EC 3.4.23.1)
    Language Chinese
    Publishing date 2024-02-18
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.cn115330-20231221-00318
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [The effects of nucleotide-binding oligomerization domain-like receptor 3 inflammasome on obstructive sleep apnea and its complications].

    Wang, R K / Liang, J Q / Lu, Y X / Zhan, X J / Gu, Q L

    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

    2023  Volume 57, Issue 9, Page(s) 1510–1516

    Abstract: Obstructive sleep apnea (OSA) is a sleep disorder with a high incidence and severe impact on the human body, which can induce systemic chronic inflammatory responses. Chronic inflammation is an important cause of exacerbation of OSA and its associated ... ...

    Abstract Obstructive sleep apnea (OSA) is a sleep disorder with a high incidence and severe impact on the human body, which can induce systemic chronic inflammatory responses. Chronic inflammation is an important cause of exacerbation of OSA and its associated complications. Nucleotide-binding oligomerization domain-like receptor 3 (NLRP3) is an inflammasome that is widely found in epithelial cells and immune cells and plays an important role in inflammatory diseases as an important component of innate immunity. Research evidence suggests that the activation of NLRP3 inflammasomes can exacerbate the damage to neurons, endothelial cells, lung and kidney caused by OSA, and these effects can be eliminated by genetic or pharmacological deletion of NLRP3. Targeting inhibition of NLRP3 inflammasome may serve as a co-therapeutic strategy for OSA-induced related complications. This article reviews NLRP3 inflammasome and its mechanism in OSA-related concurrent diseases, which can provide scientific basis for prevention and intervention of OSA and its related complications.
    MeSH term(s) Humans ; Inflammasomes ; Endothelial Cells ; NLR Family, Pyrin Domain-Containing 3 Protein ; Inflammation ; Sleep Apnea, Obstructive ; Nucleotides
    Chemical Substances Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein ; Nucleotides
    Language Chinese
    Publishing date 2023-09-24
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 604575-3
    ISSN 0253-9624
    ISSN 0253-9624
    DOI 10.3760/cma.j.cn112150-20221120-01131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Research progress of liver sinusoidal endothelial cells in the regulation of liver microenvironment to affect liver fibrosis].

    Deng, X X / Li, H / Zhang, Z F / Gu, Q L

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2020  Volume 28, Issue 4, Page(s) 357–360

    Abstract: Liver sinusoidal endothelial cells (LSECs) are not only important intermediary cells for substance exchange between blood and hepatocytes, but also important hepatic non-parenchymal cells to cause liver fibrosis and cirrhosis because of chronic liver ... ...

    Abstract Liver sinusoidal endothelial cells (LSECs) are not only important intermediary cells for substance exchange between blood and hepatocytes, but also important hepatic non-parenchymal cells to cause liver fibrosis and cirrhosis because of chronic liver injury factors. It mainly regulates the liver microcirculation and participates in the development of hepatic fibrosis by interacting with hepatic stellate cells (HSCs), hepatocytes, Kupffer cells and mediating hepatic stiffness and hepatic angiogenesis. Hence, clarifying these mechanisms will help to explore new targets and strategies for the treatment of liver fibrosis.
    MeSH term(s) Endothelial Cells/cytology ; Hepatic Stellate Cells ; Hepatocytes ; Humans ; Kupffer Cells ; Liver/cytology ; Liver/pathology ; Liver Cirrhosis/pathology
    Language Chinese
    Publishing date 2020-05-04
    Publishing country China
    Document type Journal Article ; Review
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20190715-00247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Prevalence of allergic rhinitis in Chinese children from 2001 to 2021: Meta analysis].

    Wang, R K / Liang, J Q / Han, W / Wang, W P / Lu, Y X / Gu, Q L

    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

    2022  Volume 56, Issue 6, Page(s) 784–793

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; China/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Retrospective Studies ; Rhinitis ; Rhinitis, Allergic/epidemiology
    Language Chinese
    Publishing date 2022-07-04
    Publishing country China
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 604575-3
    ISSN 0253-9624
    ISSN 0253-9624
    DOI 10.3760/cma.j.cn112150-20220315-00242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Effect of treating obstructive sleep apnea-hypopnea syndrome on chronic cough in children].

    Pang, C / Liang, J Q / Gu, Q L

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2017  Volume 52, Issue 8, Page(s) 586–591

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Child ; Chronic Disease ; Cough/etiology ; Cough/surgery ; Humans ; Polysomnography ; Quality of Life ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/surgery ; Syndrome ; Time Factors
    Language Chinese
    Publishing date 2017-08-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.issn.1673-0860.2017.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Recurrent acute promyaelocytic leukemia with paraplegic onset was treated with surgery and chemotherapy: a case report and literature review].

    Zhou, Z G / Liu, Z L / Gu, Q L / Liu, H X / Du, X / Zhuo, J C

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2020  Volume 41, Issue 7, Page(s) 599–600

    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols ; Humans ; Leukemia, Myeloid, Acute/complications ; Leukemia, Myeloid, Acute/therapy ; Paraplegia/etiology ; Recurrence
    Language Chinese
    Publishing date 2020-08-18
    Publishing country China
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2020.07.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Study on the correlation between meteorological factors and acute otitis media in outpatients of children in Beijing].

    Lu, Y X / Liang, J Q / Gu, Q L / Yu, X M / Yan, X

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2017  Volume 52, Issue 10, Page(s) 724–728

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Age Factors ; Atmospheric Pressure ; Beijing/epidemiology ; Child ; Child, Preschool ; Environmental Monitoring ; Female ; Humans ; Humidity ; Infant ; Male ; Meteorological Concepts ; Otitis Media/epidemiology ; Outpatients/statistics & numerical data ; Particulate Matter/analysis ; Seasons ; Wind
    Chemical Substances Particulate Matter
    Language Chinese
    Publishing date 2017-10-19
    Publishing country China
    Document type Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.issn.1673-0860.2017.10.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Predicting the maturity of haemodialysis arteriovenous fistulas with colour Doppler ultrasound: a single-centre study from China.

    Zhu, Y-L / Ding, H / Fan, P-L / Gu, Q-L / Teng, J / Wang, W-P

    Clinical radiology

    2016  Volume 71, Issue 6, Page(s) 576–582

    Abstract: Aim: To explore the optimal vascular diameter and blood flow measured by ultrasound to predict fistula maturity in Chinese patients.: Materials and methods: One hundred and thirty-two patients were enrolled in the study. The blood flow and the ... ...

    Abstract Aim: To explore the optimal vascular diameter and blood flow measured by ultrasound to predict fistula maturity in Chinese patients.
    Materials and methods: One hundred and thirty-two patients were enrolled in the study. The blood flow and the diameters of the brachial artery, radial artery, and cephalic vein were analysed according to clinical outcomes. The performances of blood flow, cephalic vein diameter, and the two factors combined in predicting fistula maturity were evaluated and the optimal cut-off values for Chinese patients were determined.
    Results: During a 6 month follow-up, 113 fistulas were classified as mature and 19 fistulas were classified as failure. In both groups, the diameters of the brachial and radial arteries increased gradually within 2 weeks post-surgery (p<0.05), and cephalic vein diameter and blood flow increased within 4 weeks post-surgery (p<0.05). The blood flow of the failure group was significantly lower than that of the mature group from the first day after creation. The area under the receiver operating characteristic (ROC) curve was 0.95 (529 ml/min, the optimal cut-off value) for blood flow, 0.83 (5.2 mm) for cephalic vein diameter, and 0.96 for the two factors combined in predicting fistula maturity.
    Conclusions: For Chinese patients, blood flow >529 ml/min could be used to predict fistula maturity and cephalic vein diameter >5.2 mm could be a supplement when necessary.
    MeSH term(s) Anastomosis, Surgical/methods ; Blood Flow Velocity ; China ; Graft Survival ; Humans ; Male ; Middle Aged ; Radial Artery/diagnostic imaging ; Radial Artery/physiopathology ; Radial Artery/surgery ; Renal Dialysis/methods ; Reproducibility of Results ; Sensitivity and Specificity ; Ultrasonography, Doppler, Color/methods ; Veins/diagnostic imaging ; Veins/physiopathology ; Veins/surgery
    Language English
    Publishing date 2016-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 391227-9
    ISSN 1365-229X ; 0009-9260
    ISSN (online) 1365-229X
    ISSN 0009-9260
    DOI 10.1016/j.crad.2016.02.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Upregulated Hoxc6 expression is associated with poor survival in gastric cancer patients.

    Zhang, Q / Jin, X S / Yang, Z Y / Wei, M / Liu, B Y / Gu, Q L

    Neoplasma

    2013  Volume 60, Issue 4, Page(s) 439–445

    Abstract: Human Hox genes (Homeobox) have crucial roles in development and differentiation, regulating numerous processes including apoptosis, receptor signalling, differentiation, motility and angiogenesis. Aberrant expression of Hoxc6 gene has been reported in ... ...

    Abstract Human Hox genes (Homeobox) have crucial roles in development and differentiation, regulating numerous processes including apoptosis, receptor signalling, differentiation, motility and angiogenesis. Aberrant expression of Hoxc6 gene has been reported in several tumor tissues and cancer cell lines. The prognostic significance of Hoxc6 in gastric cancer remains largely unknown.This study was aimed to investigate the clinical significance of Hoxc6 in gastric cancer.Total RNA of paired tissue samples (n=25) and a tissue microarray containing 161 paired tissues from patients with gastric cancers at different stages were collected. Quantitative real-time PCR and immunochemistry assay were carried out to investigate the expression of Hoxc6. Hoxc6 mRNA was increased in gastric cancer tissues ( 16 of 25) compared with the adjacent normal mucosa (P<0.05). Immunohistochemical detection showed that expression of Hoxc6 was associated with the depth of tumor invasion (P<0.05). Patients with higher expression levels of Hoxc6 had a shorter overall survival rate (P<0.05).Hoxc6 might contribute to the progression of gastric carcinogenesis and may be a significant predictor of poor survival in patients with gastric cancer after curative operations.
    MeSH term(s) Adult ; Aged ; Female ; Homeodomain Proteins/analysis ; Homeodomain Proteins/genetics ; Homeodomain Proteins/physiology ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Neoplasm Invasiveness ; Prognosis ; RNA, Messenger/analysis ; Stomach Neoplasms/chemistry ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology ; Up-Regulation
    Chemical Substances HOXC6 protein, human ; Homeodomain Proteins ; RNA, Messenger
    Language English
    Publishing date 2013
    Publishing country Slovakia
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 415445-9
    ISSN 0028-2685
    ISSN 0028-2685
    DOI 10.4149/neo_2013_057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: An integrated logistics operational model for remanufacturing/manufacturing systems based on the consumer market

    Gu, Q. L / Ji, J. H

    International journal of logistics systems and management Vol. 4, No. 1 , p. 21-39

    2008  Volume 4, Issue 1, Page(s) 21–39

    Author's details Q. L. Gu; J. H. Ji
    Keywords Betriebliche Kreislaufwirtschaft ; Kostenmanagement ; Lagerhaltungsmodell ; Theorie
    Language English
    Size graph. Darst.
    Publisher Inderscience
    Publishing place Olney
    Document type Article
    ZDB-ID 2178795-5
    Database ECONomics Information System

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