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  1. Article ; Online: One-step uranium extraction and brine desalination via adsorptive pervaporation by graphene-oxide scaffold membranes.

    Wang, Guangcheng / Shi, Gui Min / Zhang, Sui

    Journal of hazardous materials

    2023  Volume 457, Page(s) 131822

    Abstract: The ocean reserves nearly four billion tons of uranium, providing an inexhaustible supply of nuclear energy if the limits of ultralow U(VI) concentration (3.3 µg· ... ...

    Abstract The ocean reserves nearly four billion tons of uranium, providing an inexhaustible supply of nuclear energy if the limits of ultralow U(VI) concentration (3.3 µg·L
    Language English
    Publishing date 2023-06-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.131822
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: One-step uranium extraction and brine desalination via adsorptive pervaporation by graphene-oxide scaffold membranes

    Wang, Guangcheng / Shi, Gui Min / Zhang, Sui

    Journal of Hazardous Materials. 2023 Sept., v. 457, p. 131822

    2023  , Page(s) 131822

    Abstract: The ocean reserves nearly four billion tons of uranium, providing an inexhaustible supply of nuclear energy if the limits of ultralow U(VI) concentration (3.3 µg·L⁻¹) are addressed. Membrane technology is promising to make this happen by simultaneous U( ... ...

    Abstract The ocean reserves nearly four billion tons of uranium, providing an inexhaustible supply of nuclear energy if the limits of ultralow U(VI) concentration (3.3 µg·L⁻¹) are addressed. Membrane technology is promising to make this happen by simultaneous U(VI) concentration and extraction. Herein, we report a pioneering adsorption-pervaporation membrane for efficient enrichment and capture of U(VI) along with clean water production. A bifunctional poly(dopamine–ethylenediamine) and graphene oxide 2D scaffold membrane was developed and further crosslinked by glutaraldehyde, capable of recovering over 70% U(VI) and water from simulated seawater brine, which validates the feasibility of one-step water recovery, brine concentration, and uranium extraction from seawater brine. Moreover, compared with other membranes and adsorbents, this membrane exhibits fast pervaporation desalination (flux: 153.3 kg·m⁻²·h⁻¹, rejection: >99.99%) and excellent uranium capture properties of 228.6 mg·m⁻² benefiting from plentiful functional groups provided by embedded poly(dopamine–ethylenediamine). This study aims to provide a strategy for recovering critical elements from the ocean.
    Keywords adsorbents ; crosslinking ; desalination ; glutaraldehyde ; graphene oxide ; nuclear power ; pervaporation ; seawater ; uranium ; Adsorption ; Seawater brine
    Language English
    Dates of publication 2023-09
    Size p. 131822
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.131822
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Study on medication rules of traditional Chinese medicine for Meniere's disease based on data analysis

    Hui-Jie Zhang / Gui-Min Chen

    Journal of Hainan Medical University, Vol 28, Iss 7, Pp 58-

    2022  Volume 64

    Abstract: Objective: Study on medication rules of traditional Chinese medicine in treating Meniere 's disease based on data mining technology. Methods: Computer retrieval with since establishment of the“CNKI”, “WF”, “VIP”, there have been literatures on the ... ...

    Abstract Objective: Study on medication rules of traditional Chinese medicine in treating Meniere 's disease based on data mining technology. Methods: Computer retrieval with since establishment of the“CNKI”, “WF”, “VIP”, there have been literatures on the treatment of Meniere syndrome with Traditional Chinses medicine. Memory preprocessing in accordance with inclusion criteria. Then, EXCLE 2010, SPSS Statistics (ver. 25) and SPSS Modeler (ver. 18.0) were adopted respectively for frequency analysis, cluster analysis and association rules analysis. Result: A total of 133 references were included in this study, 146 prescriptions, 192 kinds of drugs, and the total frequency of drugs was 1702. The high frequency Meniere syndrome types were spleen deficiency and phlegm dampness syndrome, wind phlegm syndrome, gallbladder depression and phlegm disturbance syndrome, hyperactivity of liver yang syndrome, phlegm and blood stasis syndrome. The efficacy of drug frequency ≥ 25 were summarized as follows, antiasthmatic drugs for relieving phlegm and relieving cough, diuresisremoving dampness, Tonic drugs, etc. High frequency meridian of drugs are: lung, liver, spleen, etc. High frequency drug properties are: temperature, cold, flat etc. High frequency drug taste: bitter, sweet, pungent, etc. Core drugs: Pinellia, Atractylodes, Poria, Gastrodia, etc. The main prescriptions werealisma soup, Banxia Baizhu Tianma Decoction, Zhengan Xifeng Decoction and Xiaochaihu Decoction. Conclusion: In this study, data mining was used to sort out the treatment of Meniere ' s disease by traditional Chinese medicine. It was found that the treatment of Meniere ' s disease was mainly to calm the liver and strengthen the spleen, supplemented by regulating qi and activating blood, clearing heat and opening orifices, tonifying deficiency and tranquilizing mind.
    Keywords meniere's disease ; medication rule ; vertigo ; medication law ; data analysis ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Editorial Board of Journal of Hainan Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Metabolism in Cancer Stem Cells

    Gui-Min Wen / Xiao-Yan Xu / Pu Xia

    Cells, Vol 11, Iss 3790, p

    Targets for Clinical Treatment

    2022  Volume 3790

    Abstract: Cancer stem cells (CSCs) have high tumorigenicity, high metastasis and high resistance to treatment. They are the key factors for the growth, metastasis and drug resistance of malignant tumors, and are also the important reason for the occurrence and ... ...

    Abstract Cancer stem cells (CSCs) have high tumorigenicity, high metastasis and high resistance to treatment. They are the key factors for the growth, metastasis and drug resistance of malignant tumors, and are also the important reason for the occurrence and recurrence of tumors. Metabolic reprogramming refers to the metabolic changes that occur when tumor cells provide sufficient energy and nutrients for themselves. Metabolic reprogramming plays an important role in regulating the growth and activity of cancer cells and cancer stem cells. In addition, the immune cells or stromal cells in the tumor microenvironment (TME) will change due to the metabolic reprogramming of cancer cells. Summarizing the characteristics and molecular mechanisms of metabolic reprogramming of cancer stem cells will provide new ideas for the comprehensive treatment of malignant tumors. In this review, we summarized the changes of the main metabolic pathways in cancer cells and cancer stem cells.
    Keywords metabolism ; cancer stem cell ; ALDH1 ; ferroptosis ; tumor microenvironment ; Biology (General) ; QH301-705.5
    Subject code 610 ; 570
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: ASO Author Reflections: Tumor Marker Score Based on Conventional Tumor Markers (AFP, CEA, and CA19-9) Predicts Prognosis Well for cHCC-CC Patients After Surgery.

    Hou, Gui-Min / Zeng, Yong

    Annals of surgical oncology

    2021  Volume 28, Issue 12, Page(s) 7661–7662

    MeSH term(s) Biomarkers, Tumor ; CA-19-9 Antigen ; Carcinoembryonic Antigen ; Humans ; Liver Neoplasms ; Prognosis ; alpha-Fetoproteins
    Chemical Substances Biomarkers, Tumor ; CA-19-9 Antigen ; Carcinoembryonic Antigen ; alpha-Fetoproteins
    Language English
    Publishing date 2021-04-24
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-021-09983-z
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4042: Show issues Location:
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  6. Article: Different races have different immune microenvironments: comparison of White and Asian patients with liver cancer.

    Wen, Gui-Min / Song, Chang-Liang / Liu, Da-Hua / Xia, Pu

    American journal of cancer research

    2023  Volume 13, Issue 3, Page(s) 1118–1127

    Abstract: Different ethnic groups have different incidence rate of hepatocellular carcinoma (HCC). In addition to lifestyle and environmental factors, genetic susceptibility is also an important reason. In this study, we screened the immune related genes and ... ...

    Abstract Different ethnic groups have different incidence rate of hepatocellular carcinoma (HCC). In addition to lifestyle and environmental factors, genetic susceptibility is also an important reason. In this study, we screened the immune related genes and stromal related genes in White and Asian liver cancer patients cohort of The Cancer Genome Atlas (TCGA) the using ESTIMATE algorithm. Hub genes that significantly associated with overall survival (OS) were selected from White and Asian liver cancer patients, respectively. In addition, we validated the functions of two hub genes, IL-18RAP and GPM6A,
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2589522-9
    ISSN 2156-6976
    ISSN 2156-6976
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  7. Article: Differences of ferroptosis-related genes between White and Asian patients with liver cancer.

    Xia, Pu / Wen, Gui-Min / Zheng, Xiao-Hui / Zhao, Zhen-Ying

    American journal of cancer research

    2023  Volume 13, Issue 8, Page(s) 3659–3667

    Abstract: Ferroptosis results from metabolic dysregulation and is closely linked to liver cancer. Although a ferroptosis-related gene signature in liver cancer has been established, the precise regulatory mechanism is still unclear. To identify shared pathogenic ... ...

    Abstract Ferroptosis results from metabolic dysregulation and is closely linked to liver cancer. Although a ferroptosis-related gene signature in liver cancer has been established, the precise regulatory mechanism is still unclear. To identify shared pathogenic genes linked to ferroptosis across liver cancer patients from diverse racial backgrounds, we evaluated various ferroptosis-related genes, constructing a signature for both Asian and White patients using The Cancer Genome Atlas (TCGA) database. Based on the differential expression and functionality of ferroptosis-associated genes, we selected Farnesyl diphosphate farnesyl transferase 1 (FDFT1), Acyl-CoA synthetase long-chain 4 (ACSL4) and Endoplasmic reticulum membrane protein complex 2 (EMC2) for further study in liver cancer cells. FDFT1, ACSL4 and EMC2 induced ferroptosis of liver cancer cells though upregulation of reactive oxygen species (ROS) levels and downregulation of glutathione peroxidase (GPX4). Current data indicate no notable influence of racial differences on the functionality of ferroptosis-related genes. Our data suggests potential novel therapeutic avenues for liver cancer treatment.
    Language English
    Publishing date 2023-08-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2589522-9
    ISSN 2156-6976
    ISSN 2156-6976
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  8. Article ; Online: Ectopic thyroid of the pancreatic head: A case report.

    Hou, Gui-Min / Qin, Fang-Yin / He, Yong-Jie / Feng, Xie-Lin

    Asian journal of surgery

    2023  Volume 46, Issue 7, Page(s) 2970–2971

    MeSH term(s) Humans ; Thyroid Dysgenesis/diagnostic imaging ; Thyroid Dysgenesis/surgery
    Language English
    Publishing date 2023-03-09
    Publishing country Netherlands
    Document type Case Reports ; Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.02.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2831: Show issues Location:
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  9. Article ; Online: Effect of secretory DKK3 on circulating CD56

    Liu, Da-Hua / Wen, Gui-Min / Song, Chang-Liang / Xia, Pu

    The International journal of biological markers

    2023  Volume 38, Issue 2, Page(s) 99–104

    Abstract: Background: Liver cancer seriously threatens human health. Natural killer (NK) cells are an important part of the innate immune system and have strong anti-tumor ability. Immunotherapy based on NK cells has become a hot topic in the treatment of liver ... ...

    Abstract Background: Liver cancer seriously threatens human health. Natural killer (NK) cells are an important part of the innate immune system and have strong anti-tumor ability. Immunotherapy based on NK cells has become a hot topic in the treatment of liver cancer.
    Methods: In this study, we checked the serum DKK3 (sDKK3) and circulating CD56
    Results: We found low levels of sDKK3 in liver cancer patients and a negative correlation between sDKK3 and circulating CD56
    Conclusions: Improving the clinical efficacy of NK cells through DKK3 will become a new strategy for cancer immunotherapy.
    MeSH term(s) Humans ; CD56 Antigen ; Killer Cells, Natural/metabolism ; Killer Cells, Natural/pathology ; Liver Neoplasms/therapy ; Liver Neoplasms/pathology ; Flow Cytometry ; Cell Differentiation ; Adaptor Proteins, Signal Transducing
    Chemical Substances CD56 Antigen ; DKK3 protein, human ; Adaptor Proteins, Signal Transducing
    Language English
    Publishing date 2023-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645113-5
    ISSN 1724-6008 ; 0393-6155
    ISSN (online) 1724-6008
    ISSN 0393-6155
    DOI 10.1177/03936155231169796
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2491: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  10. Article ; Online: Metabolism in Cancer Stem Cells: Targets for Clinical Treatment.

    Wen, Gui-Min / Xu, Xiao-Yan / Xia, Pu

    Cells

    2022  Volume 11, Issue 23

    Abstract: Cancer stem cells (CSCs) have high tumorigenicity, high metastasis and high resistance to treatment. They are the key factors for the growth, metastasis and drug resistance of malignant tumors, and are also the important reason for the occurrence and ... ...

    Abstract Cancer stem cells (CSCs) have high tumorigenicity, high metastasis and high resistance to treatment. They are the key factors for the growth, metastasis and drug resistance of malignant tumors, and are also the important reason for the occurrence and recurrence of tumors. Metabolic reprogramming refers to the metabolic changes that occur when tumor cells provide sufficient energy and nutrients for themselves. Metabolic reprogramming plays an important role in regulating the growth and activity of cancer cells and cancer stem cells. In addition, the immune cells or stromal cells in the tumor microenvironment (TME) will change due to the metabolic reprogramming of cancer cells. Summarizing the characteristics and molecular mechanisms of metabolic reprogramming of cancer stem cells will provide new ideas for the comprehensive treatment of malignant tumors. In this review, we summarized the changes of the main metabolic pathways in cancer cells and cancer stem cells.
    Language English
    Publishing date 2022-11-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells11233790
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