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Article: The impact of COVID-19 on memory: Recognition for masked and unmasked faces.

Guerra, Natália / Pinto, Raquel / Mendes, Pedro S / Rodrigues, Pedro F S / Albuquerque, Pedro B

2022 Volume 13, Page(s) 960941

Abstract: Considering the current state of the worldwide pandemic, it is still common to encounter people wearing face protection masks. Although a safety measure against COVID-19, face masks might be compromising our capacity for face recognition. We conducted an ...

Abstract	Considering the current state of the worldwide pandemic, it is still common to encounter people wearing face protection masks. Although a safety measure against COVID-19, face masks might be compromising our capacity for face recognition. We conducted an online study where 140 participants observed masked and unmasked faces in a within-subjects design and then performed a recognition memory task. The best performance was found when there were no masks either at study and test phase, i.e., at the congruent unmasked condition. The worst performance was found for faces encoded with a mask but tested without it (i.e., masked-unmasked incongruent condition), which can be explained by the disruption in holistic face processing and the violation of the encoding specificity principle. Interestingly, considering the unmasked-masked incongruent condition, performance was probably affected by the violation of the encoding specificity principle but protected by holistic processing that occurred during encoding.
Language	English
Publishing date	2022-10-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.960941
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Article: Explicit Instructions Do Not Enhance Auditory Statistical Learning in Children With Developmental Language Disorder: Evidence From Event-Related Potentials.

Soares, Ana Paula / Gutiérrez-Domínguez, Francisco-Javier / Oliveira, Helena M / Lages, Alexandrina / Guerra, Natália / Pereira, Ana Rita / Tomé, David / Lousada, Marisa

Frontiers in psychology

2022 Volume 13, Page(s) 905762

Abstract: A current issue in psycholinguistic research is whether the language difficulties exhibited by children with developmental language disorder [DLD, previously labeled specific language impairment (SLI)] are due to deficits in their abilities to pick up ... ...

Abstract	A current issue in psycholinguistic research is whether the language difficulties exhibited by children with developmental language disorder [DLD, previously labeled specific language impairment (SLI)] are due to deficits in their abilities to pick up patterns in the sensory environment, an ability known as statistical learning (SL), and the extent to which explicit learning mechanisms can be used to compensate for those deficits. Studies designed to test the compensatory role of explicit learning mechanisms in children with DLD are, however, scarce, and the few conducted so far have led to inconsistent results. This work aimed to provide new insights into the role that explicit learning mechanisms might play on implicit learning deficits in children with DLD by resorting to a new approach. This approach involved not only the collection of event-related potentials (ERPs), while preschool children with DLD [relative to typical language developmental (TLD) controls] were exposed to a continuous auditory stream made of the repetition of three-syllable nonsense words but, importantly, the collection of ERPs when the same children performed analogous versions of the same auditory SL task first under incidental (implicit) and afterward under intentional (explicit) conditions. In each of these tasks, the level of predictability of the three-syllable nonsense words embedded in the speech streams was also manipulated (high vs. low) to mimic natural languages closely. At the end of both tasks' exposure phase, children performed a two-alternative forced-choice (2-AFC) task from which behavioral evidence of SL was obtained. Results from the 2-AFC tasks failed to show reliable signs of SL in both groups of children. The ERPs data showed, however, significant modulations in the N100 and N400 components, taken as neural signatures of word segmentation in the brain, even though a detailed analysis of the neural responses revealed that only children from the TLD group seem to have taken advantage of the previous knowledge to enhance SL functioning. These results suggest that children with DLD showed deficits both in implicit and explicit learning mechanisms, casting doubts on the efficiency of the interventions relying on explicit instructions to help children with DLD to overcome their language difficulties.
Language	English
Publishing date	2022-06-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.905762
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Article: Quality Characterization of Celery (Apium graveolens L.) by Plant Zones and Two Harvest Dates

Guerra, Natalia / Carrozzi, Liliana / Goñi, María Gabriela / Roura, Sara / Yommi, Alejandra

Journal of food science an official publication of the Institute of Food Technologists. 2010 Aug., v. 75, no. 6

2010

Abstract: The aim of this study was to characterize the quality of celery petioles (Apium graveolens L. cv Golden Clause) from the external, middle, and internal zones of each plant. Harvest dates were 93 (HD1) and 124 (HD2) days after transplantation. Total ... ...

Abstract	The aim of this study was to characterize the quality of celery petioles (Apium graveolens L. cv Golden Clause) from the external, middle, and internal zones of each plant. Harvest dates were 93 (HD1) and 124 (HD2) days after transplantation. Total weight (TW), total length (TL), total leaves number (LN), and petiole length of leaves (PL) for the 3 zones were measured. Physicochemical (color, b* and h; texture; total soluble solids, TSS; titratable acidity, TA; water content, WC), nutraceutical (ascorbic acid, AA; total quinones, TQ; browning potential, BP), and sensorial analysis (flavor, fibrosity, crunchiness) were done at harvest on petioles of each zone. No differences between harvesting dates were found in TW, TL, LN, and PL. Middle leaves had the highest PL. Harvest dates were not different in b*, h, TA, AA, and WC. Texture, TSS, BP, and TQ resulted higher in petioles of HD2 than in HD1. Similar TSS and TA were found in leaves of different plant zones. The yellow color of both external and internal zones was significantly higher than in the middle zone. The texture and BP was similar between the external and middle zones but the WC was lower in the external zone. Similarly, the AA content as well as the TQ was also lower than in the middle zone. Harvest delay improved the nutraceutical value in terms of BP and TQ, even though it also resulted in pithiness and fibrosity of the leaves. This study therefore suggests that the petioles of the middle zone when harvested at HD1 are the most suitable for consumption. Celery is a vegetable reduced in calories, has a high nutritional value and its fresh petioles are mainly consumed in salads. The texture and flavor are the most important attributes that define consumers' acceptability. As nutritional value, texture, and flavor may change with plant age and different zones of the plant, harvest date plays an important role on quality. Results indicate that harvest delay improved the nutraceutical value even though it also resulted in pithiness and fibrosity of the stalks. Petioles of the middle zone, when harvested at 93 d after transplanting, are the most suitable for consumers' consumption.
Keywords	food quality ; celery ; Apium graveolens ; climatic zones ; harvest date ; petioles ; food analysis ; food composition ; nutrient content ; texture
Language	English
Dates of publication	2010-08
Size	p. S327-S332.
Publishing place	Blackwell Publishing Inc
Document type	Article
ZDB-ID	241615-3
ISSN	1750-3841 ; 0022-1147
ISSN (online)	1750-3841
ISSN	0022-1147
DOI	10.1111/j.1750-3841.2010.01701.x
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Article ; Online: Quality characterization of celery (Apium graveolens L.) by plant zones and two harvest dates.

Guerra, Natalia / Carrozzi, Liliana / Goñi, María Gabriela / Roura, Sara / Yommi, Alejandra

Journal of food science

2010 Volume 75, Issue 6, Page(s) S327–32

Abstract	The aim of this study was to characterize the quality of celery petioles (Apium graveolens L. cv Golden Clause) from the external, middle, and internal zones of each plant. Harvest dates were 93 (HD1) and 124 (HD2) days after transplantation. Total weight (TW), total length (TL), total leaves number (LN), and petiole length of leaves (PL) for the 3 zones were measured. Physicochemical (color, b* and h; texture; total soluble solids, TSS; titratable acidity, TA; water content, WC), nutraceutical (ascorbic acid, AA; total quinones, TQ; browning potential, BP), and sensorial analysis (flavor, fibrosity, crunchiness) were done at harvest on petioles of each zone. No differences between harvesting dates were found in TW, TL, LN, and PL. Middle leaves had the highest PL. Harvest dates were not different in b*, h, TA, AA, and WC. Texture, TSS, BP, and TQ resulted higher in petioles of HD2 than in HD1. Similar TSS and TA were found in leaves of different plant zones. The yellow color of both external and internal zones was significantly higher than in the middle zone. The texture and BP was similar between the external and middle zones but the WC was lower in the external zone. Similarly, the AA content as well as the TQ was also lower than in the middle zone. Harvest delay improved the nutraceutical value in terms of BP and TQ, even though it also resulted in pithiness and fibrosity of the leaves. This study therefore suggests that the petioles of the middle zone when harvested at HD1 are the most suitable for consumption. Practical Application: Celery is a vegetable reduced in calories, has a high nutritional value and its fresh petioles are mainly consumed in salads. The texture and flavor are the most important attributes that define consumers' acceptability. As nutritional value, texture, and flavor may change with plant age and different zones of the plant, harvest date plays an important role on quality. Results indicate that harvest delay improved the nutraceutical value even though it also resulted in pithiness and fibrosity of the stalks. Petioles of the middle zone, when harvested at 93 d after transplanting, are the most suitable for consumers' consumption.
MeSH term(s)	Apium graveolens/chemistry ; Apium graveolens/growth & development ; Ascorbic Acid/analysis ; Chemical Phenomena ; Climate ; Crops, Agricultural/chemistry ; Crops, Agricultural/growth & development ; Humans ; Maillard Reaction ; Mechanical Phenomena ; Pigmentation ; Plant Leaves/growth & development ; Plant Stems/chemistry ; Plant Stems/growth & development ; Quality Control ; Quinones/analysis ; Sensation ; Time Factors ; Water/analysis
Chemical Substances	Quinones ; Water (059QF0KO0R) ; Ascorbic Acid (PQ6CK8PD0R)
Language	English
Publishing date	2010-08-01
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	241615-3
ISSN	1750-3841 ; 0022-1147
ISSN (online)	1750-3841
ISSN	0022-1147
DOI	10.1111/j.1750-3841.2010.01701.x
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Article ; Online: Identification and functional characterization of a poly(A)-binding protein from Leishmania infantum (LiPABP).

Guerra, Natalia / Vega-Sendino, María / Pérez-Morgado, M Isabel / Ramos, Edurne / Soto, Manuel / Gonzalez, Víctor M / Martín, M Elena

FEBS letters

2011 Volume 585, Issue 1, Page(s) 193–198

Abstract: Gene expression regulation in Leishmania has been related to post-transcriptional events involving mainly sequences present in the 5' and 3' untranslated regions. PABPs are high-affinity poly(A)-binding proteins that are implicated in the regulation of ... ...

Abstract	Gene expression regulation in Leishmania has been related to post-transcriptional events involving mainly sequences present in the 5' and 3' untranslated regions. PABPs are high-affinity poly(A)-binding proteins that are implicated in the regulation of translation initiation, RNA stability and other important biological processes. We describe a PABP from Leishmania infantum (LiPABP) that shows a very high homology with PABPs from other eukaryotic organisms, including mammals and other parasites. LiPABP conserves the main domains present in other PABPs, maintains poly(A)-binding properties and is phosphorylated by p38 mitogen-activated protein kinase. Using the sera from dogs infected with L. infantum, we demonstrate that LiPABP is expressed in L. infantum promastigotes.
MeSH term(s)	Amino Acid Sequence ; Animals ; Blotting, Western ; Cloning, Molecular ; Cluster Analysis ; Dogs ; HEK293 Cells ; Humans ; Immune Sera/immunology ; Leishmania infantum/genetics ; Leishmania infantum/growth & development ; Leishmania infantum/metabolism ; Molecular Sequence Data ; Phosphorylation ; Phylogeny ; Poly A/genetics ; Poly A/metabolism ; Poly(A)-Binding Proteins/classification ; Poly(A)-Binding Proteins/genetics ; Poly(A)-Binding Proteins/metabolism ; Protozoan Proteins/genetics ; Protozoan Proteins/immunology ; Protozoan Proteins/metabolism ; Sequence Homology, Amino Acid ; p38 Mitogen-Activated Protein Kinases/metabolism
Chemical Substances	Immune Sera ; Poly(A)-Binding Proteins ; Protozoan Proteins ; Poly A (24937-83-5) ; p38 Mitogen-Activated Protein Kinases (EC 2.7.11.24)
Language	English
Publishing date	2011-01-03
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	212746-5
ISSN	1873-3468 ; 0014-5793
ISSN (online)	1873-3468
ISSN	0014-5793
DOI	10.1016/j.febslet.2010.11.042
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Article: Identification and functional characterization of a poly(A)-binding protein from Leishmania infantum (LiPABP)

Guerra, Natalia / Vega-Sendino, María / Pérez-Morgado, M. Isabel / Ramos, Edurne / Soto, Manuel / Gonzalez, Víctor M / Martín, M. Elena

FEBS letters. 2011 Jan. 3, v. 585, no. 1

2011

Abstract: Gene expression regulation in Leishmania has been related to post-transcriptional events involving mainly sequences present in the 5′ and 3′ untranslated regions. PABPs are high-affinity poly(A)-binding proteins that are implicated in the regulation of ... ...

Abstract	Gene expression regulation in Leishmania has been related to post-transcriptional events involving mainly sequences present in the 5′ and 3′ untranslated regions. PABPs are high-affinity poly(A)-binding proteins that are implicated in the regulation of translation initiation, RNA stability and other important biological processes. We describe a PABP from Leishmania infantum (LiPABP) that shows a very high homology with PABPs from other eukaryotic organisms, including mammals and other parasites. LiPABP conserves the main domains present in other PABPs, maintains poly(A)-binding properties and is phosphorylated by p38 mitogen-activated protein kinase. Using the sera from dogs infected with L. infantum, we demonstrate that LiPABP is expressed in L. infantum promastigotes.
Keywords	Leishmania infantum ; RNA ; blood serum ; dog diseases ; gene expression regulation ; mammals ; mitogen-activated protein kinase ; nucleotide sequences ; parasites ; phosphorylation ; promastigotes ; proteins ; sequence homology ; transcription (genetics) ; translation (genetics)
Language	English
Dates of publication	2011-0103
Size	p. 193-198.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	212746-5
ISSN	1873-3468 ; 0014-5793
ISSN (online)	1873-3468
ISSN	0014-5793
DOI	10.1016/j.febslet.2010.11.042
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Article: Calpain inhibition stimulates caspase-dependent apoptosis induced by taxol in NIH3T3 cells.

Piñeiro, David / Martín, M Elena / Guerra, Natalia / Salinas, Matilde / González, Víctor M

Experimental cell research

2006 Volume 313, Issue 2, Page(s) 369–379

Abstract: Taxol is an anticancer drug that triggers apoptosis in a wide spectrum of cancers such as ovarian, breast, lung, head and neck, and bladder carcinoma by both caspase-dependent and -independent apoptosis mechanisms. However, the exact signaling pathways ... ...

Abstract	Taxol is an anticancer drug that triggers apoptosis in a wide spectrum of cancers such as ovarian, breast, lung, head and neck, and bladder carcinoma by both caspase-dependent and -independent apoptosis mechanisms. However, the exact signaling pathways involved in taxol-induced apoptosis strongly depend on the cellular background and they are not completely established yet. In this study we demonstrate that taxol induces caspase-3-independent apoptosis in NIH3T3 cells by a calpain-mediated mechanism. Taxol treatment produced changes in the mitochondrial membrane potential (Delta Psi m) which could be responsible of Ca(2+) release from the mitochondria and the consequent calpain activation. Interestingly, we show that calpain produced proteolysis of caspase-3 and demonstrate that, accordingly, calpain inhibition increased taxol-induced apoptosis. In addition, we reveal that poly (ADP-ribose) polymerase (PARP) was processed by calpain in taxol-treated cells and by caspase-3 after calpain inhibition. In conclusion, these results demonstrate for the first time that calpain could play an important role modulating taxol-induced apoptosis. Further studies are needed to address the potentiality of inducing apoptosis by a combined use of taxol and calpain inhibitors in cells with increased calpain activity.
MeSH term(s)	Animals ; Antineoplastic Agents, Phytogenic/pharmacology ; Apoptosis/drug effects ; Calcium/analysis ; Calcium/metabolism ; Calpain/antagonists & inhibitors ; Calpain/physiology ; Caspase 3/physiology ; Caspase Inhibitors ; Cysteine Proteinase Inhibitors/pharmacology ; Cytoplasm/chemistry ; Cytoplasm/metabolism ; Dipeptides/pharmacology ; Membrane Potential, Mitochondrial/drug effects ; Mice ; NIH 3T3 Cells ; Paclitaxel/pharmacology
Chemical Substances	Antineoplastic Agents, Phytogenic ; Caspase Inhibitors ; Cysteine Proteinase Inhibitors ; Dipeptides ; Calpain (EC 3.4.22.-) ; Caspase 3 (EC 3.4.22.-) ; Paclitaxel (P88XT4IS4D) ; Calcium (SY7Q814VUP) ; calpain inhibitor III (WCJ9LQ197S)
Language	English
Publishing date	2006-10-26
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1493-x
ISSN	1090-2422 ; 0014-4827
ISSN (online)	1090-2422
ISSN	0014-4827
DOI	10.1016/j.yexcr.2006.10.020
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Article: Natural killer receptors on CD8 T cells and natural killer cells from different HLA-C phenotypes in melanoma patients.

Campillo, José A / Martínez-Escribano, Jorge A / Moya-Quiles, M Rosa / Marín, Luis A / Muro, Manuel / Guerra, Natalia / Parrado, Antonio / Campos, Matilde / Frías, José F / Minguela, Alfredo / García-Alonso, Ana M / Alvarez-López, María Rocío

Clinical cancer research : an official journal of the American Association for Cancer Research

2006 Volume 12, Issue 16, Page(s) 4822–4831

Abstract: Purpose: Because immune mechanisms involved in cutaneous melanoma have not been fully elucidated, efforts have been made to achieve prognosis markers and potential targets for immune therapies, but they have not been entirely fruitful thus far. ... ...

Abstract	Purpose: Because immune mechanisms involved in cutaneous melanoma have not been fully elucidated, efforts have been made to achieve prognosis markers and potential targets for immune therapies, but they have not been entirely fruitful thus far. Therefore, the goal of this study was to investigate the involvement of early changes in CD8 T cells and CD56 natural killer (NK) cells expressing NK receptors in different HLA-C dimorphism groups of melanoma patients. Experimental design: CD8 T cells and CD56 NK cells were analyzed in 41 patients and 39 sex- and age-matched controls with different HLA-C genotypes by flow cytometry. HLA-C dimorphism at position 80 was tested by PCR sequence-specific primers and PCR sequence-specific oligonucleotide to examine whether it could mediate in the emergence of cells expressing killer cell immunoglobulin-like receptors. Results: Thirty-five of 41 patients had benign sentinel node, and showed an imbalance in the absolute number of CD8(+)DR(+) or CD8(+)CD161(+) peripheral blood T cells according to the CD28 coexpression compared with controls. CD8(+)CD28(-)CD158a(+) T and CD56(+)CD158a(+) NK cells were significantly increased in HLA-C(Lys80) homozygous nonmetastatic patients, whereas only CD56(+)CD158a(+) NK cells increased in heterozygous ones. An up-regulation of the CD158a KIR receptor was also seen on NK cells but not in T cells of patients at advanced disease stages. Conclusions: This work provides, for the first time, evidence of immune activation in early stages of cutaneous melanoma, together with an increase of cells expressing CD158a in patients bearing the corresponding HLA-C ligand, which may be important to evaluate the disease progression and to use individualized immune therapeutic approaches.
MeSH term(s)	Adult ; Aged ; Antigens, Differentiation, T-Lymphocyte/immunology ; CD56 Antigen/immunology ; CD8-Positive T-Lymphocytes/immunology ; Female ; HLA-C Antigens/immunology ; Humans ; Killer Cells, Natural/immunology ; Male ; Melanoma/immunology ; Middle Aged ; Receptors, Immunologic/immunology ; Receptors, KIR ; Receptors, KIR2DL1 ; Skin Neoplasms/immunology
Chemical Substances	Antigens, Differentiation, T-Lymphocyte ; CD56 Antigen ; HLA-C Antigens ; Receptors, Immunologic ; Receptors, KIR ; Receptors, KIR2DL1
Language	English
Publishing date	2006-08-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1225457-5
ISSN	1557-3265 ; 1078-0432
ISSN (online)	1557-3265
ISSN	1078-0432
DOI	10.1158/1078-0432.CCR-06-0019
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Article: HLA class I and class II frequencies in patients with cutaneous malignant melanoma from southeastern Spain: the role of HLA-C in disease prognosis.

Campillo, José A / Martínez-Escribano, Jorge A / Muro, Manuel / Moya-Quiles, Rosa / Marín, Luis A / Montes-Ares, Olga / Guerra, Natalia / Sánchez-Pedreño, Paloma / Frías, José F / Lozano, José A / García-Alonso, Ana M / Alvarez-López, M Rocío

Immunogenetics

2006 Volume 57, Issue 12, Page(s) 926–933

Abstract: Available data have led to a controversy on the relationship between human leukocyte antigen (HLA) and cutaneous malignant melanoma susceptibility or prognosis. Moreover, the influence of HLA-C on melanoma has not yet been well established. Therefore, ... ...

Abstract	Available data have led to a controversy on the relationship between human leukocyte antigen (HLA) and cutaneous malignant melanoma susceptibility or prognosis. Moreover, the influence of HLA-C on melanoma has not yet been well established. Therefore, the aim of the current study was to analyze the possible influence of the HLA system on melanoma susceptibility and prognosis in the Spanish population. For this purpose, HLA-A and HLA-B serotyping and HLA-C, HLA-DRB1, and HLA-DQB1 genotyping by polymerase chain reactions using sequence-specific oligonucleotide (PCR-SSO) and sequence-specific primer (PCR-SSP) were performed in 174 melanoma patients and 227 ethnically matched controls. The number of controls was increased up to 356 for HLA-C typing. Patients were stratified according to the histological subtypes of melanoma, sentinel lymph node status, tumor thickness, and ulceration of primary lesion. No HLA-A, HLA-B, HLA-DRB1, or HLA-DQB1 relationship with melanoma was observed for susceptibility or disease prognosis. However, the analysis of HLA-C locus showed that individuals homozygous for HLA-C(Lys80) were significantly more frequent within the patient than the control group. Remarkably, individuals homozygous for group 2 HLA-C alleles (HLA-C(Lys80)) seem to be associated with metastatic progression of melanoma. In contrast, we found a negative association between group 1 HLA-C alleles (HLA-C(Asn80)) and disease susceptibility or metastasis development. In conclusion, although an association with HLA-A, HLA-B, HLA-DRB1, or HLA-DQB1 was not demonstrated, the study of the HLA-C locus revealed that the analysis of the dimorphism at position 80 in the alpha1 helix may help to evaluate the risk and prognosis of melanoma in our population.
MeSH term(s)	Case-Control Studies ; Female ; Gene Frequency ; Genes, MHC Class I ; Genes, MHC Class II ; HLA-C Antigens/genetics ; Humans ; Lymphatic Metastasis ; Male ; Melanoma/genetics ; Melanoma/immunology ; Melanoma/secondary ; Phenotype ; Prognosis ; Skin Neoplasms/genetics ; Skin Neoplasms/immunology ; Spain
Chemical Substances	HLA-C Antigens
Language	English
Publishing date	2006-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	186560-2
ISSN	1432-1211 ; 0093-7711
ISSN (online)	1432-1211
ISSN	0093-7711
DOI	10.1007/s00251-005-0065-2
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Article: Identification and functional characterization of a poly(A)-binding protein from Leishmania infantum (LiPABP)

Guerra, Natalia / Vega-Sendino, María / Pérez-Morgado, M. Isabel / Ramos, Edurne / Soto, Manuel / Gonzalez, Víctor M. / Martín, M. Elena

FEBS letters

Volume v. 585,, Issue no. 1

Abstract	Gene expression regulation in Leishmania has been related to post-transcriptional events involving mainly sequences present in the 5′ and 3′ untranslated regions. PABPs are high-affinity poly(A)-binding proteins that are implicated in the regulation of translation initiation, RNA stability and other important biological processes. We describe a PABP from Leishmania infantum (LiPABP) that shows a very high homology with PABPs from other eukaryotic organisms, including mammals and other parasites. LiPABP conserves the main domains present in other PABPs, maintains poly(A)-binding properties and is phosphorylated by p38 mitogen-activated protein kinase. Using the sera from dogs infected with L. infantum, we demonstrate that LiPABP is expressed in L. infantum promastigotes.
Keywords	blood serum ; mammals ; parasites ; promastigotes ; mitogen-activated protein kinase ; transcription (genetics) ; gene expression regulation ; dog diseases ; translation (genetics) ; Leishmania infantum ; RNA ; sequence homology ; nucleotide sequences ; phosphorylation ; proteins
Language	English
Document type	Article
ISSN	0014-5793
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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