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  1. Article ; Online: Distinct Predictors of Clinical Response after Repetitive Transcranial Magnetic Stimulation between Bipolar and Unipolar Disorders.

    Lacroix, Aurélie / Paquet, Aude / Okassa, Mireille / Vinais, Théodore / Lannaud, Marilyne / Plansont, Brigitte / Buisson, Alexandre / Guignandon, Sandrine / Malauzat, Dominique / Girard, Murielle / Calvet, Benjamin

    International journal of environmental research and public health

    2023  Volume 20, Issue 7

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Transcranial Magnetic Stimulation/methods ; Bipolar Disorder/therapy ; Anxiety Disorders ; Treatment Outcome ; Prefrontal Cortex
    Language English
    Publishing date 2023-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20075276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Predictors of clinical response after rTMS treatment of patients suffering from drug-resistant depression.

    Lacroix, Aurélie / Calvet, Benjamin / Laplace, Benjamin / Lannaud, Marilyne / Plansont, Brigitte / Guignandon, Sandrine / Balestrat, Patrice / Girard, Murielle

    Translational psychiatry

    2021  Volume 11, Issue 1, Page(s) 587

    Abstract: Repeated transcranial magnetic stimulation (rTMS) is a therapeutic brain-stimulation technique that is particularly used for drug-resistant depressive disorders. European recommendations mention the effectiveness of 30 to 64%. The failure rate of ... ...

    Abstract Repeated transcranial magnetic stimulation (rTMS) is a therapeutic brain-stimulation technique that is particularly used for drug-resistant depressive disorders. European recommendations mention the effectiveness of 30 to 64%. The failure rate of treatment is high and clinical improvement is visible only after a certain period of time. It would thus be useful to have indicators that could anticipate the success of treatment and more effectively guide therapeutic choices. We aimed to find predictive indicators of clinical improvement at 1 month after the start of rTMS treatment among the data collected during the care of patients with drug-resistant depression included in the Neuromodulation Unit of the Esquirol Hospital in Limoges since 2007. In total, 290 patients with a pharmaco-resistant depressive episode, according to the Hamilton Depression Rating Scale (HDRS) (score ≥8), before treatment who underwent a complete course of rTMS treatment and did not object to the use of their collected data were included. The clinical response in routine practice, corresponding to a decrease in the HDRS score of at least 50% from inclusion, was determined and complemented by interquartile analysis. A combination of factors predictive of clinical response during care, such as a short duration of the current depressive episode associated with a higher HDRS agitation item value (or a lower perceived sleepiness value) and a higher number of previous rTMS treatments, were identified as being useful in predicting the efficacy of rTMS treatment in routine clinical practice, thus facilitating the therapeutic choice for patients with drug-resistant depression.
    MeSH term(s) Depression ; Depressive Disorder, Major/therapy ; Humans ; Pharmaceutical Preparations ; Prefrontal Cortex ; Transcranial Magnetic Stimulation ; Treatment Outcome
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2021-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2609311-X
    ISSN 2158-3188 ; 2158-3188
    ISSN (online) 2158-3188
    ISSN 2158-3188
    DOI 10.1038/s41398-021-01555-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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