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  1. Article ; Online: ASO Author Reflections: Low-grade Appendiceal Mucinous Neoplasia (LAMN): Which Criteria for a "Watch and Wait" Strategy?

    Guaglio, Marcello

    Annals of surgical oncology

    2018  Volume 25, Issue Suppl 3, Page(s) 774–775

    MeSH term(s) Adenocarcinoma, Mucinous ; Appendiceal Neoplasms ; Humans ; Prospective Studies
    Language English
    Publishing date 2018-11-27
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-018-7047-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: In response to: Transanal surgery during COVID-19 pandemic in Lombardy.

    Sorrentino, L / Guaglio, M / Cosimelli, M

    Journal of surgical oncology

    2020  Volume 122, Issue 5, Page(s) 996

    MeSH term(s) COVID-19 ; Humans ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-15
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.26122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: ASO Author Reflections: Preoperative Staging for Nongynecological Peritoneal Malignancies Mimicking Ovarian Cancer-Making the Omelet without Breaking the Eggs.

    Guaglio, Marcello / Baratti, Dario

    Annals of surgical oncology

    2021  Volume 28, Issue 5, Page(s) 2909–2910

    MeSH term(s) Carcinoma, Ovarian Epithelial ; Female ; Humans ; Ovarian Neoplasms/diagnosis ; Peritoneal Neoplasms/diagnosis
    Language English
    Publishing date 2021-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-021-09681-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: ASO Author Reflections: Perioperative Systemic Chemotherapy in Diffuse Malignant Peritoneal Mesothelioma treated with CRS-HIPEC.

    Chatterjee, Ambarish / Kusamura, Shigeki / Baratti, Dario / Guaglio, Marcello / Battaglia, Luigi / Deraco, Marcello

    Annals of surgical oncology

    2024  Volume 31, Issue 4, Page(s) 2511–2512

    MeSH term(s) Humans ; Hyperthermic Intraperitoneal Chemotherapy ; Mesothelioma, Malignant/therapy ; Mesothelioma/drug therapy ; Mesothelioma/pathology ; Peritoneal Neoplasms/pathology ; Cytoreduction Surgical Procedures ; Hyperthermia, Induced ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Combined Modality Therapy ; Retrospective Studies
    Language English
    Publishing date 2024-01-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13768-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Indocyanine green-guided lymphadenectomy of the inferior mesenteric artery in laparoscopic total mesorectal excision for low rectal cancer after neoadjuvant chemoradiotherapy - A Video Vignette.

    Colletti, Gaia / Battaglia, Luigi / Sorrentino, Luca / Guaglio, Marcello / Cosimelli, Maurizio

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2022  Volume 24, Issue 4, Page(s) 547

    MeSH term(s) Chemoradiotherapy ; Humans ; Indocyanine Green ; Laparoscopy ; Lymph Node Excision ; Mesenteric Artery, Inferior/surgery ; Neoadjuvant Therapy ; Rectal Neoplasms/surgery ; Treatment Outcome
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2022-01-06
    Publishing country England
    Document type Letter ; Video-Audio Media
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Risk factors for gastrointestinal perforation and anastomotic leak in patients submitted to cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).

    Nogueiro, Jorge / Fathi, Nik Qisti / Guaglio, Marcello / Baratti, Dario / Kusamura, Shigeki / Deraco, Marcello

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2023  Volume 49, Issue 10, Page(s) 107020

    Abstract: Background: Gastrointestinal leak is one of the most feared complications after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) and harbors significant postoperative morbidity and mortality. We aim to identify risk- ... ...

    Abstract Background: Gastrointestinal leak is one of the most feared complications after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) and harbors significant postoperative morbidity and mortality. We aim to identify risk-factors for anastomotic leak (AL) and gastrointestinal perforation (GP) to optimize postoperative outcomes of this population.
    Methods: We performed a retrospective analysis of 1043 consecutive patients submitted to CRS in a single institution. Potential risk factors for AL and GP, both related to patient overall condition, disease status and surgical technique were reviewed.
    Results: Anastomotic leaks were identified in 5.2% of patients, and GPs in 7.0%. The independent risk-factors for AL were age at surgery (OR1.40; CI95% 1.10-1.79); peritoneal cancer index (PCI) (OR1.04, CI95% 1.01-1.07); Cisplatin dose >240 mg during HIPEC (OR3.53; CI95% 1.47-8.56) and the presence of colorectal (CR) or colo-colic (CC) anastomosis (OR5.09; CI95% 2.71-9.53, and 4.58; CI95% 1.22-17.24 respectively). Male gender and intraoperative red blood cell transfusions were the only independent risk factors for GP identified (OR1.70; CI95% 1.04-2.78 and 1.06; CI95% 1.01-1.12, respectively). Regarding 30-day and 90-day postoperative mortality, independent risk-factors were mainly related to patient's overall condition.
    Conclusion: Gastrointestinal leaks are a frequent source of postoperative morbidity, mainly at the expense of GP. A careful and systematic intraoperative revision of all potential gastrointestinal injuries is equally critical to perfecting anastomotic fashioning techniques to decrease gastrointestinal complication rates. We identified multiple risk-factors for AL and GP related to disease status and patient condition. Our study suggests that patient-related conditions are of paramount relevance, highlighting the importance of patient selection and preoperative patient optimization.
    MeSH term(s) Humans ; Male ; Anastomotic Leak/epidemiology ; Anastomotic Leak/etiology ; Hyperthermic Intraperitoneal Chemotherapy ; Combined Modality Therapy ; Peritoneal Neoplasms/therapy ; Prognosis ; Cytoreduction Surgical Procedures/adverse effects ; Retrospective Studies ; Chemotherapy, Cancer, Regional Perfusion/adverse effects ; Hyperthermia, Induced/adverse effects ; Risk Factors ; Survival Rate
    Language English
    Publishing date 2023-08-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2023.107020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Impact of Perioperative Systemic Chemotherapy on Survival for Patients Who have Diffuse Malignant Peritoneal Mesothelioma Treated with CRS-HIPEC.

    Chatterjee, Ambarish / Kusamura, Shigeki / Baratti, Dario / Guaglio, Marcello / Battaglia, Luigi / Deraco, Marcello

    Annals of surgical oncology

    2023  Volume 31, Issue 1, Page(s) 556–566

    Abstract: Background: The available data on the role of perioperative systemic chemotherapy (SC) for diffuse malignant peritoneal mesothelioma (DMPM) patients undergoing (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is heterogeneous and ... ...

    Abstract Background: The available data on the role of perioperative systemic chemotherapy (SC) for diffuse malignant peritoneal mesothelioma (DMPM) patients undergoing (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is heterogeneous and unstandardized. This study aimed to evaluate the impact of SC on the survival outcomes of DMPM patients undergoing CRS-HIPEC and to identify prognostic factors that affect the decision to administer SC.
    Methods: Patients who underwent CRS-HIPEC in the National Cancer Institute Milan (1995-2020) were retrospectively analyzed using propensity score-matching of known covariates. The patients were grouped into three groups: group A (neoadjuvant chemotherapy [NACT] and no-SC), group B (no-SC and adjuvant chemotherapy [ACT]), and group C (NACT and ACT). Overall survival (OS) and progression-free survival (PFS) were calculated using the Kaplan-Meir method, and prognostic factors were calculated using the Cox-regression method.
    Results: After a median follow-up period of 45 months (95% confidence interval [CI], 6.348-83.652 months) for group A, 115 months (95% CI, 44.379-185.621 months) for group B, and 88 months (95% CI, 3.296-172.704 months) for group C, the study analyzed 154 DMPM patients consisting of matched group A (NACT: 60 + no-SC: 52 = 112), group B (ACT: 38 + no-SC: 38 = 76), and group C (NACT: 31 + ACT: 31 = 62). The patients undergoing ACT had better 5-year OS and PFS than the patients undergoing NACT. In the multivariate analysis, ACT was significantly associated with improved OS by 48% (hazard ratio [HR], 0.52; 95% CI, 0.280-0.965, p = 0.038). For PFS, the association of ACT did not reach statistical significance (HR, 0.531; 95% CI, 0.266-1.058; p = 0.072).
    Conclusion: The optimum treatment sequence for DMPM is CRS-HIPEC followed by adjuvant chemotherapy for high-risk patients. Upfront surgery appears preferable to NACT for patients amenable to complete CRS.
    MeSH term(s) Humans ; Mesothelioma/pathology ; Hyperthermic Intraperitoneal Chemotherapy ; Retrospective Studies ; Lung Neoplasms/pathology ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Hyperthermia, Induced/methods ; Mesothelioma, Malignant/drug therapy ; Peritoneal Neoplasms/surgery ; Cytoreduction Surgical Procedures/methods ; Survival Rate ; Combined Modality Therapy
    Language English
    Publishing date 2023-11-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13640-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: In response to

    Sorrentino, L. / Guaglio, M. / Cosimelli, M.

    Journal of Surgical Oncology ; ISSN 0022-4790 1096-9098

    Transanal surgery during COVID‐19 pandemic in Lombardy

    2020  

    Keywords Surgery ; Oncology ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1002/jso.26122
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Elective colorectal cancer surgery at the oncologic hub of Lombardy inside a pandemic COVID-19 area.

    Sorrentino, Luca / Guaglio, Marcello / Cosimelli, Maurizio

    Journal of surgical oncology

    2020  Volume 122, Issue 2, Page(s) 117–119

    MeSH term(s) Aged ; Betacoronavirus/isolation & purification ; COVID-19 ; Colorectal Neoplasms/surgery ; Colorectal Neoplasms/virology ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Digestive System Surgical Procedures/methods ; Digestive System Surgical Procedures/standards ; Disease Transmission, Infectious/prevention & control ; Female ; Humans ; Infection Control/methods ; Infection Control/standards ; Italy/epidemiology ; Male ; Middle Aged ; Minimally Invasive Surgical Procedures/methods ; Minimally Invasive Surgical Procedures/standards ; Pandemics/prevention & control ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.26052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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