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  1. AU="Guedes-Guedes, Isabel"
  2. AU="Xiaoli Chang"
  3. AU="Jang, Joonseong"
  4. AU="Sergio Lafuente-Arroyo"
  5. AU="Löppönen, Heikki"
  6. AU="Santos, Maria Leonor"
  7. AU=Saluja Bharat
  8. AU="Nezhadi, Akram"
  9. AU=Dhar Debojyoti
  10. AU="Chandrappa S"
  11. AU="Cole, Kevin"
  12. AU=De Ceukelaire Wim
  13. AU=Tomatis L
  14. AU=Chandra Sharad
  15. AU="Mishra, Malvika"
  16. AU="Bruggemann, Kira"
  17. AU="Miura, Tanya A."
  18. AU="Kobeasy, Mohamed I."
  19. AU="Sonthonnax, Florian" AU="Sonthonnax, Florian"
  20. AU="Wang, Rongzu"

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  1. Artikel: Glaucoma Incidence and Progression in Diabetics: The Canary Islands Study Using the Laguna ONhE Application.

    Gonzalez-Hernandez, Marta / Gonzalez-Hernandez, Daniel / Betancor-Caro, Nisamar / Guedes-Guedes, Isabel / Guldager, Morten Kirk / Gonzalez de la Rosa, Manuel

    Journal of clinical medicine

    2022  Band 11, Heft 24

    Abstract: Background: Laguna ONhE provides a globin distribution function (GDF), in which a glaucoma discriminator based on deep learning plays an important role, and there is also an optimized globin individual pointer (GIP) for progression analysis. Methods: ... ...

    Abstract Background: Laguna ONhE provides a globin distribution function (GDF), in which a glaucoma discriminator based on deep learning plays an important role, and there is also an optimized globin individual pointer (GIP) for progression analysis. Methods: Signs of optic nerve glaucoma were identified in 1,124,885 fundus images from 203,115 diabetics obtained over 15 years and 117,813 control images. Results: A total of 743,696 images from 313,040 eyes of 173,661 diabetics were analysed. Some exclusions occurred due to excessive illumination, poor quality, or the absence of optic discs. Suspicion of glaucoma was reported in 6.70%, for an intended specificity of 99% (GDF < −15). More signs of glaucoma occur in diabetics as their years of disease increase, and after age 60, compared to controls. The GIP detected progression (p < 0.01) in 2.59% of cases with 4 controls and in 42.6% with 14 controls was higher in cases with lower GDF values. The GDF was corrected for the disc area and proved to be independent of it (r = 0.001925; p = 0.2814). Conclusions: The GDF index suggests a higher and increasing glaucoma probability in diabetics over time. Doubling the number of check-ups from four to eight increases the ability to detect GIP index progression by a factor of 5.
    Sprache Englisch
    Erscheinungsdatum 2022-12-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11247294
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Identification of Glaucoma in Diabetics Using the Laguna-ONhE Colourimetric Method and OCT Spectralis.

    Gonzalez-Hernandez, Marta / Betancor-Caro, Nisamar / Mesa-Lugo, Fatima / Rodriguez-Talavera, Ivan / Pareja-Rios, Alicia / Guedes-Guedes, Isabel / Estevez-Jorge, Beatriz / Trujillo-Blanco, Maricela / Cordova-Villegas, Roberto / Espinoza-Gonzalez, Juan / Siguero-Martin, Leticia / Goya-Gonzalez, Carolina / Rodriguez-Dominguez, Maria / Gonzalez-Hernandez, Daniel / Gonzalez de la Rosa, Manuel

    Journal of clinical medicine

    2023  Band 12, Heft 18

    Abstract: Background: Previous retrospective results are evaluated prospectively and blinded.: Methods: A total of 221 eyes previously classified as normal (G1), 279 as moderate risk of glaucoma (G2) and 217 as high risk (G3) according to the Globin ... ...

    Abstract Background: Previous retrospective results are evaluated prospectively and blinded.
    Methods: A total of 221 eyes previously classified as normal (G1), 279 as moderate risk of glaucoma (G2) and 217 as high risk (G3) according to the Globin Discriminant Function (GDF) Laguna-ONhE index were examined with OCT Spectralis- Results: In G1, the Bruch's Membrane Opening Minimum Rim Width (BMO-MRW) was 332 ± 55 microns; in G2, it was 252 ± 47 (
    Conclusions: In some cases, these defects appear to be mainly glaucomatous, and in others, they are associated with diabetic microangiopathy. In normal tension glaucoma, RNFL defects may be less severe than those inside the nerve.
    Sprache Englisch
    Erscheinungsdatum 2023-09-10
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12185876
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

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