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  1. Article ; Online: Recent strategies for improving hemocompatibility and endothelialization of cardiovascular devices and inhibition of intimal hyperplasia.

    Feng, Li-An / Shi, Jie / Guo, Jing-Yue / Wang, Shu-Fang

    Journal of materials chemistry. B

    2022  Volume 10, Issue 20, Page(s) 3781–3792

    Abstract: Cardiovascular diseases have become one of the leading causes of mortality worldwide. Stents and artificial grafts have been used to treat cardiovascular diseases. Thrombosis and restenosis seriously impact the clinical outcome of stents and artificial ... ...

    Abstract Cardiovascular diseases have become one of the leading causes of mortality worldwide. Stents and artificial grafts have been used to treat cardiovascular diseases. Thrombosis and restenosis seriously impact the clinical outcome of stents and artificial vascular grafts. For the purpose of antithrombosis and anti-restenosis, numerous strategies have been developed to construct highly hemocompatible surfaces, enhance endothelialization, and inhibit intimal hyperplasia. Rapid endothelialization and inhibited intimal hyperplasia play an important role in artery repair after stent implantation and coronary artery bypass graft surgery. This review focuses on the recently developed strategies for improving the hemocompatibility and endothelialization of cardiovascular devices. We also introduce drug, gene and RNA delivery technologies for inhibiting intimal hyperplasia. The challenges and future perspectives about promoting endothelialization are also briefly discussed with the hope to help inspire further innovations.
    MeSH term(s) Blood Vessel Prosthesis ; Cardiovascular Diseases ; Cardiovascular System ; Humans ; Hyperplasia ; Stents
    Language English
    Publishing date 2022-05-25
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d2tb00478j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Recent strategies for improving hemocompatibility and endothelialization of cardiovascular devices and inhibition of intimal hyperplasia

    Feng, Li-An / Shi, Jie / Guo, Jing-Yue / Wang, Shu-Fang

    Journal of materials chemistry B. 2022 May 25, v. 10, no. 20

    2022  

    Abstract: Cardiovascular diseases have become one of the leading causes of mortality worldwide. Stents and artificial grafts have been used to treat cardiovascular diseases. Thrombosis and restenosis seriously impact the clinical outcome of stents and artificial ... ...

    Abstract Cardiovascular diseases have become one of the leading causes of mortality worldwide. Stents and artificial grafts have been used to treat cardiovascular diseases. Thrombosis and restenosis seriously impact the clinical outcome of stents and artificial vascular grafts. For the purpose of antithrombosis and anti-restenosis, numerous strategies have been developed to construct highly hemocompatible surfaces, enhance endothelialization, and inhibit intimal hyperplasia. Rapid endothelialization and inhibited intimal hyperplasia play an important role in artery repair after stent implantation and coronary artery bypass graft surgery. This review focuses on the recently developed strategies for improving the hemocompatibility and endothelialization of cardiovascular devices. We also introduce drug, gene and RNA delivery technologies for inhibiting intimal hyperplasia. The challenges and future perspectives about promoting endothelialization are also briefly discussed with the hope to help inspire further innovations.
    Keywords RNA ; biocompatibility ; coronary vessels ; drugs ; genes ; hyperplasia ; mortality ; thrombosis
    Language English
    Dates of publication 2022-0525
    Size p. 3781-3792.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d2tb00478j
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Correction: Chen et al. Multifunctional Injectable Hydrogel Loaded with Cerium-Containing Bioactive Glass Nanoparticles for Diabetic Wound Healing.

    Chen, Yue-Hua / Rao, Zhou-Feng / Liu, Yu-Jie / Liu, Xiang-Sheng / Liu, Yu-Fei / Xu, Lan-Ju / Wang, Ze-Qi / Guo, Jing-Yue / Zhang, Lin / Dong, Yun-Sheng / Qi, Chun-Xiao / Yang, Chao / Wang, Shu-Fang

    Biomolecules

    2024  Volume 14, Issue 3

    Abstract: The authors would like to replace Figure 4A of the following published paper [ ... ]. ...

    Abstract The authors would like to replace Figure 4A of the following published paper [...].
    Language English
    Publishing date 2024-02-27
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom14030283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Multifunctional Injectable Hydrogel Loaded with Cerium-Containing Bioactive Glass Nanoparticles for Diabetic Wound Healing.

    Chen, Yue-Hua / Rao, Zhou-Feng / Liu, Yu-Jie / Liu, Xiang-Sheng / Liu, Yu-Fei / Xu, Lan-Ju / Wang, Ze-Qi / Guo, Jing-Yue / Zhang, Lin / Dong, Yun-Sheng / Qi, Chun-Xiao / Yang, Chao / Wang, Shu-Fang

    Biomolecules

    2021  Volume 11, Issue 5

    Abstract: Diabetic foot wound healing is a major clinical problem due to impaired angiogenesis and bacterial infection. Therefore, an effective regenerative dressing is desiderated with the function of promoting revascularization and anti-bacteria. Herein, a ... ...

    Abstract Diabetic foot wound healing is a major clinical problem due to impaired angiogenesis and bacterial infection. Therefore, an effective regenerative dressing is desiderated with the function of promoting revascularization and anti-bacteria. Herein, a multifunctional injectable composite hydrogel was prepared by incorporation of the cerium-containing bioactive glass (Ce-BG) into Gelatin methacryloyl (GelMA) hydrogel. The Ce-BG was synthesized by combining sol-gel method with template method, which maintained spherical shape, chemical structure and phase constitution of bioactive glass (BG). The Ce-BG/GelMA hydrogels had good cytocompatibility, promoted endothelial cells migration and tube formation by releasing Si ion. In vitro antibacterial tests showed that 5 mol % CeO
    MeSH term(s) Animals ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Cell Line ; Cell Movement/drug effects ; Cerium/administration & dosage ; Cerium/chemistry ; Cerium/pharmacology ; Collagen/metabolism ; Diabetes Mellitus, Experimental/complications ; Diabetes Mellitus, Experimental/metabolism ; Gelatin/chemistry ; Human Umbilical Vein Endothelial Cells ; Humans ; Hydrogels ; Metal Nanoparticles ; Methacrylates/chemistry ; Mice ; Rats ; Streptozocin/adverse effects ; Wound Healing/drug effects
    Chemical Substances Anti-Bacterial Agents ; Hydrogels ; Methacrylates ; gelatin methacryloyl ; Cerium (30K4522N6T) ; Streptozocin (5W494URQ81) ; Gelatin (9000-70-8) ; Collagen (9007-34-5)
    Language English
    Publishing date 2021-05-08
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom11050702
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Surgical resection improves long-term survival of patients with hepatocellular carcinoma across different Barcelona Clinic Liver Cancer stages.

    Guo, Hui / Wu, Tao / Lu, Qiang / Li, Miaojing / Guo, Jing-Yue / Shen, Yuan / Wu, Zheng / Nan, Ke-Jun / Lv, Yi / Zhang, Xu-Feng

    Cancer management and research

    2018  Volume 10, Page(s) 361–369

    Abstract: Objectives: Surgical resection remains a controversial treatment for hepatocellular carcinoma (HCC) within different Barcelona Clinic Liver Cancer (BCLC) stages. The objective of this study was to evaluate the long-term outcome of patients undergoing ... ...

    Abstract Objectives: Surgical resection remains a controversial treatment for hepatocellular carcinoma (HCC) within different Barcelona Clinic Liver Cancer (BCLC) stages. The objective of this study was to evaluate the long-term outcome of patients undergoing surgical resection (SR) compared to non-surgical treatments across different BCLC stages.
    Patients and methods: One thousand four hundred forty-three HCC patients within BCLC 0, A, B and C stages were identified. Overall survival was compared by log-rank test among patients within different BCLC stages and among patients receiving different treatments (SR vs locoregional therapy [LRT] vs best supportive care). Propensity score matching analysis was introduced to mitigate the confounding biases between the groups.
    Results: The median survival time of the patients diminished from early, intermediate to advanced BCLC stages (BCLC 0-A 43 [range 0-100] months vs BCLC B 32 [range 0-100] months vs BCLC C 27 [range 0-90] months, all
    Conclusion: Surgical resection should be considered as a radical treatment for selected HCC patients regardless of the BCLC stages when appropriate.
    Language English
    Publishing date 2018-02-21
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2508013-1
    ISSN 1179-1322
    ISSN 1179-1322
    DOI 10.2147/CMAR.S152707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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