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  1. AU="Guiducci, Laura"
  2. AU=Chaudhry Imtiaz A
  3. AU="Baoqing Sun"
  4. AU="Pereira, A A"
  5. AU="Graff, Nicholas R"
  6. AU=Jones Jana E
  7. AU=Takabayashi Akinobu
  8. AU="Paratz, Jennifer D"
  9. AU="Schulte, Kevin L."
  10. AU="Hu, Guanqun"
  11. AU="Li, Jin-Yan"
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  1. Article ; Online: Dendritic cells in reflectance confocal microscopy are a clue for early melanoma diagnosis in extrafacial flat pigmented melanocytic lesions.

    Guiducci, Laura / Kaleci, Shaniko / Chester, Johanna / Longo, Caterina / Ciardo, Silvana / Farnetani, Francesca / Pellacani, Giovanni

    Experimental dermatology

    2022  Volume 31, Issue 7, Page(s) 1048–1055

    Abstract: Differential diagnosis of extrafacial flat pigmented lesions with dermoscopic reticular and/or homogeneous pattern is challenging. Dendritic cells upon reflectance confocal microscopy (RCM) still represent a pitfall. This study aims to determine the role ...

    Abstract Differential diagnosis of extrafacial flat pigmented lesions with dermoscopic reticular and/or homogeneous pattern is challenging. Dendritic cells upon reflectance confocal microscopy (RCM) still represent a pitfall. This study aims to determine the role of dendritic cells upon RCM in the epidermis and dermo-epidermal junction (DEJ), together with common RCM features for melanoma and nevi, in dermoscopically equivocal extrafacial flat pigmented lesions. A retrospective evaluation of RCM images of melanocytic extrafacial flat pigmented lesions with reticular and/or homogeneous dermoscopic pattern and with histopathological diagnosis, was performed. A multivariate model of RCM features was used to obtain a score of independent risk factors. A total of 698 lesions were included. Increasing patient age, epidermal dendritic cells, many dendritic cells in the DEJ (>30%) and many (>5/mm
    MeSH term(s) Dendritic Cells ; Dermoscopy/methods ; Diagnosis, Differential ; Humans ; Melanoma/pathology ; Microscopy, Confocal/methods ; Nevus/diagnosis ; Retrospective Studies ; Skin Neoplasms/pathology
    Language English
    Publishing date 2022-03-04
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1130936-2
    ISSN 1600-0625 ; 0906-6705
    ISSN (online) 1600-0625
    ISSN 0906-6705
    DOI 10.1111/exd.14553
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3508: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Treatment monitoring of 5-fluorouracil 0.5%/salicylic acid 10% lesion-directed therapy for actinic keratosis using dermoscopy and in-vivo reflectance confocal microscopy.

    Pampena, Riccardo / Condorelli, Alessandra / Cornacchia, Luigi / Guiducci, Laura / Raucci, Margherita / Benati, Elisa / Mirra, Marica / Peris, Ketty / Lai, Michela / Pellacani, Giovanni / Longo, Caterina

    Dermatologic therapy

    2020  Volume 33, Issue 4, Page(s) e13744

    Abstract: Recently, 5-fluorouracil 0.5%/salicylic acid 10% (5-FU/SA) topical solution has been included in the National Italian portfolio for lesion-directed treatment of grade I/II actinic keratosis (AKs) located on the face or scalp. To describe the utility of ... ...

    Abstract Recently, 5-fluorouracil 0.5%/salicylic acid 10% (5-FU/SA) topical solution has been included in the National Italian portfolio for lesion-directed treatment of grade I/II actinic keratosis (AKs) located on the face or scalp. To describe the utility of dermoscopy and RCM in treatment response monitoring of a series of AKs treated with 5-FU/SA as lesion-directed therapy. Consecutive patients were prospectively treated for a maximum of 12 weeks with 5-FU/SA for AKs located on the face or scalp. Clinical, dermoscopic, and confocal images of one index AK were acquired at each visit and pre-specified criteria were evaluated. Clinical, dermoscopic, and confocal responses were evaluated at last follow-up visit. Fourteen patients were enrolled, of which five were treated for 12 weeks, seven for 8, and two for 4 weeks. At a median follow up of 30 weeks, 64.3% (9/14) index AKs achieved complete clinical, 50% (7/14) complete dermoscopic and 42.9% (6/14) complete confocal clearance. Local skin reaction was mild and significantly decreased during therapy administration. Although the small number of cases, our study underlines the utility of both dermoscopy and in-vivo RCM in 5-FU/SA treatment response monitoring for AKs located on the face or scalp.
    MeSH term(s) Dermoscopy ; Fluorouracil ; Humans ; Keratosis, Actinic/diagnostic imaging ; Keratosis, Actinic/drug therapy ; Microscopy, Confocal ; Salicylic Acid
    Chemical Substances Salicylic Acid (O414PZ4LPZ) ; Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2020-07-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13744
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5181: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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