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  1. Article ; Online: Tailored TPT for drug-resistant TB - promoting equity and access to optimal care.

    Khan, U / Guglielmetti, L

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2023  Volume 27, Issue 1, Page(s) 89b–90

    MeSH term(s) Humans ; Tuberculosis, Multidrug-Resistant/drug therapy ; Health Services Accessibility ; Healthcare Disparities
    Language English
    Publishing date 2023-03-30
    Publishing country France
    Document type Letter ; Comment
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.22.0538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evidence and ethical considerations for the treatment of contacts exposed to drug-resistant TB.

    Khan, U / Guglielmetti, L

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2022  Volume 26, Issue 9, Page(s) 900–901

    MeSH term(s) Antitubercular Agents/therapeutic use ; Contact Tracing ; Humans ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Multidrug-Resistant/epidemiology
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2022-08-19
    Publishing country France
    Document type Letter ; Comment
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.22.0328
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Relative cost of multidrug-resistant TB medicines in Europe.

    Günther, G / Guglielmetti, L / Leu, C / van Leth, F / Lange, C

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2023  Volume 27, Issue 5, Page(s) 341–344

    MeSH term(s) Humans ; Antitubercular Agents/therapeutic use ; Tuberculosis, Multidrug-Resistant/drug therapy ; Europe
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2023-05-04
    Publishing country France
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.23.0026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Avancées dans l’antibiothérapie de la tuberculose.

    Maitre, Thomas / Guglielmetti, Lorenzo / Robert, Jérôme / Aubry, Alexandra / Veziris, Nicolas

    La Revue du praticien

    2024  Volume 74, Issue 3, Page(s) 239–244

    Abstract: ADVANCES IN ANTIBIOTIC THERAPY FOR TUBERCULOSIS. Treatment of tuberculosis is experiencing significant advancements. For the first time, a therapeutic regimen based on rifapentine and moxifloxacin allows for a reduction of treatment duration of drug- ... ...

    Title translation Advances in antibiotic therapy for tuberculosis.
    Abstract ADVANCES IN ANTIBIOTIC THERAPY FOR TUBERCULOSIS. Treatment of tuberculosis is experiencing significant advancements. For the first time, a therapeutic regimen based on rifapentine and moxifloxacin allows for a reduction of treatment duration of drug-susceptible tuberculosis from 6 to 4 months. Regarding multidrug-resistant tuberculosis, combinations of new antituberculosis drugs (bedaquiline, linezolid, delamanid/pretomanid, moxifloxacin) have the potential to reduce the treatment duration from 20 to 6 months. Additionally, considering the extent of anatomical involvement and bacterial burden allows for strategies that involve variable treatment durations based on the severity of the disease. The new tuberculosis treatments thus appear to be shorter and more personalized.
    MeSH term(s) Humans ; Antitubercular Agents/therapeutic use ; Moxifloxacin/therapeutic use ; Tuberculosis/drug therapy ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Multidrug-Resistant/microbiology ; Linezolid/therapeutic use ; Mycobacterium tuberculosis
    Chemical Substances Antitubercular Agents ; Moxifloxacin (U188XYD42P) ; Linezolid (ISQ9I6J12J)
    Language French
    Publishing date 2024-03-28
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Bedaquiline for the treatment of multidrug-resistant tuberculosis: another missed opportunity?

    Guglielmetti, Lorenzo

    The European respiratory journal

    2017  Volume 49, Issue 5

    MeSH term(s) Antitubercular Agents ; Diarylquinolines ; Humans ; Tuberculosis, Multidrug-Resistant
    Chemical Substances Antitubercular Agents ; Diarylquinolines ; bedaquiline (78846I289Y)
    Language English
    Publishing date 2017
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.00738-2017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Optimal management of drug-resistant tuberculosis: Can India lead the way?

    Masini, Tiziana / Furin, Jennifer / Udwadia, Zarir / Guglielmetti, Lorenzo

    The Indian journal of medical research

    2023  Volume 157, Issue 2&3, Page(s) 220–222

    MeSH term(s) Humans ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Multidrug-Resistant/epidemiology ; Antitubercular Agents/therapeutic use ; India/epidemiology ; Mycobacterium tuberculosis ; Microbial Sensitivity Tests
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2023-05-18
    Publishing country India
    Document type Journal Article
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.ijmr_300_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cardiac safety of multidrug-resistant tuberculosis treatment: moving towards individualised monitoring.

    Hewison, Catherine / Guglielmetti, Lorenzo

    The Lancet. Infectious diseases

    2021  Volume 21, Issue 7, Page(s) 894–895

    MeSH term(s) Antitubercular Agents/adverse effects ; Humans ; Tuberculosis, Multidrug-Resistant/drug therapy
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2021-02-12
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30836-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The coming-of-age of bedaquiline: a tale with an open ending.

    Guglielmetti, Lorenzo / Varaine, Francis

    The European respiratory journal

    2021  Volume 57, Issue 6

    MeSH term(s) Diarylquinolines ; Humans ; Tuberculosis, Multidrug-Resistant
    Chemical Substances Diarylquinolines ; bedaquiline (78846I289Y)
    Language English
    Publishing date 2021-06-10
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.00066-2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Reply to: "Human rights: finding the right balance for rifampicin-resistant TB treatment".

    Cox, V / Guglielmetti, L / Hewison, C / Reuter, A / Furin, J

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2021  Volume 25, Issue 4, Page(s) 328–329

    MeSH term(s) Antibiotics, Antitubercular/therapeutic use ; Human Rights ; Humans ; Rifampin ; Tuberculosis, Multidrug-Resistant/drug therapy
    Chemical Substances Antibiotics, Antitubercular ; Rifampin (VJT6J7R4TR)
    Language English
    Publishing date 2021-03-25
    Publishing country France
    Document type Letter ; Comment
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.21.0006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Preventive Therapy for Contacts of Drug-Resistant Tuberculosis.

    Kherabi, Yousra / Tunesi, Simone / Kay, Alexander / Guglielmetti, Lorenzo

    Pathogens (Basel, Switzerland)

    2022  Volume 11, Issue 10

    Abstract: Preventing the progression of a drug-resistant tuberculosis (DR-TB) infection to disease is an important pillar of the DR-TB elimination strategy. International guidelines have recently proposed fluoroquinolones for tuberculosis preventive therapy (TPT) ... ...

    Abstract Preventing the progression of a drug-resistant tuberculosis (DR-TB) infection to disease is an important pillar of the DR-TB elimination strategy. International guidelines have recently proposed fluoroquinolones for tuberculosis preventive therapy (TPT) in DR-TB contacts, although the available evidence is low quality. The pooled data from small observational studies suggest that a fluoroquinolone-based TPT is safe, effective and cost-effective as a preventive treatment in DR-TB contacts. Three clinical trials are currently ongoing to generate higher quality evidence on the efficacy of levofloxacin and delamanid as a DR-TB preventive therapy. Additional evidence is also needed, regarding TPT treatment in fluoroquinolone-resistant-TB contacts, patient and health care worker perceptions on DR-TB preventive therapy for contacts, and the service delivery models to increase DR-TPT access. This state-of-the-art review presents the current literature on TPT for contacts of DR-TB cases, focusing on the available evidence and international guidelines.
    Language English
    Publishing date 2022-10-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens11101189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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