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  1. Article ; Online: To donate, or not to donate, that is the question: Latino insights into brain donation.

    Morlett Paredes, Alejandra / Guareña, Lesley A / Stickel, Ariana M / Schairer, Cynthia E / González, Hector M

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    2022  Volume 19, Issue 4, Page(s) 1274–1280

    Abstract: Introduction: Latinos are underrepresented in brain autopsy research on Alzheimer's disease and related dementias (ADRD). The study's purpose is to identify Latinos' attitudes about brain donation (BD) to inform methods by which researchers can increase ...

    Abstract Introduction: Latinos are underrepresented in brain autopsy research on Alzheimer's disease and related dementias (ADRD). The study's purpose is to identify Latinos' attitudes about brain donation (BD) to inform methods by which researchers can increase autopsy consent.
    Methods: Forty Latinos (mean age: 59.4 years) completed a semi-structured interview and were presented with educational information about BD. Participants completed a questionnaire assessing their understanding of BD and willingness to donate their brain for research.
    Results: Among participants, there was near unanimous support for BD to study ADRD after hearing educational information. However, prior to the information presented, participants reported a lack of knowledge about BD and demonstrated a possibility that misunderstandings about BD may affect participation.
    Discussion: While nearly all study participants agree that donating is beneficial for research and for future generations, the lack of BD information must be addressed to help support positive attitudes and willingness for participation.
    MeSH term(s) Humans ; Middle Aged ; Brain ; Health Knowledge, Attitudes, Practice ; Hispanic or Latino ; Surveys and Questionnaires ; Tissue and Organ Procurement
    Language English
    Publishing date 2022-08-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2211627-8
    ISSN 1552-5279 ; 1552-5260
    ISSN (online) 1552-5279
    ISSN 1552-5260
    DOI 10.1002/alz.12755
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  2. Article: NIH Toolbox Emotion Battery Findings Among People with HIV: Normative Comparisons and Clinical Associations.

    Brody, Lilla A / Kamalyan, Lily / Karcher, Kayle / Guarena, Lesley A / Bender, Alexis A / McKenna, Benjamin S / Umlauf, Anya / Franklin, Donald / Marquine, Maria J / Heaton, Robert K

    Patient related outcome measures

    2023  Volume 14, Page(s) 15–30

    Abstract: Purpose: Depression and other aspects of emotional health in people with HIV (PWH) can affect functional independence, disease progression, and overall life quality. This study used the NIH Toolbox Emotion Battery (NIHTB-EB), which assesses many ... ...

    Abstract Purpose: Depression and other aspects of emotional health in people with HIV (PWH) can affect functional independence, disease progression, and overall life quality. This study used the NIH Toolbox Emotion Battery (NIHTB-EB), which assesses many features of emotional health, to more comprehensively investigate differences among adults living with and without HIV, and to identify factors associated with emotional health for PWH.
    Patients and methods: Participants (n=1451; age: M=50.19, SD=16.84; 47.90% women) included 433 PWH living in southern California seen from 2003 to 2021 (64.72% AIDS, 92.25% on antiretroviral therapy) and 1018 healthy participants from NIHTB-EB national normative cohort. Participants completed the NIHTB-EB and PWH underwent comprehensive HIV disease and psychiatric evaluations. We investigated differences in emotional health by HIV status via independent samples
    Results: PWH had significantly worse emotional health than people without HIV across Social Satisfaction (Cohen's d=0.71,
    Conclusion: The NIHTB-EB identified that difficulties with multiple aspects of emotional health are common among PWH, and appear to be relatively independent of cognitive impairment as well as HIV disease and treatment history, but are strongly associated with everyday functioning. Given the cross-sectional nature of this study, longitudinal studies should be employed to evaluate causality pertaining to predictors of emotional health in PWH. These findings may inform interventions to promote emotional wellbeing in PWH.
    Language English
    Publishing date 2023-02-15
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2586660-6
    ISSN 1179-271X
    ISSN 1179-271X
    DOI 10.2147/PROM.S391113
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  3. Article ; Online: Emotional health and its association with neurocognition in Hispanic and non-Hispanic White people with HIV.

    Guareña, Lesley A / Kamalyan, Lily / Watson, Caitlin Wei-Ming / Karcher, Kayle / Umlauf, Anya / Morgan, Erin / Moore, David / Ellis, Ronald / Grant, Igor / Cherner, Mariana / Moore, Raeanne C / Zlatar, Zvinka Z / Heaton, Robert K / Marquine, María J

    Journal of the International Neuropsychological Society : JINS

    2023  Volume 30, Issue 1, Page(s) 56–66

    Abstract: Objective: Emotional functioning is linked to HIV-associated neurocognitive impairment, yet research on this association among diverse people with HIV (PWH) is scant. We examined emotional health and its association with neurocognition in Hispanic and ... ...

    Abstract Objective: Emotional functioning is linked to HIV-associated neurocognitive impairment, yet research on this association among diverse people with HIV (PWH) is scant. We examined emotional health and its association with neurocognition in Hispanic and White PWH.
    Methods: Participants included 107 Hispanic (41% primarily Spanish-speakers; 80% Mexican heritage/origin) and 216 White PWH (Overall age:
    Results: 27%-39% of the sample had problematic socioemotional summary scores. Hispanic PWH showed less loneliness, better social satisfaction, higher meaning and purpose, and better psychological well-being than Whites (
    Conclusion: Adverse emotional health is common among PWH, with subgroups of Hispanics showing relative strengths in some domains. Aspects of emotional health differentially relate to neurocogntition among PWH and cross-culturally. Understanding these varying associations is an important step towards the development of culturally relevant interventions that promote neurocognitive health among Hispanic PWH.
    MeSH term(s) Female ; Humans ; Male ; Cognition ; Emotions ; Fear ; HIV Infections/complications ; HIV Infections/psychology ; White People/ethnology ; Hispanic or Latino/ethnology ; Hispanic or Latino/psychology ; Adult ; Middle Aged ; Aged
    Language English
    Publishing date 2023-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1230632-0
    ISSN 1469-7661 ; 1355-6177
    ISSN (online) 1469-7661
    ISSN 1355-6177
    DOI 10.1017/S1355617723000188
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  4. Article ; Online: Disparities in Metabolic Syndrome and Neurocognitive Function Among Older Hispanics/Latinos with Human Immunodeficiency Virus.

    Marquine, María J / Kamalyan, Lily / Zlatar, Zvinka Z / Yassai-Gonzalez, David / Perez-Tejada, Alán / Umlauf, Anya / Al-Rousan, Tala / González, Verónica / Breton, Jordana / Guareña, Lesley A / Brody, Lilla / Cherner, Mariana / Ellis, Ronald J / Zúñiga, Maria Luisa / Mungas, Dan M / Moore, Raeanne C / Moore, David J / Wojna, Valerie / Hall, Rasheeda K /
    Franklin, Donald R / Heaton, Robert K

    AIDS patient care and STDs

    2024  

    Abstract: Neurocognitive impairment and metabolic syndrome (MetS) are prevalent in persons with HIV (PWH). We examined disparities in HIV-associated neurocognitive function between Hispanic and non-Hispanic White older PWH, and the role of MetS in explaining these ...

    Abstract Neurocognitive impairment and metabolic syndrome (MetS) are prevalent in persons with HIV (PWH). We examined disparities in HIV-associated neurocognitive function between Hispanic and non-Hispanic White older PWH, and the role of MetS in explaining these disparities. Participants included 116 community-dwelling PWH aged 50-75 years enrolled in a cohort study in southern California [58 Hispanic (53% Spanish speaking) and 58 age-comparable non-Hispanic White; overall group: age:
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1326868-5
    ISSN 1557-7449 ; 0893-5068 ; 1087-2914
    ISSN (online) 1557-7449
    ISSN 0893-5068 ; 1087-2914
    DOI 10.1089/apc.2024.0043
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  5. Article ; Online: Influence of Educational Background, Childhood Socioeconomic Environment, and Language Use on Cognition among Spanish-Speaking Latinos Living Near the US-Mexico Border.

    Kamalyan, Lily / Guareña, Lesley A / Díaz-Santos, Mirella / Suarez, Paola / Cherner, Mariana / García Alcorn, Marlen Y / Umlauf, Anya / Franklin, Donald R / Rivera Mindt, Monica / Artiola I Fortuny, Lidia / Heaton, Robert K / Marquine, María J

    Journal of the International Neuropsychological Society : JINS

    2021  Volume 28, Issue 8, Page(s) 876–890

    Abstract: Objectives: We investigated the impact of culturally relevant social, educational, and language factors on cognitive test performance among Spanish speakers living near the US-Mexico border.: Methods: Participants included 254 healthy native Spanish ... ...

    Abstract Objectives: We investigated the impact of culturally relevant social, educational, and language factors on cognitive test performance among Spanish speakers living near the US-Mexico border.
    Methods: Participants included 254 healthy native Spanish speakers from the Neuropsychological Norms for the US-Mexico Border Region in Spanish (NP-NUMBRS) project (Age:
    Results: Several culturally relevant variables were significantly associated with unadjusted Global Scaled Scores in univariable analyses. When using demographically adjusted
    Conclusions: Demographically adjusted normative data provide a useful tool for the identification of brain dysfunction, as these account for much of the variance of sociocultural factors on cognitive test performance. Yet, certain culturally relevant variables still contributed to cognitive test performance above and beyond basic demographics, warranting further investigation.
    MeSH term(s) Child ; Cognition ; Educational Status ; Female ; Hispanic or Latino ; Humans ; Language ; Male ; Mexico ; Neuropsychological Tests
    Language English
    Publishing date 2021-09-06
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1230632-0
    ISSN 1469-7661 ; 1355-6177
    ISSN (online) 1469-7661
    ISSN 1355-6177
    DOI 10.1017/S1355617721001028
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    In stock of ZB MED Cologne/Königswinter

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