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  1. Article: Synthesis of MPEG-b-PLLA Diblock Copolymers and Their Crystallization Performance with PDLA and PLLA Composite Films.

    Wu, Wenjing / Wu, Weixin / Guo, Mingwei / Wang, Ruizhe / Wang, Xuanxuan / Gao, Qinwei

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 9

    Abstract: Methoxy poly(ethylene glycol)-block-poly(L-lactide) (MPEG-b-PLLA) has a wide range of applications in pharmaceuticals and biology, and its structure and morphology have been thoroughly studied. In the experiment, we synthesized MPEG-b-PLLA with different ...

    Abstract Methoxy poly(ethylene glycol)-block-poly(L-lactide) (MPEG-b-PLLA) has a wide range of applications in pharmaceuticals and biology, and its structure and morphology have been thoroughly studied. In the experiment, we synthesized MPEG-b-PLLA with different block lengths using the principle of ring-opening polymerization by controlling the amount of lactic acid added. The thermodynamic properties of copolymers and the crystallization properties of blends were studied separately. The crystallization kinetics of PDLA/MPEG-b-PLA and PLLA/MPEG-b-PLA composite films were studied using differential scanning calorimetry (DSC). The results indicate that the crystallization kinetics of composite films are closely related to the amount of block addition. The crystallinity of the sample first increases and then decreases with an increase in MPEG-b-PLLA content. These results were also confirmed in polarized optical microscope (POM) and wide-angle X-ray diffraction (WAXD) tests. When 3% MPEG-b-PLLA was added to the PDLA matrix, the blend exhibited the strongest crystallization performance.
    Language English
    Publishing date 2024-04-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17092105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Competitive Mechanism of Stereocomplexes and Homocrystals in High-Performance Symmetric and Asymmetric Poly(lactic acid) Enantiomers: Qualitative Methods.

    Guo, Mingwei / Wu, Wenjing / Wu, Weixin / Gao, Qinwei

    ACS omega

    2022  Volume 7, Issue 45, Page(s) 41412–41425

    Abstract: To systematically explore the critical contributions of both molecular weights and crystallization temperature and chain length and molar ratios to the formation of stereocomplexes (SCs), our group quantitatively prepared a wide MW range of symmetric and ...

    Abstract To systematically explore the critical contributions of both molecular weights and crystallization temperature and chain length and molar ratios to the formation of stereocomplexes (SCs), our group quantitatively prepared a wide MW range of symmetric and asymmetric poly(lactic acid) (PLA) racemic blends, which contains L-MW PLLA with
    Language English
    Publishing date 2022-11-07
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c05198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Recent advances in enhancing stereocomplexation between poly(lactide) enantiomeric chains.

    Guo, Mingwei / Wu, Weixin / Wu, Wenjing / Wang, Ruizhe / Huang, Liming / Gao, Qinwei

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 27, Page(s) 17737–17758

    Abstract: Over the past three decades, its excellent biodegradability and biocompatibility have enabled poly(lactide) (PLA) to be extensively explored as a replacement for oil-based thermoplastics in biomedical and industrial applications. However, PLA ... ...

    Abstract Over the past three decades, its excellent biodegradability and biocompatibility have enabled poly(lactide) (PLA) to be extensively explored as a replacement for oil-based thermoplastics in biomedical and industrial applications. However, PLA homopolymers have "facilitative" limitations such as low mechanical properties, low processing temperatures, slow recrystallization, and insufficient crystallinity, which have usually hindered commercial PLA in industrial and biomedical applications. The formation of stereo-complexation between enantiomeric poly(L-lactide) (PLLA) and poly(D-lactide) (PDLA) chains offers an effective approach to PLA-based engineering materials with improved properties. In this review, we have understandably summarized recent progress in improving the SC crystallization of PLA-based plastics into two aspects,
    Language English
    Publishing date 2023-07-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp01003a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The effects of weathering of coal-bearing stratum on the transport and transformation of DIC in karst watershed

    Huang, Jiangxun / Li, Qingguang / Wu, Pan / Wang, Shilu / Guo, Mingwei / Liu, Kun

    Science of the total environment. 2022 Sept. 10, v. 838

    2022  

    Abstract: The mining of medium- to high‑sulfur coal in karst areas has led to serious acidification problems in surface water, thus encouraging a re-evaluation of DIC transformation and CO₂ source-sink relationships in karst watersheds. The weathering of limestone ...

    Abstract The mining of medium- to high‑sulfur coal in karst areas has led to serious acidification problems in surface water, thus encouraging a re-evaluation of DIC transformation and CO₂ source-sink relationships in karst watersheds. The weathering of limestone and sulfide-rich coal measures jointly influence the pH of the Huatan River in karst areas in Southwest China, which is lower in the rainy season and higher in the dry season. Due to CO₂ degassing, DIC concentration tends to decrease along the flow direction, while δ¹³C-DIC gradually becomes heavier. In general, DIC transformation in the Huatan River is controlled by AMD input, CO₂ degassing, organic matter (OM) degradation, and the dissolution and precipitation balance of carbonate minerals in different seasons. In spring, the mineralization of OM from terrestrial and domestic sewage gradually enhances and replenishes DIC in the water. As the pH increases in this season, the capacity for buffering CO₂ increases. Meanwhile, OM degradation generates a large amount of CO₂ in summer, and carbonic acid begins to dissolve limestone. In autumn, the pH decreases due to the enhanced weathering of sulfide-rich coal measures and the mass input of AMD. Thus, the river shows the ability to drive CO₂ outgassing. In winter, CO₂ degassing gradually weakens, DIC concentration is at its lowest, and δ¹³C-DIC reaches the heaviest value.
    Keywords acidification ; autumn ; carbon dioxide ; carbonates ; carbonic acid ; coal ; dry season ; environment ; karsts ; limestone ; mineralization ; organic matter ; pH ; rivers ; sewage ; spring ; summer ; surface water ; watersheds ; wet season ; winter ; China
    Language English
    Dates of publication 2022-0910
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2022.156436
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    In stock of ZB MED Bonn / Germany

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  5. Article ; Online: Role of the Branched PEG-

    Guo, Mingwei / Zhao, Zhifeng / Xie, Zhongyuan / Wu, Weixin / Wu, Wenjing / Gao, Qinwei

    Langmuir : the ACS journal of surfaces and colloids

    2022  

    Abstract: The isothermal crystallization behavior and corresponding morphology evolution of poly(d-lactic acid) (PDLA) blends with ... ...

    Abstract The isothermal crystallization behavior and corresponding morphology evolution of poly(d-lactic acid) (PDLA) blends with PLLA
    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.2c02867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Synthesis and Properties of Nitrogen-Doped Carbon Quantum Dots Using Lactic Acid as Carbon Source.

    Chang, Kaixin / Zhu, Qianjin / Qi, Liyan / Guo, Mingwei / Gao, Woming / Gao, Qinwei

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 2

    Abstract: Nitrogen-doped carbon quantum dots (N-CQDs) were synthesized in a one-step hydrothermal technique utilizing L-lactic acid as that of the source of carbon and ethylenediamine as that of the source of nitrogen, and were characterized using dynamic light ... ...

    Abstract Nitrogen-doped carbon quantum dots (N-CQDs) were synthesized in a one-step hydrothermal technique utilizing L-lactic acid as that of the source of carbon and ethylenediamine as that of the source of nitrogen, and were characterized using dynamic light scattering, X-ray photoelectron spectroscopy ultraviolet-visible spectrum, Fourier-transformed infrared spectrum, high-resolution transmission electron microscopy, and fluorescence spectrum. The generated N-CQDs have a spherical structure and overall diameters ranging from 1-4 nm, and their surface comprises specific functional groups such as amino, carboxyl, and hydroxyl, resulting in greater water solubility and fluorescence. The quantum yield of N-CQDs (being 46%) is significantly higher than that of the CQDs synthesized from other biomass in literatures. Its fluorescence intensity is dependent on the excitation wavelength, and N-CQDs release blue light at 365 nm under ultraviolet light. The pH values may impact the protonation of N-CQDs surface functional groups and lead to significant fluorescence quenching of N-CQDs. Therefore, the fluorescence intensity of N-CQDs is the highest at pH 7.0, but it decreases with pH as pH values being either more than or less than pH 7.0. The N-CQDs exhibit high sensitivity to Fe
    Language English
    Publishing date 2022-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15020466
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  7. Article ; Online: The effects of weathering of coal-bearing stratum on the transport and transformation of DIC in karst watershed.

    Huang, Jiangxun / Li, Qingguang / Wu, Pan / Wang, Shilu / Guo, Mingwei / Liu, Kun

    The Science of the total environment

    2022  Volume 838, Issue Pt 4, Page(s) 156436

    Abstract: The mining of medium- to high‑sulfur coal in karst areas has led to serious acidification problems in surface water, thus encouraging a re-evaluation of DIC transformation and ... ...

    Abstract The mining of medium- to high‑sulfur coal in karst areas has led to serious acidification problems in surface water, thus encouraging a re-evaluation of DIC transformation and CO
    MeSH term(s) Calcium Carbonate ; Carbon/analysis ; Carbon Dioxide ; China ; Coal ; Environmental Monitoring ; Rivers ; Sulfides ; Water
    Chemical Substances Coal ; Sulfides ; Water (059QF0KO0R) ; Carbon Dioxide (142M471B3J) ; Carbon (7440-44-0) ; Calcium Carbonate (H0G9379FGK)
    Language English
    Publishing date 2022-06-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2022.156436
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner.

    Meng, Meiyao / Cao, Yuxiang / Qiu, Jin / Shan, Guangyu / Wang, Yingwen / Zheng, Ying / Guo, Mingwei / Yu, Jian / Ma, Yuandi / Xie, Cen / Hu, Cheng / Xu, Lingyan / Mueller, Elisabetta / Ma, Xinran

    Metabolism: clinical and experimental

    2024  Volume 152, Page(s) 155784

    Abstract: Background and aim: Triglyceride (TG) levels are closely related to obesity, fatty liver and cardiovascular diseases, while the regulatory factors and mechanism for triglyceride homeostasis are still largely unknown. Zinc Finger Protein 638 (ZNF638) is ... ...

    Abstract Background and aim: Triglyceride (TG) levels are closely related to obesity, fatty liver and cardiovascular diseases, while the regulatory factors and mechanism for triglyceride homeostasis are still largely unknown. Zinc Finger Protein 638 (ZNF638) is a newly discovered member of zinc finger protein family for adipocyte function in vitro. The aim of the present work was to investigate the role of ZNF638 in regulating triglyceride metabolism in mice.
    Methods: We generated ZNF638 adipose tissue specific knockout mice (ZNF638 FKO) by cross-breeding ZNF638 flox to Adiponectin-Cre mice and achieved adipose tissue ZNF638 overexpression via adenoviral mediated ZNF638 delivery in inguinal adipose tissue (iWAT) to examined the role and mechanisms of ZNF638 in fat biology and whole-body TG homeostasis.
    Results: Although ZNF638 FKO mice showed similar body weights, body composition, glucose metabolism and serum parameters compared to wild-type mice under chow diet, serum TG levels in ZNF638 FKO mice were increased dramatically after refeeding compared to wild-type mice, accompanied with decreased endothelial lipoprotein lipase (LPL) activity and increased lipid absorption of the small intestine. Conversely, ZNF638 overexpression in iWAT reduced serum TG levels while enhanced LPL activity after refeeding in female C57BL/6J mice and obese ob/ob mice. Specifically, only female mice exhibited altered TG metabolism upon ZNF638 expression changes in fat. Mechanistically, RNA-sequencing analysis revealed that the TG regulator angiopoietin-like protein 8 (Angptl8) was highly expressed in iWAT of female ZNF638 FKO mice. Neutralizing circulating ANGPTL8 in female ZNF638 FKO mice abolished refeeding-induced TG elevation. Furthermore, we demonstrated that ZNF638 functions as a transcriptional repressor by recruiting HDAC1 for histone deacetylation and broad lipid metabolic gene suppression, including Angptl8 transcription inhibition. Moreover, we showed that the sexual dimorphism is possibly due to estrogen dependent regulation on ZNF638-ANGPTL8 axis.
    Conclusion: We revealed a role of ZNF638 in the regulation of triglyceride metabolism by affecting Angptl8 transcriptional level in adipose tissue with sexual dimorphism.
    MeSH term(s) Animals ; Female ; Mice ; Adipose Tissue/metabolism ; Angiopoietin-Like Protein 8 ; DNA-Binding Proteins/metabolism ; Lipid Metabolism/genetics ; Mice, Inbred C57BL ; Mice, Knockout ; Obesity/genetics ; Obesity/metabolism ; RNA-Binding Proteins/metabolism ; Transcription Factors/metabolism ; Triglycerides/metabolism ; Zinc Fingers
    Chemical Substances Angiopoietin-Like Protein 8 ; ANGPTL8 protein, mouse ; DNA-Binding Proteins ; RNA-Binding Proteins ; Transcription Factors ; Triglycerides ; ZNF638 protein, mouse
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80230-x
    ISSN 1532-8600 ; 0026-0495
    ISSN (online) 1532-8600
    ISSN 0026-0495
    DOI 10.1016/j.metabol.2024.155784
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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.316: Show issues Location:
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  9. Article: Erythrophagocytosis by Neutrophil and Monocyte in Autoimmune Hemolytic Anemia After Infection.

    Lian, Xiaoqiang / Guo, Mingwei / Hao, Jihong

    Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

    2019  Volume 36, Issue 2, Page(s) 444–445

    Language English
    Publishing date 2019-10-26
    Publishing country India
    Document type Journal Article
    ZDB-ID 2422370-0
    ISSN 0974-0449 ; 0971-4502
    ISSN (online) 0974-0449
    ISSN 0971-4502
    DOI 10.1007/s12288-019-01226-2
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  10. Article ; Online: A fluorometric and colorimetric approach for the rapid detection of berberine hydrochloride based on an anionic polythiophene derivative.

    Gao, Xiao / Guo, Mingwei / Liu, Ming / Zhang, Li / Yao, Zhiyi

    Luminescence : the journal of biological and chemical luminescence

    2020  Volume 36, Issue 3, Page(s) 668–673

    Abstract: In this report, we develop a dual-output sensor with fluorometric and colorimetric responses, for the rapid and simple detection of berberine hydrochloride (BRH) in 100% aqueous solution based on an anionic polythiophene derivative, poly(2-(2-(4- ... ...

    Abstract In this report, we develop a dual-output sensor with fluorometric and colorimetric responses, for the rapid and simple detection of berberine hydrochloride (BRH) in 100% aqueous solution based on an anionic polythiophene derivative, poly(2-(2-(4-methylthiophen-3-yloxy)-ethyl) malonic acid) (PTMA). The sensing performance and mechanism were carefully examined by absorption and emission spectra. It can be applied to quantitatively detect BRH in aqueous solution with a detection limit 0.27 μM. The appealing performance of the sensor was demonstrated to originate from the electrostatic and π-π interactions between PTMA and BRH, which promoted the conformational change and aggregation of the PTMA backbone. Moreover, this method allowed rapid detection of BRH in urine samples and BRH tablets with high accuracy.
    MeSH term(s) Berberine ; Colorimetry ; Polymers ; Thiophenes
    Chemical Substances Polymers ; Thiophenes ; Berberine (0I8Y3P32UF) ; polythiophene (25233-34-5)
    Language English
    Publishing date 2020-12-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1470995-8
    ISSN 1522-7243 ; 1522-7235 ; 1099-1271
    ISSN (online) 1522-7243
    ISSN 1522-7235 ; 1099-1271
    DOI 10.1002/bio.3986
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2962: Show issues Location:
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